[Study on preparation of phenols gastric floating tablet].

OBJECTIVE: To study the preparation of phenols gastric floating tablet. METHOD: The tablets which were prepared using Eudragit IV, HPMC(K4M), MCC101 and Octadecanol as excipients were evaluated by vitro floatation and releasing performance. The pressure of preparationg was also study to select the optimal preparation. RESULT: The tablets were successfully prepared in which the drug, Eudragit IV, Octadecanol were 31% respectively,and MCC101 was 7%. And 3-4 kg was found to be the eligible pressure. CONCLUSION: The study was found to be effective in the process of phenols gastric floating tablet.