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1.
Front Public Health ; 12: 1390511, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-39114526

RESUMEN

Objective: To determine the relationship between domain-specific physical activity (PA) (e.g., occupational PA [OPA], transport-related PA [TPA], and recreational PA [RPA]) and cognitive function in older adults. Methods: The data was obtained from the 2011-2014 cycle of the NHANES. We utilized weighted multivariate linear regression models among the included 2,924 people aged 60 years or older for our purposes. Results: RPA and total PA according to WHO guidelines were associated with verbal fluency (RPA ß: 1.400, 95% CI: 0.776, 2.024, p = 0.002; total PA ß: 1.115, 95% CI: 0.571, 1.659, p = 0.001), processing speed and executive function (RPA ß: 2.912, 95% CI. 1.291, 4.534, p = 0.005; total PA ß: 2.974, 95% CI: 1.683, 4.265, p < 0.001) were positively correlated, and total PA was correlated with delayed memory performance (ß: 0.254, 95% CI: 0.058, 0.449, p = 0.019). No significant association was observed between OPA, TPA, and various aspects of cognitive function among individuals over 60 years. Conclusion: There was no noteworthy correlation discovered between OPA and TPA in relation to cognitive function. However, RPA and total PA exhibited significant associations with verbal fluency, processing speed, and executive function. Additionally, maintaining PA levels ranging from 600 to 1,200 MET-min/week would yield the most favorable outcomes for cognitive function.


Asunto(s)
Cognición , Ejercicio Físico , Encuestas Nutricionales , Humanos , Femenino , Masculino , Anciano , Cognición/fisiología , Persona de Mediana Edad , Función Ejecutiva/fisiología , Anciano de 80 o más Años , Estados Unidos
2.
Complement Ther Clin Pract ; 57: 101898, 2024 Aug 26.
Artículo en Inglés | MEDLINE | ID: mdl-39190950

RESUMEN

OBJECTIVE: Stroke is a major public health threat, and both physical activity (PA) and diet are modifiable risk factors for stroke. This study assessed the interaction and joint effects of PA and the dietary inflammatory index (DII) on stroke. METHODS: We included 18,676 participants from the 2007-2020 National Health and Nutrition Examination Survey. The independent associations, interactions, and joint effects of PA and the DII on stroke were assessed by weighted multivariable logistic regression. RESULTS: The weighted mean age of the participants was 48.24 years, and comprised 703 individuals who had experienced a stroke. After adjusting for confounders, increased stroke risk was independently associated with a higher DII (Q4, odds ratio [OR]: 1.72, 95 % confidence interval [CI]: 1.27-2.34) and insufficient PA (inactive, OR: 1.37, 95 % CI: 1.05-1.78). No significant multiplicative (OR: 1.11, 95 % CI: 0.34-1.93) or additive (relative excess risk due to interaction: 0.45, 95 % CI: 0.35-1.25) interactions were found between DII and PA. The results of joint associations indicated that individuals who consumed the most pro-inflammatory diet (DII, Q4) and were physically inactive (OR: 2.39, 95 % CI: 1.61-3.56) had the highest stroke risk than those who consumed the most anti-inflammatory diet (DII, Q1) and were physically active. CONCLUSION: Active PA and low DII scores are independent protective factors against stroke. Although the multiplicative and additive effects of the DII and PA on stroke risk are not statistically significant, the analysis of their joint effects suggest that individuals who consume anti-inflammatory diets and exhibit active PA consistently have the lowest risk of stroke.

