Aggressive Cutaneous Squamous Cell Carcinoma of the Head and Neck: A Review.

Non-melanoma skin cancer of the head and neck (NMSCHN) is one of the most common malignancies worldwide, and its incidence is growing at a significant rate. It has been found to be aggressive in its spread and has the capacity to metastasize to regional lymph nodes. Cutaneous squamous cell carcinoma (cSCC) has a considerably high mortality rate. It has remarkable characteristics: diameter >2 cm, depth >5 mm, high recurrence, perineural invasion, and locoregional metastases. Aggressive cSCC lesions most commonly metastasize to the parotid gland. Also, immunocompromised patients have a higher risk of developing this aggressive cancer along with the worst prognostic outcomes. It is very important to discuss and assess the risk factors, prognostic factors, and outcomes of patients with cSCC, which will give clinicians future directives for making modifications to their treatment plans. The successful treatment of aggressive cSCC of the head and neck includes early detection and diagnosis, surgery alone or adjuvant chemotherapy, and radiotherapy as required. Multimodal therapy options should be considered by clinicians for better outcomes of aggressive cSCC of the head and neck.

Multiple intraosseous cervical pneumatocysts: A case report of a rare incidental finding on cone-beam computed tomography.

This report presents a case of cervical pneumatocysts as an incidental finding on cone-beam computed tomography. Pneumatocysts are gas-containing lesions of unknown etiology. They usually present in the ilium or sacrum, adjacent to the sacroiliac joint. In the literature, 21 case reports have described cervical pneumatocysts. Cervical pneumatocysts should be differentiated from other lesions, such as osteomyelitis, osteonecrosis, and neoplasms, as well as post-traumatic and post-surgical cases. Computed tomography, cone-beam computed tomography, and magnetic resonance imaging are appropriate tools to diagnose cervical pneumatocysts.

Developing mobile phone text messages for tobacco risk communication among college students: a mixed methods study.

BACKGROUND: Engaging young adults for the purpose of communicating health risks associated with nicotine and tobacco use can be challenging since they comprise a population heavily targeted with appealing marketing by the evolving tobacco industry. The Food and Drug Administration seeks novel ways to effectively communicate risks to warn about using these products. This paper describes the first step in developing a text messaging program delivered by smartphones that manipulate three messaging characteristics (i.e., depth, framing, and appeal). METHODS: Perceptions of community college students were described after previewing text messages designed to inform about risks of using conventional and new tobacco products. Thirty-one tobacco users and nonusers, aged 18-25 participated in five focus discussions held on two community college campuses. Attendees reviewed prototype messages and contributed feedback about text message structure and content. Qualitative data were coded and analyzed using NVivo Version 10. RESULTS: Most participants were female and two-thirds were ethnic minorities. A variety of conventional and new tobacco products in the past month were used by a third of participants. Three identified domains were derived from the qualitative data. These included perceived risks of using tobacco products, receptivity to message content, and logistical feedback regarding the future message campaign. CONCLUSION: Overall, participants found the messages to be interesting and appropriate. A gap in awareness of the risks of using new tobacco products was revealed. Feedback on the prototype messages was incorporated into message revisions. These findings provided preliminary confirmation that the forthcoming messaging program will be appealing to young adults.

Dental care in Texas: An opportunity for implementing a comprehensive and patient-centric approach with special emphasis on cancer patients and survivors.

OBJECTIVE: To examine practices of dentists in Texas providing dental/oral care to cancer patients. METHOD: Dental providers in Texas were invited via email to participate in an exploratory cross-sectional study. A non-probability voluntary convenience sampling procedure was used to recruit the sample. The online, anonymous, self-reported survey included questions to capture demographics, type of dental practice, services provided, and number of cancer patients. The study was approved by the Institutional Review Board of The university of Texas MD Anderson Cancer Center. RESULT: A total of 655 dentists completed the questionnaire items. Results revealed that 62% of the respondents were 51-65 years old, predominantly (68%) male, Caucasian (81%) with their dental degrees awarded in the state of Texas (77%). 91% of the dentists provide dental care to patients who are currently undergoing cancer treatment or have a history of cancer. However, 80% of the dental providers do not teach oral self-exam to their patients, which may include cancer survivors or those undergoing cancer treatment, while 32% dentists do not deliver brief interventions for effectively motivating and assisting tobacco users to quit. CONCLUSION: Because Texas, especially Houston, is known for world-class cancer care, dentists in the state are more likely to provide dental care to oncologic patients, especially emergency dental procedures in cancer patients facing some of the side effects of cancer treatment. Careful monitoring of oral health and reducing tobacco use are especially important during and after cancer therapy to prevent, detect, and treat complications as soon as possible. A further step in oral care for cancer patients and survivors is to train patients how to perform regular oral self-examination and to provide tobacco users with cessation counseling as part of their dental/oral treatment. These simple but comprehensive approaches, along with regular dental visits, will positively impact the health-related outcomes for cancer patients, enhancing both survival and quality of life.

An investigation of first-order transition across charge ordered and ferromagnetic phases in Gd(0.5)Sr(0.5)MnO3 single crystals by magnetic and magnetotransport studies.

Gadolinium strontium manganite single crystals of the composition Gd(0.5)Sr(0.5)MnO(3) were grown using the optical float zone method. We report here the magnetic and magnetotransport properties of these crystals. A large magnetoresistance ∼10(9)% was observed at 45 K under the application of a 110 kOe field. We have observed notable thermomagnetic anomalies such as open hysteresis loops across the broadened first-order transition between the charge order insulator and the ferromagnetic metallic phase while traversing the magnetic field-temperature (H-T) plane isothermally or isomagnetically. In order to discern the cause of these observed anomalies, the H-T phase diagram for Gd(0.5)Sr(0.5)MnO(3) is formulated using the magnetization-field (M-H), magnetization-temperature (M-T) and resistance-temperature (R-T) measurements. The temperature dependence of the critical field (i.e. H(up), the field required for transformation to the ferromagnetic metallic phase) is non-monotonic. We note that the non-monotonic variation of the supercooling limit is anomalous according to the classical concepts of the first-order phase transition. Accordingly, H(up) values below ∼20 K are unsuitable to represent the supercooling limit. It is possible that the nature of the metastable states responsible for the observed open hysteresis loops is different from that of the supercooled ones.