The association between ballroom dance training and empathic concern: Behavioral and brain evidence.

Dance is unique in that it is a sport and an art simultaneously. Beyond improving sensorimotor functions, dance training could benefit high-level emotional and cognitive functions. Duo dances also confer the possibility for dancers to develop the abilities to recognize, understand, and share the thoughts and feelings of their dance partners during the long-term dance training. To test this possibility, we collected high-resolution structural and resting-state functional magnetic resonance imaging (MRI) data from 43 expert-level ballroom dancers (a model of long-term exposure to duo dance training) and 40 age-matched and sex-matched nondancers, and measured their empathic ability using a self-report trait empathy scale. We found that ballroom dancers showed higher scores of empathic concern (EC) than controls. The EC scores were positively correlated with years with dance partners but negatively correlated with the number of dance partners for ballroom dancers. These behavioral results were supported by the structural and functional MRI data. Structurally, we observed that the gray matter volumes in the subgenual anterior cingulate cortex (ACC) and EC scores were positively correlated. Functionally, the connectivity between ACC and occipital gyrus was positively correlated with both EC scores and years with dance partners. In addition, the relationship between years with dance partners and EC scores was indirect-only mediated by the ACC-occipital gyrus functional connectivity. Therefore, our findings provided solid evidence for the close link between long-term ballroom dance training and empathy, which deepens our understanding of the neural mechanisms underlying this phenomenon.

The different role of trait empathy and state social exclusion empathy on subsequent feelings about gambling outcome：Evidence from event-related potentials and time-frequency decompositions.

Empathy plays an essential role in determining how we understand and respond to others' emotional experiences. Previous studies have mainly focused on the influencing factors of physical pain and monetary loss empathy, as well as on their effects on subsequent feelings. However, little is known about social pain empathy and its influence on subsequent feelings, and the role of personal trait empathy. In this study, we performed Cyberball Games and gambling tasks to explore the effect of social exclusion empathy on subsequent feelings for gambling outcomes (others' losses and gains) by analyzing the brain activity of excluded and non-excluded players at the gambling outcome feedback stage. It was found that both feedback-related negativity (FRN) and theta-band oscillatory are more negative for loss outcome than gain for the excluded players, while these effects cannot be found for the non-excluded players. Furthermore, we only observed a larger P300 amplitude in the gain outcome than that of loss, regardless of the players' role. More interestingly, we found state social pain empathy is negatively correlated with the d-FRN amplitude under non-excluded conditions, while trait empathy is positively correlated with P300 amplitude regardless of the players' role. These results provide insight into the different roles of state social pain empathy and trait empathy on subsequent gambling outcomes. Furthermore, different from previous studies, the current results show that d-FRN could reflect the state empathy discrepancy rather than the biomarker of state empathy.

Cognitive flexibility as a protective factor for empathy.

Although cognitive flexibility has always been considered essential to empathy, the relevant findings have been inconsistent. Inconsistent results may be because cognitive flexibility is a multi-level structure, while empathy is also a multilayer structure, and there are differences in how researchers define and measure cognitive flexibility. Therefore, the study explores the relationship between cognitive flexibility and empathy from a multi-dimensional perspective. This study involved 105 China students aged between 18 and 22 (M age = 20.26, SD = 2.00) who completed the Cognitive Flexibility Scale (cognitive flexibility trait, cognitive flexibility at the individual level), perspective-switching flexibility task (perspective-switching flexibility, cognitive flexibility at the cognitive level), the Interpersonal Reactivity Index scale (IRI, traits empathy), Multi-dimensional Empathy Test (state empathy), 2-back task (inhibitory control), and Stroop task (working memory). After controlling for additional variables, the results showed that: (1) Cognitive flexibility traits negatively predicted trait cognitive (IRI-PT) and affective empathy (IRI-EC). (2) The Other/Self perspective-switching flexibility negatively predicted the affective component of state empathy. (3) Cognitive flexibility traits and Other/Self perspective-switching flexibility negatively predicted empathy even after controlling for one of these. The study's results suggested that cognitive flexibility negatively predicts empathy and is a protective factor for reducing the cost of empathy and promoting emotion regulation.

