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OBJECTIVE: Using benzodiazepines and certain antidepressants is associated with an increased risk of motor vehicle crashes due to impaired driving skills. Hence, several countries prohibit people who use these drugs from driving. Traffic regulations for driving under the influence of these drugs are, however, largely based on single-dose studies with healthy participants. The effects of drugs on chronic users may be different because of potential development of tolerance or by adapting behavior. In this study, we test the effects of anti-depressants, hypnotics, or anxiolytics use on driving performance in patients who use these drugs for different durations and compare the effects to healthy controls' performance. METHODS: Sixty-six healthy controls and 82 medication users were recruited to perform four drives in a driving simulator. Patients were divided into groups that used anti-depressants, hypnotics, or anxiolytics, for shorter or longer than 3 years (i.e. LT3- or LT3+, respectively). The minimum term of use was 6 months. Driving behavior was measured in terms of longitudinal and lateral control (speed variability and Standard Deviation of Lateral Position: SDLP), brake reaction time, and time headway. Impaired driving performance was defined as performing similar to driving with a Blood Alcohol Concentration of 0.5 or higher, determined by means of non-inferiority analyses. RESULTS: Reaction time analyses revealed inconclusive findings in all groups. No significant performance differences between matched healthy controls, LT3- (n = 2), and LT3+ (n = 8) anxiolytics users were found. LT3+ antidepressants users (n = 12) did not perform inferior to their matched controls in terms of SDLP. LT3- hypnotics users (n = 6) showed more speed variability than their matched healthy controls, while this effect was not found for the LT3+ group (n = 14): the latter did not perform inferior to the healthy controls. Regarding Time Headway, no conclusions about the LT3- hypnotics group could be drawn, while the LT3+ group did not perform inferior compared to the control group. CONCLUSIONS: The small number of anxiolytics users prohibits drawing conclusions about clinical relevance. Although many outcomes were inconclusive, there is evidence that some elements of complex driving performance may not be impaired (anymore) after using antidepressants or hypnotics longer than 3 years.
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The goal of this on the road driving study was to investigate how drivers adapt their behavior when driving with conditional vehicle automation (SAE L3) on different occasions. Specifically, we focused on changes in how fast drivers took over control from automation and how their gaze off the road changed over time. On each of three consecutive days, 21 participants drove for 50 min, in a conditionally automated vehicle (Wizard of Oz methodology), on a typical German commuting highway. Over these rides the take-over behavior and gaze behavior were analyzed. The data show that drivers' reactions to non-critical, system initiated, take-overs took about 5.62 s and did not change within individual rides, but on average became 0.72 s faster over the three rides. After these self-paced take-over requests a final urgent take-over request was issued at the end of the third ride. In this scenario participants took over rapidly with an average of 5.28 s. This urgent take-over time was not found to be different from the self-paced take-over requests in the same ride. Regarding gaze behavior, participants' overall longest glance off the road and the percentage of time looked off the road increased within each ride, but stayed stable over the three rides. Taken together, our results suggest that drivers regularly leave the loop by gazing off the road, but multiple exposures to take-over situations in automated driving allow drivers to come back into loop faster.
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Accidentes de Tránsito , Conducción de Automóvil , Humanos , Accidentes de Tránsito/prevención & control , Tiempo de Reacción , Automatización , Vehículos AutónomosRESUMEN
In the current study we investigated if drivers of conditionally automated vehicles can be kept in the loop through lane change maneuvers. More specifically, we examined whether involving drivers in lane-changes during a conditionally automated ride can influence critical take-over behavior and keep drivers' gaze on the road. In a repeated measures driving simulator study (n = 85), drivers drove the same route three times, each trial containing four lane changes that were all either (1) automated, (2) semi-automated or (3) manual. Each ride ended with a critical take-over situation that could be solved by braking and/or steering. Critical take-over reactions were analyzed with a linear mixed model and parametric accelerated failure time survival analysis. As expected, semi-automated and manual lane changes throughout the ride led to 13.5% and 17.0% faster maximum deceleration compared to automated lane changes. Additionally, semi-automated and manual lane changes improved the quality of the take-over by significantly decreasing standard deviation of the steering wheel angle. Unexpectedly, drivers in the semi-automated condition were slowest to start the braking maneuver. This may have been caused by the drivers' confusion as to how the semi-automated system would react. Additionally, the percentage gaze off-the-road was significantly decreased by the semi-automated (6.0%) and manual (6.6%) lane changes. Taken together, the results suggest that semi-automated and manual transitions may be an alarm-free instrument which developers could use to help maintain drivers' perception-action loop and improve automated driving safety.
