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1.
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi ; 38(9): 1098-1104, 2024 Sep 15.
Artículo en Chino | MEDLINE | ID: mdl-39300885

RESUMEN

Objective: To investigate the characteristics of the clinical application of ulnar artery flap in the repair of oral and maxillofacial soft tissue defects. Methods: The clinical data of 12 patients with oral and maxillofacial defects repaired with ulnar artery flap between June 2021 and July 2023 was retrospectively analyzed. Among them, 11 cases were male and 1 case was female; their ages ranged from 28 to 76 years, with a mean age of 54.8 years. The lesions were located in the lateral margin of the tongue in 3 cases, the root of the tongue in 2 cases, the base of the tongue in 4 cases, and the buccal region, upper gingiva, and lower lip in 1 case each. The pathological types were squamous cell carcinoma in 11 cases and adenoid cystic carcinoma in 1 case; according to the TNM staging of the International Union Against Cancer (UICC), there were 5 cases of T 3N 0M 0, 2 cases of T 3N 1M 0, 1 case of T 4aN 0M 0, 1 case of T 4aN 1M 0, 1 case of T 4aN 2bM 0, and 2 cases of T 4aN 2cM 0. After complete resection of the lesion, the defect ranged from 6 cm×3 cm to 8 cm×5 cm. Preoperatively, colour Doppler ultrasound was used to detect the non-dominant forearm, measure the thickness of the subcutaneous fat in the donor area, confirm and mark the ulnar artery and reflux vein, and measure the diameter of the vessels, flow velocity, and the perforator position; intraoperatively, the flap was designed, prepared, anastomosed, and positioned according to the corresponding data. The vessels were all anastommosed with one artery and two veins to form a super-reflux. After complete hemostasis, the defects were repaired with sliding flap (2 cases), direct suture (4 cases), biomembrane (2 cases), or razor thin skin graft (4 cases). Results: No vascular crisis occurred after operation, and all the flaps survived in 12 cases. Wounds in the donor site healed by first intention in 10 cases and by second intention in 2 cases. Wounds in the recipient site healed by first intention in all cases. All 12 patients were followed up 5-18 months, with an average of 11.4 months. The colour and texture of the flap were normal. The function of hand and upper limb was evaluated according to the trial standard of upper limb function assessment of the Chinese Society of Hand Surgery of the Chinese Medical Association, and the score was 65-81 (mean, 71.3), and achieved excellent in 1 case and good in 11 cases. The score of Oral Health Impact Scale (OHIP) was 9-18, with an average of 14.2, and the oral function was satisfactory. During the follow-up, 1 case had local recurrence and underwent extended resection again, while the other patients had no recurrence or metastasis. Conclusion: For moderate soft tissue defects with complex oral and maxillofacial function, ulnar artery flap repair is effective.


Asunto(s)
Procedimientos de Cirugía Plástica , Colgajos Quirúrgicos , Arteria Cubital , Humanos , Masculino , Persona de Mediana Edad , Femenino , Adulto , Arteria Cubital/cirugía , Anciano , Procedimientos de Cirugía Plástica/métodos , Colgajos Quirúrgicos/irrigación sanguínea , Traumatismos de los Tejidos Blandos/cirugía , Carcinoma de Células Escamosas/cirugía , Trasplante de Piel/métodos
2.
J Stomatol Oral Maxillofac Surg ; : 102032, 2024 Sep 02.
Artículo en Inglés | MEDLINE | ID: mdl-39233053

