Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 1 de 1
Filtrar
Más filtros












Base de datos
Intervalo de año de publicación
1.
Future Microbiol ; 18: 357-371, 2023 04.
Artículo en Inglés | MEDLINE | ID: mdl-37166186

RESUMEN

Aim: To investigate the antifungal potential of Macrocybe titans extracts against Candida albicans. Material & methods: Extracts were obtained as aqueous (EfraMat-22 and EfraMat-45) and methanolic/ethyl acetate fractions. Results: Broth microdilution and disk diffusion assays showed that EfraMat-45 provided the best results in terms of minimum inhibitory concentration. Scanning electron microscopy analysis revealed morphological changes and slight damage on the surfaces of cells exposed to EfraMat-45 at the MIC. Fluorescence microscopy analysis of the yeasts showed cell elongation. EfraMat-45 presented high levels of phenolic compounds and flavonoids, high antioxidant activity and absence of in vitro cytotoxicity. Conclusion: The results indicated that the aqueous extract of M. titans is highly promising as an antifungal agent.


Asunto(s)
Agaricales , Antifúngicos , Antifúngicos/farmacología , Candida albicans , Extractos Vegetales/farmacología , Pruebas de Sensibilidad Microbiana , Agua
SELECCIÓN DE REFERENCIAS
DETALLE DE LA BÚSQUEDA
...