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Accidentes de Tránsito , Conducción de Automóvil , Accidentes de Tránsito/prevención & control , Automatización , Humanos , Equipos de Seguridad , Tiempo de ReacciónRESUMEN
Since Alzheimer's disease may affect driving performance, patients with Alzheimer's disease are assessed on fitness to drive. On-road driving assessments are widely used, and attempts have also been made to develop strategies to assess fitness to drive in a clinical setting. Preferably, a first indication of fitness to drive is obtained quickly after diagnosis using a single test such as the Mini-Mental State Examination (MMSE). The aim of this study is to investigate whether the MMSE can be used to predict whether patients with Alzheimer's disease will pass or fail an on-road driving assessment. Patients with Alzheimer's disease (n = 81) participated in a comprehensive fitness-to-drive assessment which included the MMSE as well as an on-road driving assessment [PLoS One 11(2):e0149566, 2016]. MMSE cutoffs were applied as suggested by Versijpt and colleagues [Acta Neurol Belg 117(4):811-819, 2017]. All patients with Alzheimer's disease who scored below the lower cutoff (MMSE ≤ 19) failed the on-road driving assessment. However, a third of the patients with Alzheimer's disease who scored above the upper cutoff (MMSE ≥ 25) failed the on-road driving assessment as well. We conclude that the MMSE alone has insufficient predictive value to correctly identify fitness to drive in patients with very mild-to-mild Alzheimer's disease implicating the need for comprehensive assessments to determine fitness to drive in a clinical setting.
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Enfermedad de Alzheimer/psicología , Conducción de Automóvil/psicología , Anciano , Anciano de 80 o más Años , Enfermedad de Alzheimer/diagnóstico , Femenino , Humanos , Masculino , Pruebas de Estado Mental y Demencia , Persona de Mediana Edad , Índice de Severidad de la EnfermedadRESUMEN
BACKGROUND: Stroke/death rates within 30 days of carotid endarterectomy (CEA) and carotid artery stenting (CAS) in RCTs inform current clinical guidelines. However, the risks may have changed in recent years with wider use of effective stroke prevention therapies, especially statins, improved patient selection and growing operator expertise. The aim of this study was to investigate whether the procedural stroke/death risks from CEA and CAS have changed over time. METHODS: MEDLINE and Embase were searched systematically from inception to May 2016 for observational cohort studies of CEA and CAS. Studies included reported on more than 1000 patients, with 30-day outcomes after the procedure according to patients' symptom status (recent stroke or transient ischaemic attack). Restricted maximum likelihood random-effects and meta-regressions methods were used to synthesize procedural stroke/death rates of CEA and CAS according to year of study recruitment completion. RESULTS: Fifty-one studies, including 223 313 patients undergoing CEA and 72 961 undergoing CAS, were reviewed. Procedural stroke/death risks of CEA decreased over time in symptomatic and asymptomatic patients. Risks were substantially lower in studies completing recruitment in 2005 or later, both in symptomatic (5·11 per cent before 2005 versus 2·68 per cent from 2005 onwards; P = 0·002) and asymptomatic (3·17 versus 1·50 per cent; P < 0·001) patients. Procedural stroke/death rates of CAS did not change significantly over time (4·77 per cent among symptomatic and 2·59 per cent among asymptomatic patients). There was substantial heterogeneity in event rates and recruitment periods were long. CONCLUSIONS: Risks of procedural stroke/death following CEA appear to have decreased substantially. There was no evidence of a change in stroke/death rates following CAS.