3.
ACS Sens ; 9(7): 3773-3782, 2024 Jul 26.
Artículo en Inglés | MEDLINE | ID: mdl-38918891

RESUMEN

Exposure to mustard gas can cause damage or death to human beings, depending on the concentration and duration. Thus, developing high-performance mustard-gas sensors is highly needed for early warning. Herein, ultrathin WO3 nanosheet-supported Pd nanoparticles hybrids (WO3 NSs/Pd) are prepared as chemiresistive sulfur mustard simulant (e.g., 2-chloroethyl ethyl sulfide, 2-CEES) gas sensors. As a result, the optimal WO3 NSs/Pd-2 (2 wt % of Pd)-based sensor exhibits a high response of 8.5 and a rapid response/recovery time of 9/92 s toward 700 ppb 2-CEES at 260 °C. The detection limit could be as low as 15 ppb with a response of 1.4. Moreover, WO3 NSs/Pd-2 shows good repeatability, 30-day operating stability, and good selectivity. In WO3 NSs/Pd-2, ultrathin WO3 NSs are rich in oxygen vacancies, offer more sites to adsorb oxygen species, and make their size close to or even within the thickness of the so-called electron depletion layer, thus inducing a large resistance change (response). Moreover, strong metal-support interactions (SMSIs) between WO3 NSs and Pd nanoparticles enhance the catalytic redox reaction performance, thereby achieving a superior sensing performance toward 2-CEES. These findings in this work provide a new approach to optimize the sensing performance of a chemiresistive sensor by constructing SMSIs in ultrathin metal oxides.


Asunto(s)
Gas Mostaza , Óxidos , Paladio , Tungsteno , Tungsteno/química , Paladio/química , Gas Mostaza/análisis , Gas Mostaza/química , Gas Mostaza/análogos & derivados , Óxidos/química , Límite de Detección , Nanopartículas del Metal/química , Nanoestructuras/química , Sustancias para la Guerra Química/análisis , Sustancias para la Guerra Química/química , Técnicas Electroquímicas/métodos
4.
ACS Omega ; 9(24): 26450-26457, 2024 Jun 18.
Artículo en Inglés | MEDLINE | ID: mdl-38911716

RESUMEN

The modeling of ceramics with complex geometric structures currently depends on the handcrafted mode, with long cycles, high costs, and low efficiency; additive manufacturing (AM) technology can solve this problem well. Herein, the porcelain clay paste was successfully prepared for the direct ink writing (DIW) 3D printing process of ceramics with complex geometric structures, and the effects of sodium citrate (SC) content on the rheological properties and DIW 3D printability of the porcelain clay paste were investigated in detail. The SC has a vital role in the rheological behavior of porcelain clay paste. Adding SC increases the absolute zeta potential and decreases the viscosity of the paste, while a high SC content will lead to a low storage modulus of the paste. The porcelain clay paste with an SC content of 0.05% and a paste solid content of 75% possesses suitable rheological properties and a storage modulus for DIW 3D printing. The as-prepared porcelain clay paste has high DIW 3D printability at a pressure of 0.5 MPa, and a 3D-printed green body with a well-densified structure can be achieved. After being sintered, the 3D-printed ceramic exhibits high densification and mechanical properties. A green body with complex geometric structures is quickly and precisely modeled by the DIW 3D printing process with the resultant porcelain clay paste as the raw material. This work provides a practical approach to rapidly fabricating ceramics with complex geometrical structures.

