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Scand J Gastroenterol ; 50(12): 1500-7, 2015.
Artículo en Inglés | MEDLINE | ID: mdl-26083798

RESUMEN

OBJECTIVE: Continuous infusion of levodopa carbidopa intestinal gel (LCIG) is associated with a significant improvement in the symptoms and quality of life of selected patients with advanced Parkinson's disease. Percutaneous endoscopic gastrostomy with jejunal extension (PEG/J) was first described in 1998 and has become the most common and standard technique for fixing the tubing in place for LCIG infusion. MATERIAL AND METHODS: A workshop was held in Stockholm, Sweden, to discuss the PEG/J placement for the delivery of LCIG in Parkinson's disease patients with the primary goal of providing guidance on best practice for the Nordic countries. RESULTS: Suggested procedures for preparation of patients for PEG/J placement, aftercare, troubleshooting and redo-procedures for use in the Nordic region are described and discussed. CONCLUSIONS: LCIG treatment administered through PEG/J-tubes gives a significant increase in quality of life for selected patients with advanced Parkinson's disease. Although minor complications are common, serious complications are infrequent, and the tube insertion procedures have a good safety record. Further development of delivery systems and evaluation of approaches designed to reduce the demand for redo endoscopy are required.


Asunto(s)
Antiparkinsonianos/administración & dosificación , Carbidopa/administración & dosificación , Gastrostomía/métodos , Levodopa/administración & dosificación , Enfermedad de Parkinson/cirugía , Geles , Humanos , Enfermedad de Parkinson/terapia , Selección de Paciente , Complicaciones Posoperatorias , Calidad de Vida , Países Escandinavos y Nórdicos
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