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1.
Theory Decis ; 96(4): 517-553, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38752153

RESUMEN

We consider a group of receivers who share a common prior on a finite state space and who observe private correlated messages that are contingent on the true state of the world. Our focus lies on the beliefs of receivers induced via the signal chosen by the sender and we provide a comprehensive analysis of the inducible distributions of posterior beliefs. Classifying signals as minimal, individually minimal, and language-independent, we show that any inducible distribution can be induced by a language-independent signal. We investigate the role of the different classes of signals for the amount of higher order information that is revealed to receivers. The least informative signals that induce a fixed distribution over posterior belief profiles lie in the relative interior of the set of all language-independent signals inducing that distribution.

2.
Data Brief ; 49: 109307, 2023 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-37346929

RESUMEN

Developing complex software may be difficult for students or those with less technical expertise in software design due to the large number of diagrams and the complexity of their relationships. Unified modeling language (UML) provides conceptual software design as a system's blueprints, including programming statements, software processes, software components, deployment, design, and development, whereas database schemas use UML for an object-oriented database and entity relation model (ERD) for a relational database. An information flow diagram (IFD) is a technical tool for designing software that includes Infrastructure, data and information, and processing flow. IFD can benefit from examining a new paradigm that facilitates a more practical and rapid understanding of information designs. This data set contains the results of an investigation into the factors affecting the acceptance of IFD for software design by college students. Google forms are used to collect information from undergraduate and graduate computer science, IT, and software engineering students. The extended technology acceptance model (TAM) will focus on studying factors affecting acceptance or decision to use IFD, which includes the ability to create information flow diagrams, satisfaction with software design, and business requirement expectations. This study was carried out at four Thai universities. Research data collection for software design and development courses spanned the academic year 2021. Concerning the use of IFD in software design, 537 respondents were questioned regarding their perceptions, behavioral intentions, information flow diagram capability, software design satisfaction, and business requirement expectations. All students completed the survey. To ensure that participation was voluntary, each participant gave informed consent. Any collected information was rendered anonymous. The participants were given the information solely for research purposes. Ethical values, respect, autonomy, compassion, and confidentiality were guaranteed. The survey's primary questions correspond to the acceptance model's independent variables. Online distribution of the questionnaire yielded 537 valid responses. The dataset consists of 1) student demographics and 2) student perspectives on the factors influencing their intent to learn and apply IFD to software design. Partial Least Squares - Structural Equation Modelling was utilized to analyze the data (PLS-SEM). With the help of these data, researchers, software developers, and educators in various settings can use and analyze alternative software designs and validate models used to study and predict the acceptance of behaviors and factors.

3.
Artículo en Inglés | MEDLINE | ID: mdl-36361077

RESUMEN

As the fourth pillar of sustainable development, culture is widely recognized as contributing to human wellbeing. The distinctive culture of cities is an important driving force for attracting visitors to destinations for tourism consumption. Since historical cities have important cultural and historical values, the design of their tourist maps needs not only geographic positioning and artistic aesthetics, but also a systematic design method to present the connotation of regional cultures, so as to enhance the local cultural identity of hosts and the cultural cognition of visitors, and to drive the local tourism economy, improve the regional environment, promote cultural transmission and inheritance with the help of tourist map design in terms of cultural sustainability, which ultimately achieves sustainable development of human wellbeing. Taking Foshan, a national historical city, as an example, combined with the cultural gene and the cultural hierarchy theory, this study analyzes and summarizes the regional culture of Foshan from three aspects: material cultural gene, intangible cultural gene and spiritual cultural gene. This study also comprehensively presents the geographical information and historical or humanistic characteristics of the city through direct translation, narrative translation, and metaphor translation, which provide theoretical support and practical guidance for the integration of regional cultures into tourist map design.