5.
Materials (Basel) ; 17(12)2024 Jun 07.
Artículo en Inglés | MEDLINE | ID: mdl-38930171

RESUMEN

Iron red, a traditional Jingdezhen overglaze color, is primarily colored with iron oxide (Fe2O3). In traditional processes, the main ingredient for the iron red overglaze color, raw iron red, is produced by calcining iron vitriol (FeSO4·7H2O). Analysis of ancient iron red porcelain samples indicates that the coloration is unstable, ranging from bright red to dark red and occasionally to black. Addressing this, the present study, from a ceramic technology standpoint, conducts a series of calcination experiments on industrial iron vitriol at varying temperatures. Utilizing methodologies such as differential scanning calorimetry-thermogravimetry (DSC-TG), Raman spectroscopy, X-ray diffraction (XRD), scanning electron microscopy with X-ray energy dispersive spectrometry (SEM-EDS), and optical microscopy (OM), this research scientifically explores the impact of iron vitriol's calcination temperature on the coloration of traditional Jingdezhen iron red overglaze color. The findings indicate that from room temperature to 550 °C, the dehydration of iron vitriol resulted in the formation of Fe2(SO4)3 and a minimal amount of α-Fe2O3, rendering the iron red overglaze color a yellowish-red shade. At 650 °C, the coexistence of Fe2(SO4)3 and α-Fe2O3 imparted a brick-red color to the iron red. As the temperature was elevated to 700 °C, the desulfurization of Fe2(SO4)3 produced α-Fe2O3, transitioning the iron red to an orange red. With further temperature increase to 750 °C, the particle size of α-Fe2O3 grew and the crystal reflectivity decreased, resulting in a purplish-red hue. Throughout this stage, the powder remained in a single α-Fe2O3 phase. Upon further heating to 800 °C, the crystallinity of α-Fe2O3 enhanced, giving the iron red overglaze color a dark red or even black appearance.

6.
J Virol ; 98(7): e0060624, 2024 Jul 23.
Artículo en Inglés | MEDLINE | ID: mdl-38809020

RESUMEN

Rabies virus (RABV) is highly lethal and triggers severe neurological symptoms. The neuropathogenic mechanism remains poorly understood. Ras-related C3 botulinum toxin substrate 1 (Rac1) is a Rho-GTPase that is involved in actin remodeling and has been reported to be closely associated with neuronal dysfunction. In this study, by means of a combination of pharmacological inhibitors, small interfering RNA, and specific dominant-negatives, we characterize the crucial roles of dynamic actin and the regulatory function of Rac1 in RABV infection, dominantly in the viral entry phase. The data show that the RABV phosphoprotein interacts with Rac1. RABV phosphoprotein suppress Rac1 activity and impedes downstream Pak1-Limk1-Cofilin1 signaling, leading to the disruption of F-actin-based structure formation. In early viral infection, the EGFR-Rac1-signaling pathway undergoes a biphasic change, which is first upregulated and subsequently downregulated, corresponding to the RABV entry-induced remodeling pattern of F-actin. Taken together, our findings demonstrate for the first time the role played by the Rac1 signaling pathway in RABV infection and may provide a clue for an explanation for the etiology of rabies neurological pathogenesis.IMPORTANCEThough neuronal dysfunction is predominant in fatal rabies, the detailed mechanism by which rabies virus (RABV) infection causes neurological symptoms remains in question. The actin cytoskeleton is involved in numerous viruses infection and plays a crucial role in maintaining neurological function. The cytoskeletal disruption is closely associated with abnormal nervous symptoms and induces neurogenic diseases. In this study, we show that RABV infection led to the rearrangement of the cytoskeleton as well as the biphasic kinetics of the Rac1 signal transduction. These results help elucidate the mechanism that causes the aberrant neuronal processes by RABV infection and may shed light on therapeutic development aimed at ameliorating neurological disorders.


Asunto(s)
Citoesqueleto de Actina , Actinas , Virus de la Rabia , Transducción de Señal , Proteína de Unión al GTP rac1 , Proteína de Unión al GTP rac1/metabolismo , Proteína de Unión al GTP rac1/genética , Humanos , Citoesqueleto de Actina/metabolismo , Animales , Virus de la Rabia/fisiología , Actinas/metabolismo , Receptores ErbB/metabolismo , Receptores ErbB/genética , Quinasas p21 Activadas/metabolismo , Quinasas p21 Activadas/genética , Quinasas Lim/metabolismo , Quinasas Lim/genética , Internalización del Virus , Rabia/metabolismo , Rabia/virología , Línea Celular , Fosfoproteínas/metabolismo , Fosfoproteínas/genética , Factores Despolimerizantes de la Actina/metabolismo
7.
Brain Commun ; 6(2): fcae058, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38444912