RESUMEN

BACKGROUND: The imaging manifestations of oral and maxillofacial myofibroma/myofibromatosis can vary among patients. Although many clinical cases have been reported, a consensus on the clinicopathological features of and treatment principles for this disease is lacking. PURPOSE: This study aimed to summarize the clinicopathological features of solitary myofibroma of the oral and maxillofacial regions in pediatric patients. METHODS: The clinical data, histological features, and immunohistochemical characteristics of ten pediatric patients who underwent surgical removal and subsequent pathological diagnosis of myofibroma were collected and retrospectively and cross-sectionally analyzed. RESULTS: Seven patients were male, and 3 were female, with ages ranging from 3 months to 6 years (mean: 2.6 years). The patients presented with solitary lesions involving the mandibular gingiva and adjacent mandible (4 patients), mandible (2 patients), oral floor and submandibular area and adjacent mandible (1 patient), gingiva (1 patient), maxilla (1 patient), and oropharynx (1 patient). Light microscopy revealed spindle-shaped tumor cells organized in bundles or vortex patterns, forming a hemangiopericytoma-like perivascular pattern, whereas immunohistochemical staining revealed diffuse smooth muscle actin (SMA) positivity. All patients underwent surgical resection, and none experienced recurrence over the 12- to 82-month follow-up. CONCLUSIONS: Solitary myofibroma in the oral and maxillofacial regions is predominantly observed in infants and young children, with a higher incidence among males. The prognosis is favorable following localized lesion resection or curettage of jawbone lesions. Accurate recognition of the clinical, radiological, and pathological features of the disease will reduce the misdiagnosis rate.

3.
Hua Xi Kou Qiang Yi Xue Za Zhi ; 42(5): 671-674, 2024 Oct 01.
Artículo en Inglés, Chino | MEDLINE | ID: mdl-39304512

RESUMEN

Rosai-Dorfman disease (RDD) is a rare non-Langerhans cell histiocytosis. The etiology and pathogenesis of RDD have not been fully explained, and its occurrence is even rarer in the maxillofacial region. This paper reported a patient who was first misdiagnosed as facial inflammation caused by oral disease and finally diagnosed as RDD. Clinical features, diagnosis, treatment, and prognosis were discussed based on the literature. This work provides reference for future diagnosis and differentiation of RDD in cheek.


Asunto(s)
Errores Diagnósticos , Histiocitosis Sinusal , Inflamación , Humanos , Histiocitosis Sinusal/diagnóstico , Inflamación/diagnóstico , Cara
4.
J Pharm Bioallied Sci ; 16(Suppl 3): S2779-S2781, 2024 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-39346134

RESUMEN

Background: One potential long-term side effect of surgery in the oral and maxillofacial region is neurosensory impairment. Due to their physical proximity to the surgical location, the lingual nerve (LN) and inferior alveolar nerve (IAN), two sensory segments of the trigeminal nerve, are always susceptible to damage during third molar extraction. Aim: Assessment of the impact of different surgical techniques on nerve function and sensation after maxillofacial surgery. Methods and Materials: There was retrieval of information from medical records of study participants regarding the presence of symptoms like paresthesia, numbness, loss of sensation in lower lip, difficulty in movement of tongue, and all other findings observed after 7 days of surgical procedures. Clinically neurosensory examinations were utilized to assess nerve damage. Pinprick testing and the two-point discrimination test were used. Results: Seven male patients were found to have damage to LN while nine males suffered damage to trigeminal nerve. 12 female patients were found to have damage to LN while 16 females suffered damage to trigeminal nerve. In total 19 patients suffered damage to LN while 25 patients suffered damage to trigeminal nerve. Conclusion: The incidence of LN damage was 9.5%, and the incidence of trigeminal nerve damage was 12.5%.

5.
Med J Armed Forces India ; 80(4): 387-391, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-39071763

RESUMEN

Reconstructing maxillofacial defects is quiet challenging due to the region's complex anatomy, and cosmetic and functional effects on patients. With the help of developing technologies, patient-specific implants (PSIs) using virtual surgical planning based on a Computer aided designing (CAD)/Computer aided manufacturing (CAM) platform is an evolving treatment option. PSIs can be used in patients with maxillofacial defects and reconstruction. PSIs are also being used in the form of preformed plates for virtually planned orthognathic surgeries. Customized temporomandibular joint (TMJ) prosthesis is being routinely used in the debilitating/degenerative joint disease as a part of alloplastic joint replacement. The reconstruction of the maxillofacial region using autogenous tissue will always be gold standard due to near match of the recipient site. However, autogenous bone grafts positioned using PSIs or in certain areas such as the TMJ complex and the orbital region the PSIs are being offered with advantage of reduced donor-site morbidity. The future research is focussed towards the development of PSIs being used as a scaffold for engineering of the recipient tissue to restore the lost anatomy of specific region. This article reviews the varied aspects of this new technology of PSI for correction of various deformities/defects during the maxillofacial reconstruction.

