Asunto(s)
Ganglios Basales , Encéfalo , Hipertermia Inducida/métodos , Hipoxia Encefálica , Paro Cardíaco Extrahospitalario , Tomografía Computarizada por Rayos X/métodos , Ganglios Basales/irrigación sanguínea , Ganglios Basales/diagnóstico por imagen , Encéfalo/irrigación sanguínea , Encéfalo/diagnóstico por imagen , Encéfalo/patología , Circulación Cerebrovascular , Toma de Decisiones Clínicas , Humanos , Hipoxia Encefálica/diagnóstico , Hipoxia Encefálica/etiología , Hipoxia Encefálica/terapia , Paro Cardíaco Extrahospitalario/complicaciones , Paro Cardíaco Extrahospitalario/terapia , Valor Predictivo de las Pruebas , PronósticoAsunto(s)
Regulación de la Temperatura Corporal , Paro Cardíaco/terapia , Hipotermia Inducida/métodos , Anticonvulsivantes/farmacocinética , Anticonvulsivantes/uso terapéutico , Biomarcadores/sangre , Glucemia/metabolismo , Toma de Decisiones Clínicas , Paro Cardíaco/sangre , Paro Cardíaco/fisiopatología , Humanos , Hipotermia Inducida/efectos adversos , Factores de Riesgo , Convulsiones/etiología , Convulsiones/fisiopatología , Convulsiones/prevención & control , Factores de Tiempo , Resultado del TratamientoAsunto(s)
Asfixia/complicaciones , Regulación de la Temperatura Corporal , Paro Cardíaco/terapia , Hipnóticos y Sedantes/administración & dosificación , Hipotermia Inducida/métodos , Midazolam/administración & dosificación , Propofol/administración & dosificación , Investigación Biomédica Traslacional , Animales , Asfixia/fisiopatología , Reanimación Cardiopulmonar , Paro Cardíaco/diagnóstico , Paro Cardíaco/etiología , Paro Cardíaco/fisiopatología , Humanos , Hipnóticos y Sedantes/efectos adversos , Hipnóticos y Sedantes/farmacocinética , Hipotermia Inducida/efectos adversos , Midazolam/efectos adversos , Midazolam/farmacocinética , Propofol/efectos adversos , Propofol/farmacocinética , Recalentamiento , Factores de Riesgo , Factores de Tiempo , Resultado del TratamientoRESUMEN
BACKGROUND: Critically ill patients are at marked risk of hospital-acquired infections, which increase patients' morbidity and mortality. Registered nurses are the main health care providers of physical care, including hygiene to reduce and prevent hospital-acquired infections, for hospitalized critically ill patients. OBJECTIVE: To investigate a new patient hand hygiene protocol designed to reduce hospital-acquired infection rates and improve nurses' hand-washing compliance in an intensive care unit. METHODS: A preexperimental study design was used to compare 12-month rates of 2 common hospital-acquired infections, central catheter-associated bloodstream infection and catheter-associated urinary tract infection, and nurses' hand-washing compliance measured before and during use of the protocol. RESULTS: Reductions in 12-month infection rates were reported for both types of infections, but neither reduction was statistically significant. Mean 12-month nurse hand-washing compliance also improved, but not significantly. CONCLUSIONS: A hand hygiene protocol for patients in the intensive care unit was associated with reductions in hospital-acquired infections and improvements in nurses' hand-washing compliance. Prevention of such infections requires continuous quality improvement efforts to monitor lasting effectiveness as well as investigation of strategies to eliminate these infections.
