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1.
Acta Otorhinolaryngol Ital ; 44(2): 120-127, 2024 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-38420840

RESUMEN

Objective: The involvement of the inner ear in otosclerosis may lead to the development of cochlear otosclerosis. The aim of this study was to analyse changes in the chemical composition and microstructure of the stapes in the course of otosclerosis compared to healthy stapes. Materials and methods: This analysis included 31 patients with otosclerosis and 9 patients without otosclerosis. Microanalytical and diffraction techniques were used to assess the elemental distribution and orientation topography of the stapes. Results: The concentration of Ca2+ in the study group was significantly lower in the area of the anterior crus of the stapes than in the posterior crus. A reduction in the Ca2+/P3+ ratio in the anterior crus was associated with deteriorated bone conduction and tinnitus. Degradation of the stapes microstructure in the area of otosclerotic lesions was observed with scanning electron microscopy. Conclusions: Bone remodelling is most significant at the closest location to typical otosclerotic lesions with hydroxyapatite porosity and scale-like bone formation according to scanning electron microscopy. There is a relationship between the disturbance of calcium metabolism and the development of clinical symptoms of cochlear otosclerosis.

2.
Med Sci Monit ; 29: e939679, 2023 Jun 20.
Artículo en Inglés | MEDLINE | ID: mdl-37337421

RESUMEN

BACKGROUND Otosclerosis is a pathology that interferes with the conduction of vibrations to the inner ear, triggering changes in the auditory ossicles and their associated joints due to mechanical overload. This study primarily aims to evaluate these overload-induced modifications in the stapes head resulting from the immobilization of the base of the third auditory ossicle in otosclerosis patients. MATERIAL AND METHODS We conducted a comparative analysis of patients undergoing their first surgery for otosclerosis. The test group consisted of 31 patients who underwent stapedotomy between 2020-2021. For comparison, we utilized a control group comprising stapes samples extracted during vestibular schwannoma surgeries via a transcochlear approach. A prospective analysis of bone tissue surface topography and chemical composition was executed using scanning electron microscopy (SEM). RESULTS SEM analysis of the stapes head in otosclerosis patients relative to the control group displayed no significant differences in chemical composition or the presence of otosclerotic foci. Nonetheless, various forms of bone tissue surface damage were noted on the stapes head in all otosclerosis patients. Mild changes were evident in 90% of the samples, while small linear bone tissue fractures were observed in 58% of the samples. Furthermore, minor osteophytic changes were detected in 16% of the samples. CONCLUSIONS The immobilization of the stapes base by otosclerotic foci instigates overloads in the incus-stapes joint, leading to the eventual remodeling of the stapes head articular surface.


Asunto(s)
Otosclerosis , Cirugía del Estribo , Humanos , Estribo , Otosclerosis/patología , Otosclerosis/cirugía , Microscopía Electrónica de Rastreo , Osículos del Oído/patología , Huesos/patología
3.
Ear Nose Throat J ; : 1455613231167243, 2023 Apr 12.
Artículo en Inglés | MEDLINE | ID: mdl-37046387

RESUMEN

OBJECTIVE: The assessment of bone conduction thresholds in patients with conductive hearing loss is not a full measure of the function of the inner ear due to the weakening of the influence of middle ear components on bone conduction. This relationship has been called the 'Carhart effect'. METHODS: The retrospective analysis covered 977 patients diagnosed and treated for middle ear diseases from 2010 to 2020. The Carhart effect was considered to be an increase in the bone conduction threshold by a minimum of 10 dB relative to adjacent frequencies. The study was performed with the aim of assessing the presence of the Carhart effect in the course of middle ear diseases in pretreatment analysis. RESULTS: The Carhart effect was observed in 532 cases, most often in patients with chronic otitis media and otosclerosis. It was least often observed in patients with otitis media with effusion. In otitis media with effusion, the Carhart effect was more often noted for the frequency of 4000 Hz, in otosclerosis for the frequency of 2000 Hz. In patients with chronic otitis media, this effect for the frequency of 4000 Hz was correlated with the location of inflammatory changes in the attic area. The presence of inflammatory lesions in the oval window area was associated with the presence of the Carhart effect for the frequency of 2000 Hz. CONCLUSIONS: 1. The frequency of the Carhart effect observed in diseases of the middle ear does not depend on the disease entity but on the type and location of abnormalities in the middle ear. 2. The Carhart effect observed for the frequency of 4000 Hz coexists with the localization of lesions in the range of the malleus and incus, and for the frequency of 2000 Hz, it is partially associated with abnormalities in the range of stapes and oval window.