6.
Int Wound J ; 21(6): e14915, 2024 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-38888249

RESUMEN

Necrotizing fasciitis (NF) is a rare, dangerous, potentially fatal infectious disease of soft tissue. The treatment consists of antibiotic therapy, surgical debridement and subsequent reconstruction. Hyperbaric oxygen (HBO) therapy has been applied in NF patients recently, so our aim was to gather the findings and outcomes for HBO therapy. A PubMed and Google Scholar literature search was conducted regarding the effect of HBO therapy in patients with NF following key words: 'necrotizing fasciitis' AND 'maxillofacial region' OR 'head and neck' AND 'hyperbaric oxygen' OR 'HBO'. A total of 3333 studies have been identified, of which only 16 articles met the inclusion criteria of this review. A conclusion was made, that aggressive combinations of antibiotics and surgical debridement followed by incorporation of HBO therapy, as an adjuvant treatment, in patients with NF and in company by immunoglobulin therapy are showing promising results. In addition, multi-centric studies should be in consideration for further research.


Asunto(s)
Fascitis Necrotizante , Oxigenoterapia Hiperbárica , Humanos , Antibacterianos/uso terapéutico , Desbridamiento/métodos , Fascitis Necrotizante/terapia , Oxigenoterapia Hiperbárica/métodos , Resultado del Tratamiento
7.
J Oral Maxillofac Pathol ; 27(3): 597-598, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-38033945

RESUMEN

Background: One of the most challenging spectra of lesions in the oral and maxillofacial region (OMFR) are round-cell tumours (RCTs). They show a considerable degree of overlap in microscopy and immunophenotypes. The main aim of this study is to analyse the spectrum of RCTs encountered in the oral and maxillofacial regions. We emphasise the role of immunohistochemistry (IHC) which in conjunction with histological, clinical, and imaging findings is necessary for their correct characterisation. The secondary objectives are to discuss differential diagnosis, workflow, and diagnostic algorithm for round-cell lesions affecting the OMFR. Methods: Formalin-fixed, paraffin-embedded sections of RCTs were retrieved from the archives of the Department of Oral Pathology (January 2018 to March 2020). These cases were analysed by three pathologists independently by evaluating haematoxylin and eosin-stained sections, and immunohistochemical markers employed to characterise these lesions. Results: Under the spectrum of RCTs, 11 cases (0.53%) were diagnosed with a predominance of non-Hodgkin lymphoma (55%) followed by Ewing sarcoma (18%). The remaining were Langerhans cell histiocytosis (9%), neuroendocrine carcinoma (9%), and sinonasal undifferentiated carcinoma (9%). Except for one case, in all cases, the final diagnosis was established with the use of adjunctive IHC. Conclusion: RCTs can pose a diagnostic challenge for inexperienced oral pathologists. Thorough knowledge of the differentials of RCT occurring in oral and maxillofacial is helpful. An algorithm-based diagnostic approach incorporating the clinical, imaging, and histomorphological findings and immunohistochemical evaluation can help in minimizing diagnostic confusion and errors.

