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1.
Orthop Surg ; 2024 Jul 09.
Artículo en Inglés | MEDLINE | ID: mdl-38982649

RESUMEN

OBJECTIVE: The revision procedure for failure of internal fixation after thoracolumbar fracture is controversial. Combined anterior and posterior surgery is associated with higher risk more intraoperative bleeding and tissue damage. The success rate of simple anterior surgery needs further confirmation, and posterior surgery lacks stability of internal fixation. This study evaluates the feasibility and surgical effect of multi-rod constructs in the revision of thoracolumbar fractures. METHODS: Eleven patients with thoracolumbar fractures who underwent previous construct failure and were treated with revision and internal fixation with the multi-rod technique from March 2017 to September 2018 were analyzed. The original internal fixation was removed and replaced in the medial insertion of satellite rods and bone graft. The average follow-up time was 15.97 months. The intraoperation blood loss, the time of the operation, activation and discharge and the rate of rod fracture were calculated. The sagittal Cobb angle before revision, after revision and at the last follow-up were compared. The clinical effect was evaluated by visual analogue scale (VAS) and Oswestry Disability Index questionnaire (ODI). RESULTS: The average operation time was 107 min, the intraoperative blood loss was 131.81 mL, the active time was 1.59 days, and the discharge time was 10.89 days. No rod fractured again during the follow-up period. The paired t-test was used to compare the Cobb angle, VAS score, and ODI before and after surgery. There was significant difference in the sagittal Cobb angle between the pre-revision and the posterior sagittal position (p = 0.000), and no significant difference was found between post-revision and last follow-up (p = 0.551). VAS and ODI were greatly improved at the last follow-up. CONCLUSION: The literature on revision of thoracolumbar fractures is insufficient and comprises varying opinions. This paper proposes a new treatment option. The application of the multi-rod constructs in the revision of thoracolumbar fractures is safe, simple, and effective and might provide guidance for future clinical work.

2.
Soc Sci Med ; 355: 117090, 2024 Jul 05.
Artículo en Inglés | MEDLINE | ID: mdl-39018996

RESUMEN

Housing is a pressing problem worldwide and a key determinant of health and wellbeing. The right to adequate housing, as a pillar of the right to an adequate standard of living, means more than a roof to live under. Adequate means the dwelling must fulfill material functions and psychosocial functions, thus contributing to dwellers health and wellbeing. Social housing policies aim to fulfill the right to housing, but frequently fail in fulfilling the right to it being adequate. This study capitalizes on the implementation of a national urban regeneration program in two social housing villas in central Chile (one in Santiago, in the central valley, the other in Viña del Mar, a coastal city) to run a natural experiment assessing the impact of dwelling renovation on several dimensions of perceived habitability and housing satisfaction among the -mostly female-household homemakers. We use 5 waves of survey data collected with a step-wedge design to estimate the association between a time-varying exposure status (the intervention) and 7 binary outcomes for habitability and 5 for housing dissatisfaction, including overall housing satisfaction. We use Poisson regression models with robust variance and a random intercept at the respondent level. At baseline, reports of poor habitability and dissatisfaction across all features were markedly high, the highest levels of dissatisfaction being with acoustic insulation and dwelling size in both villas, and with indoor temperature in Santiago. The intervention resulted in statistically significant and markedly large improvements in reported habitability and dissatisfaction relative to those housing components targeted by the intervention, as well as with overall dwelling satisfaction in both study cases. Implications are, first, that the policy response to quantitative housing deficits must not overlook housing quality; second, that housing renovation appears as a promising intervention for qualitative housing crises; third, that while improvements in habitability and satisfaction are specific to the interventions in place, overall housing satisfaction can improve in more limited, tailored, dwelling renovation interventions. Social housing renovation in Latin America appears as a promising intervention to improve quality of life among the urban poor dwellers and reduce inequalities in health related to housing conditions.

