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2.
Eur J Obstet Gynecol Reprod Biol ; 103(1): 18-21, 2002 Jun 10.
Artículo en Inglés | MEDLINE | ID: mdl-12039457

RESUMEN

INTRODUCTION: Lower plasma levels of vitamins may result in hyperhomocysteinemia, a known risk factor in pregnancy. As smoking may alter nutrition, we were interested in its effect on folate and Vitamin B(12) in pregnancy. MATERIALS AND METHODS: A cross-sectional study of 62 smoking and 76 non-smoking healthy pregnant women. Serum folic acid, Vitamin B(12) and homocysteine were measured at four points in pregnancy: 0-10, 11-20, 21-30 and 31-40 weeks. RESULTS: Folate concentrations of the smoking women decreased continuously during pregnancy, and were significantly lower than those of non-smoking women during the last 30 weeks. Vitamin B(12) levels decreased significantly in both groups. The homocysteine levels were higher in the smoking group during the second-half of pregnancy. DISCUSSION: Smoking women have lower and decreasing folate levels during pregnancy, possibly as a result of lower intake of these nutrients. Lower folate levels can lead to hyperhomocysteinemia, a known risk factor for several complications in pregnancy. This is an other important reason to convince pregnant women to refrain from smoking.


Asunto(s)
Ácido Fólico/sangre , Homocisteína/sangre , Fumar/sangre , Vitamina B 12/sangre , Estudios Transversales , Femenino , Edad Gestacional , Humanos , Hiperhomocisteinemia/complicaciones , Estado Nutricional , Embarazo , Complicaciones del Embarazo , Valores de Referencia
5.
Eur J Obstet Gynecol Reprod Biol ; 35(2-3): 283-9, 1990.
Artículo en Inglés | MEDLINE | ID: mdl-2185959

RESUMEN

In this report we present the prenatal ultrasonic and postmortem data of a male fetus of 25 weeks' gestational age with a lethal multiple pterygium syndrome. The importance of precise etiologic diagnosis in a midtrimester fetus with generalized edema and nuchal hygroma is emphasized.


Asunto(s)
Diagnóstico Prenatal , Pterigion/diagnóstico , Adulto , Autopsia , Diagnóstico Diferencial , Edema/diagnóstico , Femenino , Humanos , Linfangioma/diagnóstico , Embarazo , Pterigion/patología , Síndrome , Ultrasonografía
6.
Urol Int ; 44(2): 119-20, 1989.
Artículo en Inglés | MEDLINE | ID: mdl-2658240

RESUMEN

We report an unusual case of unilateral ureteral obstruction with secondary urinary extravasation by forniceal rupture as a complication of the Burch colposuspension procedure. Surprisingly, this complication has never been described before.


Asunto(s)
Complicaciones Posoperatorias/etiología , Obstrucción Ureteral/etiología , Incontinencia Urinaria de Esfuerzo/cirugía , Vagina/cirugía , Extravasación de Materiales Terapéuticos y Diagnósticos/etiología , Femenino , Humanos , Persona de Mediana Edad , Técnicas de Sutura
7.
Haemostasis ; 13(5): 335-40, 1983.
Artículo en Inglés | MEDLINE | ID: mdl-6654191

RESUMEN

13 patients suspected of intra-uterine growth retardation (IUGR) were treated with a combination of heparin and dipyridamole. The effect of this anticoagulant therapy on platelet count, clot retraction, fibrinogen degradation products, antithrombin III (AT-III), plasminogen, fibrinogen and platelet aggregation induced by epinephrine, ADP, collagen and ristocetin has been examined. All parameters were measured both before and after treatment with heparin-dipyridamole. The results were compared with the results from a control group consisting of pregnant women of the same gestational age using no medication and not suspected of IUGR (n = 17). A significant decrease in the clot retraction was observed in patients with IUGR as compared to pregnant controls (p less than 0.05). A significant decrease in the AT-III level (p less than 0.01) and a significant increase (p less than 0.01) in the fibrinogen level were observed after heparin-dipyridamole treatment of patients suspected of IUGR. We conclude that the combination of a high fibrinogen and a low AT-III level will cause an increased risk for the development of thrombosis upon termination of treatment. We also observed that heparin clearance is increased during pregnancy.


Asunto(s)
Dipiridamol/uso terapéutico , Retardo del Crecimiento Fetal/tratamiento farmacológico , Heparina/uso terapéutico , Adolescente , Adulto , Retracción del Coagulo , Femenino , Productos de Degradación de Fibrina-Fibrinógeno/análisis , Humanos , Agregación Plaquetaria , Recuento de Plaquetas , Embarazo
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