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Estenosis Carotídea/cirugía , Endarterectomía Carotidea , Complicaciones Posoperatorias , Stents , Accidente Cerebrovascular/etiología , Endarterectomía Carotidea/efectos adversos , Endarterectomía Carotidea/mortalidad , Humanos , Modelos Estadísticos , Complicaciones Posoperatorias/epidemiología , Riesgo , Stents/efectos adversos , Accidente Cerebrovascular/epidemiología , Resultado del TratamientoRESUMEN
INTRODUCTION: In patients with carotid stenosis receiving medical treatment, carotid plaque echolucency has been thought to predict risk of future stroke and of other cardiovascular events. This study evaluated the prognostic value of pre-operative plaque echolucency for future stroke and cardiovascular death in patients undergoing carotid endarterectomy in the first Asymptomatic Carotid Surgery Trial (ACST-1). METHODS: In ACST-1, 1832/3120 patients underwent carotid endarterectomy (CEA), of whom 894 had visual echolucency assessment according to the Gray-Weale classification. During follow-up patients were monitored both for peri-procedural (i.e. within 30 days) death, stroke, or MI, and for long-term risk of stroke or cardiovascular death. Unconditional maximum likelihood estimation was used to calculate odds ratios of peri-procedural risk and Kaplan-Meier statistics with log-rank test were used to compare cumulative long-term risks. RESULTS: Of 894 operated patients in whom echolucency was assessed, 458 plaques (51%) were rated as echolucent and peri-procedural risk of death/stroke/MI in these patients was non-significantly higher when compared with patients with non-echolucent plaques (OR 1.48 [95% CI 0.76-2.88], p = .241). No differences were found in the 10 year risk of any stroke (30/447 [11.6%] vs. 29/433 [11.0%], p = .900) or cardiovascular (non-stroke) death (85/447 [27.9%] vs. 93/433 [32.1%], p = .301). CONCLUSION: In ACST-1, carotid plaque echolucency assessment in patients undergoing CEA offered no predictive value with regard to peri-operative or long-term stroke risk or of cardiovascular (non-stroke) death.
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Arterias Carótidas/cirugía , Estenosis Carotídea/cirugía , Endarterectomía Carotidea/efectos adversos , Placa Aterosclerótica , Accidente Cerebrovascular/etiología , Ultrasonografía , Anciano , Enfermedades Asintomáticas , Arterias Carótidas/diagnóstico por imagen , Estenosis Carotídea/complicaciones , Estenosis Carotídea/diagnóstico por imagen , Estenosis Carotídea/mortalidad , Distribución de Chi-Cuadrado , Endarterectomía Carotidea/mortalidad , Femenino , Humanos , Estimación de Kaplan-Meier , Masculino , Persona de Mediana Edad , Infarto del Miocardio/etiología , Oportunidad Relativa , Valor Predictivo de las Pruebas , Medición de Riesgo , Factores de Riesgo , Accidente Cerebrovascular/diagnóstico , Accidente Cerebrovascular/mortalidad , Factores de Tiempo , Resultado del TratamientoRESUMEN
OBJECTIVE/BACKGROUND: Carotid endarterectomy (CEA) prevents future stroke, but this benefit depends on detection and control of high peri-operative risk factors. In symptomatic patients, diastolic hypertension has been causally related to procedural stroke following CEA. The aim was to identify risk factors causing peri-procedural stroke in asymptomatic patients and to relate these to timing of surgery and mechanism of stroke. METHODS: In the first Asymptomatic Carotid Surgery Trial (ACST-1), 3,120 patients with severe asymptomatic carotid stenosis were randomly assigned to CEA plus medical therapy or to medical therapy alone. In 1,425 patients having their allocated surgery, baseline patient characteristics were analysed to identify factors associated with peri-procedural (< 30 days) stroke or death. Multivariate analysis was performed on risk factors with a p value < .3 from univariate analysis. Event timing and mechanism of stroke were analysed using chi-square tests. RESULTS: A total of 36 strokes (27 ischaemic, four haemorrhagic, five unknown type) and six other deaths occurred during the peri-procedural period, resulting in a stroke/death rate of 2.9% (42/1,425). Diastolic blood pressure at randomisation was the only significant risk factor in univariate analysis (odds ratio [OR] 1.34 per 10 mmHg, 95% confidence interval [CI] 1.04-1.72; p = .02) and this remained so in multivariate analysis when corrected for sex, age, lipid lowering therapy, and prior infarcts or symptoms (OR 1.34, 95% CI 1.05-1.72; p = .02). In patients with diastolic hypertension (> 90 mmHg) most strokes occurred during the procedure (67% vs. 20%; p = .02). CONCLUSION: In ACST-1, diastolic blood pressure was the only independent risk factor associated with peri-procedural stroke or death. While the underlying mechanisms of the association between lower diastolic blood pressure and peri-procedural risk remain unclear, good pre-operative control of blood pressure may improve procedural outcome of carotid surgery in asymptomatic patients.
