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The emerging market demand for high-energy-density of energy storage devices is pushing the disposal of end-of-life LiCoO2 (LCO) to shift toward sustainable upgrading into structurally stable high-voltage cathode materials. Herein, an integrated bulk and surface commodification strategy is proposed to render spent LCO (S-LCO) to operate at high voltages, involving bulk Mn doping, near surface P gradient doping, and Li3PO4/CoP (LPO/CP) coating on the LCO surface to yield upcycled LCO (defined as MP-LCO@LPO/CP). Benefiting from hybrid surface coating with Li+-conductive Li3PO4 (LPO) and electron conductive CoP (CP) coupled with Mn and P co-doping, the optimized MP-LCO@LPO/CP cathode exhibits enhanced high-voltage performance, delivering an initial discharge capacity of 218.8 mAh g-1 at 0.2 C with excellent capacity retention of 80.9% (0.5 C) after 200 cycles at a cut-off voltage of 4.6 V, along with 96.3% of capacity retention over 100 cycles at 4.5 V. These findings may afford meaningful construction for the upcycling of commercial S-LCO into next-generation upmarket cathode materials through the elaborate surface and bulk modification design.
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The development of highly active, reusable catalysts for aqueous-phase reactions is challenging. Herein, metallic nickel is encapsulated in a nitrogen-doped carbon-silica composite (SiO2@Ni@NC) as a catalyst for the selective hydrogenation of vanillin in aqueous media. The constructed catalyst achieved 99.8% vanillin conversion and 100% 4-hydroxymethyl-2-methoxyphenol selectivity at room temperature. Based on combined scanning transmission electron microscopy, X-ray photoelectron spectroscopy, and Raman analyses, the satisfactory catalytic performance is attributed to the composite structure consisting of an active metal, carbon, and silica. The hydrophilic silica core promoted dispersion of the catalyst in aqueous media. Moreover, the external hydrophobic NC layer has multiple functions, including preventing oxidation or leaching of the internal metal, acting as a reducing agent to reduce the internal metal, regulating the active-site microenvironment by enriching the concentrations of H2 and organic reactants, and modifying the electronic structure of the active metal via metal-support interactions. Density functional theory calculations indicated that NC facilitates vanillin adsorption and hydrogen dissociation to promote aqueous-phase hydrogenation. This study provides an efficient strategy for constructing encapsulated Ni-based amphiphilic catalysts to upgrade biomass-derived compounds.
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CONTEXT: Asphalt, a polymer mixture composed of various hydrocarbons, is extensively utilized due to its excellent performance. To evaluate the sensitivity of asphalt concrete to chloride salt damage at the nanoscale, considering the anisotropy of aggregate mineral crystal orientation, molecular dynamic simulations were employed to model the interface interactions between asphalt and aggregate mineral components (silica and calcite) under chloride salt exposure. The wetting processes of water droplets and chloride salt droplets on different crystal surfaces of silica and calcite were analyzed. Furthermore, the adhesive energy, decohesion energy, degradation ratio, and energy ratio of the interaction model between asphalt and aggregate mineral interfaces were analyzed to reveal the variations in the interfaces between the two components. The results demonstrated that the anisotropy of the minerals significantly affects the adhesion energy of asphalt and aggregate. Moreover, the surface hydrophilicity of calcite was larger than that of silica. The interfacial adhesion energy of asphalt-calcite was larger than that of asphalt-silica under dry condition and chloride salt attack, and the interfacial adhesion energy of both asphalt and mineral decreased with the increase of chloride salt concentration. The degradation ratio and energy ratio values of asphalt and calcite were larger than those of asphalt and silica, and the anisotropy of the mineral surface affected the degradation ratio and energy ratio values. This study provides a new method and theoretical basis for further research on the damage mechanism and strengthening measures of asphalt-aggregate under chloride salt attack. METHODS: To investigate the interaction between asphalt and mineral aggregates under chloride salt erosion, models of asphalt, aggregate, and asphalt/aggregate composite systems were constructed using the Amorphous Cell module in Materials Studio 2020 software. Molecular dynamic simulations of the asphalt/aggregate composite system were then conducted using the Forcite module, employing the COMPASS II force field to describe atomic and molecular interactions. Initially, considering the crystal orientation and surface configuration of the aggregate minerals, the impact of mineral anisotropy on the asphalt-aggregate interface model was analyzed. Subsequently, by simulating the contact states of nano water droplets and chloride salt droplets with different mineral surfaces, the wetting characteristics of nano water droplets on silica and calcite surfaces were determined. Lastly, considering the corrosion effect of chloride solution at different concentrations, the adhesion energy, debonding energy, degradation ratio, and energy ratio of the asphalt-aggregate interface interaction model were analyzed.