3.
Environ Res ; 257: 119332, 2024 Sep 15.
Artículo en Inglés | MEDLINE | ID: mdl-38838753

RESUMEN

Indoor air quality is a critical factor influencing athletic performance, particularly in professional sports settings, yet its impact remains underexplored. This study utilizes a panel dataset from 2516 Chinese Basketball Association (CBA) matches across 20 cities in China between 2014 and 2019. We integrate daily air pollution metrics with player efficiency ratings (PER) to investigate the effects of air quality on individual performance. We find that a 10% increase in the air quality index (AQI) corresponds to a 1.4223 decrease in PER, indicating a strong negative effect of poor air quality on player productivity. Different pollutants have varying effects, with some exacerbating the decline in both overall performance and precision in tasks. Notably, older players and international players exhibit greater resilience to air pollution. These insights contribute to the development of a comprehensive index for assessing work efficiency under varying air quality conditions and suggest targeted strategies to mitigate the negative impacts of air pollution in competitive athletic settings.


Asunto(s)
Contaminación del Aire Interior , Contaminación del Aire Interior/análisis , Contaminación del Aire Interior/prevención & control , China , Humanos , Contaminantes Atmosféricos/análisis , Ciudades , Monitoreo del Ambiente , Rendimiento Atlético , Baloncesto
4.
Environ Pollut ; 349: 123920, 2024 May 15.
Artículo en Inglés | MEDLINE | ID: mdl-38582187

RESUMEN

This research endeavors to elevate indoor air quality within aging school environments by concentrating on refining interior finishing materials and windows. Renovations, encompassing window and floor remodeling in classrooms, aim to mitigate particulate matter (PM) infiltration and enhance air exchange rates. Utilizing SPS30 sensors for the analysis of 0.3-2.5 µm particles, with a focus on their implications for human health, the study evaluated air exchange rates, deposition rates, infiltration rates, and particle generation during classroom activities. Post-renovation results demonstrated a noteworthy decrease in air exchange rates, indicating an enhancement in airtightness. The investigation delves into particle generation with various flooring materials, accentuating the importance of opting for durable and low-particle-generating alternatives. Health risk assessments, considering multiple exposure routes (inhalation, dermal contact, and ingestion), revealed reduced risks post-renovation, particularly for children. To further optimize indoor air quality, the study suggests the implementation of air purification systems. Examination of PM generation during student activities showcased a substantial reduction post-renovation. This study underscores the positive influence of architectural enhancements on indoor air quality while acknowledging the necessity for holistic solutions and continuous research.


Asunto(s)
Contaminación del Aire Interior , Material Particulado , Instituciones Académicas , Contaminación del Aire Interior/estadística & datos numéricos , Contaminación del Aire Interior/análisis , Material Particulado/análisis , Humanos , Pisos y Cubiertas de Piso , Monitoreo del Ambiente/métodos , Contaminantes Atmosféricos/análisis
5.
BMC Public Health ; 24(1): 1056, 2024 Apr 16.
Artículo en Inglés | MEDLINE | ID: mdl-38622675