Asunto(s)
Desarrollo Sostenible , Viaje , Humanos , China , Turismo , Ciudades
4.
Clin Chem Lab Med ; 60(9): 1356-1364, 2022 08 26.
Artículo en Inglés | MEDLINE | ID: mdl-35696446

RESUMEN

OBJECTIVES: Although laboratory result presentation may lead to information overload and subsequent missed or delayed diagnosis, little has been done in the past to improve this post-analytical issue. We aimed to investigate the efficiency, efficacy and user satisfaction of alternative report formats. METHODS: We redesigned cumulative (sparkline format) and single reports (improved tabular and z-log format) and tested these on 46 physicians, nurses and medical students in comparison to the classical tabular formats, by asking standardized questions on general items on the reports as well as on suspected diagnosis and follow-up treatment or diagnostics. RESULTS: Efficacy remained at a very high level both in the new formats as well as in the classical formats. We found no significant difference in any of the groups. Efficiency improved in all groups when using the sparkline cumulative format and marginally when showing the improved tabular format. When asking medical questions, efficiency and efficacy remained similar between report formats and groups. All alternative reports were subjectively more attractive to the majority of participants. CONCLUSIONS: Showing cumulative reports as a graphical display led to faster detection of general information on the report with the same level of correctness. Considering the familiarity bias of the classical single report formats, the borderline-significant improvement of the alternative tabular format and the non-inferiority of the z-log format, suggests that single reports might benefit from some improvements derived from basic information design.


Asunto(s)
Química Clínica , Satisfacción Personal , Humanos , Laboratorios , Informe de Investigación
5.
Proc Assoc Inf Sci Technol ; 59(1): 121-131, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-36714435

RESUMEN

This study utilized a two-phase user experiment to explore people's perceptual and cognitive states interacting with the COVID-19 dashboard to obtain outbreak information. Specifically, 27 participants were assigned to interact with this dashboard with different color arrangements and performed image-memory, search, and browse visualization tasks sequentially. We found that the participants expected to obtain both global pandemic trends and single region/date statuses from the dashboard to help them grasp important information in the shortest possible time. They also allocated their attention differently to the dashboard's content areas to match their individual visual movement and reading logics. Our participants indicated that the pandemic data visualization dashboard should use a principal-color selection that is alarming but without causing panic. In the study's second phase, an eye-tracking experiment, it was found that the participants' actual eye paths deviated from our expectations: clustering around headings and text, rather than on visualized charts or graphs as anticipated. Based on these findings, we provide design implications for builders of future data-visualization and disaster dashboards.

6.
J Med Libr Assoc ; 109(3): 422-431, 2021 Jul 01.
Artículo en Inglés | MEDLINE | ID: mdl-34629971

RESUMEN

OBJECTIVE: The COVID-19 pandemic highlights the public's need for quality health information that is understandable. This study aimed to identify (1) the extent to which COVID-19 messaging by state public health departments is understandable, actionable, and clear; (2) whether materials produced by public health departments are easily readable; (3) relationships between material type and understandability, actionability, clarity, and reading grade level; and (4) potential strategies to improve public health messaging around COVID-19. METHODS: Based on US Centers for Disease Control and Prevention statistics from June 30, 2020, we identified the ten states with the most COVID-19 cases and selected forty-two materials (i.e., webpages, infographics, and videos) related to COVID-19 prevention according to predefined eligibility criteria. We applied three validated health literacy tools (i.e., Patient Education Materials Assessment Tool, CDC Clear Communication Index, and Flesch-Kincaid Grade Level) to assess material understandability, actionability, clarity, and readability. We also analyzed correlations between scores on the three health literacy tools and material types. RESULTS: Overall, COVID-19 materials had high understandability and actionability but could be improved in terms of clarity and readability. Material type was significantly correlated with understandability, actionability, and clarity. Infographics and videos received higher scores on all tools. CONCLUSIONS: Based on our findings, we recommend public health entities apply a combination of these tools when developing health information materials to improve their understandability, actionability, and clarity. We also recommend using infographics and videos when possible, taking a human-centered approach to information design, and providing multiple modes and platforms for information delivery.


Asunto(s)
COVID-19 , Educación en Salud/métodos , Alfabetización en Salud , Promoción de la Salud/métodos , Difusión de la Información/métodos , Salud Pública/educación , Humanos , Pandemias , SARS-CoV-2 , Gobierno Estatal , Estados Unidos
7.
Health Econ ; 30(6): 1347-1360, 2021 06.
Artículo en Inglés | MEDLINE | ID: mdl-33763902

RESUMEN

This note studies the effect of the availability of a test for a virus on the public health of a population. It is shown by example that the existence of a freely available and moderately informative test for a virus may lower society's welfare in comparison to the case where no test exists or access to the test is restricted. In this setting, any test provided to any subset of agents who would find it optimal not to isolate absent the test improves welfare.