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BACKGROUND: Postprocedural anticoagulation (PPA) is frequently administered after primary percutaneous coronary intervention in ST-segment-elevation myocardial infarction, although no conclusive data support this practice. METHODS: The RIGHT trial (Comparison of Anticoagulation Prolongation vs no Anticoagulation in STEMI Patients After Primary PCI) was an investigator-initiated, multicenter, randomized, double-blind, placebo-controlled, superiority trial conducted at 53 centers in China. Patients with ST-segment-elevation myocardial infarction undergoing primary percutaneous coronary intervention were randomly assigned by center to receive low-dose PPA or matching placebo for at least 48 hours. Before trial initiation, each center selected 1 of 3 PPA regimens (40 mg of enoxaparin once daily subcutaneously; 10 U·kg·h of unfractionated heparin intravenously, adjusted to maintain activated clotting time between 150 and 220 seconds; or 0.2 mg·kg·h of bivalirudin intravenously). The primary efficacy objective was to demonstrate superiority of PPA to reduce the primary efficacy end point of all-cause death, nonfatal myocardial infarction, nonfatal stroke, stent thrombosis (definite), or urgent revascularization (any vessel) within 30 days. The key secondary objective was to evaluate the effect of each specific anticoagulation regimen (enoxaparin, unfractionated heparin, or bivalirudin) on the primary efficacy end point. The primary safety end point was Bleeding Academic Research Consortium 3 to 5 bleeding at 30 days. RESULTS: Between January 10, 2019, and September 18, 2021, a total of 2989 patients were randomized. The primary efficacy end point occurred in 37 patients (2.5%) in both the PPA and placebo groups (hazard ratio, 1.00 [95% CI, 0.63 to 1.57]). The incidence of Bleeding Academic Research Consortium 3 to 5 bleeding did not differ between the PPA and placebo groups (8 [0.5%] vs 11 [0.7%] patients; hazard ratio, 0.74 [95% CI, 0.30 to 1.83]). CONCLUSIONS: Routine PPA after primary percutaneous coronary intervention was safe but did not reduce 30-day ischemic events. REGISTRATION: URL: https://www.clinicaltrials.gov; Unique identifier: NCT03664180.
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Infarto del Miocardio , Intervención Coronaria Percutánea , Infarto del Miocardio con Elevación del ST , Humanos , Anticoagulantes/efectos adversos , Enoxaparina/efectos adversos , Hemorragia/inducido químicamente , Hemorragia/tratamiento farmacológico , Heparina/efectos adversos , Infarto del Miocardio/tratamiento farmacológico , Recurrencia Local de Neoplasia/tratamiento farmacológico , Fragmentos de Péptidos/efectos adversos , Intervención Coronaria Percutánea/efectos adversos , Proteínas Recombinantes , Infarto del Miocardio con Elevación del ST/tratamiento farmacológico , Resultado del TratamientoRESUMEN
The utilization of Na2MnSiO4 as a Faraday electrode in hybrid capacitive deionization (HCDI) is investigated to achieve efficient desalination. The Na2MnSiO4/C (NMSO) materials were fabricated via a simple sol-gel method, in which the synthesis process was modulated by adjusting the volume ratio of ethanol to water. When maintaining the volume ratio of water to ethanol at 3:1, the resultant NMSO-3/1 exhibited expected salt adsorption capacity of 31.06 mg g-1 and salt adsorption rate of 20.43 mg g-1 min-1. This distinguished desalination performance was mainly attributed to its inherent multiple redox pairs, as well as the integration of ethanol, which enhanced both specific capacitance and hydrophilicity of the material. This study opens a new perspective for the development of highly efficient materials in HCDI.
