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1.
IEEE Trans Biomed Circuits Syst ; 17(5): 900-915, 2023 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-37204964

RESUMEN

We present a wirelessly powered ultraviolet-C (UVC) radiation-based disinfecting bandage for sterilization and treatment in chronic wound care and management. The bandage contains embedded low-power UV light-emitting diodes (LEDs) in the 265 to 285 nm range with the light emission controlled via a microcontroller. An inductive coil is seamlessly concealed in the fabric bandage and coupled with a rectifier circuit to enable 6.78 MHz wireless power transfer (WPT). The maximum WPT efficiency of the coils is 83% in free space and 75% on the body at a coupling distance of 4.5 cm. Measurements show that the UVC LEDs are emitting radiant power of about 0.6 mW and 6.8 mW with and without fabric bandage, respectively, when wirelessly powered. The ability of the bandage to inactivate microorganisms was examined in a laboratory which shows that the system can effectively eradicate Gram-negative bacteria, Pseudoalteromonas sp. D41 strain, on surfaces in six hours. The proposed smart bandage system is low-cost, battery-free, flexible and can be easily mounted on the human body and, therefore, shows great promise for the treatment of persistent infections in chronic wound care.


Asunto(s)
Vendajes , Heridas y Lesiones , Humanos , Heridas y Lesiones/terapia , Rayos Ultravioleta , Tecnología Inalámbrica , Desinfección
2.
Sensors (Basel) ; 22(1)2022 Jan 05.
Artículo en Inglés | MEDLINE | ID: mdl-35009932

RESUMEN

The reliability of rolling element bearings has been substantially undermined by the presence of parasitic and stray currents. Electrical discharges can occur between the raceway and the rolling elements and it has been previously shown that these discharges at relatively high current density levels can result in fluting and corrugation damages. Recent publications have shown that for a bearing operating at specific mechanical conditions (load, temperature, speed, and slip), electrical discharges at low current densities (<1 mA/mm2) may substantially reduce bearing life due to the formation of white etching cracks (WECs) in bearing components, often in junction with lubricants. To date, limited studies have been conducted to understand the electrical discharges at relatively low current densities (<1 mA/mm2), partially due to the lack of robust techniques for in-situ quantification of discharges. This study, using voltage measurement and electrostatic sensors, investigates discharges in an oil-lubricated steel-steel rolling contact on a TE74 twin-roller machine under a wide range of electrical and mechanical conditions. The results show that the discharges events between the rollers are influenced by temperature, load, and speed due to changes in the lubricant film thickness and contact area, and the sensors are effective in detecting, characterizing and quantifying the discharges. Hence, these sensors can be effectively used to study the influence of discharges on WEC formation.

3.
Sci Rep ; 11(1): 23017, 2021 11 26.
Artículo en Inglés | MEDLINE | ID: mdl-34837021

RESUMEN

A key task of emergency departments is to promptly identify patients who require hospital admission. Early identification ensures patient safety and aids organisational planning. Supervised machine learning algorithms can use data describing historical episodes to make ahead-of-time predictions of clinical outcomes. Despite this, clinical settings are dynamic environments and the underlying data distributions characterising episodes can change with time (data drift), and so can the relationship between episode characteristics and associated clinical outcomes (concept drift). Practically this means deployed algorithms must be monitored to ensure their safety. We demonstrate how explainable machine learning can be used to monitor data drift, using the COVID-19 pandemic as a severe example. We present a machine learning classifier trained using (pre-COVID-19) data, to identify patients at high risk of admission during an emergency department attendance. We then evaluate our model's performance on attendances occurring pre-pandemic (AUROC of 0.856 with 95%CI [0.852, 0.859]) and during the COVID-19 pandemic (AUROC of 0.826 with 95%CI [0.814, 0.837]). We demonstrate two benefits of explainable machine learning (SHAP) for models deployed in healthcare settings: (1) By tracking the variation in a feature's SHAP value relative to its global importance, a complimentary measure of data drift is found which highlights the need to retrain a predictive model. (2) By observing the relative changes in feature importance emergent health risks can be identified.


Asunto(s)
COVID-19 , Hospitalización , Humanos , Aprendizaje Automático , Pandemias
4.
Sensors (Basel) ; 21(22)2021 Nov 20.
Artículo en Inglés | MEDLINE | ID: mdl-34833816

RESUMEN

This work presents a novel type of actuator that improves over the standard cantilever by permitting daisy-chaining while minimising stress to the joint connecting to the load. A detailed structural and functional comparison of the proposed device against the cantilever actuator as a baseline is given, led by a brief revision of the cantilever actuator as the state-of-the-art that highlights its limitations with respect to daisy-chaining and the stress it inherently creates within the joint connecting to the load when attempting out-of-plane displacement without rotation. Simulations of both devices' performance confirm that the newly proposed device yields the targeted displacement profile that both enables the daisy-chaining of such a device into a higher-order actuator for increased displacement and reduce stress in the joint with the load. This comes at the cost of reduced maximum displacement compared to the cantilever, which can be overcome by daisy-chaining. The proposed device's performance is further evaluated on the basis of manufactured prototypes measured by means of a laser scanning vibrometer. The prototype was manufactured on a 150 µm alumina substrate, and both electrodes and piezoelectric layer were deposited in a thick-film printing process.


