Removal of 48 per- and polyfluoroalkyl substances (PFAS) throughout processes in domestic and general industrial wastewater treatment plants: Implications for emerging alternatives risk control.

Wastewater acts as a significant sink and source of per- and polyfluoroalkyl substances (PFAS). This study investigated the occurrence, removal and mass flow of 48 emerging and legacy PFAS in 8 domestic and general industrial wastewater treatment plants (WWTPs) throughout entire treatment processes. In wastewater and sludge, 24 and 26 PFAS were detected, with concentrations of 246-27,100 ng/L and 91.6-214 ng/g, respectively. Predominant substances included 2H,2H-perfluorooctanoic acid (6:2 FTCA), 2H,2H-perfluorododecanoic acid (10:2 FTCA), and perfluorooctanoic acid (PFOA). Novel alternatives such as hexafluoropropylene oxide dimer acid (GenX) were not detected. Removal efficiency of total PFAS was 1-46 % in domestic WWTPs but negative in industrial WWTPs, with one industrial WWTP showing a 27-fold increase due to 6:2 FTCA generation. Median removal efficiency revealed that 9 out of 13 major PFAS decreased after treatment, while 4 increased. PFAS with -CH2- group showed weaker sludge sorption compared to those with perfluorinated carbon chains. Mass flow analysis revealed wastewater is the major fate rather than sludge for emerging PFAS. Increased mass flows of fluorotelomer carboxylic acids (FTCAs) and perfluorobutanesulfonic acid (PFBS) were observed at biochemical treatment and disinfection. The ecological risk assessment using a relative risk ranking model identified higher risks from PFBS, polyfluoroalkyl phosphate mono-esters, and FTCAs. Emerging PFAS pose challenges in removal and greater hazards to ecosystems, necessitating careful evaluation and restriction to address their risk.

Fire needle therapy for the treatment of cancer pain: a protocol for the systematic review and meta-analysis.

Background: Cancer patients frequently suffer pain as one of their symptoms. It includes acute and chronic pain and is one of the most feared symptoms for patients. About one-third of adults actively undergoing cancer treatment suffer from pain related to their condition. Cancer pain control remains suboptimal due to a lack of assessment, knowledge, and access. Fire needle therapy, a traditional Chinese medicine, offers a potentially beneficial addition to current pain management approaches. This protocol outlines a systematic review and meta-analysis to compile evidence and examine the pain-relieving effects and safety of fire needle therapy for cancer patients. Methods and analysis: We will systematically search China National Knowledge Infrastructure (CNKI), Wanfang Database, China Biology Medicine disc (CBM), China Science and Technology Journal Database (CSTJ or VIP), PubMed, Web of Science, Embase, Cochrane Central Registry of Controlled Trials (CENTRAL), Chinese Clinical Trial Registry (Chictr), Opengrey, Worldcat, and Scopus from inception through July 2023. Random control trials (RCTs) include all types of cancer patients (age ≥ 18 years) complaining of pain. The primary outcome will be changes in pain intensity measured by Visual Analogue Scale (VAS), Numerical Rating Scale (NRS), Neuropathic Pain Scale (NPS), or Brief Pain Inventory (BPI). Secondary outcomes include quality of life (EORTC QLQ-C30 and GCQ), performance status (KPS), times of burst pain, treatment response rate, the dose reduction of analgesic drugs, and side effects rates. Utilizing the Cochrane risk bias measurement tool: Risk of Bias 2 (RoB 2), the trials' quality will be evaluated, and meta-analysis will be performed using RevMan software (version 5.4). Discussion: This systematic review will be the first comprehensive review of the literature to provide a meta-analysis of fire needle therapy for cancer pain, including only Random control trials (RCTs). For the sake of transparency and to avoid future duplication, the publication of this protocol offers a clear illustration of the procedures utilized in this evaluation. The results of our future studies may provide a new approach and theoretical basis for the treatment of cancer pain by medical oncology professionals. Systematic review registration: https://www.crd.york.ac.uk/prospero/, identifier CRD42023418609.

[Characteristics of Water Environment and Its Influencing Factors in Zhari Namco Basin, Xizang].

