Are We Exploring the Potential Role of Specialized Techniques in Muscle Hypertrophy?

Specialized resistance training techniques (e.g., drop-set, rest-pause) are commonly used by well-trained subjects for maximizing muscle hypertrophy. Most of these techniques were designed to allow a greater training volume (i.e., total repetitions×load), due to the supposition that it elicits greater muscle mass gains. However, many studies that compared the traditional resistance training configuration with specialized techniques seek to equalize the volume between groups, making it difficult to determine the inherent hypertrophic potential of these advanced strategies, as well as, this equalization restricts part of the practical extrapolation on these findings. In this scenario, the objectives of this manuscript were 1) to present the nuance of the evidence that deals with the effectiveness of these specialized resistance training techniques and - primarily - to 2) propose possible ways to explore the hypertrophic potential of such strategies with greater ecological validity without losing the methodological rigor of controlling possible intervening variables; and thus, contributing to increasing the applicability of the findings and improving the effectiveness of hypertrophy-oriented resistance training programs.

What influence does resistance exercise order have on muscular strength gains and muscle hypertrophy? A systematic review and meta-analysis.

The objectives of this paper were to: (a) systematically review studies that explored the effects of exercise order (EO) on muscular strength and/or hypertrophy; (b) pool their results using a meta-analysis; and (c) provide recommendations for the prescription of EO in resistance training (RT) programmes. A literature search was performed in four databases. Studies were included if they explored the effects of EO on dynamic muscular strength and/or muscle hypertrophy. The meta-analysis was performed using a random-effects model with Hedges' g effect size (ES). The methodological quality of studies was appraised using the TESTEX checklist. Eleven good-to-excellent methodological quality studies were included in the review. When all strength tests, that is, both in multi-joint (MJ) and single-joint (SJ) exercises were considered, there was no difference between the EOs (ES = -0.11; p = 0.306). However, there was a difference between the MJ-to-SJ and SJ-to-MJ orders for strength gains in the MJ exercises, favouring starting the exercise session with MJ exercises (ES = 0.32; p = 0.034), and the strength gains in the SJ exercises, favouring starting the exercise session with SJ exercises (ES = -0.58; p = 0.032). No significant effect of EO was observed for hypertrophy combining site-specific and indirect measures (ES = 0.03; p = 0.862). In conclusion, increases in muscular strength are the largest in the exercises performed at the beginning of an exercise session. For muscle hypertrophy, our meta-analysis indicated that both MJ-to-SJ and SJ-to-MJ EOs may produce similar results.

Training Programs Designed for Muscle Hypertrophy in Bodybuilders: A Narrative Review.

Bodybuilding is a sport that requires adequate training strategies in order to maximize skeletal muscle hypertrophy. The purpose of the present review was to perform a narrative assessment of the training routines designed for muscle hypertrophy used by bodybuilders. A search was carried out in the databases Pubmed/MEDLINE, Scielo, EBSCO, LILACS, SportDiscus, Web of Science, and CINAHL with the words "Resistance training" and "hypertrophy" in bodybuilders and their variations that involve the respective outcomes. Fourteen studies were identified that investigated the long-term training routines of bodybuilders. These studies demonstrate a pattern in the training organization, whereby there is a separation of training into four distinct periods: off-season, pre-contest, peak week, and post-contest. Each period has a specific spectrum of intensity load, total training volume, and exercise type (multi- or single-joint). We conclude that bodybuilding competitors employed a higher intensity load, lower number of repetitions, and longer rest intervals in the off-season than pre-contest.

The effects of straight and alternating sets on volume load, training efficiency, and metabolic response in grapplers.

BACKGROUND: The importance of strength in Brazilian jiu-jitsu (BJJ) has inspired several recommendations of resistance training (RT) in BJJ athletes, yet little is known about their responses to different RT approaches. Thus, we aimed to investigate volume, efficiency, and fatigue responses in two popular RT protocols. METHODS: In a randomized crossover design, 12 male BJJ athletes (mean age: 24.5±3.1 years; height: 175±5 cm; body mass: 77.1±12.9 kg; body fat: 14.3±5.7%; BMI: 24.8±3.0) completed two separate RT protocols consisting of the same exercises performed either as straight sets (TRAD) or alternating sets (AST) for three sets to failure with a previously established 10-repetition maximum (10RM) load. Maximal number of repetitions (MNR), training duration, volume load (VL), and training efficiency (TE = VL/time), rating of perceived exertion (RPE), and blood lactate concentration (LAC) were assessed in each protocol. RESULTS: MNR decreased steadily from first to last sets for all exercises, with no difference between protocols (P>0.05), resulting in the same VL. The shorter duration of AST resulted in increased TE (P<0.001), which was accompanied by higher RPE (P<0.001) and LAC (P<0.05), as well as higher session perceived load (P<0.01). CONCLUSIONS: Given the role of VL as a driver of RT adaptations, both approaches may be suitable for improvements in strength and hypertrophy. The distinct differences in duration and metabolic response should be considered when implementing RT alongside regular sport training.

Effects of manual resistance training and free weight resistance training on postexercise blood pressure in hypertensive men: a pilot study.