4.
Otolaryngol Pol ; 77(2): 1-5, 2023 Feb 20.
Artículo en Inglés | MEDLINE | ID: mdl-36806470

RESUMEN

BackgroundThe Eustachian tube is a complex and inaccessible structure, which is responsible for the ventilation of the middle ear. The aim of the study was the assessment of an impact of chronic sinusitis on the auditory tube function. MethodsThe prospective analysis of 84 surgically treated chronic sinusitis patients was carried out. This study is based on preoperative results of impedance audiometry in correlation with the data from the medical history of chronic sinusitis, symptoms reported by the patients, results of Computered Tomography (CT) and the stage of inflammatory changes according to Lund and Mackay score. ResultsThe significant majority of patients of our study (65) had advanced auditory tube symptoms, while 4 patients suffered from symptoms significantly impacting daily life. In patients with chronic sinusitis the analysis demonstrated that tympanometry type B (12.67) and C (12.4) occured with significantly higher number of points of Lund-Mackay score than type A (9.2). In allergy sufferers type B of tympanometry was more often observed with characteristically bilaterally located inflammatory changes in maxillary and anterior ethmoid sinuses.ConclusionThe profile of chronic sinusitis patient in whom Eustachian Tube Dysfunction is more often observed, is as follows: Lund and Mackay score above 12pathological changes are bilaterally observed in maxillary and frontal ethmoid sinuses decrease of nasal patency nad postnasal dripAllergyoverusing alcohol and cigarettes, at least alcoholWorse result of Lund and Mackay score and the age of patients are 2 factors favoring the dysfunction of the Eustachian Tube.


Asunto(s)
Trompa Auditiva , Sinusitis , Humanos , Oído Medio , Pruebas de Impedancia Acústica , Enfermedad Crónica , Sinusitis/diagnóstico por imagen , Sinusitis/cirugía
5.
Med Sci Monit ; 29: e939255, 2023 Jan 28.
Artículo en Inglés | MEDLINE | ID: mdl-36707983

RESUMEN

BACKGROUND A Carhart notch in the pure tone audiogram can be an indicator of stapes fixation in otosclerosis. This retrospective study of 157 patients with otosclerosis aimed to evaluate the association between the presence of a Carhart notch on the preoperative bone-conduction audiogram and postoperative hearing and balance evaluated by the Vestibular Disorders Activities of Daily Living scale. MATERIAL AND METHODS Patients with suspected otosclerosis based on medical history and audiometric tests were considered. The analysis included 157 consecutive patients who underwent surgery in the years 2016 to 2019, in whom the diagnosis of otosclerosis was confirmed during surgery. Carhart notch was defined as an impairment in the bone conduction threshold of ≥7.5 dB for 2000 Hz frequencies above the mean thresholds at higher and lower adjacent frequencies. The Vestibular Disorders Activities of Daily Living subjective scale was used in the preoperative period and 4 and 12 months after surgery. RESULTS The preoperative presence of Carhart notch and progressive sensorineural hearing loss were statistically significantly correlated with more common onset of tinnitus and then dizziness (P=0.006). Preoperative vertigo was observed in patients who had Carhart notch observed in the preoperative audiometric test. This vertigo more commonly coexisted with profound sensorineural hearing loss and minor or no improvement in average values of bone conduction after surgery (P=0.002). CONCLUSIONS Preoperative Carhart notch on audiogram and the severity of sensorineural hearing loss were associated with tinnitus and vertigo. However, preoperative Carhart notch was not associated with persistent postoperative tinnitus in patients with cochlear otosclerosis.