RESUMEN

BACKGROUND: Holistic housing renovations combine physical housing improvements with social and socioeconomic interventions (e.g. referral to social services, debt counselling, involvement in decision-making, promoting social cohesion). In a deprived neighbourhood in Utrecht, the Netherlands, this paper examined residents' and professionals' experiences, ideas, and perceptions regarding holistic housing renovation, its health effects, and underlying mechanisms explaining those effects. METHODS: Semi-structured in-depth interviews were conducted with 21 social housing residents exposed to holistic housing renovation, and 12 professionals involved in either the physical renovation or social interventions implemented. Residents were interviewed in various renovation stages (before, during, after renovation). Transcripts were deductively and inductively coded using qualitative software. RESULTS: Residents experienced and professionals acknowledged renovation stress caused by nuisance from construction work (noise, dust), having to move stuff around, and temporary moving; lack of information and control; and perceived violation of privacy. Involvement in design choices was appreciated, and mental health improvement was expected on the long term due to improved housing quality and visual amenity benefits. Social contact between residents increased as the renovation became topic for small talk. Few comments were made regarding physical health effects. The interviews revealed a certain amount of distrust in and dissatisfaction with the housing corporation, construction company, and other authorities. CONCLUSIONS: Renovation stress, aggravated by lack of information and poor accessibility of housing corporation and construction company, negatively affects mental health and sense of control. Potential stress relievers are practical help with packing and moving furniture, and increased predictability by good and targeted communication. Social interventions can best be offered after renovation, when residents live in their renovated apartment and the nuisance and stress from the renovation is behind them. Social partners can use the period leading up to the renovation to show their faces, offer practical help to reduce renovation stress, and increase residents' trust in their organization and authorities in general. This might also contribute to residents' willingness to accept help with problems in the social domain after renovation.


Asunto(s)
Vivienda , Características de la Residencia , Humanos , Países Bajos , Salud Mental
6.
Heliyon ; 10(6): e27672, 2024 Mar 30.
Artículo en Inglés | MEDLINE | ID: mdl-38510033

RESUMEN

The renovation of urban residential buildings in the context of urban renewal presents social challenges due to the involvement of diverse stakeholders and complex interest relations. This study identifies 28 critical success factors (CSFs) and 9 stakeholders, drawing insights from literature and on-site research of 45 old residential renewal projects in Jiangsu Province, China. Employing social network analysis, the intricate interplay between CSFs and stakeholders is explored, emphasizing the imperative for collaborative governance and elucidating governance mechanism principles. Focusing on stakeholders' resource contributions to transformation projects, the study devises a collaborative governance mechanism based on the specific types of resources required to support each CSF. This approach ensures that CSFs receive the necessary resources, enhancing project success. The paper concludes by outlining nine governance mechanisms and their implementation paths, anchored in the relationships between 13 CSFs and their respective stakeholders.

7.
Environ Sci Pollut Res Int ; 31(6): 9011-9030, 2024 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-38183549

RESUMEN

Although the government highly focuses on old residential building energy-saving renovation (ORBESR), many hinders still exist and the efficiency of it is still low. This paper proposes a four-party evolutionary game model to study the impact of relative stakeholders' choices, involving developers, residents, neighborhood councils, and governments. Using this model, this paper studies what influences the conflicts between developers and residents take on the efficiency of ORBESR. In addition, what influence the residents, neighborhood councils, and developers' strategies will take on the ORBESR under the condition of evolutionary stability strategy. This paper finally concludes that governments could propose high penalties first to accelerate the stability of the system, then suitable subsidies to relieve the financial burden and to achieve high efficiency. The governments could provide a suitable plan for residents' investment to promote residents' participation. The neighborhood councils arouse the ways and facilities to help residents understand and participate in the ORBESR and try to solve the conflicts between developers and residents can improve the residents' participation and the developers' willingness to implement the ORBESR.


Asunto(s)
Gobierno , Características de la Residencia , Inversiones en Salud , China
8.
J Environ Manage ; 351: 119908, 2024 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-38169254

RESUMEN

The construction industry generates a substantial volume of solid waste, often destinated for landfills, causing significant environmental pollution. Waste recycling is decisive in managing waste yet challenging due to labor-intensive sorting processes and the diverse forms of waste. Deep learning (DL) models have made remarkable strides in automating domestic waste recognition and sorting. However, the application of DL models to recognize the waste derived from construction, renovation, and demolition (CRD) activities remains limited due to the context-specific studies conducted in previous research. This paper aims to realistically capture the complexity of waste streams in the CRD context. The study encompasses collecting and annotating CRD waste images in real-world, uncontrolled environments. It then evaluates the performance of state-of-the-art DL models for automatically recognizing CRD waste in-the-wild. Several pre-trained networks are utilized to perform effectual feature extraction and transfer learning during DL model training. The results demonstrated that DL models, whether integrated with larger or lightweight backbone networks can recognize the composition of CRD waste streams in-the-wild which is useful for automated waste sorting. The outcome of the study emphasized the applicability of DL models in recognizing and sorting solid waste across various industrial domains, thereby contributing to resource recovery and encouraging environmental management efforts.