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Presión Sanguínea , Estenosis Carotídea/cirugía , Endarterectomía Carotidea/efectos adversos , Hipertensión/fisiopatología , Accidente Cerebrovascular/etiología , Anciano , Enfermedades Asintomáticas , Estenosis Carotídea/diagnóstico por imagen , Estenosis Carotídea/mortalidad , Estenosis Carotídea/fisiopatología , Distribución de Chi-Cuadrado , Endarterectomía Carotidea/mortalidad , Femenino , Humanos , Hipertensión/diagnóstico , Hipertensión/mortalidad , Modelos Logísticos , Masculino , Persona de Mediana Edad , Análisis Multivariante , Oportunidad Relativa , Embarazo , Medición de Riesgo , Factores de Riesgo , Índice de Severidad de la Enfermedad , Accidente Cerebrovascular/diagnóstico , Accidente Cerebrovascular/mortalidad , Accidente Cerebrovascular/fisiopatología , Factores de Tiempo , Resultado del TratamientoRESUMEN
OBJECTIVE/BACKGROUND: Several plaque and lesion characteristics have been associated with an increased risk for procedural stroke during or shortly after carotid artery stenting (CAS). While technical advancements in stent design and cerebral protection devices (CPD) may help reduce the procedural stroke risk, and anatomy remains important, tailoring stenting procedures according to plaque and lesion characteristics might be a useful strategy in reducing stroke associated with CAS. In this descriptive report of the ongoing Asymptomatic Carotid Surgery Trial-2 (ACST-2), it was assessed whether choice for stent and use or type of CPD was influenced by plaque and lesion characteristics. METHODS: Trial patients who underwent CAS between 2008 and 2015 were included in this study. Chi-square statistics were used to study the effects of plaque echolucency, ipsilateral preocclusive disease (90-99%), and contralateral high-grade stenosis (>50%) or occlusion of the carotid artery on interventionalists' choice for stent and CPD. Differences in treatment preference between specialties were also analysed. RESULTS: In this study, 831 patients from 88 ACST-2 centres were included. Almost all procedures were performed by either interventional radiologists (50%) or vascular surgeons (45%). Plaque echolucency, ipsilateral preocclusive disease (90-99%), and significant contralateral stenosis (>50%) or occlusion did not affect the choice of stent or either the use of cerebral protection and type of CPD employed (i.e., filter/flow reversal). Vascular surgeons used a CPD significantly more often than interventional radiologists (98.6% vs. 76.3%; p < .001), but this choice did not appear to be dependent on patient characteristics. CONCLUSION: In ACST-2, plaque characteristics and severity of stenosis did not primarily determine interventionalists' choice of stent or use or type of CPD, suggesting that other factors, such as vascular anatomy or personal and centre preference, may be more important. Stent and CPD use was highly heterogeneous among participating European centres.