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Electrocatalytic nitrate reduction reaction has attracted increasing attention due to its goal of low carbon emission and environmental protection. Here, we report an efficient NitRR catalyst composed of single Mn sites with atomically dispersed oxygen (O) coordination on bacterial cellulose-converted graphitic carbon (Mn-O-C). Evidence of the atomically dispersed Mn-(O-C2)4 moieties embedding in the exposed basal plane of carbon surface is confirmed by X-ray absorption spectroscopy. As a result, the as-synthesized Mn-O-C catalyst exhibits superior NitRR activity with an NH3 yield rate (RNH3) of 1476.9 ± 62.6 µg h-1 cm-2 at - 0.7 V (vs. reversible hydrogen electrode, RHE) and a faradaic efficiency (FE) of 89.0 ± 3.8% at - 0.5 V (vs. RHE) under ambient conditions. Further, when evaluated with a practical flow cell, Mn-O-C shows a high RNH3 of 3706.7 ± 552.0 µg h-1 cm-2 at a current density of 100 mA cm-2, 2.5 times of that in the H cell. The in situ FT-IR and Raman spectroscopic studies combined with theoretical calculations indicate that the Mn-(O-C2)4 sites not only effectively inhibit the competitive hydrogen evolution reaction, but also greatly promote the adsorption and activation of nitrate (NO3-), thus boosting both the FE and selectivity of NH3 over Mn-(O-C2)4 sites.
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The integration of highly active single atoms (SAs) and atom clusters (ACs) into an electrocatalyst is critically important for high-efficiency two-electron oxygen reduction reaction (2e- ORR) to hydrogen peroxide (H2 O2 ). Here we report a tandem impregnation-pyrolysis-etching strategy to fabricate the oxygen-coordinated Fe SAs and ACs anchored on bacterial cellulose-derived carbon (BCC) (FeSAs/ACs-BCC). As the electrocatalyst, FeSAs/ACs-BCC exhibits superior electrocatalytic activity and selectivity toward 2e- ORR, affording an onset potential of 0.78â V (vs. RHE) and a high H2 O2 selectivity of 96.5 % in 0.1â M KOH. In a flow cell reactor, the FeSAs/ACs-BCC also achieves high-efficiency H2 O2 production with a yield rate of 12.51±0.18â mol gcat -1 h-1 and a faradaic efficiency of 89.4 %±1.3 % at 150â mA cm-2 . Additionally, the feasibility of coupling the produced H2 O2 and electro-Fenton process for the valorization of ethylene glycol was explored in detail. The theoretical calculations uncover that the oxygen-coordinated Fe SAs effectively regulate the electronic structure of Fe ACs which are the 2e- ORR active sites, resulting in the optimal binding strength of *OOH intermediate for high-efficiency H2 O2 production.
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This paper investigates the power control and resource allocation problem in a simultaneously wireless information and power transfer (SWIPT)-based cognitive two-way relay network, in which two secondary users exchange information through a power splitting (PS) energy harvesting (EH) cognitive relay node underlay in a primary network. To enhance the secondary networks's transmission ability without detriment to the primary network, we formulate an optimization to maximize the minimum transmission rates of the cognitive users by jointly optimizing power allocation at the sources, the time allocation of transmission frames and power splitting at the relay, under the constraint that the transmission power of the cognitive network is set not to exceed the primary user interference threshold to ensure primary work performance. To efficiently solve this problem, a sub-optimal algorithm named the joint power control and resource allocation (JPCRA) scheme is proposed, in which we decouple the non-convex problem into convex problems and use alternative steps in the optimization algorithm to get final solutions. Numerical results reveal that the proposed scheme enhances transmission fairness and outperforms three traditional schemes.