Asunto(s)
Pérdida Auditiva Sensorineural , Otosclerosis , Cirugía del Estribo , Acúfeno , Humanos , Otosclerosis/cirugía , Otosclerosis/complicaciones , Otosclerosis/diagnóstico , Estudios Retrospectivos , Actividades Cotidianas , Cirugía del Estribo/métodos , Conducción Ósea , Pérdida Auditiva Sensorineural/cirugía , Vértigo , Resultado del Tratamiento , Audiometría de Tonos Puros
6.
Ear Nose Throat J ; 102(11): 709-714, 2023 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-34176331

RESUMEN

OBJECTIVE: During the postoperative period, most patients with otosclerosis report vertigo and/or nausea caused by interventions within the inner ear. The aim of this study was to evaluate both early and late vertigo associated with hearing improvement after stapes surgery for otosclerosis. METHODS: The analysis included 170 patients admitted to the hospital undergoing their first surgery for otosclerosis. Audiological diagnostics, surgical techniques, and symptoms reported by the patients were all analyzed. RESULTS: A statistical correlation and an unfavorable influence of late, undesired symptoms, such as vertigo, nausea/vomiting, and nystagmus, on final hearing improvement after surgical treatment of otosclerosis were found. Prostheses that were too long or placed too deep within the inner ear space were the most frequent cause of both vertigo and lack of hearing improvement observed after stapedotomy. CONCLUSIONS: A significant negative influence on bone conduction thresholds, particularly at 2000 Hz, was associated with vestibular symptoms persisting for 7 days after the surgery. Symptoms of impaired bony labyrinth function after stapedotomy, persisting for more than 1 year, were associated with insufficient reduction of the air-bone gap and worse improvement in bone conduction thresholds at 1000 and 2000 Hz. The cause of both problems was related to a prosthesis that was too long or placed too deep in the inner ear during stapedotomy.


Asunto(s)
Otosclerosis , Cirugía del Estribo , Humanos , Otosclerosis/complicaciones , Otosclerosis/cirugía , Audición , Cirugía del Estribo/efectos adversos , Cirugía del Estribo/métodos , Conducción Ósea , Vértigo/complicaciones , Náusea , Resultado del Tratamiento , Estudios Retrospectivos , Estribo
7.
Ear Nose Throat J ; 101(7): 474-478, 2022 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-35916230

RESUMEN

BACKGROUND: Otosclerosis is a disease of the osseous labyrinth. The disease causes 5% to 9% of all cases of hearing loss and 18% to 22% of conductive hearing loss. The treatment of choice is a surgery. The hearing improvement after the operation is determined by various factors. AIMS/OBJECTIVES: The aim of the analysis is to determinate changes in hearing after stapedoplasty in view of surgery side in the patients operated on otosclerosis by right-handed surgeons. MATERIAL AND METHODS: The analysis involved patients hospitalized and operated on otosclerosis between 2012 and 2018. Only patients with their first middle ear surgery due to otosclerosis were included in the study. The patients were operated by 2 right-handed surgeons who used the same surgical technique and had similar experience in otosclerosis surgery. The study included patients who were divided into 2 groups: with self-tightening prosthesis and with manually tightening prosthesis. RESULTS: The procedure performed by right-handed operators on the left side using prostheses requiring manual fixation on the incus was associated with poorer audiometric results compared to the results of surgeries on the right side. In patients with the self-tightening prostheses, the audiometric improvement of hearing was bilaterally comparable independently from operation side. CONCLUSION: (1) The dependence of hearing improvement on the surgery side was demonstrated in cases of surgeries performed on the left ear by right-handed surgeons, particularly with manually tightening prosthesis. (2) Self-tightening prostheses in stapedotomy limit the human factor, reducing the risk of complications after otosclerosis surgery and provide repeatable hearing improvement.


Asunto(s)
Prótesis Osicular , Otosclerosis , Cirugía del Estribo , Cirujanos , Conducción Ósea , Audición , Humanos , Otosclerosis/complicaciones , Otosclerosis/cirugía , Estudios Retrospectivos , Cirugía del Estribo/métodos
8.
Otolaryngol Pol ; 76(3): 1-6, 2022 Apr 14.
Artículo en Inglés | MEDLINE | ID: mdl-35796394