Asunto(s)
Enfermedades Asintomáticas/economía , Prueba de COVID-19/economía , COVID-19/diagnóstico , Modelos Económicos , Neumonía Viral/diagnóstico , COVID-19/epidemiología , Humanos , Neumonía Viral/epidemiología , SARS-CoV-2
8.
Crit Rev Clin Lab Sci ; 58(5): 329-353, 2021 08.
Artículo en Inglés | MEDLINE | ID: mdl-33538219

RESUMEN

In laboratory medicine, much effort has been put into analytical quality in the past decades, making this medical profession one of the most standardized with the lowest rates of error. However, even the best analytical quality cannot compensate for errors or low quality in the pre or postanalytical phase of the total testing process. Guidelines for data reporting focus solely on defined data elements, which have to be provided alongside the analytical test results. No guidelines on how to format laboratory reports exist. The habit of reporting as much diagnostic data as possible, including supplemental information, may lead to an information overload. Considering the multiple tasks physicians have to do simultaneously, unfiltered data presentation may contribute to patient risk, as important information may be overlooked, or juxtaposition errors may occur. As laboratories should aim to answer clinical questions, rather than providing sole analytical results, optimizing formatting options may help improve the effectiveness and efficiency of medical decision-making. In this narrative review, we focus on the underappreciated topic of laboratory result reporting. We present published literature, focusing on the impact of laboratory result report formatting on medical decisions as well as approaches, potential benefits, and limitations for alternative report formats. We discuss influencing variables such as, for example, the type of patient (e.g. acute versus chronic), the medical specialty of the recipient of the report, the display of reference intervals, the medium or platform on which the laboratory report is presented (printed paper, within electronic health record systems, on handheld devices, etc.), the context in which the report is viewed in, and difficulties in formatting single versus cumulative reports. Evidence on this topic, especially experimental studies, is scarce. When considering the medical impact, it is of utmost importance that laboratories focus not only on the analytical aspects but on the total testing process. The achievement of high analytical quality may be of minor value if essential results get lost in overload or scattering of information by using a non-formatted tabular design. More experimental studies to define guidelines and to standardize effective and efficient reporting are most definitely needed.


Asunto(s)
Química Clínica , Medicina , Humanos , Laboratorios , Informe de Investigación
9.
Curr Rev Musculoskelet Med ; 14(1): 9-15, 2021 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-33403625

RESUMEN

PURPOSE OF REVIEW: This narrative review will focus on concepts and methods of Information Design and User Experience for patient education in orthopedics, with osteoarthritis as an application example. RECENT FINDINGS: Information design can make complex health information clear according to the needs of the patients. Digital health presents new opportunities to design scalable educational interventions and may be improved with User Experience Design. Human-centered design methods such as user research, co-design, and prototype testing are being applied in orthopedics to achieve patient-centered care. Current international guidelines on osteoarthritis put patient education as one of the key care strategies. Educational interventions target preoperative education and osteoarthritis self-management, but current models could be enhanced. Patient education and health literacy are fundamental to face the burden of musculoskeletal pain. The collaboration between design and health is essential to deal with the demand for education, behavioral, and social change.

10.
J Theor Biol ; 509: 110513, 2021 01 21.
Artículo en Inglés | MEDLINE | ID: mdl-33075365

RESUMEN

Infamously, the presence of honest communication in a signaling environment may be difficult to reconcile with small (relative) signaling costs or a low degree of common interest between sender (beneficiary) and receiver (donor). This paper posits that one mechanism through which such communication can arise is through inattention on the part of the receiver, which allows for honest communication in settings where-should the receiver be fully attentive-honest communication would be impossible. We explore this idea through the Sir Philip Sidney game in detail and show that some degree of inattention is always weakly better for the receiver and may be strictly better. We compare limited attention to Lachmann and Bergstrom's (1998) notion of a signaling medium and show that the receiver-optimal degree of inattention is equivalent to the receiver-optimal choice of medium.