Zhari Namco is situated in the alpine grassland belt of northwestern Xizang with a fragile ecological environment. As the third-largest lake in Xizang, there has been a long-term lack of research data concerning its basin water environment. In an effort to elucidate the surface water environment characteristics of the basin and the factors influencing them, an extensive investigation was conducted from August 2021 to June 2022, encompassing periods of high flow, low flow, and base flow. Further, the study also involved comprehensive assessments of the water chemistry characteristics and spatial-temporal variation in lake sampling sites of the basin that were not significant by using mathematical statistics, hydrochemical analysis, correlation analysis, and principal component analysis. The findings revealed the following： ① The water in the Zhari Namco Basin exhibited an alkaline nature, with dominant ionic compositions in the lake comprising Na+, SO42-, and Cl-, whereas the rivers were primarily characterized by Ca2+, HCO3-, and SO42-. ② The main pollutants exceeding established standards included sulfates, arsenic, chlorides, and total phosphorus. The study identified significant spatiotemporal variations in water quality. Temporally, the exceedance of sulfates, arsenic, and total phosphorus was most pronounced during high-flow periods, followed by that during low-flow and base flow periods, with chloride levels showing less temporal variation. Spatially, river water quality surpassed that of the lakes, with arsenic, total phosphorus, TDS, sulfate, chloride, K+, and Na+ concentrations in lakes 1 to 2 orders of magnitude higher than those in rivers. Water qualities exceeding the established standard were primarily found in the lake, with less spatial variations within the lake itself. ③ Hydrochemical processes within the basin were found to be primarily influenced by natural phenomena, including evaporation-concentration and rock weathering. Various elements entered the lakes via surface runoff, where they continuously accumulated under the influence of evaporation-concentration processes, ultimately leading to exceedances. ④ Temporal variations in water quality were primarily attributed to increased elemental loss and intensified evaporation during high-flow periods. The spatial discrepancies in water quality were predominantly a consequence of the differing hydrodynamic conditions between flowing water bodies and enclosed water bodies.

Population exposure to emerging perfluoroalkyl acids (PFAAs) via drinking water resources: Application of multivariate statistics and risk assessment models.

This study assessed the occurrence, origins, and potential risks of emerging perfluoroalkyl acids (PFAAs) for the first time in drinking water resources of Khyber Pakhtunkhwa, Pakistan. In total, 13 perfluoroalkyl carboxylic acids (PFCAs) with carbon (C) chains C4-C18 and 4 perfluoroalkyl sulfonates (PFSAs) with C chains C4-C10 were tested in both surface and ground drinking water samples using a high-performance liquid chromatography system (HPLC) equipped with an Agilent 6460 Triple Quadrupole liquid chromatography-mass spectrometry (LC-MS) system. The concentrations of ∑PFCAs, ∑PFSAs, and ∑PFAAs in drinking water ranged from 1.46 to 72.85, 0.30-8.03, and 1.76-80.88 ng/L, respectively. Perfluorobutanoic acid (PFBA), perfluorohexanoic acid (PFHxA), and perfluoropentanoic acid (PFPeA) were the dominant analytes in surface water followed by ground water, while the concentration of perfluorobutane sulfonate (PFBS), perfluorooctanoic acid (PFOA), perfluoroheptanoic acid (PFHpA), perfluorooctane sulfonate (PFOS), perfluorohexane sulfonate (PFHxS), perfluorononanoic acid (PFNA), perfluorodecanoic acid (PFDA), perfluoroundecanoic acid (PFUnDA), and perfluorododecanoic acid (PFDoDA) were greater than long-chain PFOA and PFOS. The correlation statistics, which showed a strong correlation (p < 0.05) between the PFAA analytes, potentially indicated the fate of PFAAs in the area's drinking water sources, whereas the hierarchical cluster analysis (HCA) and principal component analysis (PCA) statistics identified industrial, domestic, agricultural, and commercial applications as potential point and non-point sources of PFAA contamination in the area. From risk perspectives, the overall PFAA toxicity in water resources was within the ecological health risk thresholds, where for the human population the hazard quotient (HQ) values of individual PFAAs were < 1, indicating no risk from the drinking water sources; however, the hazard index (HI) from the ∑PFAAs should not be underestimated, as it may significantly result in potential chronic toxicity to exposed adults, followed by children.