RESUMEN

<b>Introduction:</b> Otosclerosis is a disease that occurs only in humans, in the course of which there are foci of pathological ossification in the temporal bone. The etiology of the dise ase is not fully understood. Treatment of the conductive component of hearing loss is surgical. The results of the treatment are influenced by factors related to the surgery, the local condition of the middle ear and the function of the inner ear. </br></br> <b>Aim:</b> The aim of the study is to identify factors influencing the improvement of hearing in patients treated surgically due to otosclerosis. </br></br> <b>Material and methods:</b> The study included patients who underwent otosclerosis for the first middle ear surgery and under-went stapedotomy. Considering the factors that may affect the outcome of surgical treatment, the patients qualified for the analysis were divided into subgroups. All patients underwent a medical history and physical examination of otorhinolaryn-gology and a complete set of audiological examinations. </br></br> <b> Results:</b> A statistically significant reduction in cochlear reserve was observed in all patients after stapedotomy. The be-neficial effect of the performed treatment on the improvement of threshold values of bone conduction in patients with mild sensorineural hearing loss was also confirmed. Intraoperative removal of adhesions present in the tympanic cavity significantly improved hearing in terms of bone conduction values, especially at 500 Hz. </br></br> <b> Conclusions:</b> (1) The conducted study confirmed the influence of factors related to the local condition of the middle ear lining on the final result of otosclerosis surgery; (2) Audiometric markers of cochlear otosclerosis, observed before surgical treat-ment, are an unfavorable factor in the improvement of hearing after the performed treatment.


Asunto(s)
Otosclerosis , Cirugía del Estribo , Conducción Ósea , Audición , Pruebas Auditivas , Humanos , Otosclerosis/cirugía , Cirugía del Estribo/métodos
9.
Ear Nose Throat J ; : 1455613211043685, 2021 Oct 11.
Artículo en Inglés | MEDLINE | ID: mdl-34633243

RESUMEN

Objective: The presence of Carhart's notch at 2000 Hz in otosclerosis links the changed bone conduction for this frequency with the otosclerotic process occurring in the oval window. The aim of this study is to perform an audiometric assessment of the effectiveness of surgical treatment of otosclerosis depending on the incidence of Carhart's notch. Methods: The analysis included 116 patients treated surgically for the first time due to otosclerosis. Patients were divided into 4 groups depending on the occurrence of Carhart's notch, determined by pure-tone audiometry (PTA) before the surgery and 36 months afterward. The mean value of bone conduction thresholds was calculated for 500 Hz, 1000 Hz, 2000 Hz, and 3000 Hz in the groups in which the Cahart's notch was observed. This value of bone conduction (BC) was a reference point for further analysis in patients who had no preoperative or postoperative Carhart's notch. Results: The analysis indicated that Cahart's notch in preoperative PTA is a statistically significant improvement factor for average BC. It was found that over a longer observation period, the presence of Carhart's notch has adverse effects on the size of the postoperative air-bone gap, and consequently on hearing improvement after surgical treatment. A comparison between patients from the two groups without preoperative Carhart's notch found that no beneficial effects of the surgery on speech comprehension were observed regarding high-level sensorineural hearing loss (SNHL). Conclusions: (1) In a long-term observation post-stapedotomy, average BC values were found to improve. Nevertheless, the improvement is less evident in patients with preoperative Carhart's notch. (2) Disappearance of Cahart's notch after surgical treatment of otosclerosis is a good prognosis of improvement in speech audiometry. (3) Deep SNHL in the absence of Carhart's notch in PTA constitutes a bad prognostic factor for improvement in speech audiometry in patients qualified for surgical treatment of otosclerosis.

10.
Acta Otorhinolaryngol Ital ; 41(4): 371-376, 2021 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-34533541

RESUMEN

OBJECTIVE: The damaging effect of cholesteatomas presents mainly as bone resorption by osteoclasts located in the space between the bone and perimatrix. This process is initiated by the molecular cascade of osteoclast differentiation factors. The aim of the study is to analyse cholesteatoma microstructures via scanning electron microscope (SEM), and associate them with risk and grade of bone erosion. METHODS: Pathological middle ear tissue fragments with cholesteatoma visible under a microscope were collected from 58 patients operated on for chronic otitis media with features of bone defects in the middle ear walls. These fragments were examined under a scanning electron microscope. RESULTS: Analysis of the cholesteatomas' surface under a SEM revealed both regular and irregular structure of the matrix, most being the latter. Irregular matrix structures were observed in cases with a short disease history and in patients for whom this was the first surgical procedure. In our analysis, a cholesteatoma matrix with regular structures was associated with less bone destruction of the middle ear space. CONCLUSIONS: The microstructure of cholesteatomas that showed regular layers under SEM coincides with reduced destruction of the middle ear bone walls. An irregular structure (pathognomonic for a process with a short medical history, and in patients operated on for the first time) is characterised by a tendency towards deeper destruction of bone tissue.