8.
Cureus ; 15(9): e46025, 2023 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-37766776

RESUMEN

Background In this study, we aimed to determine the prevalence and radiographic features of incidental head and neck soft tissue calcifications (STCs) on panoramic imagesand assess their clinical significance. Methodology Following well-established training and calibration procedures, 9,553 digital panoramic radiographs (DPRs) taken between January 1, 2021, and January 31, 22, were retrospectively evaluated. Only obvious calcifications and clear differential diagnoses were considered. The presence, type, side (i.e., unilateral or bilateral), number (single or multiple), and the presence of different calcifications in the same individual were recorded. STCs were recorded according to age and gender. Data were analyzed using the chi-square test and Fisher's exact test using SPSS version 18.0 (IBM Corp., Armonk, NY, USA). Results Overall, 35.8% of the DPRs studied showed the presence of STCs, including ossified stylohyoid complex (OSHC) (10.3%), thyroid cartilage (9.8%), tonsillolith (9.2%), atherosclerotic plaques (5.8%), calcified triticeous cartilage (CTC) (5.1%), sialolith (1.9%), as well as intra-articular (1.3%) and other calcifications (0.1-0.8%), i.e., calcified lymph node, antrolith, rhinolith, phlebolith, and osteoma cutis. STCs were found to be more prevalent in middle-aged patients and in females. A significant relationship was identified between the presence of carotid artery calcification and calcified superior horn of thyroid cartilage (CSHTC), as well as between the presence of CSHTC and CTC. Calcifications were detected either bilaterally (n = 2,003) or unilaterally (n = 2,388); however, OSHC mostly showed bilateral calcifications (8.5%). Conclusions Panoramic radiographs of dental patients reveal the frequent occurrence of STCs in the head and neck region with differing radiographic features. Certain calcifications show gender and age differences. Accurate detection of STCs may guide the identification of potential underlying diseases and help initiate referral to the relevant multidisciplinary teams.

9.
J Orthod Sci ; 12: 35, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-37351396

RESUMEN

BACKGROUND AND PURPOSE: The soft-tissue layer and facial skeleton influence the harmony and equilibrium of the face. The evaluation of the patient's structural and soft-tissue features is one of the most crucial steps in preparing for the diagnosis and treatment of oral-maxillofacial orthodontics. Clinicians can intervene with the proper treatment at the proper time to achieve the best results by being aware of the traits and variations of soft tissue at various developmental stages and in various races. To obtain a consistent treatment result in terms of function and aesthetically pleasing results, patients, and forecast, the growth that may take place after the orthopedic therapy has concluded. OBJECTIVE: To examine the soft-tissue features of the oral-maxillofacial area in Vietnamese adults (aged 18-25 years) by evaluating cephalometric radiographs. MATERIALS AND METHODS: In a cross-sectional descriptive study, 85 students from Can Tho University of Medicine and Pharmacy took part. Students' lateral cephalograms were taken in compliance with the sample requirements. RESULTS: Men's lip protrusion (4.30 ± 0.71) was higher than women's (3.88 ± 0.97) (P = 0.024 <.05) and men's (-4.88 ± 0.93) chin lip groove depth was higher than women's (-4.24 ± 0.93) (P = 0.002), both with a P value of. 05. CONCLUSIONS: The study identified a statistically significant difference in the protrusion of the top lip and the depth of the cleft lip between the male and female, demonstrating that the soft-tissue features of Vietnamese students were distinct from those of other races.

10.
Cureus ; 15(5): e38999, 2023 May.
Artículo en Inglés | MEDLINE | ID: mdl-37323316

RESUMEN

Representing unusual fracture patterns is extremely important to understand. A 27-year-old male patient with a known history of a road traffic accident with sustained injury reported to the Department of Oral and Maxillofacial Surgery in Saveetha Dental College with pain in the left and right lower jaw region of three days duration. The patient provided a history of frontal impact in the symphysis region after a fall from a two-wheel vehicle. Clinical examination revealed a laceration of 2 cm in the chin region with bilateral pre-auricular swelling and trismus with an anterior open bite. The computed tomography scan revealed a bilateral dicapitular condyle fracture with an oblique impacted fracture of the symphysis with a displaced inferior border and left lingual cortical displacement. Apart from this, an incomplete fracture was evidenced, extending along the inferior border to the right body of the mandible. The fracture site was exposed through the laceration. The impacted mandibular fracture segments were mobilized and fixation was done using a 2 mm five-hole plate at the lower border across the sagittally split segment after placement of maxillomandibular fixation with an arch bar at the alveolar border as a part of tension banding. The oblique lingual fracture was reduced and fixed with a 2 x 14 mm bicortical screw. The primary objective of the current case report is to elucidate an unusual fracture of the mandible and discuss the management of such impacted mandibular fractures.