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Since ferrous (Fe(II)) is the main form of plant absorption, traditional ferrous foliar fertilizers (TFFF) are widely used in modern agriculture. However, TFFF suffer from the shortcomings of weak antioxidant capacity (AC), low foliar adhesion efficiency (FAE), poor fertilizer utilization efficiency (FUE), and noncontrollable slow-release behavior. To overcome these limitations, an oxidation-resistant silicon nanosystem for intelligent controlled ferrous foliar delivery to crops was first developed by using environmentally friendly micro/nano structured hollow silicon as carrier, and combining with vitamin C (in situ antioxidant) to synthesize an oxidation-resistant ferrous foliar fertilizer (ORFFF) for ameliorating Fe-deficiency in crops and increasing crop yield. Compared with TFFF, the ORFFF has excellent ferrous AC (only 11.5% of Fe(II) was oxidized in ORFFF within 72 h), ultrahigh FAE (â¼84% of adhesion percentage (%) after two-times simulated rain rinsing), nutrient slow-release ability (720 h gradually release 100.6 mg·g-1), pH-controlled release ability (pH 3-8), and verified high biological safety (100% survival rate for zebrafish and earthworm). The pot experiments showed that ORFFF can correct the Fe-deficiency symptoms of tomato seedlings promptly compared with TFFF, and the FUE of ORFFF is 4.2 times that of TFFF. The specific pH responsiveness of ORFFF can control the slow-release rate of Fe(II) to satisfy the needs of Fe in varying crops and different growing periods of crops. This work provides a feasible way to achieve green and safe Fe supplementation for crops, reduce Fe fertilizer waste, avoid soil pollution caused by Fe fertilizer abuse, and promote the sustainable development of modern nanoagriculture.
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Antioxidantes , Silicio , Animales , Fertilizantes/análisis , Pez Cebra , Compuestos Ferrosos/farmacología , SueloRESUMEN
Versatile Video Coding (VVC) introduces many new coding technologies, such as quadtree with nested multi-type tree (QTMT), which greatly improves the efficiency of VVC coding. However, its computational complexity is higher, which affects the application of VVC in real-time scenarios. Aiming to solve the problem of the high complexity of VVC intra coding, we propose a low-complexity partition algorithm based on edge features. Firstly, the Laplacian of Gaussian (LOG) operator was used to extract the edges in the coding frame, and the edges were divided into vertical and horizontal edges. Then, the coding unit (CU) was equally divided into four sub-blocks in the horizontal and vertical directions to calculate the feature values of the horizontal and vertical edges, respectively. Based on the feature values, we skipped unnecessary partition patterns in advance. Finally, for the CUs without edges, we decided to terminate the partition process according to the depth information of neighboring CUs. The experimental results show that compared with VTM-13.0, the proposed algorithm can save 54.08% of the encoding time on average, and the BDBR (Bjøntegaard delta bit rate) only increases by 1.61%.
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Algoritmos , Espiración , Grabación en Video/métodos , Distribución Normal , ÁrbolesRESUMEN
Porous carbon materials have been regarded as a promising alternative to activated carbon for desalination via capacitive deionization (CDI) due to refined architectures and functionalities. However, it is still challenging to obtain a controlled hierarchical pore structure and considerable nitrogen-doped content by convenient method. Herein, nitrogen-doped hierarchical porous carbon foams (NHCFs) with different microstructural features, nitrogen contents and nitrogen species were successfully fabricated via a stepwise pyrolysis carbonization strategy using easily available melamine foam. Due to the synergistic effect of hierarchical porous structure and doped nitrogen, the optimized NHCF sample carbonized at 800â (NHCF-800) exhibited a maximum desalination capacity of 30.1 mg g-1 at the optimal operating parameters (500 mg/L NaCl solution, 1.2 V) and an excellent regeneration performance after 50 continuous adsorption-desorption cycles. Furthermore, density functional theory (DFT) was also conducted to elaborate the disparity of sodium adsorption energy among the nitrogen species for in-depth understanding, and it mainly benefits from the ascendency of the pyrrolic-N and pyridinic-N over the graphitic-N dopant. This work paves the way of rational regulation of nitrogen-doped process and hierarchical porous structure carbon as CDI electrode materials for desalination.
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The just noticeable difference (JND) model reflects the visibility limitations of the human visual system (HVS), which plays an important role in perceptual image/video processing and is commonly applied to perceptual redundancy removal. However, existing JND models are usually constructed by treating the color components of three channels equally, and their estimation of the masking effect is inadequate. In this paper, we introduce visual saliency and color sensitivity modulation to improve the JND model. Firstly, we comprehensively combined contrast masking, pattern masking, and edge protection to estimate the masking effect. Then, the visual saliency of HVS was taken into account to adaptively modulate the masking effect. Finally, we built color sensitivity modulation according to the perceptual sensitivities of HVS, to adjust the sub-JND thresholds of Y, Cb, and Cr components. Thus, the color-sensitivity-based JND model (CSJND) was constructed. Extensive experiments and subjective tests were conducted to verify the effectiveness of the CSJND model. We found that consistency between the CSJND model and HVS was better than existing state-of-the-art JND models.