Asunto(s)
Resorción Ósea , Colesteatoma del Oído Medio , Humanos , Microscopía Electrónica de Rastreo , Osteoclastos , Factores de Riesgo
11.
Otolaryngol Pol ; 75(3): 1-5, 2021 Feb 02.
Artículo en Inglés | MEDLINE | ID: mdl-33949967

RESUMEN

Objectives Chronic purulent cholesteatoma of the middle ear, as well as to a lesser extent chronic granulomatous otitis media, lead to destruction of bone structures within the middle ear space. Above process is controlled by the OPG/RANKL/RANK system. Material and methods An analysis of 140 patients operated on due to chronic otitis media was performed. For the detailed analysis in the scanning electron microscope, 40 patients were selected who had been diagnosed with chronic cholesteatoma of the middle ear and chronic granulomatous otitis media. Finally the study in SEM included 20 patients. Results The regular structure of cholesteatoma depicted in the Scanning Electron Microscope concerned 5 patients with diagnosed. In the remaining 7 patients, the system was irregular and even chaotic. Lack of regularity can also be observed in the case of granulation tissue, which in the SEM image presented itself as an irregular tissue mass without detectable regularities. Conclusions 1. Regular pattern of the cholesteatoma matrix cells observed in some patients with chronic cholesteatoma of the middle ear reduces the molecular permeability of inflammatory cytokines, concurrently limiting the destructive activity on bone structures. 2. The presence of inflammatory granulation tissue in the middle ear is accompanied by an influx of leukocytes: neutrophils and lymphocytes, which are the source of pro-inflammatory cytokines, the growth of which activates the processes leading to the damage of bone tissue and the development of inflammation. 3. No specimen of acquired cholesteatoma revealed presence of commensalism like organism on the surface of exfoliated human epithelium of Demodex species.


Asunto(s)
Colesteatoma del Oído Medio , Otitis Media Supurativa , Otitis Media , Colesteatoma del Oído Medio/complicaciones , Colesteatoma del Oído Medio/cirugía , Enfermedad Crónica , Oído Medio , Humanos , Microscopía Electrónica de Rastreo , Otitis Media Supurativa/complicaciones
12.
Ear Nose Throat J ; 100(10): NP438-NP443, 2021 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-32397813

RESUMEN

BACKGROUND: Despite different etiologies, chronic otitis media involves the damaging and restructuring of bone tissue. The inflammatory process destroys elements of the ossicular chain, and bone lesions may appear that allow the development of otogenous complications. AIMS/OBJECTIVES: A correlation between the degree of damage to the ossicular chain as well as the bony walls of the middle ear and the type of chronic inflammatory lesions was sought. Destructive changes to bones were observed using scanning microscopy. MATERIAL AND METHODS: The removed damaged fragments of the ossicles were prepared for evaluation with a scanning microscope. Preparations were sputter-coated with a thin layer of gold and subsequently evaluated. RESULTS: Of 220 surgeries carried out in the discussed period, destruction of the middle ear bone walls, opening the way for the development of intracranial complications, was found in 27 patients. Most of them had ongoing chronic otitis media with granulation. CONCLUSIONS: (1) Bone loss of the skull base was observed more frequently in patients with chronic otitis media with granulation than with cholesteatoma. (2) In chronic otitis media with cholesteatoma, damage to the ossicular chain was observed significantly more frequently than in the case of otitis media with granulation.


Asunto(s)
Osículos del Oído/ultraestructura , Oído Medio/ultraestructura , Otitis Media/patología , Adulto , Anciano , Colesteatoma del Oído Medio/complicaciones , Colesteatoma del Oído Medio/patología , Enfermedad Crónica , Osículos del Oído/patología , Osículos del Oído/cirugía , Oído Medio/patología , Femenino , Tejido de Granulación/patología , Humanos , Masculino , Microscopía Electrónica de Rastreo , Persona de Mediana Edad , Otitis Media/complicaciones , Estudios Prospectivos , Base del Cráneo/patología
13.
Ear Nose Throat J ; 100(4): NP193-NP197, 2021 May.
Artículo en Inglés | MEDLINE | ID: mdl-31558062