11.
Stomatologiia (Mosk) ; 102(2): 46-53, 2023.
Artículo en Ruso | MEDLINE | ID: mdl-37144768

RESUMEN

Primordial odontogenic tumor (POT) is a rare benign mixed epithelial and mesenchymal odontogenic tumor that has been included as a new nosological form in the latest classification of the World Health Organization (WHO 2017). The first two clinical cases of POT treatment in children in Russia are presented. A comprehensive examination and surgical treatment of POT were carried out. The diagnosis was confirmed morphologically. OBJECTIVE: To inform maxillofacial surgeons and dentists about the clinical, radiological and morphological features of POT on the example of clinical experience and literature data.


Asunto(s)
Tumores Odontogénicos , Humanos , Niño , Tumores Odontogénicos/diagnóstico por imagen , Tumores Odontogénicos/cirugía , Federación de Rusia
12.
Cureus ; 15(2): e35487, 2023 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-37007388

RESUMEN

Objective The purpose of the study was to assess the clinical outcome of patients by using n-butyl-2-cyanoacrylate in the management of comminuted fracture segments of the anterior wall of the maxillary sinus in the zygomatico-maxillo-facial complex region. Material and methods A prospective study was done at a tertiary care teaching institute in India with a study population of ten patients in a single group. The method of recruitment was a convenient sampling method. Out of all the study subjects, three patients had isolated maxillary sinus wall fractures, whereas the remaining seven had other associated facial fractures that required stable fixation with mini plates. The comminuted fractures of the anterior wall of the maxillary sinus were carefully reduced through an intra-oral approach, and n-butyl-2-cyanoacrylate was applied over the edges of fractured segments. The segments were left undisturbed for one minute and closed with a 3-0 vicryl. The outcome variables, namely bone alignment visualised through computed tomography (CT) scan postoperatively, paresthesia or hypoesthesia of the infraorbital nerve, postoperative infection, and wound dehiscence, were noted at one-week, one-month, three-month, and six-month intervals. Data were analysed using the Chi-square test. Results Among all patients, seven had satisfactory bone alignment. A total of seven patients recovered from hypoesthesia of the infraorbital nerve. The association of bone alignment with hypoesthesia or paresthesia revealed a highly significant p-value (0.002) using the Chi-square test. Also, an association between postoperative infection and wound dehiscence showed substantial results with a p-value less than 0.05. Conclusion Good bone alignment was seen postoperatively in 70% of patients. The cyanoacrylate used had no adverse reactions, and its application was restricted to non-load-bearing areas in this study. Further studies with a higher level of evidence and a larger sample size are needed to validate the use of adhesives for bone fixation in other regions of the face.

13.
Cancer Med ; 12(3): 2368-2377, 2023 02.
Artículo en Inglés | MEDLINE | ID: mdl-35933718

RESUMEN

BACKGROUND: No study has evaluated the impact of regimen on recurrence, metastasis and survival in patients with adenoid cystic carcinoma (ACC). The present study aimed to compare the efficacy of radioactive seed implantation and other regimens in treating ACC, so as to investigate the clinical applicability of radioactive seed implantation and determine the indications for this regimen. METHODS: A total of 188 patients with ACC in oromaxillofacial region were allocated to four groups according to the treatment regimen: group 1 was treated with a combination of surgery and 125 I seed therapy, group 2 with a combination of surgery and external radiotherapy, group 3 with surgery, whereas group 4 was untreated. The Kaplan-Meier method was used to assess the survival rates, and the Cox regression analyses were used to identify the associated prognostic factors. RESULTS: The overall survival rates of 188 patients and groups 1, 2, 3 and 4 were 85.7%, 75%, 68.2% and 37.5%, respectively. Cox regression analysis revealed that age, T stage, N stage and regimen were independent prognostic factors of survival. Amongst patients with primary ACC, the efficacy of radioactive seed implantation was higher in those with perineural invasion than in those without. CONCLUSION: Patient age, T stage, N stage and regimen are independent prognostic factors of survival in patients with ACC. Patients treated with surgery combined with postoperative 125 I seed radiotherapy have a higher overall survival rate, and those with perineural invasion are more suitable for radioactive seed implantation therapy.