Individualized Prediction of Females' Empathic Concern from Intrinsic Brain Activity within General Network of State Empathy.

Empathy can be measured based on behavioral tasks and self-report scales, which have been used to characterize the state and trait empathy, respectively, in previous studies. The neural correlates of state empathy have been deeply investigated, whereas the association between trait empathy and brain activity remains unclear. Thus, this study employed multiple variate pattern analysis (MVPA) to explore whether intrinsic brain activity (IBA) within state-empathy-related regions was associated with trait empathy. Meta-analysis of empathy-related fMRI experiments identified a general network underlying state empathy, which is located in the bilateral supplementary motor area (SMA) extending to the middle cingulate cortex (MCC) and left anterior insula (AI) and extending to the inferior frontal gyrus (IFG). The subsequent MVPA found that empathic concern can be predicted through the IBA of the general network at the female individual level (i.e., the fractional amplitude of low-frequency fluctuations and regional homogeneity). Based on the resting state fMRI (rs-fMRI), these results further support the involvement of SMA/MCC and AI/IFG in empathy. Meanwhile, the significant predictive association between IBA and trait empathy offers new insights into the general component of empathy, which may indicate the potential of using rs-fMRI to achieve the objective measurement of empathic ability.

Improving attitudes toward electroconvulsive therapy.

AIMS AND METHOD: Electroconvulsive therapy (ECT) often causes fear in the general public because of media representation and negative reported side-effects. This study evaluates a new video focusing on experiences of ECT and how this can aid communicating medical information to the public. Knowledge and attitudes toward ECT after watching the video were compared with a group that received no information and a group that read the current NHS leaflet on ECT. The role of empathy was also considered as a covariate. RESULTS: The video was the only condition found to positively affect knowledge and attitudes toward ECT. The video was especially beneficial to those that possessed low perspective-taking trait empathy. CLINICAL IMPLICATIONS: These findings demonstrate the video improved knowledge and attitudes toward ECT compared with current material or no information. We suggest that the addition of personal experiences to public information adds perspective, improving overall attitudes toward health treatments.

Trait Empathy Shapes Neural Responses Toward Sad Music.

Individuals with a predisposition to empathize engage with sad music in a compelling way, experiencing overall more pleasurable emotions. However, the neural mechanisms underlying these music-related experiences in empathic individuals are unknown. The present study tested whether dispositional empathy modulates neural responses to sad compared with happy music. Twenty-four participants underwent fMRI while listening to 4-min blocks of music evoking sadness or happiness. Using voxel-wise regression, we found a positive correlation between trait empathy (with scores assessed by the Interpersonal Reactivity Index) and eigenvector centrality values in the ventromedial prefrontal cortex (vmPFC), including the medial orbitofrontal cortex (mOFC). We then performed a functional connectivity (FC) analysis to detect network nodes showing stronger FC with the vmPFC/mOFC during the presentation of sad versus happy music. By doing so, we identified a "music-empathy" network (vmPFC/mOFC, dorsomedial prefrontal cortex, primary visual cortex, bilateral claustrum and putamen, and cerebellum) that is spontaneously recruited while listening to sad music and includes brain regions that support the coding of compassion, mentalizing, and visual mental imagery. Importantly, our findings extend the current understanding of empathic behaviors to the musical domain and pinpoint sad music as an effective stimulus to be employed in social neuroscience research.

Trait Respect Is Linked to Reduced Gray Matter Volume in the Anterior Temporal Lobe.

Respect is a positive other-oriented social emotion upon the recognition of excellence in others. We previously reported that respect-related brain activity in the left anterior temporal lobe (ATL). Since brain activity and structure are often involved in common cognitive functions, we investigated the morphological properties of the left ATL using voxel-based morphometry analysis. We found an association of trait respect with reduced gray matter volume (GMV) in part of the left ATL. Moreover, since the ATL is involved in general conceptual knowledge, we investigated the relationships between other social emotions with similar properties as respect and the GMV of the left ATL. We observed an association of reduced GMV with empathic concern, which is an other-oriented and affective aspect of trait empathy. Our findings indicated an association of the left ATL with other-oriented and affective aspect of social emotions.