RESUMEN

OBJECTIVE: Otosclerosis is an underlying disease of the bony labyrinth. This disorder, occurring only within the area of a person's temporal bone, is characterized by a progressive hearing loss and tinnitus. MATERIAL AND METHODS: The study looked for the answer to the question of whether the presence or absence of Carhart notch in the presurgical tonal audiogram affects the final outcome of the otosclerosis surgery. RESULTS: The analysis included 140 patients operated on for the first time due to otosclerosis between 2010 and 2016. The study group consisted of 107 women aged from 19 to 62 (average age: 40.33) and 33 men aged 27 to 59 (average age: 38.23). Analysis showed a statistically better result of stapedotomy in patients without the notch than in the same procedure in patients with the notch present. The opposite situation occurred in the case of stapedectomy. CONCLUSION: (1) The presence of a refraction of the bone conduction curve with a depth of 10 to 20 dB at a frequency of 2000 Hz (the so-called Carhart notch) in the presurgical tonal audiogram is an unfavorable prognostic factor in relation to closing the cochlear reserve and improving bone conduction after the stapedotomy. (2) Regardless of the presence or absence of Carhart notch in the presurgical tonal audiogram, stapedotomy is the procedure with the highest efficiency in the treatment of otosclerosis.


Asunto(s)
Audiometría de Tonos Puros/estadística & datos numéricos , Conducción Ósea/fisiología , Pérdida Auditiva/fisiopatología , Otosclerosis/fisiopatología , Cirugía del Estribo , Adulto , Femenino , Pérdida Auditiva/etiología , Pérdida Auditiva/cirugía , Humanos , Masculino , Persona de Mediana Edad , Otosclerosis/complicaciones , Otosclerosis/cirugía , Valor Predictivo de las Pruebas , Periodo Preoperatorio , Pronóstico , Acúfeno/etiología , Acúfeno/fisiopatología , Acúfeno/cirugía , Resultado del Tratamiento , Adulto Joven
14.
Ear Nose Throat J ; 100(5): NP248-NP255, 2021 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-31565971

RESUMEN

OBJECTIVE: Chronic otitis media is a heterogeneous disorder. Chronic suppurative otitis media with cholesteatoma and, to a lesser extent, chronic otitis media with granulation lead to the destruction of bone structures within the middle ear. Bone loss may appear in the prominence of the horizontal semicircular canals and the bony canal of the facial nerve. The inflammatory process may spread to the bony labyrinth of the sigmoidal sinuses and the cranial cavities. MATERIALS AND METHODS: The analysis comprised the examination of fragments of auditory ossicles removed during surgery in 21 patients with various types of chronic inflammation of the middle ear. The purpose of this study was to evaluate the usefulness of scanning electron microscopy in evaluating the erosion of middle ear ossicles in different types of chronic otitis media. Images captured at various magnifications were used for the best possible illustration of the observed lesions in bone tissue. RESULTS: The observed lesions and the degree of bone surface damage were dependent on the type of chronic inflammation of the middle ear. The largest destructive changes in the ossicular chain were observed in chronic otitis media with cholesteatoma; smaller changes were observed in chronic otitis media with granulation. CONCLUSION: In the case of damage to the ossicles inflicted by inflammation, the use of a modeled bone block made of a temporal bone taken from outside the tympanic cavity or a biomaterial prosthesis is a good choice in ossiculoplasty.


Asunto(s)
Colesteatoma del Oído Medio/diagnóstico por imagen , Osículos del Oído/diagnóstico por imagen , Tejido de Granulación/diagnóstico por imagen , Microscopía Electrónica de Rastreo , Otitis Media/diagnóstico por imagen , Colesteatoma del Oído Medio/patología , Enfermedad Crónica , Osículos del Oído/patología , Oído Medio/diagnóstico por imagen , Oído Medio/patología , Tejido de Granulación/patología , Humanos , Ilustración Médica , Reemplazo Osicular/métodos , Otitis Media/patología
15.
Ann Otol Rhinol Laryngol ; 130(7): 731-737, 2021 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-33143463

RESUMEN

INTRODUCTION: Septal perforations are among the most common craniofacial defects. The causes of septal perforations are varied. OBJECTIVES: The purpose of the study was to develop a septal cartilage implant biomaterial for use in the reconstruction of nasal septal perforations and prepare personalized implants for each patient individually using 3D printing technology. METHODS: Fragments of septal nasal cartilage from 16 patients undergoing surgery for a deviated nasal septum were analyzed to establish microfeatures in individual samples. A scanning electron microscope was used to estimate the microstructure of the removed septal cartilage. 3D models of porous scaffolds were prepared, and a biomaterial was fabricated in the shape of the collected tissue using a 3D printer. RESULTS: Of the various materials used in the Fused Deposition Modeling (FDM) technology of 3D printing, PLLA was indicated as the most useful to achieve the expected implant features. The implant was designed using the indicated pre-designed shape of the scaffold, and appropriate topography, geometry and pore size were included in the design. CONCLUSIONS: The implant's structure allows the use of this device as a framework to carry nanoparticles (antibiotics or bacteriophages). It is possible to create a porous scaffold with an appropriately matched shape and a pre-designed geometry and pore size to close nasal septal perforations even in cases of large septal cartilage defects.