RESUMEN

The hub-and-spoke theory of semantic representation fractionates the neural underpinning of semantic knowledge into two essential components: the sensorimotor modality-specific regions and a crucially important semantic hub region. Our previous study in patients with semantic dementia has found that the hub region is located in the left fusiform gyrus. However, because this region is located within the brain damage in patients with semantic dementia, it is not clear whether the semantic deficit is caused by structural damage to the hub region itself or by its disconnection from other brain regions. Stroke patients do not have any damage to the left fusiform gyrus, but exhibit amodal and modality-specific deficits in semantic processing. Therefore, in this study, we validated the semantic hub region from a brain network perspective in 79 stroke patients and explored the white matter connections associated with it. First, we collected data of diffusion-weighted imaging and behavioural performance on general semantic tasks and modality-specific semantic tasks (assessing object knowledge on form, colour, motion, sound, manipulation and function). We then used correlation and regression analyses to examine the association between the nodal degree values of brain regions in the whole-brain structural network and general semantic performance in the stroke patients. The results revealed that the connectivity of the left fusiform gyrus significantly predicted general semantic performance, indicating that this region is the semantic hub. To identify the semantic-relevant connections of the semantic hub, we then correlated the white matter integrity values of each tract connected to the left fusiform gyrus separately with performance on general and modality-specific semantic processing. We found that the hub region accomplished general semantic processing through white matter connections with the left superior temporal pole, middle temporal gyrus, inferior temporal gyrus and hippocampus. The connectivity between the hub region and the left hippocampus, superior temporal pole, middle temporal gyrus, inferior temporal gyrus and parahippocampal gyrus was differentially involved in object form, colour, motion, sound, manipulation and function processing. After statistically removing the effects of potential confounding variables (i.e. whole-brain lesion volume, lesion volume of regions of interest and performance on non-semantic control tasks), the observed effects remained significant. Together, our findings support the role of the left fusiform gyrus as a semantic hub region in stroke patients and reveal its crucial connectivity in the network. This study provides new insights and evidence for the neuroanatomical organization of semantic memory in the human brain.

8.
Front Microbiol ; 15: 1354936, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38380102

RESUMEN

Rabies is a fatal zoonotic disease that poses a threat to public health. Rabies virus (RABV) is excreted in the saliva of infected animals, and is primarily transmitted by bite. The role of the salivary glands in virus propagation is significant, but has been less studied in the pathogenic mechanisms of RABV. To identify functionally important genes in the salivary glands, we used RNA sequencing (RNA-seq) to establish and analyze mRNA expression profiles in parotid tissue infected with two RABV strains, CVS-11 and PB4. The biological functions of differentially expressed genes (DEGs) were determined by Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis, which revealed 3,764 DEGs (678 up-regulated and 3,086 down-regulated) in the CVS-11 infected group and 4,557 DEGs (874 up-regulated and 3,683 down-regulated) in the PB4 infected group. Various biological processes are involved, including the salivary secretion pathway and the phosphatidylinositol 3-kinase-Akt (PI3K-Akt) signaling pathway. This study provides the first mapping of the transcriptome changes in response to RABV infection in parotid tissue, offering new insights into the study of RABV-affected salivary gland function and RABV pathogenic mechanisms in parotid tissue. The salivary gland-enriched transcripts may be potential targets of interest for rabies disease control.

9.
RSC Adv ; 14(5): 3611-3616, 2024 Jan 17.
Artículo en Inglés | MEDLINE | ID: mdl-38264269

RESUMEN

Typical small organic dyes exhibit excellent UV absorption capabilities and are commonly used as additives to shield plastic films from photoaging. However, their tendency to decompose easily and migrate rapidly within a polymer matrix limits their service life. Herein we prepared g-C3N4 nanosheets and fabricated g-C3N4/PBAT films to investigate the effects of g-C3N4 on UV shielding and plasticizing of a biodegradable PBAT film. Photophysical characterizations revealed that an improved UV light barrier performance was achieved on g-C3N4/PBAT films compared to pure PBAT. Furthermore, the photoaging results show that g-C3N4 can stably exist in the PBAT matrix, enabling the aged g-C3N4/PBAT films to maintain their effective UV shielding ability, whereas the aged benzophenone (UV-0)/PBAT film shows a substantial decrease in UV light absorption due to the photodecomposition of UV-0. Additionally, g-C3N4 acted as a reinforcing material for PBAT, as evidenced by the approximately 1.5-fold increase in longitudinal tear strength and 1.6-fold increase in tensile strength of g-C3N4/PBAT films compared to pure PBAT. Remarkably, even after 100 hours of photoaging, the aged g-C3N4/PBAT films retained their favorable mechanical properties. This study highlights the potential of g-C3N4 as a new type of UV shield additive for future practical applications in protecting biodegradable plastic from photoaging.

