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1.
Biophys Rev (Melville) ; 4(3): 031302, 2023 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-38510705

RESUMEN

The COVID-19 pandemic has changed the lives of many people around the world. Based on the available data and published reports, most people diagnosed with COVID-19 exhibit no or mild symptoms and could be discharged home for self-isolation. Considering that a substantial portion of them will progress to a severe disease requiring hospitalization and medical management, including respiratory and circulatory support in the form of supplemental oxygen therapy, mechanical ventilation, vasopressors, etc. The continuous monitoring of patient conditions at home for patients with COVID-19 will allow early determination of disease severity and medical intervention to reduce morbidity and mortality. In addition, this will allow early and safe hospital discharge and free hospital beds for patients who are in need of admission. In this review, we focus on the recent developments in next-generation wearable sensors capable of continuous monitoring of disease symptoms, particularly those associated with COVID-19. These include wearable non/minimally invasive biophysical (temperature, respiratory rate, oxygen saturation, heart rate, and heart rate variability) and biochemical (cytokines, cortisol, and electrolytes) sensors, sensor data analytics, and machine learning-enabled early detection and medical intervention techniques. Together, we aim to inspire the future development of wearable sensors integrated with data analytics, which serve as a foundation for disease diagnostics, health monitoring and predictions, and medical interventions.

2.
ChemSusChem ; 15(5): e202102313, 2022 Mar 08.
Artículo en Inglés | MEDLINE | ID: mdl-34978391

RESUMEN

This study employed operando spectroelectrochemical l and photoelectrochemical methods to investigate the charge carrier dynamics of photogenerated holes in hematite for ethanol oxidation and its possible over-oxidation. Ethanol oxidation was found to form acetaldehyde with around 100 % initial selectivity and faradaic efficiency. The overoxidation of acetaldehyde was suppressed by being unable to kinetically compete with ethanol oxidation in terms of turnover frequency by a factor of ten. Temperature-dependent rate law analyses were applied to determine the activation energies of these two oxidations. For the ethanol oxidation, the activation energy was 195 meV, compared to 398 meV for acetaldehyde oxidation. These results were correlated with the valence band potential to elucidate the advantage of using hematite for safer and sustainable value-added aldehyde synthesis compared to the industrial method. The dynamics of ethanol oxidation also addressed the challenges in broad-spectrum deep oxidation of organic compounds in water purification using metal oxides.

3.
IEEE Trans Image Process ; 30: 6485-6497, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-34110994

RESUMEN

Deep neural networks are fragile under adversarial attacks. In this work, we propose to develop a new defense method based on image restoration to remove adversarial attack noise. Using the gradient information back-propagated over the network to the input image, we identify high-sensitivity keypoints which have significant contributions to the image classification performance. We then partition the image pixels into the two groups: high-sensitivity and low-sensitivity points. For low-sensitivity pixels, we use a total variation (TV) norm-based image smoothing method to remove adversarial attack noise. For those high-sensitivity keypoints, we develop a structure-preserving low-rank image completion method. Based on matrix analysis and optimization, we derive an iterative solution for this optimization problem. Our extensive experimental results on the CIFAR-10, SVHN, and Tiny-ImageNet datasets have demonstrated that our method significantly outperforms other defense methods which are based on image de-noising or restoration, especially under powerful adversarial attacks.

4.
Ecol Evol ; 9(4): 1578-1589, 2019 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-30847057

RESUMEN

Camera traps are a popular tool to sample animal populations because they are noninvasive, detect a variety of species, and can record many thousands of animal detections per deployment. Cameras are typically set to take bursts of multiple photographs for each detection and are deployed in arrays of dozens or hundreds of sites, often resulting in millions of photographs per study. The task of converting photographs to animal detection records from such large image collections is daunting, and made worse by situations that generate copious empty pictures from false triggers (e.g., camera malfunction or moving vegetation) or pictures of humans. We developed computer vision algorithms to detect and classify moving objects to aid the first step of camera trap image filtering-separating the animal detections from the empty frames and pictures of humans. Our new work couples foreground object segmentation through background subtraction with deep learning classification to provide a fast and accurate scheme for human-animal detection. We provide these programs as both Matlab GUI and command prompt developed with C++. The software reads folders of camera trap images and outputs images annotated with bounding boxes around moving objects and a text file summary of results. This software maintains high accuracy while reducing the execution time by 14 times. It takes about 6 seconds to process a sequence of ten frames (on a 2.6 GHZ CPU computer). For those cameras with excessive empty frames due to camera malfunction or blowing vegetation automatically removes 54% of the false-triggers sequences without influencing the human/animal sequences. We achieve 99.58% on image-level empty versus object classification of Serengeti dataset. We offer the first computer vision tool for processing camera trap images providing substantial time savings for processing large image datasets, thus improving our ability to monitor wildlife across large scales with camera traps.

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