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Estenosis Carotídea/terapia , Circulación Cerebrovascular , Trastornos Cerebrovasculares/prevención & control , Dispositivos de Protección Embólica , Procedimientos Endovasculares/instrumentación , Stents , Enfermedades Asintomáticas , Estenosis Carotídea/complicaciones , Estenosis Carotídea/diagnóstico por imagen , Estenosis Carotídea/fisiopatología , Trastornos Cerebrovasculares/diagnóstico , Trastornos Cerebrovasculares/etiología , Trastornos Cerebrovasculares/fisiopatología , Distribución de Chi-Cuadrado , Toma de Decisiones Clínicas , Endarterectomía Carotidea , Procedimientos Endovasculares/efectos adversos , Humanos , Selección de Paciente , Placa Aterosclerótica , Pautas de la Práctica en Medicina , Diseño de Prótesis , Factores de Riesgo , Índice de Severidad de la Enfermedad , Factores de Tiempo , Resultado del TratamientoRESUMEN
RATIONALE: The driving simulator provides a safe and controlled environment for testing driving behaviour efficiently. The question is whether it is sensitive to detect drug-induced effects. OBJECTIVE: The primary aim of the current study was to investigate the sensitivity of the driving simulator for detecting drug effects. As a case in point, we investigated the dose-related effects of oral ∆(9)-tetrahydrocannabinol (THC), i.e. dronabinol, on simulator and on-the-road driving performance in equally demanding driving tasks. METHOD: Twenty-four experienced driver participants were treated with dronabinol (Marinol®; 10 and 20 mg) and placebo. Dose-related effects of the drug on the ability to keep a vehicle in lane (weaving) and to follow the speed changes of a lead car (car following) were compared within subjects for on-the-road versus in-simulator driving. Additionally, the outcomes of equivalence testing to alcohol-induced effects were investigated. RESULTS: Treatment effects found on weaving when driving in the simulator were comparable to treatment effects found when driving on the road. The effect after 10 mg dronabinol was however less strong in the simulator than on the road and inter-individual variance seemed higher in the simulator. There was, however, a differential treatment effect of dronabinol on reactions to speed changes of a lead car (car following) when driving on the road versus when driving in the simulator. CONCLUSION: The driving simulator was proven to be sensitive for demonstrating dronabinol-induced effects particularly at higher doses. Treatment effects of dronabinol on weaving were comparable with driving on the road but inter-individual variability seemed higher in the simulator than on the road which may have potential effects on the clinical inferences made from simulator driving. Car following on the road and in the simulator were, however, not comparable.
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Conducción de Automóvil , Agonistas de Receptores de Cannabinoides/farmacología , Dronabinol/farmacología , Desempeño Psicomotor/efectos de los fármacos , Adulto , Estudios Cruzados , Método Doble Ciego , Femenino , Humanos , Masculino , Interfaz Usuario-Computador , Adulto JovenRESUMEN
In a recent study published in Accident Analysis & Prevention, Vansteenkiste et al. (2013)--as one of the first in this field--investigated the visual control of bicycle steering. They undertook the interesting task of testing cyclists' eye fixation behaviour against Donges' two-level model of steering, i.e. the guidance level to anticipate alternations in the course of the road and the stabilization level for lane keeping. Although the laboratory experiment itself is well conducted, we believe that its results cannot be used to test the two-level model of steering as developed for driving. The test track was only 15m long, was completely straight and was known in advance. Accordingly, it did not provide adequate conditions for testing the guidance level. Furthermore, as the experimental lanes were much narrower than real-world cycling lanes, the stabilization level differed considerably from that in the real world. The study by Vansteenkiste et al. (2013) may provide valuable insight into the role of vision in 'precision steering', but, as we discuss in the paper, more elaborate research paradigms are needed to achieve more comprehensive knowledge of the role of vision in real-world cycling and cycling safety.