10.
Nanotechnology ; 35(9)2023 Dec 15.
Artículo en Inglés | MEDLINE | ID: mdl-38029450

RESUMEN

As an ultra-wide bandgap semiconductor, gallium oxide (Ga2O3) has been extensively applied in solar-blind photodetectors (PDs) owing to the absorbance cut-off wavelength of shorter than 280 nm, and the optimized technologies of detection performance is seriously essential for its further usages. Herein, a feasible thermal reorder engineering method was performed through annealing Ga2O3films in vacuum, O2and oxygen plasma atmospheres, realizing to tune solar-blind photosensing performance of Ga2O3PDs. Thermal treatment, in fact a crystal reorder process, significantly suppressed the noise in Ga2O3-based PDs and enhanced the photo-sensitivity, with the dark current decreasing from 154.63 pA to 269 fA and photo-to-dark current ratio magically raising from 288 to 2.85 × 104. This achievement is dependent of energy-band modulation in Ga2O3semiconductor, that is certified by first-principles calculation. Additionally, annealing in oxygen atmospheres notably reduces the concentration of oxygen vacancies in the surface of films, thereby improving the performance of the PDs; the oxygen vacancy is extremely concerned in oxide semiconductors in the view of physics of surface defects. In all, this work could display a promising guidance for modulating the performance of PDs based on wide bandgap oxide semiconductor, especially for hot Ga2O3issue.

11.
Medicine (Baltimore) ; 102(36): e35117, 2023 Sep 08.
Artículo en Inglés | MEDLINE | ID: mdl-37682133

RESUMEN

RATIONALE: Cases of respiratory dysfunction due to phrenic nerve sacrifice during resection of massive mediastinal tumor have rarely been studied in detail. Diaphragmatic dysfunction in such cases can lead to potentially fatal respiratory and circulatory disturbances. Therefore, timely diagnosis and intervention are important. Conservative rehabilitation therapy is the first choice for respiratory dysfunction due to diaphragmatic dysfunction. PATIENT CONCERNS, DIAGNOSES AND INTERVENTIONS: We present 3 patients with respiratory dysfunction due to phrenic nerve sacrifice during resection of massive mediastinal tumor. The diagnostic methods and therapeutic procedures for diaphragmatic dysfunction for each patient are described in detail. This study highlights the role of ventilator support combined with physical therapy in the treatment of respiratory dysfunction in such cases. The diagnosis of diaphragmatic dysfunction as well as the risk assessment of phrenic nerve involvement are also discussed. The modalities of ventilator support, including modes and parameters, are listed. OUTCOMES AND LESSONS: This study provides experiences of diagnosis and treatment of respiratory dysfunction due to phrenic nerve sacrifice during resection of massive mediastinal tumor. Timely diagnosis of diaphragmatic dysfunction primarily relies on clinical manifestations and radiography. Conservative rehabilitation therapy can improve or restore diaphragmatic function in majority of patients, and avert or delay the need for surgical intervention. Preoperative assessment of the risk of phrenic nerve involvement is important in such cases.