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Increased cerebral blood flow resulting from altered capillary level autoregulation at high altitudes leads to capillary overperfusion and then vasogenic cerebral edema, which is the leading hypothesis of acute mountain sickness (AMS). However, studies on cerebral blood flow in AMS have been mostly restricted to gross cerebrovascular endpoints as opposed to the microvasculature. This study aimed to investigate ocular microcirculation alterations, the only visualized capillaries in the central neural system (CNS), during early-stage AMS using a hypobaric chamber. This study found that after high altitude simulation, the optic nerve showed retinal nerve fiber layer thickening (P=0.004-0.018) in some locations, and the area of the optic nerve subarachnoid space (P=0.004) enlarged. Optical coherence tomography angiography (OCTA) showed increased retinal radial peripapillary capillary (RPC) flow density (P=0.003-0.046), particularly on the nasal side of the nerve. The AMS-positive group had the largest increases in RPC flow density in the nasal sector (AMS-positive, Δ3.21±2.37; AMS-negative, Δ0.01±2.16, P=0.004). Among multiple ocular changes, OCTA increase in RPC flow density was associated with simulated early-stage AMS symptoms (beta=0.222, 95%CI, 0.009-0.435, P=0.042). The area under the receiver operating characteristics curve (AUC) for the changes in RPC flow density to predict early-stage AMS outcomes was 0.882 (95%CI, 0.746-0.998). The results further confirmed that overperfusion of microvascular beds is the key pathophysiologic change in early-stage AMS. RPC OCTA endpoints may serve as a rapid, noninvasive potential biomarker for CNS microvascular changes and AMS development during risk assessment of individuals at high altitudes.
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Mal de Altura , Humanos , Mal de Altura/diagnóstico por imagen , Retina/diagnóstico por imagen , Enfermedad Aguda , Angiografía con Fluoresceína/métodos , Capilares , Tomografía de Coherencia Óptica/métodosRESUMEN
The development of efficient electrocatalysts to generate key *NH2 and *CO intermediates is crucial for ambient urea electrosynthesis with nitrate (NO3 - ) and carbon dioxide (CO2 ). Here we report a liquid-phase laser irradiation method to fabricate symbiotic graphitic carbon encapsulated amorphous iron and iron oxide nanoparticles on carbon nanotubes (Fe(a)@C-Fe3 O4 /CNTs). Fe(a)@C-Fe3 O4 /CNTs exhibits superior electrocatalytic activity toward urea synthesis using NO3 - and CO2 , affording a urea yield of 1341.3±112.6â µg h-1 mgcat -1 and a faradic efficiency of 16.5±6.1 % at ambient conditions. Both experimental and theoretical results indicate that the formed Fe(a)@C and Fe3 O4 on CNTs provide dual active sites for the adsorption and activation of NO3 - and CO2 , thus generating key *NH2 and *CO intermediates with lower energy barriers for urea formation. This work would be helpful for design and development of high-efficiency dual-site electrocatalysts for ambient urea synthesis.