Asunto(s)
Materiales Biocompatibles , Perforación del Tabique Nasal/cirugía , Prótesis e Implantes , Humanos , Procedimientos Quirúrgicos Otorrinolaringológicos/métodos , Impresión Tridimensional
16.
J Int Adv Otol ; 16(3): 353-357, 2020 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-33136015

RESUMEN

OBJECTIVES: Otosclerosis is an underlying disease of the bony labyrinth that results in hearing loss. In some cases, the involvement of the bony part of the cochlea results in mixed hearing loss. The aim of this analysis was to seek a correlation between the results of speech audiometry tests and the changes in bone-conduction thresholds observed after surgical treatment. MATERIALS AND METHODS: The analysis included 140 patients who were hospitalized and surgically treated for otosclerosis. The patients who were treated with stapedotomy were divided into subgroups based on the value of the bone-conduction threshold before the surgery. An audiological assessment was performed, with pure-tone threshold audiometry and speech audiometry tests taken into account. RESULTS: The effectiveness of the surgery was judged by the change in the speech audiometry test results after 12 months of observation. After the surgery, it was found that a significant improvement, characterized as achieving 100% understanding of speech, occurred in 61.90% of the patients. CONCLUSION: There is a correlation between the improvement in speech audiometry tests and bone-conduction curve after stapedotomy. The changes achieved in the bone-conduction curve at the frequency range up to 3,000 Hz (hertz) had a significant impact on the improvements in speech audiometry test results. Higher frequencies provide more data for improving the hearing process. A mean bone-conduction threshold between 21 and 40 dB (decibels) in the pure-tone audiometry examination performed before surgery is a favorable prognostic factor in the improvement of the bone-conduction threshold after surgery.


Asunto(s)
Otosclerosis/cirugía , Cirugía del Estribo , Audiometría , Audiometría de Tonos Puros , Audiometría del Habla , Umbral Auditivo , Conducción Ósea , Humanos , Estudios Retrospectivos , Resultado del Tratamiento
17.
Otolaryngol Pol ; 74(4): 1-7, 2020 May 13.
Artículo en Inglés | MEDLINE | ID: mdl-32636350

RESUMEN

<b>Introduction: </b>Knowledge about the physiology of a healthy middle ear is essential for understanding the activity and mechanics of the ear as well as the basics of ossiculoplasty. Trauma of the epithelial lining of the tympanic cavity as well as the ossicular chain may be the result of chronic inflammation and surgery. Depending on the observed changes of the middle ear lining, there are several types of distinguished chronic inflammatory changes: simple, with cholesteatoma, with the formation of inflammatory granulation tissue, in course of specific diseases. <br><b>Purpose: </b>The aim of the article is presentation of the microstructure and vasculature of the ossicular chain in the Scanning Electron Microscope. Particular attention is drawn to the anatomical aspects of the structure and connections of auditory ossicles as vital elements for reconstruction of the conduction system of the middle ear. <br><b>Material and method: </b>The analysis covered auditory ossicles standardly removed in accordance with the methodology of the investigated surgical procedures. The preparations were evaluated in a scanning electron microscope. <br><b>Results: </b>The exposure of bone surface promotes deep erosion. The advanced process of destruction of bone surface in the case of chronic otitis media correlates with a significant degree of damage to both the lining covering the auditory ossicles and that surrounding articular surfaces. <br><b>Conclusions: </b>(1) The ossicles in the image of the Scanning Electron Microscope are covered with lining. It passes from the surface of the ossicles to the vascular bundles, forming vascular sheaths; (2) Damage to lining continuity on the surface of the auditory ossicles promotes the rapid destruction of bone tissue in the inflammatory process; (3) The dimensions of the individual ossicles are respectively: malleus - 8.36 +/- 0.01, incus - 8.14 +/- 0.0, stapes - 3.23 +/- 0.01 mm. Behavior of the anatomical length of ossicular chain during tympanoplasty appears to be essential to maintaining adequate vibration amplitude of the conductive system of the middle ear.