Asunto(s)
Neoplasias del Mediastino , Medicina , Humanos , Neoplasias del Mediastino/complicaciones , Neoplasias del Mediastino/cirugía , Nervio Frénico , Tratamiento Conservador , Diafragma/cirugía
12.
Viruses ; 15(9)2023 09 03.
Artículo en Inglés | MEDLINE | ID: mdl-37766277

RESUMEN

Classical swine fever virus (CSFV), which is a positive-sense, single-stranded RNA virus with an envelope, is a member of the Pestivirus genus in the Flaviviridae family. CSFV causes a severe and highly contagious disease in pigs and is prevalent worldwide, threatening the pig farming industry. The detailed mechanisms of the CSFV life cycle have been reported, but are still limited. Some receptors and attachment factors of CSFV, including heparan sulfate (HS), laminin receptor (LamR), complement regulatory protein (CD46), MER tyrosine kinase (MERTK), disintegrin, and metalloproteinase domain-containing protein 17 (ADAM17), were identified. After attachment, CSFV internalizes via clathrin-mediated endocytosis (CME) and/or caveolae/raft-dependent endocytosis (CavME). After internalization, CSFV moves to early and late endosomes before uncoating. During this period, intracellular trafficking of CSFV relies on components of the endosomal sorting complex required for transport (ESCRT) and Rab proteins in the endosome dynamics, with a dependence on the cytoskeleton network. This review summarizes the data on the mechanisms of CSFV attachment, internalization pathways, and intracellular trafficking, and provides a general view of the early events in the CSFV life cycle.


Asunto(s)
Virus de la Fiebre Porcina Clásica , Peste Porcina Clásica , Pestivirus , Animales , Porcinos , Virus de la Fiebre Porcina Clásica/metabolismo , Endocitosis
13.
ACS Appl Mater Interfaces ; 15(34): 40744-40752, 2023 Aug 30.
Artículo en Inglés | MEDLINE | ID: mdl-37592828

RESUMEN

Solar-blind UV photodetectors have outstanding reliability and sensitivity in flame detection without interference from other signals and response quickly. Herein, we fabricated a solar-blind UV photodetector based on a La2O3/ε-Ga2O3 p-n heterojunction with a typical type-II band alignment. Benefiting from the photovoltaic effect formed by the space charge region across the junction interface, the photodetector exhibited a self-powered photocurrent of 1.4 nA at zero bias. Besides, this photodetector demonstrated excellent photo-to-dark current ratio of 2.68 × 104 under 254 nm UV light illumination and at a bias of 5 V, and a high specific detectivity of 2.31 × 1011 Jones and large responsivity of 1.67 mA/W were achieved. Importantly, the La2O3/ε-Ga2O3 heterojunction photodetector can rapidly respond to flames in milliseconds without any applied biases. Based on the performances described above, this novel La2O3/ε-Ga2O3 heterojunction is expected to be a candidate for future energy-efficient fire detection.

14.
Analyst ; 148(19): 4659-4667, 2023 Sep 25.
Artículo en Inglés | MEDLINE | ID: mdl-37615041

RESUMEN

We report a fully integrated digital microfluidic absorbance detection system with an enhanced sensitivity for online bacterial monitoring. Through a 100 µm gap in the chip, our optical detection system has a detection sensitivity for a BCA protein concentration of 0.1 mg mL-1. The absorbance detection limit of our system is 1.4 × 10-3 OD units, which is one order of magnitude better than that of the existing studies. The system's linear region is 0.1-7 mg mL-1, and the dynamic range is 0-25 mg mL-1. We measured the growth curves of wild-type and E. coli transformed with resistance plasmids and mixed at different ratios on chip. We sorted out the bacterial species including highly viable single cells based on the difference in absorbance data of growth curves. We explored the changes in the growth curves of E. coli under different concentrations of resistant media. In addition, we successfully screened for the optimal growth environment of the bacteria, in which the growth rate of PET30a-DH5α (in a medium with 33 µg mL-1 kanamycin resistance) was significantly higher than that of a 1 mg mL-1 resistance medium. In conclusion, the enhanced digital microfluidic absorbance detection system exhibits exceptional sensitivity, enabling precise bacterial monitoring and growth curve analysis, while also laying the foundation for DMF-based automated bioresearch platforms, thus advancing research in the life sciences.