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Background: The effect of a single transradial guiding catheter (STGC) for culprit vessel percutaneous coronary intervention (PCI) first on door-to-balloon (D2B) time remains unclear. Materials and methods: Between February 2017 and July 2019, 560 patients with ST-elevation myocardial infarction (STEMI) were randomized into either the STGC group (n = 280) or the control group (n = 280) according to direct culprit vessel PCI with a STGC. In the STGC group, a dedicated transraidal guiding catheter (6F either MAC3.5 or JL3.5) was used for the treatment of electrocardiogram (ECG)-guided culprit vessel first and later contralateral angiography. In the control group, a universal diagnostic catheter (5F Tiger II) was used for complete coronary angiography, followed by guiding catheter selection for culprit vessel PCI. The primary endpoint was D2B time, and the secondary endpoint included catheterization laboratory door-to-balloon (C2B), procedural, fluoroscopy times, and major adverse cardiac events (MACE) at 30 days. Results: The median D2B time was significantly shorter in the STGC group compared to the control group (53.9 vs. 58.4 min; p = 0.003). The C2B, procedural, and fluoroscopy times were also shorter in the STGC group (C2B: 17.3 vs. 24.5 min, p < 0.001; procedural: 45.2 vs. 49.0 min, p = 0.012; and fluoroscopy: 9.7 vs. 11.3 min, p = 0.025). More patients achieved the goal of D2B time within 90 min (93.9% vs. 87.1%, p = 0.006) and 60 min (61.4% vs. 51.1%, p = 0.013) in the STGC group. Radial artery perforation (RAP) was significantly reduced in the STGC group compared with the control group (0.7% vs. 3.2%, P = 0.033). MACE at 30 days was similar (2.5% vs. 4.6%, P = 0.172) between the two groups. Conclusion: ECG-guided immediate intervention on culprit vessel with a STGC can reduce D2B, C2B, procedural, and fluoroscopy times (ECG-guided Immediate Primary PCI for Culprit Vessel to Reduce Door to Device Time; NCT03272451).
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Direct electrocatalytic oxidation of benzene has been regarded as a promising approach for achieving high-value phenol product, but remaining a huge challenge. Here an oxygen-coordinated nickel single-atom catalyst (Ni-O-C) is reported with bifunctional electrocatalytic activities toward the two-electron oxygen reduction reaction (2e- ORR) to H2 O2 and H2 O2 -assisted benzene oxidation to phenol. The Ni-(O-C2 )4 sites in Ni-O-C ar proven to be the catalytic active centers for bifunctional 2e- ORR and H2 O2 -assisted benzene oxidation processes. As a result, Ni-O-C can afford a benzene conversion as high as 96.4 ± 3.6% with a phenol selectivity of 100% and a Faradaic efficiency (FE) of 80.2 ± 3.2% with the help of H2 O2 in 0.1 m KOH electrolyte at 1.5 V (vs RHE). A proof of concept experiment with Ni-O-C concurrently as cathode and anode in a single electrochemical cell demonstrates a benzene conversion of 33.4 ± 2.2% with a phenol selectivity of 100% and a FE of 44.8 ± 3.0% at 10 mA cm-2 .
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In order to improve the library's ability of cross-platform information retrieval and data scheduling and distribution, a library cross-platform information retrieval system based on digital twin technology is designed. Using data warehouse decision support and data source structured query methods, the spectral characteristics of Library cross-platform information resources are extracted. Using the method of Hadoop data parallel loading, the library cross-platform operation data is divided into decision-making data, computing resource pool data, and Hadoop parallel loading data. A library cross-platform information digital twin parallel retrieval and information fusion feature matching model is established, and the retrieval channels are allocated through multiple complex and balanced task scheduling sequences. According to the queue configuration model of Library cross-platform information retrieval, the optimization design of Library cross-platform information retrieval system is realized. The simulation test results show that the designed system has good recall ability of cross-platform information retrieval data, and improves the utilization rate of cross-platform resources and the dynamic scheduling ability of online resources.
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Almacenamiento y Recuperación de la Información , Sistemas de Información , Programas InformáticosRESUMEN
In order to improve the Resource Recommendation and sharing ability of mobile library, an intelligent optimization model of Mobile Library Resource Recommendation Service Based on digital twin technology is proposed. Build the association rule feature distribution set of mobile library resource recommendation service, carry out text information retrieval in the process of Mobile Library Resource Recommendation and sharing, carry out semantic correlation feature registration according to the retrieval preference of mobile library reading user object, establish the association rule data set of mobile library reading user object preference for mobile library Resource Recommendation and sharing, carry out feature block processing, and analyze the library reader preference. Complete the collaborative filtering recommendation of Mobile Library Resource Recommendation sharing. The simulation results show that the collaborative recommendation under the intelligent optimization mode of mobile library resource recommendation service using this method has high accuracy and good confidence level, which improves the intelligent level of Mobile Library Resource Recommendation and user satisfaction.