Asunto(s)
Industria de la Construcción , Aprendizaje Profundo , Administración de Residuos , Administración de Residuos/métodos , Materiales de Construcción , Residuos Sólidos , Residuos Industriales/análisis , Reciclaje , Industria de la Construcción/métodos
9.
Artículo en Alemán | MEDLINE | ID: mdl-38193913

RESUMEN

The conversion of industrial buildings into residential space requires special consideration of the inherited building fabric and associated pollutants. Due to the previous industrial use at contaminated sites, certain pollutants may play a significant role that are normally not the focus of refurbishments activities of residential spaces. In order to comply with the increased requirements with respect to indoor air quality in residential spaces, and to avoid unnecessary efforts and costs of amendments to the refurbishment, the Indoor Air Hygiene Commission (IRK) provides advice on how to prepare the conversion of commercial buildings so that healthy living conditions are ensured.


Asunto(s)
Contaminación del Aire Interior , Contaminantes Ambientales , Alemania , Estado de Salud , Higiene
10.
AORN J ; 119(1): 72-80, 2024 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-38149898

RESUMEN

Hospital construction and renovation is an ongoing occurrence in the health care setting. The recently updated AORN "Guideline for design and maintenance of the surgical suite" provides perioperative nurses with information on the layout design and maintenance of perioperative spaces; safety measures to use during construction and renovation; monitoring and maintenance of the heating, ventilation, and air conditioning; and how to respond to unintended utility failures. This article provides an overview of the guideline and discusses recommendations for the interdisciplinary team, planning and designing the surgical suite, construction-related environmental contamination, ORs, and OR maintenance. It also includes a scenario describing specific concerns associated with the construction of an additional OR. Perioperative nurses should review the guideline in its entirety and apply the recommendations when participating in perioperative construction and renovation projects.


Asunto(s)
Aire Acondicionado , Ventilación , Humanos
11.
Behav Sci (Basel) ; 13(11)2023 Nov 13.
Artículo en Inglés | MEDLINE | ID: mdl-37998672

RESUMEN

Intergenerational integration has given rise to a novel aging paradigm known as all-age communities, which is garnering international attention. In China, the aging population and the implementation of the three-child policy have resulted in increased demand for retirement and childcare services among residents in older neighborhoods. Consequently, there is a pressing need to retrofit these older neighborhoods to accommodate all-age living arrangements given the high demand they generate. Therefore, this study undertakes research interviews with residents and constructs an exploratory theoretical model rooted in established theory. To assess the significance of our model, we employ Smart PLS 3.0 based on 297 empirical data points. Our findings indicate that anxiety has a significant negative effect on payment behavior; objective perception, willingness to pay, and government assistance exert significant positive effects on payment behavior. By comprehensively analyzing the mechanisms underlying residents' payment behavior, this study provides valuable insights for the government for promoting the aging process within communities and formulating effective transformation policies.