Asunto(s)
Comunicación , Transducción de Señal , Costos y Análisis de Costo , Teoría del Juego
11.
HERD ; 14(1): 19-30, 2021 01.
Artículo en Inglés | MEDLINE | ID: mdl-32969270

RESUMEN

OBJECTIVE: The purpose of this methodology is to provide the designers of wayfinding systems in healthcare facilities a process for evaluating and optimizing a design prior to implementation. The use of this methodology can improve patient experience in hospitals by preventing the installation of confusing, incomplete, and/or frustrating wayfinding systems. BACKGROUND: Despite known wayfinding and information design principles, wayfinding continues to be a challenge in healthcare environments. One reason is that the design of wayfinding systems is rarely evaluated with end users prior to implementation. The methodology outlined in this article is an application of usability testing that involves end users navigating a space using prototyped signage and other elements of a wayfinding system to determine the effectiveness of the system and identify improvement opportunities. This methodology was developed for use in an emergency department that had outdated signage and required a new wayfinding system. CONCLUSION: This methodology provides a structured process for testing and improving the design of a hospital wayfinding system prior to implementation.


Asunto(s)
Instituciones de Salud , Hospitales , Atención a la Salud , Servicio de Urgencia en Hospital , Humanos
12.
Appl Ergon ; 85: 103079, 2020 May.
Artículo en Inglés | MEDLINE | ID: mdl-32174367

RESUMEN

From an ergonomics perspective, the environmental characteristics should facilitate user activities. Matching user capabilities to demands of the environment is essential. However, about some users such as those with visual impairments, there is little information available for use in designing products and spaces. There is also a gap in information regarding the commutes and needs of the visually impaired, making it even more difficult to establish how environments should be designed to include this population.This study aimed to identify the information needs of people with visual impairment in terms of: 1) Daily life activities, 2) Wayfinding in the complex built environments, 3) Use of the signals provided by the environment 4) Characteristics of the environment which reduce the usability of a space and may put the user in danger, and 5) Safety perception. Data were obtained through a semi-structured interview to which eighteen adults responded. All had either complete blindness or severe visual impairment. For orientation, the most common references were texture or changes in ground level/surface, along with such ambient elements as noise or smells. Information presented in Braille was reported as little used, due to difficulty in finding such information. Regarding safety, participants reported feeling unsafe; most mentioned crossing the street as a major risk. Using auditory, tactile or even olfactory signals may provide important information while commuting: thus, designing signals which consider and highlight these senses is paramount. Assessing features and location of existing tactile signals is also required, to identify opportunities for improving the safety and independence of people with visual impairment.


Asunto(s)
Actividades Cotidianas/psicología , Entorno Construido/psicología , Ergonomía , Trastornos de la Visión/psicología , Personas con Daño Visual/psicología , Adulto , Anciano , Anciano de 80 o más Años , Planificación Ambiental , Femenino , Humanos , Conducta en la Búsqueda de Información , Masculino , México , Persona de Mediana Edad , Orientación , Seguridad , Adulto Joven
13.
J Risk Res ; 23(9): 1177-1194, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-37009131

RESUMEN

The environmental health risk assessment process informs clean-up activities at hazardous waste sites. Ensuring this process is accessible and transparent to communities is crucial for environmental health literacy initiatives. The goals of this project were to develop plain language and effective visuals that can be used when communicating the risk assessment process and methods used to predict excess cancer risk(s) due to environmental exposures. In this study, a community factsheet entitled, "Understanding Environmental Health Risk Assessment" was developed and a participatory design and formative evaluation approach was implemented with a set of representative users (n = 11). Community members living in the vicinity of two Arizona hazardous waste sites as well as three public health professionals/researchers were asked to evaluate the functionality and accessibility of the factsheet, particularly the graphics and whether the text was written in plain language. Participant responses revealed the following major findings: 1) form follows function, 2) graphic elements should outweigh text, 3) line of sight and layout is critical to information accessibility, 4) color coding dramatically aids the reader, 5) content should be strategically grouped, 6) concepts per figure should be minimized to ensure comprehension, 7) interactive content is preferred over static content, and 8) communication efforts need to interweave new information with the targeted audience's past and current environmental health understandings to aid in their ability to retain new concepts. Based on participant feedback, new and improved layout decisions, infographics and accompanying text were designed and prepared. This research demonstrates the need and importance of participatory design, information design prototyping, formative evaluation, and a cultural model of risk communication.