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Ciclismo/psicología , Desempeño Psicomotor , Femenino , Humanos , MasculinoRESUMEN
When measuring operator states the predictive power of cardiovascular and respiratory measures in relation to mental workload has been questioned. One of the main questions is to what extent do cardiovascular measures actually reflect mental workload. This question arises because good measures of mental workload should be sensitive to changes in mental effort alone and not to other influences or at least the changes associated with mental workload should be easy to isolate. In the case of cardiovascular measures, the physiological change brought on by the baroreflex is a compensatory control effect that can potentially overshadow changes in physiology due to mental effort and therefore reduce the usefulness of cardiovascular measures. However, this does not need to be the case. Despite the effects caused by the baroreflex differences in heart rate, heart rate variability and other cardiovascular measures associated with task related effort can still be found using short-term response patterns. The short-segment analysis approach described in this paper is based on a time-frequency method in which the spectral power of the cardiovascular measures in specified spectral bands is computed from small time segments, i.e. 30 s. To demonstrate the effectiveness of this technique two studies which made use of a simulation of an ambulance dispatcher's task are described, both with easy and difficult task conditions. A short-lasting increase in task demand was found to be reflected in short-lasting increases in heart rate and blood pressure in combination with corresponding decreases in heart rate variability and blood pressure variability. These effects were larger in easy task conditions than in hard conditions, likely due to a higher overall effort-level during the hard task conditions. However, the developed measures are still very sensitive to mental effort and if this brief segmentation approach is used cardiovascular measures show promise as good candidates for reflecting mental effort during the assessment of operator state.
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Barorreflejo/fisiología , Presión Sanguínea/fisiología , Frecuencia Cardíaca/fisiología , Carga de Trabajo , Adulto , Ambulancias , Simulación por Computador , Electrocardiografía , Femenino , Humanos , Masculino , Análisis Espectral , Adulto JovenRESUMEN
INTRODUCTION: In the Netherlands, a survey was set up to monitor the extent of the use of portable, electronic devices while cycling amongst different age groups of cyclists and to estimate the possible consequences for safety. METHOD: The main research questions concerned age differences in the self-reported use of electronic devices while cycling, self-reported crash involvement and risk, and self-reported compensatory behaviour. Teen cyclists (12-17 years) and young adult cyclists (18-34 years) were more frequent users, and also more indiscriminate users of portable devices while cycling than middle-aged and older adult cyclists (35-49 years; 50+ years). RESULTS: After statistical correction for influences on crash risk of urbanization level, weekly time spent cycling, and cycling in more demanding traffic situations, the odds of being involved in a bicycle crash were estimated to be higher for teen cyclists and young adult cyclists who used electronic devices on every trip compared to same age groups cyclists who never used these devices. For middle-aged and older adult cyclists, the use of portable electronic devices was not a significant predictor of bicycle crashes, but frequency of cycling in demanding traffic situations was. Possible implications for education or legal measures are discussed. IMPACT ON INDUSTRY: Results may inform researchers, policy makers, and cyclists themselves. Educational campaigns may use risk information to warn young cyclists about risk of device use while cycling.