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Almacenamiento y Recuperación de la Información , TecnologíaRESUMEN
BACKGROUND: Radial artery (RA) atherosclerosis in acute coronary syndrome (ACS) patients has not been systematically observed in vivo. The study aims to characterize plaque morphology and intimal hyperplasia of the RA in patients with ACS, using optical coherence tomography (OCT). METHODS: In this retrospective study involving 239 ACS patients underwent RA OCT without guidewire shadow, 3 groups were divided according to the following criteria: radial artery plaque (RAP) group included patients with fibrous, lipid or calcified plaque; patients without RAP were further classified into radial intimal hyperplasia (RIH) group (intima media thickness ratio [IMR] ≥ 1) or normal group (IMR < 1). The presence and characteristics of RAP and its related risk factors were identified. RESULTS: The RAP, RIH and normal groups included 76 (31.8%), 69 (28.9%) and 94 (39.3%) patients, respectively. Patients in RAP group were the oldest, compared with those in the RIH and normal groups (p < 0.001), and more frequently had triple vessel disease (p = 0.004). The percentage of plaque rupture (72.4% vs. 56.4%, p = 0.018) and calcification (42.1% vs. 27.6%, p = 0.026) at culprit lesion were significantly higher in patients with RAP than those without RAP. A total of 148 RAP were revealed by OCT, including fibrous (72, 48.6%), lipid (50, 33.8%) and calcified plaques (26, 17.6%). The microvessels were also frequently observed in the RAP group than that in RIH and normal groups (59.2% vs. 8.7% vs. 9.6%, p < 0.001). Multivariate logistic regression analysis showed that age, diabetes, and smoking history (all p < 0.05) were independent risk factors for RAP. CONCLUSIONS: In terms of insights gained from OCT, RA atherosclerosis is not uncommon in ACS patients by OCT, sharing several morphological characters with early coronary atherosclerosis. Aging, diabetes, and smoking are risk factors for RAP.
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Síndrome Coronario Agudo , Aterosclerosis , Enfermedad de la Arteria Coronaria , Placa Aterosclerótica , Síndrome Coronario Agudo/diagnóstico por imagen , Síndrome Coronario Agudo/etiología , Síndrome Coronario Agudo/patología , Aterosclerosis/diagnóstico por imagen , Aterosclerosis/patología , Grosor Intima-Media Carotídeo , Angiografía Coronaria , Enfermedad de la Arteria Coronaria/diagnóstico por imagen , Enfermedad de la Arteria Coronaria/patología , Vasos Coronarios/diagnóstico por imagen , Vasos Coronarios/patología , Humanos , Hiperplasia/patología , Lípidos , Arteria Radial/diagnóstico por imagen , Estudios Retrospectivos , Tomografía de Coherencia Óptica/métodosRESUMEN
High-performance transition metal chalcogenides (TMCs) as electrocatalysts for two-electron oxygen reduction reaction (2e-ORR) in alkaline medium are promising for hydrogen peroxide (H2 O2 ) production, but their synthesis remains challenging. In this work, a titanium-doped zinc-cobalt sulfide hollow superstructure (Ti-ZnCoS HSS) is rationally designed as an efficient electrocatalyst for H2 O2 electrosynthesis. Synthesized by using hybrid metal-organic frameworks (MOFs) as precursors after sulfidation treatment, the resultant Ti-ZnCoS HSS exhibits a hollow-on-hollow superstructure with small nanocages assembled around a large cake-like cavity. Both experimental and simulation results demonstrate that the polymetallic composition tailors the d-band center and binding energy with oxygen species. Moreover, the hollow superstructure provides abundant active sites and promotes mass and electron transfer. The synergistic d-band center and superstructure engineering at both atomic and nanoscale levels lead to the remarkable 2e-ORR performance of Ti-ZnCoS HSS with a high selectivity of 98%, activity (potential at 1 mA cm-2 of 0.774 V vs reversible hydrogen electrode (RHE)), a H2 O2 production rate of 675 mmol h-1 gcat -1 , and long-term stability in alkaline condition, among the best 2e-ORR electrocatalysts reported to date. This strategy paves the way toward the rational design of polymetallic TMCs as advanced 2e-ORR catalysts.