Remarkable Contamination of Short- and Medium-Chain Chlorinated Paraffins in Free-Range Chicken Eggs from Rural Tibetan Plateau.

Rapid social-economic development introduces modern lifestyles into rural areas, not only bringing numerous modern products but also new pollutants, such as chlorinated paraffins (CPs). The rural Tibetan Plateau has limited industrial activities and is a unique place to investigate this issue. Herein we collected 90 free-range chicken egg pool samples across the rural Tibetan Plateau to evaluate the pollution status of CPs. Meanwhile, CPs in related soils, free-range chicken eggs from Jiangxi, and farmed eggs from markets were also analyzed. The median concentrations of SCCPs (159 ng g-1 wet weight (ww)) and MCCPs (1390 ng g-1 ww) in Tibetan free-range chicken eggs were comparable to those from Jiangxi (259 and 938 ng g-1 ww) and significantly higher than those in farmed eggs (22.0 and 81.7 ng g-1 ww). In the rural Tibetan Plateau, the median EDI of CPs via egg consumption by adults and children were estimated to be 81.6 and 220.2 ng kg-1 bw day-1 for SCCPs and 483.4 and 1291 ng kg-1 bw day-1 for MCCPs, respectively. MCCPs might pose potential health risks for both adults and children in the worst scenario. Our study demonstrates that new pollutants should not be ignored and need further attention in remote rural areas.

Transport and health risk of legacy and emerging per-and polyfluoroalkyl substances in the water cycle in an urban area, China: Polyfluoroalkyl phosphate esters are of concern.

Polyfluoroalkyl phosphate esters (PAPs) are a group of emerging alternatives to the legacy per- and polyfluoroalkyl substances (PFAS). To better understand the transport and risk of PAPs in the water cycle, 21 PFAS including 4 PAPs and 17 perfluoroalkyl acids were investigated in multiple waterbodies in an urban area, China. PFAS concentrations ranged from 85.8 to 206 ng/L, among which PAPs concentrations ranged from 35.0 to 71.8 ng/L, in river and lake water with major substances of perfluorooctanoic acid (PFOA), 6:2 fluorotelomer phosphate (6:2 monoPAP), and 8:2 fluorotelomer phosphate (8:2 monoPAP). As transport pathways, municipal wastewater and precipitation were investigated for PFAS mass loading estimation, and PAPs transported via precipitation more than municipal wastewater discharge. Concentrations of PFAS in tap water and raw source water were compared, and PAPs cannot be removed by drinking water treatment. In tap water, PFAS concentrations ranged from 132 to 271 ng/L and among them PAPs concentrations ranged from 41.6 to 61.9 ng/L. Human exposure and health risk to PFAS via drinking water were assessed, and relatively stronger health risks were induced from PFOS, PAPs, and PFOA. The environmental contamination and health risk of PAPs are of concern, and management implications regarding their sources, exposure, and hazards were raised.

Emerging and legacy per- and polyfluoroalkyl substances (PFAS) in fluorochemical wastewater along full-scale treatment processes: Source, fate, and ecological risk.

The increasing applications of emerging per- and polyfluoroalkyl substances (PFAS) have raised global concern. However, the release of emerging PFAS from the fluorochemical industry remains unclear. Herein, the occurrence of 48 emerging and legacy PFAS in wastewater from 10 fluorochemical manufacturers and mass flows of PFAS in a centralized wastewater treatment plant were investigated. Their distribution and ecological risk in neighboring riverine water were also evaluated. In wastewater from fluorochemical manufacturers, PFAS concentrations were in the range of 14,700-5200,000 ng/L and 2 H,2 H-perfluorooctanoic acid (6:2 FTCA), perfluorooctanoic acid (PFOA), N-ethyl perfluorooctane sulfonamide (N-EtFOSA), and 1 H,1 H,2 H,2 H-perfluorodecanesulfonate (8:2 FTS) were the major PFAS detected. Several PFAS displayed increased mass flows after wastewater treatment, especially PFOA and 6:2 FTCA. The mass flows of PFAS increased from - 20% to 233% after the activated sludge system but decreased by only 0-13% after the activated carbon filtration. In riverine water, PFAS concentrations were in the range of 5900-39,100 ng/L and 6:2 FTCA, 1 H,1 H,2 H,2 H-perfluorodecyl phosphate monoester (8:2 monoPAP), 1 H,1 H,2 H,2 H-perfluorooctyl phosphate monoester (6:2 monoPAP), PFOA, and perfluorohexanoic acid (PFHxA) were the major PFAS detected. PFOA and 6:2 FTCA exhibited comparable hazard quotients for ecological risk. Current wastewater treatment processes cannot fully remove various PFAS discharged by fluorochemical manufacturers, and further investigations on their risk are needed for better chemical management.