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Ciclismo/lesiones , Teléfono Celular , Electrónica , Reproductor MP3 , Adolescente , Adulto , Anciano , Niño , Femenino , Humanos , Modelos Logísticos , Masculino , Persona de Mediana Edad , Países Bajos , Factores de Riesgo , Seguridad , Encuestas y CuestionariosRESUMEN
A considerable amount of all traffic accidents can be attributed to driving under the influence of alcohol. In particular the group of drivers aged 18-24 years is involved in many serious traffic accidents where alcohol turns out to be a major factor. In fact this age group shows about three times as many alcohol related traffic fatalities as all other categories of road users. The intervention program "Alcohol-free on the road" (Dutch: "Alcoholvrij op weg") aims to enhance young people's awareness of the effects of alcohol by letting them personally experience the effect of alcohol on their driving abilities. To this end, young drivers were invited to a closed circuit and allowed to drive first sober and then intoxicated, guided and guarded by driving instructors. Based on several other studies it was thought that a realistic experience of the effects of alcohol on driving abilities may contribute to a better understanding of the impact of alcohol and may stimulate attitudes that are needed to support the conscious decision not to drive while intoxicated. After more than ten years of running and data collection, 1200 young drivers have participated in the intervention program. In a quasi-experimental study with a non-equivalent group design, the program is evaluated in order to assess its effectiveness both with respect to the attitudes of the participants and the actual relevant behaviour in the years after the alcohol experience intervention program they attended, i.e. the incidence of actually driving under the influence of alcohol. To do this, a questionnaire was sent to a subset (415) of the participants who have completed the program, along with a control group (450), to compare attitudes and actual behaviour. In addition, the Public Prosecutor checked the files of those who responded, for the occurrence of driving under the influence of alcohol. The group that participated in the alcohol intervention program showed more awareness about the dangers of driving while intoxicated than the control group, and this group reported improved alcohol law compliance. Furthermore, less participants in the intervention program than in the control group were present in the Public Prosecutor files, respectively 0.7% and 4.2%. Hence, the alcohol driving experience intervention program might turn out to be effective and successful in decreasing driving under the influence of alcohol. Although the results of the present study are no more than suggestive, they may be considered a first step towards demonstrating the effectiveness of this type of intervention. However, the intervention is unique and warrants a more robust evaluation. A large-sized randomized controlled trial should be conducted in the next phase to confirm the findings that the intervention program is a suitable educational tool to decrease driving under the influence of alcohol. The present paper serves to raise awareness of this intervention and its potential.
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Accidentes de Tránsito/mortalidad , Accidentes de Tránsito/prevención & control , Conducción de Automóvil/legislación & jurisprudencia , Aplicación de la Ley , Concesión de Licencias/legislación & jurisprudencia , Seguridad/legislación & jurisprudencia , Intoxicación Alcohólica/complicaciones , Intoxicación Alcohólica/prevención & control , Causas de Muerte , Humanos , España , Trastornos Relacionados con Sustancias/complicaciones , Trastornos Relacionados con Sustancias/prevención & controlRESUMEN
Adaptive support has the potential to keep the operator optimally motivated, involved, and able to perform a task. In order to use such support, the operator's state has to be determined from physiological parameters and task performance measures. In an environment where the task of an ambulance dispatcher was simulated, two studies have been carried out to evaluate the feasibility of using cardiovascular measures for adaptive support. During performance of this 2-3h lasting planning task, a pattern of results is found that can be characterized by an initial increase of blood pressure and heart rate and a decrease of heart rate variability (defense reaction pattern) followed by an ongoing increase of blood pressure counteracted by a decrease in heart rate. This pattern can be explained by an augmented short-term blood pressure control (baroreflex), which is reflected in an increase of baroreflex sensitivity. Additionally, in this latter phase heart rate variability (HRV) increases as a function of time, while blood pressure variability decreases. In the two studies performed, the baroreflex pattern was consistent for all the relevant variables. In both studies there were periods with high and low workload. Effects of task load are mainly reflected in the variability measures, while in the second study, additionally, blood pressure level was higher during periods with high task demands. The conclusion of the studies is that consistent cardiovascular response patterns can be recognized during this semi-realistic planning task, where variability measures are most sensitive to task demand changes, while blood pressure and baroreflex sensitivity are most informative with respect to cardiovascular state changes. These findings can be seen as a great potential benefit for future use in adaptive support applications.
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Adaptación Psicológica , Ambulancias , Sistema Cardiovascular , Electrocardiografía , Adulto , Presión Sanguínea , Electrodos , Servicios Médicos de Urgencia , Femenino , Humanos , MasculinoRESUMEN
Most traffic accidents can be attributed to driver impairment, e.g. inattention, fatigue, intoxication, etc. It is now technically feasible to monitor and diagnose driver behaviour with respect to impairment with the aid of a limited number of in-vehicle sensors. However, a valid framework for the evaluation of driver impairment is still lacking. To provide an acceptable definition of driver impairment, a method to assess absolute and relative criteria was proposed to fulfil the paradoxical goal of defining impaired driving which is consistent yet adaptable to interindividual differences.