BACKGROUND: Manual resistance training (MRT) is a low cost and practically applicable alternative form of resistance training that is ideal for weight rooms with limited equipment. The aim of this study was to compare the acute and subacute hemodynamic responses between MRT and free weight resistance training (FWRT) in normotensive (NT) and hypertensive (HT) men. METHODS: Twenty-six untrained men performed a single bout of MRT and FWRT with a minimum 72-hour rest in between. Systolic blood pressure (SBP), diastolic blood pressure (DBP), mean blood pressure (MBP) were measured, and double product (DP) was calculated. Variables were assessed at different time points: SBP, DBP and MBP (pre- and 15, 30, 45 and 60 minutes postexercise); DP (half-time and postintervention). RESULTS: The blood pressure values (BP) were greater in HT men in all analyses and interventions. BP responses were similar between MRT and FWRT in both groups of men. In HT men, there was postexercise hypotension (PEH) after 15, 30 and 60 minutes in MBP measured for both interventions. The DP was greater for the MRT intervention, but within the cardiovascular safety limits. CONCLUSIONS: MRT induces PEH in similar levels to FWRT in HT men. Therefore, MRT is a viable and safe alternative for application of FWRT in NT and HT men, reducing the need for expensive equipment.

Influence of Blood Flow Restriction During Low-Intensity Resistance Exercise on the Postexercise Hypotensive Response.

Low-intensity resistance exercise (RE) combined with blood flow restriction (BFR) has been shown to promote similar increases in strength and hypertrophy as traditional high-intensity RE without BFR. However, the effect of BFR on the acute postexercise hypotensive response has received limited examination. Therefore, the purpose of this study was to compare high-intensity exercise (HIE) vs. low-intensity RE with BFR on the postexercise hypotensive response in normotensive young subjects. Fifteen men (age: 23.4 ± 3.4 years) performed the following 2 experimental protocols in randomized order: (a) 3 sets of biceps curls (BCs) at 80% of 1 repetition maximum (RM) and 120-second rest between sets (HIE protocol) and (b) 3 sets of BCs at 40% of 1RM with BFR and 60-second rest between sets. Analysis of systolic blood pressure (SBP) and diastolic blood pressure (DBP) was conducted for 60 minutes after both protocols. The values for SBP, DBP, and mean blood pressure (MBP) at baseline and postexercise were not significantly different between the HIE vs. the BFR protocol. However, within the BFR protocol, significant decreases (p ≤ 0.05) in SBP occurred at 30 minutes (125.86 ± 9.33 mm Hg) and 40 minutes (125.53 ± 10.19 mm Hg) after exercise when compared with baseline (132.86 ± 9.12 mm Hg) and significant decreases in DBP and MBP occurred at 20 minutes, 30 minutes, and 40 minutes after exercise vs. baseline (p ≤ 0.05). Therefore, we conclude that exercises engaging a relatively small amount of muscle mass, such as the BC (or other similar single joint exercises), might be performed at a lower intensity with BFR to promote a postexercise hypotensive response.

Hypotensive effects and performance responses between different resistance training intensities and exercise orders in apparently health women.

To compare the hypotensive effect and performance responses between different resistance training intensities and different exercise orders in apparently healthy women, thirteen apparently healthy women performed four resistance training sessions in randomized order. One group performed the resistance training exercises with 60% of 1RM (SeqA60%): leg press (LG), chest press (CP), leg extension (LE), lat pull down (PD), leg curl (LC) and biceps curl (BC). Another group performed the resistance training exercises with 80% of 1RM (SeqA80%) with the same exercise order. Two other groups performed the resistance training exercises with 60% (SeqB60%) and 80% of 1RM (SeqB80%), however, in another sequence of exercises: CP, PD, BC or LG, LE, LC. The blood pressure was measured before, and at every 15 min until 60 min postexercise. The different intensities and different exercise orders resulted in a significant hypotensive effect in systolic and diastolic blood pressures that remained until 15 min. In addition, significant reductions in systolic blood pressure were observed at 30 min for SeqA in both intensities and for SeqB with intensities of 80% of 1RM. However, there was no significant difference between intensities and different prescription orders (P>0·05). Although the current study showed significant decreases in systolic and diastolic blood pressures after different resistance training sessions, the manipulation of intensity and exercise sequence, such as those used in the present study, was not able to generate significant changes in the duration and magnitude of hypotensive effect.

The Effect of Rest Interval Length on Repetition Consistency and Perceived Exertion During Near Maximal Loaded Bench Press Sets.