Asunto(s)
Electrodos
5.
Annu Int Conf IEEE Eng Med Biol Soc ; 2015: 8018-21, 2015 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-26738153

RESUMEN

This paper highlights the potential of using prosthetic devices to sense surface textures; an important characteristic of a lower arm that is often neglected. An artificial finger equipped with a piezoelectric sensor, mounted on a fingertip, has been designed to detect surface textures of different dimensions. Signal frequencies generated during the exploratory movement of the artificial finger reliably correlate to all the widths of grooves and ridges of the surface textures under investigation. This capability provides a positive outlook in recreating a touch sensation that has been previously lost from natural fingers and palms.


Asunto(s)
Dedos , Humanos , Prótesis e Implantes , Tacto
6.
Langmuir ; 28(22): 8296-9, 2012 Jun 05.
Artículo en Inglés | MEDLINE | ID: mdl-22582838

RESUMEN

We report the synthesis of highly crystallographically textured films of stoichiometric bismuth telluride (Bi(2)Te(3)) in the presence of a surfactant, sodium lignosulfonate (SL), that resulted in the improved alignment of films in the (110) plane and offered good control over the morphology and roughness of the electrodeposited films. SL concentrations in the range 60-80 mg dm(-3) at a deposition potential of -0.1 V vs SCE (saturated calomel electrode) were found to yield the most improved crystallinity and similar or superior thermoelectric properties compared with results reported in the literature.

7.
Langmuir ; 26(22): 16980-5, 2010 Nov 16.
Artículo en Inglés | MEDLINE | ID: mdl-20923228

RESUMEN

High-quality films of bismuth antimony telluride were synthesized by electrodeposition from nitric acid electroplating baths. The influence of a surfactant, sodium ligninsulfonate, on the structure, morphology, stoichiometry, and homogeneity of the deposited films has been investigated. It was found that addition of this particular surfactant significantly improved the microstructural properties as well as homogeneity of the films with a significant improvement in the thermoelectric properties over those deposited in the absence of surfactant. A detailed microprobe analysis of the deposited films yielded a stoichiometric composition of Bi(0.35)Sb(1.33)Te(3) for the films electrodeposited in the absence of surfactant and a stoichiometry of Bi(0.32)Sb(1.33)Te(3) for films deposited in the presence of surfactant.

8.
Phys Chem Chem Phys ; 11(18): 3584-90, 2009 May 14.
Artículo en Inglés | MEDLINE | ID: mdl-19421565

RESUMEN

High density p-type Bi0.5Sb1.5Te3 nanowire arrays are produced by a combination of electrodeposition and ion-track lithography technology. Initially, the electrodeposition of p-type Bi0.5Sb1.5Te3 films is investigated to find out the optimal conditions for the deposition of nanowires. Polyimide-based Kapton foils are chosen as a polymer for ion track irradiation and nanotemplating Bi0.5Sb1.5Te3 nanowires. The obtained nanowires have average diameters of 80 nm and lengths of 20 microm, which are equivalent to the pore size and thickness of Kapton foils. The nanowires exhibit a preferential orientation along the {110} plane with a composition of 11.26 at.% Bi, 26.23 at.% Sb, and 62.51 at.% Te. Temperature dependence studies of the electrical resistance show the semiconducting nature of the nanowires with a negative temperature coefficient of resistance and band gap energy of 0.089+/-0.006 eV.

9.
Int J Surg ; 5(6): 436-40, 2007 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-18078684

RESUMEN

The surgeon Ambroise Paré designed an anthropomorphic hand for wounded soldiers in the 16th century. Since that time, there have been advances in technology through the use of computer-aided design, modern materials, electronic controllers and sensors to realise artificial hands which have good functionality and reliability. Data from touch, object slip, finger position and temperature sensors, mounted in the fingers and on the palm, can be used in feedback loops to automatically hold objects. A study of the natural neuromuscular systems reveals a complexity which can only in part be realised today with technology. Highlights of the parallels and differences between natural and artificial hands are discussed with reference to the Southampton Hand. The anatomical structure of parts of the natural systems can be made artificially such as the antagonist muscles using tendons. Theses solutions look promising as they are based on the natural form but in practice lack the desired physical specification. However, concepts of the lower spinal loops can be mimicked in principle. Some future devices will require greater skills from the surgeon to create the interface between the natural system and an artificial device. Such developments may offer a more natural control with ease of use for the limb deficient person.