14.
Stud Health Technol Inform ; 257: 341-345, 2019.
Artículo en Inglés | MEDLINE | ID: mdl-30741220

RESUMEN

The practice of patient-centric empowerment with health information delivered through various channels is widespread and often effective. While empowering patients improves the sharing of power between patients and healthcare professionals, it can also inadvertently disempowers healthcare professionals. This paper proposes an approach to the design of health information with the aim of mutually empowering patients and healthcare professionals. The approach consists of mapping a joint journey, identifying the intersecting information points serving both patients and healthcare professionals, and designing the information in a shareable and mutually empowering fashion.


Asunto(s)
Personal de Salud , Informática Médica , Poder Psicológico , Humanos , Participación del Paciente
15.
J Vis Commun Med ; 41(1): 9-17, 2018 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-29325474

RESUMEN

This practice led research project explored visual representation through illustrations designed to communicate often complex medical information for different users within Auckland City Hospital, New Zealand. Media and tools were manipulated to affect varying degrees of naturalism or abstraction from reality in the creation of illustrations for a variety of real-life clinical projects, and user feedback on illustration preference gathered from both medical professionals and patients. While all users preferred the most realistic representations of medical information from the illustrations presented, patients often favoured illustrations that depicted a greater amount of information than professionals suggested was necessary.


Asunto(s)
Educación Médica/métodos , Ilustración Médica , Humanos , Nueva Zelanda
16.
Accid Anal Prev ; 112: 15-20, 2018 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-29306086

RESUMEN

At crosswalks with countdown timers, pedestrians arriving at the clearance phase tend to start crossing when the remaining time is too short. It is unclear whether this phenomenon is due to errors in judging the possibility to finish crossing before signal lights turning red. This study evaluated and compared pedestrians' accuracy in judgment of crossing possibility based on two cues: the amount of remaining time, and the minimum required speed to finish crossing within clearance phase (road width / remaining time). The results showed that pedestrians overestimated crossing possibility when they made judgments based on remaining time, especially when the road was narrow. By contrast, the display of required speed resulted in higher overall accuracy and lower false alarm rate, due to higher sensitivity to different crossing possibilities and more conservative set of response criterion. This advantage is consistent across different road widths. These findings suggest that pedestrians' risky decisions based on the countdown timers are partly induced by overestimation of crossing possibilities. The advantages of required-speed display over traditional countdown timers indicate a strong possibility to improve pedestrian judgments by information design.


Asunto(s)
Accidentes de Tránsito/prevención & control , Juicio , Peatones/psicología , Toma de Decisiones , Planificación Ambiental , Femenino , Humanos , Masculino , Factores de Tiempo
17.
Res Social Adm Pharm ; 14(2): 196-202, 2018 02.
Artículo en Inglés | MEDLINE | ID: mdl-28285793

RESUMEN

The design of medicine information leaflets can determine whether a leaflet will be read or discarded by patients. It may also influence patients' ability to understand the information about their medicines within the leaflet. Researchers compared regulatory agencies' recommendations for medicine information leaflet design from New Zealand, the United Kingdom, the European Union, and the United States against recommended good design principles to determine the appropriateness, comprehensiveness, and consistency of their recommendations. Recommendations for medicine information leaflets varied between the regulatory agencies. There were some inconsistencies between the recommendations and some gaps were identified. There was little regulatory guidance given to creators of medicine information leaflets in New Zealand compared to other countries, and this could lead to manufacturer-produced information leaflets of a poorer quality. Up-to-date and enforceable guidance for creators of medicine information leaflets should be provided in all countries to ensure they are of an appropriate standard.