12.
Environ Monit Assess ; 195(12): 1524, 2023 Nov 23.
Artículo en Inglés | MEDLINE | ID: mdl-37994965

RESUMEN

One of the major present challenges in the building sector is to construct sustainable and low-energy buildings with a healthy, safe, and comfortable environment. This study is designed to explore long-term impacts of indoor environmental quality (IEQ) parameters in a historic technical school building on the health and comfort of students. The main objective is to identify environmental problems in schools and to direct public policy towards the enhancement of in-service historic buildings. The collected data on five consecutive days in various seasons from five different classrooms indicate allergy in 45% and asthma in 10% of students. Environmental factors, such as temperature, draught, noise, or light, affected 51% of students' attention. Low temperature, unpleasant air, noise, and draught were found to be the most frequent concerns for students. The lowest temperature was measured during spring at 17.6 °C, the lowest humidity of 21.1% in winter, the largest CO2 amount in the air in autumn at 2041 ppm level, and the greatest total volatile organic compounds (TVOC) as 514 µg/m3. The experimental and statistical analysis results suggest the necessity of a comprehensive restoration of the building with a focus on enhancement of IEQ as well as replacement of old non-standard materials. An effective ventilation system is also necessary. The building requires major renovations to preserve its historic features while safeguarding the well-being and comfort of students and staff. Further research is needed on acoustics, lighting, and energy factors as well as the health effects of old building materials.


Asunto(s)
Monitoreo del Ambiente , Hipersensibilidad , Humanos , Eslovaquia , Estaciones del Año , Instituciones Académicas
13.
Materials (Basel) ; 16(18)2023 Sep 12.
Artículo en Inglés | MEDLINE | ID: mdl-37763458

RESUMEN

Renovation of dirt roads requires a reliable and durable work tool. This article includes the methodology of field and bench tests as well as the results of these tests and conclusions for cutters used for dirt road renovation. The main novelty of the research presented in this article was to determine the wear mechanisms occurring during field and laboratory tests, to determine the differences in wear levels and the cost of renovation of one kilometer of dirt road. Calculations of the efficiency of replacing these working elements and the cost of operating various cutters per km are also presented. The lowest mass loss was characterized by milling cutters Ø25 mm mounted on an expansion sleeve and amounted to 130 g. The dominant wear mechanism that was observed after the renovation of dirt roads was micro-scraping and micro-bruising. For this variant, the cost per 1 km of road renovation was also the lowest and amounted to about PLN 2.

14.
Sci Total Environ ; 904: 166915, 2023 Dec 15.
Artículo en Inglés | MEDLINE | ID: mdl-37690765

RESUMEN

Ground hardening in urban areas increases the risk of thermal enrichment in surface rainwater runoff. Moreover, the thermal pollution from rainwater runoff has become an important problem that damages the urban aquatic environment. Current studies have focused mainly on the potential hazard caused by runoff thermal pollution to aquatic microorganisms. However, there are few studies on the efficacy of controlling runoff thermal load through low-impact development (LID) and renovation in urban areas. The effects of LID modification were evaluated by monitoring the characteristics of the runoff thermal load on each underlying surface in the study area and conducting laboratory-scale bioretention experiments. The results showed that the initial thermal effect of each underlying surface was significant after the start of rainfall, based on the thermal load. Ceramic granules are remarkable bioretention fillers. Their average heat load and volume reduction rates are 55.6 % and 32.7 %, respectively. After LID modification, the thermal load of surface runoff in the study area decreased to 73.42 % under similar rainfall conditions. After the secondary treatment of the bioretention facility, the total thermal load of the outflow facility was 31.40 % of that before renovation. The peak thermal load reduced by 69.15 % and was delayed for 10 min. The control effect differed statistically.