Asunto(s)
Microfluídica , Dispositivos Ópticos , Escherichia coli , Dispositivos Laboratorio en un Chip , Movimiento Celular
15.
J Colloid Interface Sci ; 650(Pt A): 193-202, 2023 Nov 15.
Artículo en Inglés | MEDLINE | ID: mdl-37402325

RESUMEN

Solar-driven electrochemical NO3- reduction reaction (NO3-RR) is a clean and sustainable strategy that can convert pollutant NO3- in wastewater to value-added NH3. In recent years, cobalt oxides-based catalysts have shown their intrinsic catalytic properties toward NO3-RR but still have room for improvement through catalyst design. Coupling metal oxides with noble metal has been demonstrated to improve electrochemical catalytic efficiency. Here, we use Au species to tune the surface structure of Co3O4 and improve the efficiency of NO3-RR to NH3. The obtained Au nanocrystals-Co3O4 catalyst exhibited an onset potential of 0.54 V vs RHE, NH3 yield rate of 27.86 µg/h·cm2, and Faradaic efficiency (FE) of 83.1% at 0.437 V vs RHE in an H-cell, which is much higher than Au small species (Au clusters or single atoms)-Co3O4 (15.12 µg/h·cm2) and pure Co3O4 (11.38 µg/h·cm2), respectively. Combined experiments with theory calculations, we attributed the enhanced performance of Au nanocrystals-Co3O4 to the reduced energy barrier of *NO hydrogenation to the *NHO and suppression of HER, which originated from the charge transfer from Au to Co3O4. Using an amorphous silicon triple-junction (a-Si TJ) as the solar cell and an anion exchange membrane electrolyzer (AME), an unassisted solar-driven NO3-RR to NH3 prototype was realized with a yield rate of 4.65 mg/h and FE of 92.1%.

16.
PhytoKeys ; 225: 199-209, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-37179575

RESUMEN

Argyreiasubrotunda, a new species from Yunnan Province, China, is described and illustrated. The new species resembles A.fulvocymosa and A.wallichii, but differs from these in the flowers with an entire or shallowly lobed corolla, as well as smaller elliptic bracts, lax flat-topped cymes and shorter corolla tubes. An updated key to the species of Argyreia from Yunnan province is also provided.

17.
Nanomaterials (Basel) ; 13(9)2023 Apr 24.
Artículo en Inglés | MEDLINE | ID: mdl-37176993

RESUMEN

Designing phosphors that are excited by blue light is extraordinarily important for white light-emitting diodes (w-LEDs). In the present study, a new Ruddlesden-Popper type of SZO:xEu3+ (x = 0.01~0.10) phosphors was developed using solid-state reactions. Interestingly, a Eu3+ doping-induced phase transformation from the Sr3Zr2O7 (cubic) to the SrZrO3 (orthorhombic) phase was observed, and the impact of the occupied sites of Eu3+ ions on the lifetime of Sr3Zr2O7:xEu3+ phosphors is discussed in detail. Diffuse reflectance spectroscopy results showed that the band gap of SZO:xEu3+ phosphors gradually increased from 3.48 eV for undoped Sr3Zr2O7 hosts to 3.67 eV for SZO:0.10Eu3+ samples. The fluorescence excitation spectrum showed that ultraviolet (300 nm), near-ultraviolet (396 nm) and blue light (464 nm) were all effective excitation pump sources of Sr3Zr2O7:xEu3+ phosphors, and the strongest emission at 615 nm originated from an electric dipole transition (5D0→7F2). CIE coordinates moved from orange (0.5969, 0.4267) to the reddish-orange region (0.6155, 0.3827), and the color purity also increased. The fabricated w-LED was placed on a 460 nm chip with a mixture of YAG:Ce3+ and SZO:0.1Eu3+ samples and showed "warm" white light with a color rendering index (CRI) of 81.8 and a correlation color temperature (CCT) of 5386 K, indicating great potential for application in blue chip white LEDs.