Asunto(s)
Etiquetado de Medicamentos/normas , Agencias Gubernamentales , Folletos , Unión Europea , Nueva Zelanda , Reino Unido , Estados Unidos
18.
Stud Health Technol Inform ; 241: 147-152, 2017.
Artículo en Inglés | MEDLINE | ID: mdl-28809198

RESUMEN

Many people around the world use prescription medications. Consumers often require information about their medications to support taking them safely and effectively. One source of such information is Consumer Medication Information (CMI). Canadians typically receive printed CMI when a new prescription is filled whereas Danes have the online resource min.medicin.dk. This study compared the content and design of Danish and Canadian CMI. Danish CMI satisfied seven of the 11 content utility criteria (developed in previous work) identified as supporting the safe and effective medication use. However, Danish CMI provided a more information about how frequently possible side effects occur and multimedia (e.g., images, videos) directions for some medications. This study examined some of the similarities and differences between how Canadians and Danes are informed about medications. However, further research is required to determine what content and methods of delivery are most beneficial in supporting safe and effective medication use.


Asunto(s)
Efectos Colaterales y Reacciones Adversas Relacionados con Medicamentos , Multimedia , Medicamentos bajo Prescripción , Canadá , Dinamarca , Humanos , Educación del Paciente como Asunto
19.
Res Social Adm Pharm ; 13(6): 1186-1190, 2017 11.
Artículo en Inglés | MEDLINE | ID: mdl-27818214

RESUMEN

Medicines information leaflets can equip patients to be in control of their own healthcare and support the safe and effective use of medicines. The design and content of leaflets influences patients' willingness to read them, and poor examples can cause patient confusion and anxiety. Researchers examined the literature over the past 8 years to determine the content and design of medicine information leaflets that patients prefer in order to read, understand, and use them effectively. It was found that existing leaflets do not meet patients' needs and appear ineffective. Leaflets lack the information patients seek and may contain non-essential material, affecting patients' perception of, and willingness to read them. Additionally, the acceptable leaflet length varies between patients. Application of good design principles improves readability, comprehension, and ability to locate information. Medicine information leaflets must meet patients' needs and be well designed. Tailoring information leaflets to patient characteristics and requirements would enhance effectiveness. Passive provision of pre-printed leaflets is outdated, unvalued and ineffective. Using automated computer systems for leaflet tailoring with the ability to further adapt patients' information might be the best way forward.


Asunto(s)
Etiquetado de Medicamentos , Satisfacción del Paciente , Humanos , Folletos
20.
Clin Trials ; 13(4): 391-9, 2016 08.
Artículo en Inglés | MEDLINE | ID: mdl-27136947

RESUMEN

BACKGROUND: Interim monitoring is a key component of randomized clinical trial design from both ethical and efficiency perspectives. In studies with time-to-event endpoints, timing of interim analyses is typically based on observing a pre-specified proportion of the total number of events required for the final analysis. While most randomized clinical trial designs pool events over the experimental and control arms in determining the analysis times, some designs use only the control-arm events for scheduling interim looks. PURPOSE: To evaluate the performance of the pooled and control-arm-based interim monitoring approaches and to propose a new procedure, the earliest information time procedure, that combines the benefits of the two approaches. METHODS: The analytical and logistical considerations for the procedures are presented. The methodology is illustrated on data from three published randomized clinical trials. The procedures are compared in a simulation study. RESULTS: The control-arm approach results in a slight inflation of the study type I error in one-sided randomized clinical trial designs. When the new treatment is no better than the control treatment, the pooled-arm approach results in, on average, earlier stopping times than the control-arm approach. When the new treatment works exceptionally well, the average stopping times under the control-arm approach are earlier than those under the pooled approach. The proposed earliest information time procedure is shown to result in stopping times corresponding to the best (earliest) of the two approaches over the entire range of alternatives. LIMITATIONS: The earliest information time procedure may result in a slight inflation of the type I error (especially in small trials); when exact control of the type I error is required, it is necessary to use a simulation-based method to correct the inflation. CONCLUSION: In time-to-event settings, the earliest information time procedure is an attractive alternative to the pooled and control-arm approaches. Improving the timing of interim analyses helps to minimize patient exposure to inferior treatments and to accelerate dissemination of the study results.


Asunto(s)
Terminación Anticipada de los Ensayos Clínicos , Determinación de Punto Final/normas , Ensayos Clínicos Controlados Aleatorios como Asunto , Proyectos de Investigación , Estudios de Casos y Controles , Interpretación Estadística de Datos , Toma de Decisiones , Humanos , Inutilidad Médica , Ensayos Clínicos Controlados Aleatorios como Asunto/estadística & datos numéricos , Factores de Tiempo , Resultado del Tratamiento
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