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1.
J Phys Chem Lett ; 12(7): 1973-1978, 2021 Feb 25.
Artículo en Inglés | MEDLINE | ID: mdl-33594881

RESUMEN

Herein, we employed lead-free Cs3Cu2I5 perovskite films as the functional layers to construct Al/Cs3Cu2I5/ITO memory devices and systematically investigated the impact on the corresponding resistive switching (RS) performance via adding different amounts of hydroiodic acid (HI) in Cs3Cu2I5 precursor solution. The results demonstrated that the crystallinity and morphology of the Cs3Cu2I5 films can be improved and the resistive switching performance can be modulated by adding an appropriate amount of HI. The obtained Cs3Cu2I5 films by adding 5 µL HI exhibit the fewest lattice defects and flattest surface (RMS = 13.3 nm). Besides, the memory device, utilizing the optimized films, has a low electroforming voltage (1.44 V), a large on/off ratio (∼65), and a long retention time (104 s). The RS performance impacted by adding HI, providing a scientific strategy for improving the RS performance of iodine halide perovskite-based memories.

2.
ACS Appl Mater Interfaces ; 12(20): 23094-23101, 2020 May 20.
Artículo en Inglés | MEDLINE | ID: mdl-32336082

RESUMEN

Recently, several types of lead halide perovskites have been demonstrated as active layers in resistive switching memory or artificial synaptic devices for neuromorphic computing applications. However, the thermal instability and toxicity of lead halide perovskites severely restricted their further practical applications. Herein, the environmentally friendly and uniform Cs3Cu2I5 perovskite films are introduced to act as the active layer in the Ag/Cs3Cu2I5/ITO memristor. Generally, the Ag ions could react with iodide ions and form AgIx compounds easily, so the Ag/PMMA/Cs3Cu2I5/ITO memristor was designed by employing the ultrathin polymethylmethacrylate (PMMA) layer to avoid the direct contact between the top Ag electrode and Cs3Cu2I5 perovskite films. After optimization, the obtained memristor demonstrated bipolar resistive switching with low operating voltage (< ±1 V), large on/off ratio (102), stable endurance (100 cycles), and long retention (>104 s). Additionally, biological synaptic behaviors including long-term potentiation and long-term depression have been investigated. By using the MNIST handwritten recognition data set, the handwritten recognition rate based on experimental data could reach 94%. In conclusion, our work provides the opportunity of exploring the novel application for the development of next-generation neuromorphic computing based on lead-free halide perovskites.

3.
Heart Surg Forum ; 21(6): E513-E521, 2018 12 19.
Artículo en Inglés | MEDLINE | ID: mdl-30604677

RESUMEN

OBJECTIVE: The aim of this study was to determine whether N-acetylcysteine (NAC) has an effect on acute kidney injury (AKI) in chronic kidney disease patients undergoing cardiac surgery. METHODS: We reviewed literature through PubMed, Medline through PubMed and OVID, The Cochrane Library, Wan Fang Database, China Biology Medicine Database, Chinese Periodical Database, China Knowledge Resource Integrated Database, and Chinese Clinical Trial Registry (1980 to July 10, 2018). Two investigators independently collected the data and assessed the quality of each study. RevMan 5.3 was used for the present metaanalysis. RESULTS: A total of 5 RCTs (N = 678 participants) were included in the primary analysis. Pooled analysis showed that intravenous infusion of NAC significantly reduced the incidence of AKI (RR = 0.77, 95% = 0.63 to 0.94, P < .01) and that NAC could decrease the adverse cardiac events (RR = 0.83, 95% = 0.70 to 0.97, P < .05), but that it may increase the length of stay in the ICU (mean difference [MD] = 2.1, 95% CI = 1.61 to 2.60, P < .01). There were no statistically significant differences between the 2 groups in the requirement for renal replacement therapy(RRT) (RR = 1.33, 95% = 0.63 to 2.81, P = .45) and all-cause mortality (RR = 0.51, 95% = 0.25 to 1.06, P = .07). CONCLUSION: Our study shows that intravenous infusion of NAC could prevent postoperative AKI in preexisting-renal-failure patients undergoing cardiac surgery.


Asunto(s)
Acetilcisteína/uso terapéutico , Lesión Renal Aguda/prevención & control , Antiinflamatorios/uso terapéutico , Antioxidantes/uso terapéutico , Procedimientos Quirúrgicos Cardíacos/efectos adversos , Insuficiencia Renal Crónica/complicaciones , Acetilcisteína/administración & dosificación , Administración Oral , Antiinflamatorios/administración & dosificación , Antioxidantes/administración & dosificación , Humanos , Infusiones Intravenosas , Unidades de Cuidados Intensivos , Tiempo de Internación , Complicaciones Posoperatorias/prevención & control , Insuficiencia Renal Crónica/terapia , Terapia de Reemplazo Renal
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