Isotopic Constraints on Sources and Transformations of Nitrate in the Mount Everest Proglacial Water.

Glacier melting exports a large amount of nitrate to downstream aquatic ecosystems. Glacial lakes and glacier-fed rivers in proglacial environments serve as primary recipients and distributors of glacier-derived nitrate (NO3-), yet little is known regarding the sources and cycling of nitrate in these water bodies. To address this knowledge gap, we conducted a comprehensive analysis of nitrate isotopes (δ15NNO3, δ18ONO3, and Δ17ONO3) in waters from the glacial lake and river of the Rongbuk Glacier-fed Basin (RGB) in the mountain Everest region. The concentrations of NO3- were low (0.43 ± 0.10 mg/L), similar to or even lower than those observed in glacial lakes and glacier-fed rivers in other high mountain regions, suggesting minimal anthropogenic influence. The NO3- concentration decreases upon entering the glacial lake due to sedimentation, and it increases gradually from upstream to downstream in the river as a soil source is introduced. The analysis of Δ17ONO3 revealed a substantial contribution of unprocessed atmospheric nitrate, ranging from 34.29 to 56.43%. Denitrification and nitrification processes were found to be insignificant in the proglacial water of RGB. Our study highlights the critical role of glacial lakes in capturing and redistributing glacier-derived NO3- and emphasizes the need for further investigations on NO3- transformation in the fast-changing proglacial environment over the Tibetan Plateau and other high mountain regions.

Soil contamination and carrying capacity across the Tibetan plateau using structural equation models.

Soil contamination is a major environmental issue worldwide. Compared with Arctic, European Alps and Rocky Mountains, the soil contamination and soil environment carrying capacity (SECC) of the Tibetan Plateau (TP) is not systematic and multidimensional. In this study, the levels, influencing factors including climate factors [(i.e., mean annual precipitation (MAP) and mean annual temperature (MAT)], socio-economic factors [(i.e., population, population density and gross domestic product (GDP)], vegetation coverage factor, soil factors [(i.e., pH, soil organic carbon (SOC), total phosphorus and total nitrogen] and topographic factors [(i.e., longitude, latitude and digital elevation model (DEM)] and carrying capacity of multiple soil contaminants [persistent organic pollutants (POPs), heavy metals (HMs) and microplastics (MPs)] was systematically studied. Results show that the spatial distribution of POPs in the eastern was higher than that in the western region, and the structural equation model (SEM) demonstrate that SOC and MAT were the key factors influencing distribution. Regarding HMs, except As, moderate and heavy pollution of the remaining elements were found in the northern and eastern TP regions, and pH and MAP were the main influencing factors. The MPs showed that the distribution of the patches was influenced by GDP and MAP. Furthermore, a higher SECC in the eastern region that gradually decreased from east to west. pH is the primary factors affecting SECC, followed by normalized difference vegetation index (NDVI). An increase of pH and NDVI by one unit is likely to make SECC scores decrease by 0.8 and increase by 0.32, respectively. Taken together, these studies provide a system, cost-effective, and quantitative framework for soil contamination and carrying capacity in the TP.

Bioaccumulation and risk mitigation of legacy and novel perfluoroalkyl substances in seafood: Insights from trophic transfer and cooking method.