15.
Environ Health Insights ; 17: 11786302231181489, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-37456908

RESUMEN

Background: The ambient and indoor environment are pivotal to our health. We spend most of our time indoors within our home, why our home is where we are most exposed to indoor pollutants and indoor air quality (IAQ). Populations within social housing areas are more vulnerable due to advanced age, co-morbidity and social economic status. Commonly, studies within social housing are cross-sectional, few Nordic longitudinal studies exist, and fewer studies combine quantitative and qualitative measurements in a mixed method approach. Method: This research proposal provides an extensive detailed description of the design and methodology of the HOME-Health study. The study is a longitudinal study and is a natural experiment employing structured surveys, objective measurements of indoor air parameters, lung function test and qualitative semi-structured interviews. Data collection are conducted seasonally (winter and summer), before and after building energy renovation (BER). Generalisability: The study population before BER (n = 432) was explored and found similar to the Danish social housing population in terms of age, gender, persons per apartment and migration status. Future analyses should be stratified by multi-family apartments and terraced houses. Research aim: The aim of the HOME-Health study is to provide knowledge about residents' seasonal state of health, perception of indoor enviromental quality (IEQ), IEQ-related behaviours and practices, and objective measurements of IAQ before and after BER. By applying a design with repeated measurement before and after BER, and combining both objective and subjective quantitative as well as qualitative data the study is expected to create in-depth knowledge. Future results will provide evidence of both energy-savings and non-energy savings from different BER projects. Knowledge which are expected to benefit future renovation projects within social housing areas.

16.
Sci Total Environ ; 894: 164940, 2023 Oct 10.
Artículo en Inglés | MEDLINE | ID: mdl-37343888

RESUMEN

In this study, we use the approach of geospatial and temporal (GeoST) mapping of urban mobility to evaluate the speed-time-acceleration profile (dynamic status) of passenger cars. We then use a pre-developed model, fleet composition and real-world emission factor (EF) datasets to translate vehicles dynamics status into real-urban fuel consumption (FC) and exhaustive (CO2 and NOx) emissions with high spatial (15 m) and temporal (2 h) resolutions. Road transport in the West Midlands, UK, for 2016 and 2018 is the spatial and temporal scope of this study. Our approach enables the analysis of the influence of factors such as road slope, non-rush/rush hour and weed days/weekends effects on the characteristics of the transport environment. The results show that real-urban NOx EFs reduced by more than 14 % for 2016-18. This can be attributed to the increasing contribution of Euro 6 vehicles by 63 %, and the increasing contribution of diesel vehicles by 13 %. However, the variations in the real-urban FC and CO2 EFs are less significant (±2 %). We found that the FC estimated for driving under the NEDC (National European Driving Cycle) is a qualified benchmark for evaluating real-urban FCs. Considering the role of road slope increases the estimated real-urban FC, and NOx, and CO2 EFs by a weighted average of 4.8 %, 3.9 %, and 3.0 %, respectively. Time of travel (non-rush/rush hour or weed days/weekends) has a profound effect on vehicle fuel consumption and related emissions, with EFs increasing in more free-flowing conditions.

17.
Artículo en Chino | MEDLINE | ID: mdl-37248087

RESUMEN

Objective: To explore the sound insulation, sound absorption and other noise reduction transformation methods in a noise workshop handover control room. Methods: In December 2021, through the occupational health investigation and on-site testing of the handover control room of a noise workshop, the causes of excessive noise were analyzed, and the transformation design scheme to reduce noise was proposed and the effect was analyzed. Results: Before the transformation, the peak frequency band noise intensity of the noise workshop handover control room was 112.8 dB (A), and the peak frequency was 1000 Hz. After noise reduction, the theoretical calculated control value was 61.0 dB (A), and the measured noise intensity was 59.8 dB (A) . Conclusion: The noise intensity of the handover control room is reduced after noise reduction, which is in line with the contact limit requirements of the control room in GBZ 1-2010 "Hygienic Standards for the Design of Industrial Enterprises", and has reference significance for noise control engineering.


Asunto(s)
Ruido en el Ambiente de Trabajo , Salud Laboral , Ruido/prevención & control , Industrias , Estándares de Referencia , Higiene , Ruido en el Ambiente de Trabajo/prevención & control
18.
Data Brief ; 48: 109225, 2023 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-37228417

RESUMEN

This article includes data collected from public and private buildings in Latvia as part of several projects/tenders funded from the governmental Climate Change Financial Instrument (KPFI) of Republic of Latvia. The data provided consists of information on 445 projects, the activities performed therein, as well as numerical data on CO2 emission and energy consumption before and after the projects' implementation. Data cover a period from 2011 to 2020 for various types of buildings. Given the amount, the completeness and the accuracy of data accompanied by qualitative and quantitative information on the funded projects, the datasets could be relevant for evaluating the energy efficiency of the implemented activities and the levels of CO2 and energy reduction. The reported figures could be used for further research on the field of energy performance of buildings and buildings' refurbishments. They could be also taken as case studies by other buildings that plan to implement similar actions.