Asunto(s)
Braquiterapia , Carcinoma Adenoide Quístico , Humanos , Carcinoma Adenoide Quístico/patología , Pronóstico , Análisis de Regresión , Terapia Combinada , Tasa de Supervivencia , Recurrencia Local de Neoplasia/patología , Estudios Retrospectivos
14.
Cureus ; 15(12): e49772, 2023 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-38164313

RESUMEN

Myxomas, characterized by abundant mucoid stroma and spindle cells, represent a subset of benign soft tissue tumors. Intramuscular myxomas in the maxillofacial region are rare, posing diagnostic challenges. We present the case of a 58-year-old male who reported limited jaw movement. Physical examination revealed asymmetry, restricted mouth opening, and left lateral jaw movement. Imaging confirmed a well-defined myxomatous mass. Core needle biopsy confirmed an intramuscular myxoma involving the pterygoid and masseteric muscles. A multidisciplinary team opted for surveillance due to its benign nature. Follow-up at six months showed stable findings, supporting the decision for non-surgical management. This case highlights the diagnostic and management challenges of rare intramuscular myxomas in the maxillofacial region. A comprehensive diagnostic work-up, including clinical, radiological, and histopathological data, is crucial. Non-surgical management, guided by a benign nature, underscores the importance of judicious and multidisciplinary approaches. Regular follow-up contributes to understanding the natural history of intramuscular myxomas, emphasizing the need for vigilant monitoring in soft tissue tumor management.

15.
J Clin Med ; 11(19)2022 Sep 26.
Artículo en Inglés | MEDLINE | ID: mdl-36233557

RESUMEN

Symmetry is representative of aesthetics and health in all kinds of vertebrates, especially the human face. Therefore, to automatically locate the appropriate symmetry plane is crucial. The aim of this study was to develop an automatic and reliable method to determine the symmetry plane of the maxillofacial region. We compared the proposed method of determining the symmetry plane by assessing landmark-based and surface-based methods by way of quantitative symmetry assessments. Statistical analysis was applied to evaluate whether significant difference existed among these three kinds of symmetry planes. Twenty cases who had a diagnosis of severe facial asymmetry were evaluated retrospectively. The results showed that searching for the symmetry plane using a voxel-based method, named the optimal symmetry plane (OSP), achieved the most representative symmetry according to the outcomes of the trials. The OSP was significantly more symmetrical than the other two planes, as determined by other methods. The paired-voxel computation method proposed in this research is a robust and reliable method for identifying the unique symmetry plane for patients with severe facial asymmetry. Symmetry is of crucial significance for all kinds of vertebrates, including its clinical implications for surgical planning in orthognathic surgery.

16.
Saudi Dent J ; 34(6): 445-448, 2022 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-36092523

RESUMEN

Purpose: The article subject relevance is conditioned by poor knowledge of the aetiology and pathogenesis of inflammatory diseases in this area. The purpose of this study was to identify the most rational approach to solving the issues of improving methods for treating arthritis and arthrosis. Methods: The leading approach was the combination of the analysis results concerning the clinical examination of dental patients of various age groups with the logical construction of conclusions drawn from the research results. The paper presented the clinical examination data of patients with TMJ pathologies of various age groups and described the methods of their treatment. Results: The results include the main effective methods identification for the diagnostics and treatment of inflammatory diseases in the temporomandibular joint and the main prospects for improving these methods in the future, with the aim of a general expansion of ideas regarding the possibilities of diagnostics and treatment of such diseases. Conclusion: The study value lies in the possibility of using its results in practical dentistry to bring practical improvements to the currently available methods for diagnostics and treatment of inflammatory TMJ diseases.

