Serum bilirubin levels in newborns of diabetic and hypertensive mothers.

PIP: The aim of this study was to investigate the effect of oxytocin induction and augmentation on neonatal bilirubin levels in newborns of diabetic and hypertensive mothers. All women included in the study were admitted to the obstetrics department at Al Hussein Hospital. They were 18-38 years old, and their gestational ages were 38-41 weeks by date. A total number of 140 newborn infants were divided into 3 groups and studied for bilirubin levels. The first group consisted of 40 infants of diabetic mothers, 20 of whom were given oxytocin for labor induction and 20 of whom received it for labor augmentation. The second group consisted of 40 infants of hypertensive mothers, 20 of whom were given oxytocin for labor induction and 20 of whom received it for labor augmentation. The third group consisted of 60 controls, 20 of whom were given oxytocin for labor induction, 20 of whom received it for labor augmentation, and 20 of whom received no oxytocin. It was found that total and unconjugated bilirubin levels were higher in infants delivered after induction of labor, whether their mothers were diabetic, hypertensive, or neither, than in infants delivered without labor induction. Bilirubin levels were mildly high in infants of diabetic mothers after augmented delivery and then nullified after 24 hours. However, the study suggested that the increased bilirubin levels were related to induced labor rather than the medical problem of the mothers, provided that the newborns were of average weight.^ieng

Prolactin imbalance as a result of bilharzial hepatosplenomegaly.

Prolactin is an important hormone for maintenance of normal sexual life in human. Prolactin is produced in the lactotropic cells in the lateral wing of the anterior pituitary gland. Prolactin imbalance associated with bilharzial hepatosplenomegaly with subsequent infertility was carried out on sixty female patients and 30 normal controls. In bilharzial patients and 30 normal controls. In bilharzial patients with hepatosplenomegaly, there was hyperprolactinaemia in 13.33% of cases. 10% of patients suffering from bilharzial hepatosplenomegaly had primary infertility and 70% had secondary infertility more than 5 years. Galactorrhea was present in 10% of cases with bilharzial hepatosplenomegaly. There was irreversible relationship between the duration of bilharzial infection and serum prolactin level and inability to conceive, and also between the duration of bilharzial infection and endocrine manifestations as infrequency and irregularity of menstruation.

Incidence of anovulation in cyclic menstruating infertile women.

PIP: This study aimed to estimate the incidence of anovulation in menstruating, infertile women. The study was conducted during January-June 1986 at the infertility clinic of El Hussein University Hospital. 123 menstruating, infertile women, 20-35 years old, were the subjects of this study. 68 cases were primary infertility and 55 cases were secondary infertility. An endometrial biopsy was taken during the five days prior to menstruation, and endometrial data were statistically analyzed and compared. The total incidence of anovulation in the studied group was 30%. Incidence of anovulation was 41.18% in primary infertile women and 16.36% in secondary infertile women. It was also found that the incidence of anovulation increased with the delay of age of menarche. Luteal phase defect was reported in 25% of cases. It was concluded that a fairly recognizable incidence of anovulation and luteal phase defect occurred with secondary infertility. Hence, detection of ovulation in secondary infertile women with regular menstruation is considered a mandatory step in managing these women.^ieng