18.
Micromachines (Basel) ; 14(3)2023 Feb 23.
Artículo en Inglés | MEDLINE | ID: mdl-36984929

RESUMEN

Nowadays, the impact ionization coefficient in the avalanche breakdown theory is obtained using 1-D PN junctions or SBDs, and is considered to be a constant determined by the material itself only. In this paper, the impact ionization coefficient of silicon in a 2D lateral power device is found to be no longer a constant, but instead a function of the 2D coupling effects. The impact ionization coefficient of silicon that considers the 2D depletion effects in real-world devices is proposed and extracted in this paper. The extracted impact ionization coefficient indicates that the conventional empirical impact ionization in the Fulop equation is not suitable for the analysis of 2D lateral power devices. The veracity of the proposed impact ionization coefficient is validated by the simulations obtained from TCAD tools. Considering the complexity of direct modeling, a new prediction method using deep neural networks is proposed. The prediction method demonstrates 97.67% accuracy for breakdown location prediction and less than 6% average error for the impact ionization coefficient prediction compared with the TCAD simulation.

19.
Micromachines (Basel) ; 14(1)2023 Jan 07.
Artículo en Inglés | MEDLINE | ID: mdl-36677216

RESUMEN

Previous studies have shown that the pollutants in exhaust gas can cause performance deterioration in air-fuel oxygen sensors. Although the content of Pb in fuel oil is as low as 5 mg/L, the effect of long-term Pb accumulation on TiO2 oxygen sensors is still unclear. In this paper, the influence mechanism of Pb-containing additives in automobile exhaust gas on the response characteristics of TiO2 oxygen sensors was simulated and studied by depositing Pb-containing pollutants on the surface of a TiO2 sensitive film. It was found that the accumulation of Pb changed the surface gas adsorption state and reduced the activation energy of TiO2, thus affecting the steady-state response voltage and response speed of the TiO2-based oxygen sensor.

20.
Food Funct ; 14(2): 746-758, 2023 Jan 23.
Artículo en Inglés | MEDLINE | ID: mdl-36537006

RESUMEN

Live, inactivated Lactobacillus or their metabolites have various beneficial functions, which may alleviate food allergy. This study aimed to investigate the intervention effects of three forms of Lactobacillus delbrueckii subsp. bulgaricus (Ld) on cell degranulation, intestinal barrier function, and intestinal mucosal immunity against soybean allergy. First, the intervention effect of Ld on cell degranulation was investigated using the KU812 cell degranulation model. Then, the Caco-2 cell inflammation model was used to evaluate their anti-inflammatory capacity, and the cell monolayer model was constructed to test the protective effects of different forms of Ld on the intestinal barrier. Finally, mesenteric lymph node (MLN) cells from mice were used to assess the ability of different forms of Ld to regulate the balance of cytokines associated with food allergy in the immune tissue of the intestinal mucosa. Results showed that live bacteria and heat-inactivated bacteria could inhibit the degranulation of KU812 cells, mainly by significantly inhibiting the release of histamine, IL-6 and TNF-α. Both live bacteria and heat-inactivated bacteria could also suppress the increase of IL-6 and IL-8 in Caco-2 cells induced by lipopolysaccharide (LPS). The culture supernatant of bacteria and live bacteria showed better ability to maintain the integrity and permeability of the intestinal epithelial barrier. In addition, heat-inactivated bacteria could return the values of IFN-γ and IL-10 to normal levels and restore the balance of IFN-γ/IL-4, thereby reversing the immune deviation of MLN cells. Therefore, three forms of Ld have potential for the treatment of soybean allergy.


Asunto(s)
Antialérgicos , Hipersensibilidad , Lactobacillus delbrueckii , Humanos , Animales , Ratones , Lactobacillus delbrueckii/metabolismo , Antialérgicos/metabolismo , Células CACO-2 , Glycine max , Interleucina-6/metabolismo , Bacterias
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