Asunto(s)
Osículos del Oído/diagnóstico por imagen , Osículos del Oído/patología , Oído Medio/diagnóstico por imagen , Oído Medio/patología , Microscopía Electrónica de Rastreo , Osículos del Oído/cirugía , Oído Medio/cirugía , Femenino , Humanos , Masculino , Otitis Media/diagnóstico por imagen , Otitis Media/patología , Timpanoplastia
18.
Acta Otolaryngol ; 140(7): 533-536, 2020 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-32223484

RESUMEN

Backgrounds: Otosclerosis is the cause of between 5% and 9% of all deafness cases and between 18% and 22% of conductive hearing loss cases. Neurosensory deafness develops in 30% of patients with otosclerosis.Aims/Objectives: The aim was to seek a correlation that would reflect the dependence of the results of middle ear surgery on the type of abnormalities atypical of otosclerosis but found during the stapedotomy surgery.Materials and Methods: The analysis included 140 patients who underwent surgery for otosclerosis. The hearing of all patients was assessed using an audiometric test.Results: In the assessment of changes in the mean bone conduction values, statistically significant differences between the reference group and the subgroup of patients on whom a myringoplasty was performed, as well as in patients with adhesions present in the middle ear spaces, were found only for the 500 Hz frequency.Conclusion and Significance: The removal of abnormalities, such as the loss of the eardrum (iatrogenic), changes to the lining and adhesions other than those typical of otosclerosis, restores middle ear mechanics after a stapedotomy on the inner ear and leads to a measurable improvement in mean bone conduction values.


Asunto(s)
Oído Medio/cirugía , Otosclerosis/cirugía , Cirugía del Estribo , Adulto , Conducción Ósea , Oído Medio/anomalías , Humanos , Persona de Mediana Edad , Procedimientos Quirúrgicos Otorrinolaringológicos , Pronóstico , Hueso Temporal
19.
Otolaryngol Pol ; 75(2): 15-20, 2020 Dec 07.
Artículo en Inglés | MEDLINE | ID: mdl-33949316

RESUMEN

Backgrounds Otosclerosis is an underlying disease of the bony labyrinth. The hearing loss is most often of conductive nature, in some cases the involvement of the bony part of the cochlea results in mixed hearing loss. Aims: The aim of the analysis was to answer the question whether a surgery on one of the ears affects the state of the other ear in the course of otosclerosis. Methods The analysis included 140 patients hospitalized and operated on between 2010 - 2016. Only patients who had not had a surgical operation within the middle ear due to otosclerosis prior to the study were included in it. An audiological assessment was performed with the use of pure tone threshold audiometry taking into account. Results In the group of patients with no Carhart's notch, the mean threshold of bone conduction was statistically lower than before the procedure for the frequencies of 500, 1000 Hz and statistically equal for the frequency of 2000 Hz. The same analysis in the group of patients with Carhart's notch present in the pre-surgical tonal audiogram of the non-operated ear showed a statistically significant lower value of the post-surgical threshold bone conduction value. Conclusion It was confirmed the possibility of improving the hearing of the non-operated ear after the stapedotomy of the opposite ear, in the author's own studies by an average of 5 dB in the low-frequency range.


Asunto(s)
Otosclerosis , Cirugía del Estribo , Audiometría de Tonos Puros , Umbral Auditivo , Conducción Ósea , Humanos , Otosclerosis/cirugía , Estudios Retrospectivos , Resultado del Tratamiento
20.
Otolaryngol Pol ; 74(5): 7-10, 2020 May 13.
Artículo en Inglés | MEDLINE | ID: mdl-34550093

RESUMEN

The authors propose a set of rehabilitation exercises concerning the muscles which are responsible for movement of the eyeball. After surgical treatments of retrobulbar tumors, the function of the eyeball muscles is often inadequate. Some compensation should be created at the level of the central nervous system, which means trigging adaptation, substitution and habituation. The exercises should be started just after the patient is awakened: first in the horizontal position, then sitting position and finally standing position. The highest number of exercises should be done in the direction of extreme diplopia.


Asunto(s)
Neoplasias , Órbita , Diplopía , Humanos
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