Per- and polyfluoroalkyl substances (PFAS) have widespread application in industrial and civil areas due to their unique physical and chemical properties. With the increasingly stringent regulations of legacy PFAS, various novel alternatives have been developed and applied to meet the market demand. Legacy and novel PFAS pose potential threats to the ecological safety of coastal areas, however, little is known about their accumulation and transfer mechanism, especially after cooking treatment. This study investigated the biomagnification and trophic transfer characteristics of PFAS in seafood from the South China Sea, and assessed their health risks after cooking. Fifteen target PFAS were all detected in the samples, of which perfluorobutanoic acid (PFBA) was dominant with concentrations ranging from 0.76 to 4.12 ng/g ww. Trophic magnification factors (TMFs) > 1 were observed for perfluorooctane sulfonate (PFOS) and 6:2 chlorinated polyfluoroalkyl ether sulfonic acid (F-53B), indicating that these compounds experienced trophic magnification in the food web. The effects of different cooking styles on PFAS occurrence were further explored and the results suggested that ΣPFAS concentrations increased in most organisms after baking, while ΣPFAS amounts decreased basically after boiling and frying. Generally, there is a low health risk of exposure to PFAS when cooked seafood is consumed. This work provided quantitative evidence that cooking methods altered PFAS in seafood. Further, suggestions to mitigate the health risks of consuming PFAS-contaminated seafood were provided.

Optimizing the physiological pharmacokinetic model to rank the risks of persistent organic pollutants towards fish on the Tibetan Plateau.

Persistent organic pollutants (POPs) could pose adverse risks towards fish in aquatic environments. However, related risk assessments in remote regions are lacking. In this study we investigated three kinds of POPs in four common fish species (n = 62) from high-altitude rivers and lakes on the Tibetan Plateau. The results showed that the lipid weight concentrations of organochlorine pesticides (OCPs), polycyclic aromatic hydrocarbons (PAHs), and perfluoroalkyl substances (PFAS) in fish muscle followed the order Σ13PAHs (24.5-3354 ng/g) > Σ11PFAS (2.48-164 ng/g) > Σ7OCPs (1.61-82.2 ng/g), which is comparable to that found in other remote regions. The physiologically based pharmacokinetic (PBPK) model was optimized using physiological parameters specific to the sampled Tibetan fish to generate accurate effective concentration (EC) thresholds. Based on these measured concentrations and newly simulated EC thresholds, the ecological risk ratios for selected toxic POPs (dichlorodiphenyltrichloroethane (DDT), pyrene (Pyr), and perfluorooctane sulfonate (PFOS)) ranged from 8.53 × 10-8 to 2.03 × 10-5. Racoma tibetanus and Schizothorax macropogon were the most vulnerable Tibetan fish species. All the risk ratios were far below 1, indicating that there was no risk of POPs towards Tibetan fish. However, the risk ratios for emerging POPs (i.e., PFOS) were 2-3 orders of magnitude higher than for legacy POPs (i.e., DDT and Pyr), suggesting that monitoring of emerging POPs should be reinforced. Our study sheds light on the risk assessment of wildlife exposed to POPs in remote regions with limited toxicity data.

Estimating industrial process emission and assessing carbon dioxide equivalent of perfluorooctanoic acid (PFOA) and its salts in China.

Air pollution and climate change are closely linked because many greenhouse gases (GHGs) and air pollutants come from the same source. Perfluorinated compounds (PFCs) are new pollutants that have received high attention in recent years, as they are not only harmful to human health, but also important contributors to climate change. Therefore, PFCs are the key gases for the coordinated governance of air pollution and climate change. With the geographical shift of fluoropolymer production, the main emitters of perfluorooctanoic acid and its salts (PFOA/PFO) moved from North America, Europe and Japan to emerging Asian economies, especially China. In this study, industrial sources of PFOA/PFO in the Chinese atmosphere were identified, and its atmospheric emissions, carbon dioxide equivalent (CO2e) emissions and environmental risks were assessed. China released about 38.19 tons PFOA/PFO into the atmosphere through industrial activities in 2019, 97 % of which originated from the production of fluoropolymers. PFOA/PFO showed aggregative emission along the eastern coastal zone, especially in the Yangtze River Delta. Cumulative PFOA/PFO emission from all provinces equaled to 0.28-0.47 million tons CO2e, of which Jiangsu and Zhejiang took the lead, while Shanghai's CO2-equivalent emissions intensity of PFOA/PFO in terms of area, population, gross domestic product (GDP), and industrial added value took the first in China. The available monitoring data on atmospheric concentration of PFOA in urban and rural China implied that its distribution pattern was similar to PFOA/PFO emissions, that is, the concentrations in the eastern regions with the highest degree of industrialization were significantly higher than that in the central and western regions, and the PFOA concentrations in urban China were higher than that in the rural, which proved that industrial use was an important source of PFOA pollution and would cause significant risks to the environment.