The purpose of this study was to compare different rest intervals between sets on repetition consistency and ratings of perceived exertion (RPE) during consecutive bench press sets with an absolute 3RM (3 repetition maximum) load. Sixteen trained men (23.75 ± 4.21 years; 74.63 ± 5.36 kg; 175 ± 4.64 cm; bench press relative strength: 1.44 ± 0.19 kg/kg of body mass) attended 4 randomly ordered sessions during which 5 consecutive sets of the bench press were performed with an absolute 3RM load and 1, 2, 3, or 5 minutes of rest interval between sets. The results indicated that significantly greater bench press repetitions were completed with 2, 3, and 5 minutes vs. 1-minute rest between sets (p ≤ 0.05); no significant differences were noted between the 2, 3, and 5 minutes rest conditions. For the 1-minute rest condition, performance reductions (relative to the first set) were observed commencing with the second set; whereas for the other conditions (2, 3, and 5 minutes rest), performance reductions were not evident until the third and fourth sets. The RPE values before each of the successive sets were significantly greater, commencing with the second set for the 1-minute vs. the 3 and 5 minutes rest conditions. Significant increases were also evident in RPE immediately after each set between the 1 and 5 minutes rest conditions from the second through fifth sets. These findings indicate that when utilizing an absolute 3RM load for the bench press, practitioners may prescribe a time-efficient minimum of 2 minutes rest between sets without significant impairments in repetition performance. However, lower perceived exertion levels may necessitate prescription of a minimum of 3 minutes rest between sets.

Effects of rest interval length on Smith machine bench press performance and perceived exertion in trained men.

This study compared two different rest intervals (RI) between sets of resistance exercise. Ten resistance-trained men (M age = 24.3, SD = 3.5 yr.; M weigh t= 80.0 kg, SD = 15.3; M height = 1.75 m, SD = 0.04) performed five sets of Smith machine bench presses at 60% of one repetition maximum, either with 1.5 min. or 3 min. RI between sets. Their repetition performance, total training volume, velocity, fatigue, rating of perceived exertion, and muscular power were measured. All of these measures indicated that performance was significantly better and fatigue was significantly lower in the 3 min. RI as compared with the 1.5 min. RI, except the rating of perceived exertion which did not show a significant difference. A longer RI between sets promotes superior performance for the bench press.

The effect of rest interval length on multi and single-joint exercise performance and perceived exertion.

The purpose of this study was to compare repetition performance and rating of perceived exertion (RPE) with 1-, 3-, or 5-minute rest intervals between sets of multi and single-joint resistance exercises. Fifteen resistance trained men (23.6 ± 2.64 years, 76.46 ± 7.53 kg, 177 ± 6.98 cm, bench press [BP] relative strength: 1.53 ± 0.25 kg·kg(-1) body mass) completed 12 sessions (4 exercises × 3 rest intervals), with each session involving 5 sets with 10 repetition maximum loads for the free weight BP, machine leg press (LP), machine chest fly (MCF), and machine leg extension (LE) exercises with 1-, 3-, 5-minute rest intervals between sets. The results indicated significantly greater BP repetitions with 3 or 5 minutes vs. 1 minute between sets (p ≤ 0.05); no significant difference was evident between the 3- and 5-minute rest conditions. For the other exercises (i.e., LP, MCF, and LE), significant differences were evident between all rest conditions (1 < 3 < 5; p ≤ 0.05). For all exercises, consistent declines in repetition performance (relative to the first set) were observed for all rest conditions, starting with the second set for the 1-minute condition and the third set for the 3- and 5-minute conditions. Furthermore, significant increases in RPE were evident over successive sets for both the multi and single-joint exercises, with significantly greater values for the 1-minute condition. In conclusion, both multi and single-joint exercises exhibited similar repetition performance patterns and RPE, independent of the rest interval length between sets.

Influence of exercise order on maximum strength and muscle thickness in untrained men.

Traditional exercise order dictates large muscle group or multijoint exercises should be performed before small muscle group or single joint exercises. The purpose of this study was to examine the influence of exercise order on strength and muscle thickness (MT) in untrained men after 12 weeks of linear periodized resistance training. The participants were randomly assigned into three groups. One group began with large and progressed toward small muscle group exercises (LG-SM) while another started with small and advanced to large muscle group exercises (SM-LG). The exercise order for LG-SM was bench press (BP), lat pull-down (LPD), triceps extension (TE), and biceps curl (BC). The order for the SM-LG was BC, TE, LPD, and BP. The third group served as a control group (CG). Training frequency was two sessions/week with at least 72 hours between sessions. One repetition maximum (1RM) for all exercises, biceps and triceps MT (assessed by ultrasound techniques) were collected at baseline and after 12 weeks. After 12 weeks, all exercises for both training groups presented significant 1RM strength gains when compared to CG with exception of BC in LG-SM. Between baseline and post training, all exercises for both training groups presented significant strength gains with exception of BC in LG-SM and BP in SM-LG. Triceps MT for both training groups were significantly higher when compared to the CG, but with no significant differences between them (p > 0.05). Significant differences in MT from pre- to post-training were found only for the SM-LG group (p < 0.05), while the biceps MT presented significant differences only between LG-SM and CG (p < 0.05), Effect size data demonstrated differences in 1RM and triceps MT based on exercise order. In conclusion, if an exercise is important for specific training goals, it should be performed at the beginning of the training session, whether or not it is a large or a small muscle group exercise. Key pointsThe two linear periodized resistance training programs utilized promotes strength and muscle volume gains in untrained men.Exercise order may be particularly important to improve strength during 12 weeks of linear periodized resistance training.If an exercise is important for the training goals of a program, then it should be placed at the beginning of the training session, whether or not it is a large or a small muscle group exercise.