1.
J Org Chem
; 87(21): 14342-14351, 2022 Nov 04.
Artículo
en Inglés
| MEDLINE
| ID: mdl-36200367
RESUMEN
An efficient copper-catalyzed synthesis of a variety of N,N-diphenyl-2-benzothiazolamines was developed. Starting from substituted 1-(2-iodophenyl)-3-phenylthioureas and substituted iodobenzenes, the reaction proceeded smoothly via a tandem manner in the presence of CuI to afford the corresponding N,N-diphenyl-2-benzothiazolamine derivatives with good functional group tolerance. The protocol features simple performance, easily available starting materials, a one-pot manner, and good functional group tolerance, providing a practical strategy for the preparation of poly-functionalized amines.