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Accidentes de Tránsito/prevención & control , Conducción de Automóvil/normas , Evaluación de la Discapacidad , Intoxicación Alcohólica/diagnóstico , Algoritmos , Conducción de Automóvil/psicología , Benchmarking , Humanos , Redes Neurales de la Computación , Observación , Examen Físico , Gestión de Riesgos , Administración de la Seguridad , Estados Unidos , Trastornos de la Visión/diagnósticoRESUMEN
When driving on lower-category Dutch rural roads without any delineation, drivers are likely to drift off the road with their right-side wheels, thus incurring damage to the pavement edge or even leading to accidents. In two experiments, two types of road-edge delineation, with continuous or dashed edge lines, were compared with two control roads without lines or with only a dashed line on the road axis. The first experiment consisted of non-obtrusive video recordings of passing traffic. Vehicle position on the experimental roads was more to the road's centre than on the control roads. The second experiment was a driving test with an instrumented vehicle, during daytime lighting and during darkness. Again, vehicle lateral position was more central on the experimental roads, especially during darkness. Subjects could safely pass oncoming vehicles. Driving speed increased on the experimental roads compared with the unlined control road, but not beyond speeds found on the axis-lined control road. Driver's mental effort while driving over the experimental roads did not differ from the effort while driving over the control roads. Subjectively rated effort was higher for the unlined control road than for the three other roads. Subjects preferred the edge-lined roads to the unlined control road, but not more than the axis-lined control road. It was concluded that edge-lines may provide a simple and effective way of inducing a more favourable lateral position on rural roads without having negative effects on subjective appraisal, driving performance or mental workload.
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Conducción de Automóvil , Ergonomía , Humanos , Población Rural , Análisis y Desempeño de Tareas , Grabación en VideoRESUMEN
Three experiments are presented in which the accuracy of different methods to approximate time-to-line crossing is assessed the first experiment TLC was computed, using a trigonometric method, during normal driving while the vehicle stayed in lane. The minima of TLC were compared with two approximations and it was found computing TLC as lateral distance divided by lateral velocity gave poor results. It was concluded that this simple approximation is not suitable for measuring TLC minima in studies of driver behaviour. A way of computing TLC that takes account of the curved path of the vehicle resulted in a good fit of TLC minima. In two other experiments the vehicle exceeded the lane boundary, either intentionally as a result of a lane change manoeuvre, or unintentionally as a result of impaired driving. In these cases no TLC minima exists since these only occur as a result of correcting steering actions to stay within the lane. In contrast to normal lane keeping, it was found that prior to crossing the lane boundary, the simple approximation resulted in more accurate estimation of available time before the lane boundary is exceeded compared to the more complex approximation. This indicates that for lane keeping support systems and systems that detect when the driver has fallen asleep and drifts out of lane, a simple algorithm for TLC estimation may give reliable results, while this algorithm is not accurate enough for more fundamental studies of driver behaviour. However, the reliability of the approximation is only satisfactory over a very short time range before the lane boundary is actual exceeded. This may result in warnings that come too late and result in too little time to respond for the driver.
Asunto(s)
Accidentes de Tránsito/prevención & control , Conducción de Automóvil/psicología , Modelos Psicológicos , Adulto , Anciano , Anciano de 80 o más Años , Algoritmos , Femenino , Humanos , Masculino , Persona de Mediana Edad , Países Bajos , Análisis de Regresión , Reproducibilidad de los Resultados , Fases del Sueño , Factores de TiempoRESUMEN
A system that contrasts driver behaviour with normative behaviour was tested in an advanced driving simulator. Drivers were provided with auditory and visual tutoring messages if deviations were detected from normative, i.e. legally allowed behaviour with respect to a selection of offences. Results showed that the system was very effective in increasing law-abiding behaviour, which has a major positive effect on traffic safety. However, driver mental effort, as indicated by self-reports and drivers' physiological states, was slightly increased in conditions where drivers received feedback. Opinion about the tutoring system was positive in terms of usefulness. Self-reports on satisfaction differed between age groups; young drivers rated it low, while elderly drivers held a positive attitude.