Carbon flow through continental-scale ground logistics transportation.

The flourishing logistics in both developed and emerging economies leads to huge greenhouse gas (GHG) emissions; however, the emission fluxes are poorly constrained. Here, we constructed a spatial network of logistic GHG emissions based on multisource big data at continental scale. GHG emissions related to logistics transportation reached 112.14 Mt CO2-equivalents (CO2e), with seven major urban agglomerations contributing 63% of the total emissions. Regions with short transport distances and well-developed road infrastructure had relatively high emission efficiency. Underlying value flow of the commodities is accompanied by logistics carbon flow along the supply chain. The main driving factors affecting GHG emissions are driving speed and gross domestic product. It may mitigate GHG emissions by 27.50-1162.75 Mt CO2e in 15 years if a variety of energy combinations or the appropriate driving speed (65-70 km/h) is adopted. The estimations are of great significance to make integrated management policies for the global logistics sector.

Sources and health risks of heavy metals in soils and vegetables from intensive human intervention areas in South China.

Heavy metal pollution greatly harms the soil environment and poses threats to food safety and human health. This study aimed to quantify and analyze the sources of heavy metals and assess the health risks associated with the human intake of contaminated vegetables in South China. Heavy metals (Cd, As, Hg, Cu, Ni, Pb, Zn, and Cr) in soil and vegetables (leaf vegetables, legume vegetables, and cucurbits) were investigated and evaluated for contamination. By combining the correlation analysis (CA), positive matrix factorization (PMF), and GeoDetector model, source apportionments were comprehensively identified. Results showed that Cd was the predominant element in soils throughout the study area. Industrial (28.36 %, 20.24 %, 31.50 %), agricultural (27.19 %, 46.50 %, 27.30 %), besides traffic, atmospheric deposition and natural sources were identified as the dominant sources of heavy metals in GD01, GD02, and GD03, respectively. The human health risk assessment showed that the total non-cancer risk of heavy metals (i.e., Cr, Ni, As, Cd, and Pb) ingested through vegetables was 2.3E+00 for children and 9.67E-01 for adults, and the total cancer risk for children was 2.54E-02 and 1.07E-02 for adults, both of which exceeded acceptable levels. It is worth noting that children are more susceptible to health risks due to the consumption of contaminated vegetables than adults.

Perfluoroalkyl acids (PFAAs) in water along the entire coastal line of China: Spatial distribution, mass loadings, and worldwide comparisons.

Perfluoroalkyl acids (PFAAs) have been ubiquitously distributed in water environment worldwide for a long time, especially in the estuaries and coastal areas. In this study, the distribution characteristics of 12 PFAAs in 91 main river estuaries along the entire coast of China were analyzed for the first time, and the riverine PFAAs fluxes into the coastal marine environment were estimated. Based on a mini-review, the PFAAs pollution in the coast of China at a global scale was evaluated, which was intended to reveal the overall level of PFAAs and to provide a science basis for strengthening environmental management along the coast of China. The results showed that perfluorooctanoic acid (PFOA), perfluorobutanoic acid (PFBA), and perfluorobutane sulfonic acid (PFBS) were dominant in the whole coastal region, which indicated the usage of PFAAs was changing from long-chain PFAAs to short-chain substitutes in China. With regard to the spatial distribution, the high PFAAs concentrations were found in the coastal areas of south Bohai Sea, Shandong Province from the north while those in the south were generally lower when taking the Qinling Mountain and Huaihe River as a dividing line. The estimated PFAAs riverine mass loading in the whole coastal region was 131 tons per year, and the discharge flux of the Yangtze River accounted for more than half (73.5 tons). In comparison with global data, PFAAs concentrations in the coast of China was at a moderate level, and the detected hotspots of high levels were strongly influenced by fluorochemical industries. However, the mass loading of PFAAs was diversified due to geographical differences and abundant river discharges.

Optimizing the fugacity model to select appropriate remediation pathways for perfluoroalkyl substances (PFASs) in a lake.

