RESUMEN
BACKGROUND: The absence of the I allele of the angiotensin converting enzyme (ACE) gene has been associated with higher levels of circulating ACE, lower nitric oxide (NO) release and hypertension. The purposes of this study were to analyze the post-exercise salivary nitrite (NO2-) and blood pressure (BP) responses to different exercise intensities in elderly women divided according to their ACE genotype. METHODS: Participants (n = 30; II/ID = 20 and DD = 10) underwent three experimental sessions: incremental test - IT (15 watts workload increase/3 min) until exhaustion; 20 min exercise 90% anaerobic threshold (90% AT); and 20 min control session without exercise. Volunteers had their BP and NO2- measured before and after experimental sessions. RESULTS: Despite both intensities showed protective effect on preventing the increase of BP during post-exercise recovery compared to control, post-exercise hypotension and increased NO2- release was observed only for carriers of the I allele (p < 0.05). CONCLUSION: Genotypes of the ACE gene may exert a role in post-exercise NO release and BP response.
Asunto(s)
Ejercicio Físico/fisiología , Genotipo , Hipertensión/genética , Óxido Nítrico/metabolismo , Peptidil-Dipeptidasa A/genética , Esfuerzo Físico/genética , Anciano , Alelos , Presión Sanguínea/genética , Prueba de Esfuerzo/métodos , Femenino , Humanos , Hipertensión/enzimología , Hipertensión/terapia , Persona de Mediana Edad , Nitritos/análisis , Saliva/química , Factores de TiempoRESUMEN
We report what is to our knowledge the first delivery of nanosecond laser pulses through flexible fibers to produce optical sparks in atmospheric-pressure gases. Our work employs a Nd:YAG laser beam (1.064 microm) delivered through a cyclic olefin polymer-coated silver hollow fiber. We studied the beam properties at the fiber exit as a function of the fiber launch geometry. We found that for a low-angle launch (approximately 0.01 rad half-angle), the exit beam has relatively high optical intensity (approximately 2 GW/cm2) and low light divergence (approximately 0.01 rad half-angle) and allows downstream spark formation. The effect of fiber bending on the exit beam and on the ability to make sparks is also investigated.
Asunto(s)
Trastornos de Deglución , Enfermeras Practicantes , Orofaringe/fisiopatología , Anciano , Anciano de 80 o más Años , Fenómenos Biomecánicos , Trastornos de Deglución/diagnóstico , Trastornos de Deglución/fisiopatología , Trastornos de Deglución/terapia , Femenino , Humanos , Factores de RiesgoRESUMEN
The Christmas holiday season is supposed to be a time of togetherness--a time with friends and family. But in most hospitals this is a time of disruption, loneliness and distress for both staff and patients. There are ways, however, to make the holiday season a more positive experience.