Asunto(s)
Miembros Artificiales , Mano , Sistema Nervioso , Diseño de Prótesis , Humanos , Reconocimiento de Normas Patrones Automatizadas
10.
Artículo en Inglés | MEDLINE | ID: mdl-17186928

RESUMEN

Research into surface acoustic wave (SAW) devices began in the early 1970s and led to the development of high performance, small size, and high reproducibility devices. Much research has now been done on the application of such devices to consumer electronics, process monitoring, and communication systems. The use of novel materials, such as gallium phosphate (GaPO4), extends the operating temperature of the elements. SAW devices based on this material operating at 434 MHz and up 800 degrees C, can be used for passive wireless sensor applications. Interdigital transducer (IDT) devices with platinum/zirconium metallization and 1.4 microm finger-gap ratio of 1:1 have been fabricated using direct write e-beam lithography and a lift-off process. The performance and long-term stability of these devices has been studied, and the results are reported in this paper.


Asunto(s)
Acústica/instrumentación , Galio/química , Microondas , Fosfatos/química , Diseño Asistido por Computadora , Impedancia Eléctrica , Diseño de Equipo , Análisis de Falla de Equipo , Galio/efectos de la radiación , Ensayo de Materiales , Fosfatos/efectos de la radiación , Propiedades de Superficie
11.
Artículo en Inglés | MEDLINE | ID: mdl-15742558

RESUMEN

This paper details improvements of the d33 co-efficient for thick-film lead zirconate titanate (PZT) layers. In particular, the effect of blending ball and attritor milled powders has been investigated. Mathematical modeling of the film structure has produced initial experimental values for powder combination percentages. A range of paste formulations between 8:1 and 2:1 ball to attritor milled PZT powders by weight have been mixed into a screen-printable paste. Each paste contains 10% by weight of lead borosilicate glass and an appropriate quantity of solvent to formulate a screen printable thixotropic paste. A d33 of 63.5 pC/N was obtained with a combination of 4:1 ball milled to attritor milled powder by weight. The improved paste combines the high d33 values of ball and the consistency of attritor milled powder. The measured d33 coefficient was further improved to 131 pC/N by increasing the furnace firing profile to 1000 degrees C, increasing the poling temperature to 200 degrees C, and using gold cermet and polymer electrodes that avoid silver migration effects and repeated firing of the PZT film.

12.
Development ; 130(16): 3715-24, 2003 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-12835388

RESUMEN

EGF receptor signalling plays diverse inductive roles during development. To achieve this, its activity must be carefully regulated in a variety of ways to control the time, pattern, intensity and duration of signalling. We show that the cell surface protein Echinoid is required to moderate Egfr signalling during R8 photoreceptor selection by the proneural gene atonal during Drosophila eye development. In echinoid mutants, Egfr signalling is increased during R8 formation, and this causes isolated R8 cells to be replaced by groups of two or three cells. This mutant phenotype resembles the normal inductive function of Egfr in other developmental contexts, particularly during atonal-controlled neural recruitment of chordotonal sense organ precursors. We suggest that echinoid acts to prevent a similar inductive outcome of Egfr signalling during R8 selection.


Asunto(s)
Moléculas de Adhesión Celular/metabolismo , Proteínas de Drosophila/metabolismo , Drosophila melanogaster/crecimiento & desarrollo , Receptores ErbB/metabolismo , Neuronas/fisiología , Proteínas Represoras/metabolismo , Transducción de Señal/fisiología , Animales , Factores de Transcripción con Motivo Hélice-Asa-Hélice Básico , Moléculas de Adhesión Celular/genética , Proteínas de Unión al ADN/genética , Proteínas de Unión al ADN/metabolismo , Proteínas de Drosophila/genética , Genes Reporteros , Morfogénesis , Mutación , Proteínas del Tejido Nervioso , Neuronas/citología , Fenotipo , Células Fotorreceptoras de Invertebrados/crecimiento & desarrollo , Células Fotorreceptoras de Invertebrados/metabolismo , Células Fotorreceptoras de Invertebrados/ultraestructura , Proteínas Recombinantes de Fusión/metabolismo , Proteínas Represoras/genética
13.
Artículo en Inglés | MEDLINE | ID: mdl-11885673

RESUMEN

This paper describes a new multi-degree-of-freedom (MDOF) ultrasonic motor that comprises few parts and is based on low-cost thick-film technology. Conventional ultrasonic motors using bulk lead zirconate titanate (PZT) or thin-film PZT layers are relatively expensive at the present time. Thick-film printed PZT technology provides the opportunity to reduce the costs of ultrasonic motors. To demonstrate the feasibility of this approach, an ultrasonic motor was fabricated from alumina using thick-film printed PZT actuators. The thick-film PZT and electrode layers were printed on a thin alumina plate, and a tiny cylinder was mounted at its center. This cylinder magnifies the lateral displacement of the stator, holds the spherical rotor, and transmits the driving force to the sphere. Three bending vibrations, B22, B30, B03, of the plate were applied to rotate the sphere. Sufficient displacements for rotating the sphere were obtained near the resonance of B22 by applying an excitation voltage of 200 V peak-to-peak via a three-phase drive circuit. Rotations in three orthogonal directions have been observed by controlling the phase of the driving signal to the PZT electrodes, and a MDOF ultrasonic motor was successfully realized.

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