17.
Stomatologiia (Mosk) ; 101(4): 30-33, 2022.
Artículo en Ruso | MEDLINE | ID: mdl-35943497

RESUMEN

The article presents the development of functional research methods in the maxillofacial region, methods of their application and the results of scientific research on the study of the neuromuscular balance of the masticatory muscles with defects and deformations in the maxillofacial region. Methods of blood circulation research (laser doppler flowmetry, ultrasound dopplerography, computer capillaroscopy) have been developed and implemented in the tissues of the maxillofacial region: periodontal, tooth pulp, in the mucous membrane of the alveolar ridge, which allowed us to study the mechanisms of disease pathogenesis and monitor the effectiveness of treatment in the maxillofacial region.


Asunto(s)
Proceso Alveolar , Pulpa Dental , Odontología , Humanos , Flujometría por Láser-Doppler , Microcirculación/fisiología
18.
West Afr J Med ; 39(6): 628-634, 2022 Jun 24.
Artículo en Inglés | MEDLINE | ID: mdl-35752969

RESUMEN

BACKGROUND: Neurogenic tumors constitute a group of true and pseudo-tumors arising from tissues derived from embryonic neural crest cells. They are rare in the maxillofacial region. OBJECTIVES: To analyze the demographic, clinical presentation and histopathological spectrum of neurogenic tumors of the oral and maxillofacial region seen over a 28-year period. MATERIAL AND METHODS: A retrospective observational study which highlighted the demographic, clinical presentation and histopathological spectrum of neurogenic tumors of the oral and maxillofacial region seen between 1992 and 2020 in a tertiary health facility. RESULTS: A total of 56 patients were studied with a male to female ratio of 1:1.5 and the age spanned from 1 to 72 years (mean of 26.2 ± 17.9 yrs). The commonly involved sites were the cheek (n = 9; 16.0%), scalp (n = 9; 16.0%) and eyelid (n = 6; 10.7%). Histopathological data showed a preponderance (n = 38; 67.9%) of neurofibroma over other types of neurogenic tumors. The treatment modalities used were surgical (n = 37; 94.9%) and oncological (n = 2; 5.1%). Complications noted were recurrence in 2 patients and hypertrophic scar formation in 1 patient. CONCLUSION: In this environment, orofacial neurogenic tumors appear to be common in the second decade of life, affect the extraoral structures mainly and the most common form is neurofibroma.


CONTEXTE: Les tumeurs neurogènes constituent un groupe de tumeurs vraies et pseudo-tumorales provenant des tissus dérivés des cellules de la crête neurale embryonnaire. Elles sont rares dans la région maxillo-faciale. OBJECTIFS: Analyser la démographie, la présentation clinique et le spectre histopathologique des tumeurs neurogènes de la région orale et maxillo-faciale observées sur une période de 28 ans. MATÉRIEL ET MÉTHODES: Une étude d'observation rétrospective qui a mis en évidence la démographie, la présentation clinique et le spectre histopathologique des tumeurs neurogènes de la région orale et maxillo-faciale observées entre 1992 et 2020 dans un établissement de santé tertiaire. RÉSULTATS: 56 patients au total ont été étudiés, avec un rapport hommes/femmes de 1:1,5 et un âge compris entre 1 et 72 ans (moyenne de 26,2 ± 17,9 ans). Les sites les plus fréquemment touchés étaient la joue (n=9; 16,0%), le cuir chevelu (n=9 ; 16,0%) et la paupière (n=6 ; 10,7%). Les données histopathologiques ont montré une prépondérance (n=38 ; 67,9%) de neurofibromes par rapport aux autres types de tumeurs neurogènes. Les modalités de traitement utilisées étaient chirurgicales (n=37; 94,9%) et oncologiques (n=2; 5,1%). Les complications notées ont été la récidive chez 2 patients et la formation d'une cicatrice hypertrophique chez 1 patient. CONCLUSION: Dans cet environnement, les tumeurs neurogènes orofaciales semblent être fréquentes dans la deuxième décennie de vie, affectent principalement les structures extraorales et la forme la plus fréquente est le neurofibrome. Mots clés: Tumeur du système nerveux, Neurofibrome, Visage, région orale et maxillo-faciale.


