RESUMEN
The technique of performing interferometry with two optical frequency combs is used by an increasing number of research groups and even for field deployed commercial applications. Real-time interferogram acquisition, correction, and averaging are, however, still not broadly accessible. This limits the deployment and wider adoption of this high resolution, high sensitivity technique. We herein introduce and describe a freely available correction software performing real-time processing on a graphics processing unit.
RESUMEN
Blood oxygen level-dependent functional magnetic resonance imaging (BOLD fMRI) arises from a physiological and physical cascade of events taking place at the level of the cortical microvasculature which constitutes a medium with complex geometry. Several analytical models of the BOLD contrast have been developed, but these have not been compared directly against detailed bottom-up modeling methods. Using a 3D modeling method based on experimentally measured images of mice microvasculature and Monte Carlo simulations, we quantified the accuracy of two analytical models to predict the amplitude of the BOLD response from 1.5 to 7 T, for different echo time (TE) and for both gradient echo and spin echo acquisition protocols. We also showed that accounting for the tridimensional structure of the microvasculature results in more accurate prediction of the BOLD amplitude, even if the values for SO2 were averaged across individual vascular compartments. A secondary finding is that modeling the venous compartment as two individual compartments results in more accurate prediction of the BOLD amplitude compared with standard homogenous venous modeling, arising from the bimodal distribution of venous SO2 across the microvasculature in our data.
RESUMEN
Systematic errors are observed in dual comb spectroscopy when pulses from the two sources travel in a common fiber before interrogating the sample of interest. When sounding a molecular gas, these errors distort both the line shapes and retrieved concentrations. Simulations of dual comb interferograms based on a generalized nonlinear Schrodinger equation highlight two processes for these systematic errors. Self-phase modulation changes the spectral content of the field interrogating the molecular response but affects the recorded spectral baseline and absorption features differently, leading to line intensity errors. Cross-phase modulation modifies the relative inter-pulse delay, thus introducing interferogram sampling errors and creating a characteristic asymmetric distortion on spectral lines. Simulations capture the shape and amplitude of experimental errors which are around 0.1% on spectral transmittance residuals for 10 mW of total average power in 10 meters of common fiber, scaling up to above 0.6% for 20 mW and 60 m.
RESUMEN
We introduce a dual-comb spectrometer based on erbium fiber oscillators at 250â MHz that operates in the 7.5-11.5â µm spectral range over optical bandwidths up to 9â THz with a multi-kHz acquisition rate. Over an observation bandwidth of 0.8â THz, the signal-to-noise ratio per spectral point reaches 168â Hz0.5 at an acquisition rate of 26â kHz, which allows the investigation of transient processes in the gas phase at high temporal resolution. The system also represents an attractive solution for multi-species atmospheric gas detection in open paths due to the water transparency of the spectral window, the use of thermo-electrically cooled detectors, and the out-of-loop phase correction of the interferograms.
RESUMEN
Detector non-linearity is an important factor limiting the maximal power and hence the signal-to-noise ratio (SNR) in dual-comb interferometry. To increase the SNR without overwhelming averaging time, photodetector non-linearity must be properly handled for high input power. Detectors exhibiting nonlinear behavior can produce linear dual-comb interferograms if the area of the detector's impulse response does not saturate and if the overlap between successive time-varying impulse responses is properly managed. Here, a high bandwidth non-amplified balanced photodetector is characterized in terms of its impulse response to high intensity short pulses to exemplify the conditions. With a 23.5 mW average power on each detector in a balanced pair, nonlinear spectral artifacts are at least 40 dB below the spectral baseline. Absorption lines of carbon dioxide are measured to reveal lines discrepancies smaller than 0.1% with HITRAN. A spectral shape independent formulation for the dual-comb figure of merit is proposed, reaching here 7.2 × 107 Hz1/2 limited by laser relative intensity noise, but corresponding to an ideal, shot-noise limited, figure of merit for an equivalent 0.85 mW average power per comb.
RESUMEN
A method to measure and correct for spectral baseline fluctuations in dual-comb interferometry is presented. Fluctuations can be measured from the amplitude of beat notes between combs and a continuous wave laser or from a separate measurement of the combs' repetition rates, filtered around the spectral region of interest. Amplitude-dependent spectral variations are characterized using low-resolution Fourier transforms around the centerburst of several interferograms, and a nonstationary filter is applied to properly account for the combs' variations during the measurement. This allows removal of this source of statistical, as well as systematic, errors.