Increased anthropogenic activities have caused contamination of perfluoroalkyl substances (PFASs) in lakes worldwide. However, how to remediate their contamination remains unclear. In this study, a heavily polluted lake, Baiyangdian Lake in China, was selected to investigate current PFASs levels in multimedia, stimulate their transport fate based upon an optimized fugacity model, and finally identify appropriate remediation pathways. From 2008-2019, the average concentrations of PFASs in the lake increased approximately 7-40 times in the environment and biota. Spatially, with continuous import of perfluorohexane sulfonate (PFHxS) and perfluorooctanoic acid (PFOA), barring fish, a noticeable north-south difference was distinguished in the PFASs composition in multimedia from the lake. Based on the optimized fugacity model simulation, the water phase was the primary transport path (~76.5%) for PFASs, with a total flux of 333 kg y-1. Compared with bioaccumulation fluxes in submerged plants (6.2 kg y-1), emerged plants (2.6 kg y-1), and fish (1.1 kg y-1), the exchange flux of PFASs between water and sediment remained high (~94 kg y-1). Considering remediation cost, sediment cleaning is currently the most cost-effective pathway, while harvesting submerged plant could be a promising pathway in the future. This study provides a basis for remediating PFASs-polluted lakes on a global scale.

Heavy metal pollution in the soil of a riverine basin: distribution, source, and potential hazards.

Soil pollution with heavy metals (HMs) has become a world environmental problem. This study focuses on surface soil contamination with Cr, Mn, Co, Ni, Cu, Zn, Cd, Hg, Pb, Fe, and Al, their sources, and potential hazards along the basin of River Swat, Pakistan. The average concentrations (mg/kg) of HMs were the most abundant for Al (24,730.19) followed by Fe (22,419.41) > Mn (386.78) > Zn (57.75) > Cr (38.07) > Ni (32.46) > Cu (23.43) > Pb (19.59) > Co (10.77) > Cd (3.18) > Hg (0.12). The concentrations of Cr and Mn in 5.45% each, Co in 10.90%, Zn in 27.27%, Cu in 36.36%, Ni in 41.81%, and Hg in 92.72% of the total soil samples exceeded their respective background values. The geostatistical approaches determined the distribution patterns of HM pollution along the basin, whereas the statistics of principal component analysis exposed the likely sources of HM contamination in the area. Pollution indices evaluated the overall HM distribution and pollution status in the area. Contamination factor showed a high degree of HM contamination in 82% of the total sampling sites, while the geo-accumulation index designated low to moderate contamination with Cr, Mn, Co, Ni, Cu, Zn, Hg, and Pb, and moderate to extreme contamination with Cd, Fe, and Al. The trend of ecological toxicity showed potential ups and downs along with the sites from low to considerable hazard (< 95 < PEHI < 190), whereas the human carcinogenic hazard was within the USEPA acceptable limits (1 × 10-7-1 × 10-4), but the non-carcinogenic hazard was higher than the threshold (HI > 1) for children because they are more exposed than adults.

Perfluoroalkyl substances in the surface water and fishes in Chaohu Lake, China.

The concentration and composition of 13 perfluoroalkyl substances (PFASs) in surface water and fishes in Chaohu Lake, China, were systematically studied in October 2019. Results showed that the PFASs composition has changed greatly. The concentration levels of perfluorooctane sulfonate (PFOS) in the surface water of Chaohu Lake have decreased significantly compared with past years. Perfluorobutanoic acid (PFBA) has become the dominant component, and it was mainly come from industrial wastewater. The highest concentration of perfluorooctanoic acid (PFOA) was measured in the lake inlet of the Baishitian River (southwest part), which mainly received domestic sewage. Different types of wastewater lead to varying compositions of PFASs in the lake water. PFOA and PFBS were homologous in some areas of Chaohu Lake, which reflected the unbalanced promotion of prohibition and substitution of long-chain PFASs around Chaohu Lake. On the basis of the risk quotient and tolerable daily intake assessment, drinking water and eating fish from Chaohu Lake do not lead to apparent PFAS risk, but PFOS in fish has evident bioaccumulation and biomagnification effects. PFOS-based human daily intake of Channa argus accounts for 22.4% of the tolerable daily intake. Thus, the risk caused by PFOS needs close attention. This study is useful for enhancing people's understanding of the environmental behavior and the risk of PFASs in Chaohu Lake.