Asunto(s)
Neoplasias de la Boca , Neurofibroma , Adolescente , Adulto , Anciano , Niño , Preescolar , Femenino , Humanos , Lactante , Masculino , Persona de Mediana Edad , Neoplasias de la Boca/epidemiología , Neoplasias de la Boca/patología , Neurofibroma/patología , Neurofibroma/cirugía , Nigeria/epidemiología , Estudios Retrospectivos , Adulto Joven
19.
Stomatologiia (Mosk) ; 101(3): 31-37, 2022.
Artículo en Ruso | MEDLINE | ID: mdl-35640177

RESUMEN

THE AIM OF THE STUDY: To study the frequency and structure of the incidence of facial furuncle in military personnel of St. Petersburg and Leningrad region and civilians. To conduct a comparative analysis of the nature of the course, duration and outcome of the disease in military personnel and civilians (according to case histories). MATERIAL AND METHODS: From 5744 case histories of patients with purulent-inflammatory processes of the maxillofacial region treated at the clinic of the Department of ChLH and Surgical Dentistry of the Kirov Medical University and St. Petersburg State Medical Institution «City Hospital No. 15¼ from 2017 to 2019, 201 case histories of patients with facial furuncle were isolated and analyzed. RESULTS: According to the results of a study conducted from 2017 to 2019 in the clinic of the Department of CHLH and surgical Dentistry, a facial furuncle was detected in 65 cases. In the general structure of purulent-inflammatory diseases of the maxillofacial region, it was 3.1%. In the department of ChLH GB No. 15, 136 people were treated, which amounted to 3.7%. A lower percentage of the disease in military personnel is associated with early detection and timely initiation of treatment of purulent-inflammatory diseases of the skin. Weekly inspections of military personnel in military units, allow to avoid the development of complicated forms of their course. 95.0% of military personnel (47.0% of them contractors) and 51.0% of civilians were in the age group from 17 to 21 years. The main cause of the disease - hypothermia - in military personnel was 32.1%, in civilians - 20.9%. More often, the furuncle disease occurred in the spring: in military personnel in 44.6%, in civilians in 30.7% of cases. Localization of a boil in the buccal region occurred in military personnel in 15.4% of cases, and in civilians - in 20.8% of cases. CONCLUSION: To prevent the disease of facial frunculus in military personnel, it is necessary to improve methods of prevention, diagnosis and treatment of patients, to provide consultations of related specialists: dermatovenerologist, endocrinologist, immunologist. In addition, it is necessary to observe the rules of personal hygiene with the use of individual skin care products (according to the type of facial skin), hardening of the body and vitamin therapy.


Asunto(s)
Forunculosis , Personal Militar , Adolescente , Adulto , Animales , Humanos , Incidencia , Adulto Joven
20.
Front Med (Lausanne) ; 9: 852678, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-35391888

RESUMEN

Fibrodysplasia ossificans progressiva (FOP) is a rare genetic disorder characterized by heterotopic ossification (HO) of the skeletal muscles, fascia, tendons and ligaments. Patients often experience limitations in jaw function due to HO formation in the maxillofacial region. However, no studies have yet analyzed the age of onset and location of HO and the type of restrictions it may yield in the maxillofacial region. The aim of this study was to evaluate all existing literature on the site of onset of HO and associated functional restrictions of the jaw. To this end, a scoping review was performed focusing on limitations of jaw movement in FOP patients. The literature search resulted in 725 articles, of which 30 articles were included for full study after applying the exclusion criteria. From these articles 94 FOP patients were evaluated for gender, age, presence and age at which HO started in the maxillofacial region, location of HO, whether HO was caused spontaneous or traumatic and maximum mouth opening. Formation of HO is slightly more common in female patients compared to male patients, but the age of HO onset or the maximum mouth opening does not differ between genders. Trauma-induced HO occurred at a significantly younger age than spontaneous HO. Interestingly, a difference in maximum mouth opening was observed between the different ossified locations in the maxillofacial region, with ossification of the masseter muscle resulting in the smallest and ossification of the zygomatic arch resulting in the largest maximum mouth opening. This review revealed that the location of the maxillofacial region affected by HO determines the degree of limitations of the maximum mouth opening. This finding may be important for establishing clinical guidelines for the dental management of FOP patients.

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