19.
Environ Pollut ; 329: 121582, 2023 Jul 15.
Artículo en Inglés | MEDLINE | ID: mdl-37062407

RESUMEN

The hazardous effects of air pollution on the human body are of grave concern, particularly the rising levels of 2.5 µm-particulate matter. Children are more susceptible to the lethal effects of particulate matter (PM) than adults. In this study, a case study of architectural renovation (ARCH-R) and facility renovation (FAC-R) was conducted in a school by focusing on the exit and entrance gates. In addition, the PM influx rate was evaluated. To evaluate the influx rate of PM, opening/closing recognition equipment and particle sensors were utilized. Following the renovation, the result was evaluated. During the daytime, the air curtain led to a reduction in the influx rate of PM of approximately 8% when the door was open. During the nighttime, it was confirmed that the fine dust influx rate was reduced through reinforcement of the door. However, regarding using these two measures in combination, it was confirmed that the concentration of PM increased in the corridor when the air curtain was operated while the door was closed. It was confirmed that both ARCH-R and FAC-R are necessary for controlling the influx of fine dust from the outdoor air. Appropriate operating guidelines should be provided for school operators.


Asunto(s)
Contaminantes Atmosféricos , Contaminación del Aire Interior , Niño , Humanos , Material Particulado/análisis , Contaminantes Atmosféricos/análisis , Tamaño de la Partícula , Contaminación del Aire Interior/análisis , Monitoreo del Ambiente , Polvo , Instituciones Académicas
20.
Environ Health ; 22(1): 37, 2023 04 18.
Artículo en Inglés | MEDLINE | ID: mdl-37072765

RESUMEN

BACKGROUND: Congenital heart disease (CHD) is the most prevalent birth defect in recent decades. The aim of this research was to examine the association between maternal housing renovation exposure during the periconceptional period and isolated congenital heart disease (CHD) in their offspring. METHODS: A multi-hospitals case-control study was conducted from six tertiary A hospitals in Xi'an, Shaanxi, Northwest China based on questionnaires and interviews to address this question. The cases included fetuses or newborns diagnosed with CHD. Controls consisted of healthy newborns without birth defects. In total, 587 cases and 1180 controls were enrolled in this study. The association between maternal periconceptional housing renovation exposure and isolated CHD for offspring was assessed by estimating odds ratios (OR) with multivariate logistic regression models. RESULTS: After adjusting for potential confounding variables, it was found that maternal exposure to home improvement projects was associated with a higher probability of isolated CHD in offspring (adjusted OR: 1.77, 95% CI: 1.34, 2.33). Additionally, the risk of the ventricular septal defect (VSD) and patent ductus arteriosus (PDA) for CHD types was significantly associated with maternal exposure to housing renovations (VSD: adjusted OR = 1.56, 95% CI: 1.01, 2.41; PDA: adjusted OR = 2.50, 95% CI: 1.41, 4.45). CONCLUSIONS: Our study suggests that maternal exposure to housing renovation during the periconceptional period was associated with an increased risk of isolated CHD in offspring. Consequently, it would be beneficial to avoid living in a renovated home from 12 months before pregnancy through the first trimester to lower isolated CHD in infants.


Asunto(s)
Cardiopatías Congénitas , Exposición Materna , Lactante , Embarazo , Femenino , Humanos , Recién Nacido , Exposición Materna/efectos adversos , Estudios de Casos y Controles , Vivienda , Factores de Riesgo , Cardiopatías Congénitas/epidemiología , Cardiopatías Congénitas/etiología
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