The social curse: Evidence for a moderating effect of shared social identity on contagious stress reactions.

Contagious stress describes the transmission of a stress response from a distressed individual (target) to an uninvolved observer. Building on social identity theory, we hypothesize that a shared social identity between the observer and the target as compared to a personal identity increases the likelihood of contagious endocrine and psychological stress responses. Participants underwent the experiment in groups of four or five individuals. After experimentally inducing either a shared social identity or a personal identity, one participant in each group (Ntarget = 27) was randomly chosen to undergo the Trier Social Stress Test (TSST), while being observed by the rest of the group (Nobserver = 89). Salivary cortisol and psychological stress responses were assessed repeatedly during the experiment. As predicted, the likelihood of cortisol stress reactions was significantly higher in the social identity condition (25 %) as compared to the personal identity condition (7 %). No effect of our manipulation on psychological stress responses was found. We also tested whether observers' trait empathy moderates contagious stress and found no support for this moderation.

On the Enjoyment of Sad Music: Pleasurable Compassion Theory and the Role of Trait Empathy.

Drawing on recent empirical studies on the enjoyment of nominally sad music, a general theory of the pleasure of tragic or sad portrayals is presented. Not all listeners enjoy sad music. Multiple studies indicate that those individuals who enjoy sad music exhibit a particular pattern of empathic traits. These individuals score high on empathic concern (compassion) and high on imaginative absorption (fantasy), with only nominal personal distress (commiseration). Empirical studies are reviewed implicating compassion as a positively valenced affect. Accordingly, individuals who most enjoy sad musical portrayals experience a pleasurable prosocial affect (compassion), amplified by empathetic engagement (fantasy), while experiencing only nominal levels of unpleasant emotional contagion (commiseration). It is suggested that this pattern of trait empathy may apply more broadly, accounting for many other situations where spectators experience pleasure when exposed to tragic representations or portrayals.

Linking brain structure and activation in anterior insula cortex to explain the trait empathy for pain.

The ability to perceive, understand, and react to the feelings of others' pain is referred to as empathy for pain which is composed of two components, affective-perceptual empathy and cognitive-evaluative empathy. Recent reviews on the neural mechanisms of empathetic pain showed the anterior insula (AI) cortex as a core circuit for empathy. However, little is known about the modulation of brain anatomy and empathic responses by trait measures of empathy (trait empathy). Thus, we investigated whether individual variation in the personality trait of empathy is associated with individual variation in the structure of specific brain regions using voxel-based morphometry (VBM). We further investigated the relationship between the trait empathy and the activity of the same regions using state measures of empathy for pain in a trial-by-trial fashion in the given situation. VBM analysis indicated a small but significant negative relationship between trait empathy and gray matter volume in the bilateral AI. Functional MRI study further demonstrated that experimentally induced activity of the bilateral AI during state empathy for pain was also correlated with trait empathy. An asymmetry exists between the right and left AI between the affective and cognitive empathy. The right AI was found to be involved in the affective-perceptual form of empathy and the left AI was active in cognitive-evaluative forms of empathy. The interindividual differences in trait empathy may be reflected both in the state empathy and more stable brain structure difference.

Clarifying the relationship between trait empathy and action-based resonance indexed by EEG mu-rhythm suppression.

Sensorimotor resonance, the vicarious activation of the sensory motor system during observation of another's actions, is thought to contribute to important social functions including empathy. Previous research has shown that sensorimotor resonance, as measured by suppression of the electrophysiological (EEG) mu rhythm, is predicted by trait empathy, but findings are inconsistent. Here we report data from a high-powered study (N = 252) to clarify the relationship between sensorimotor resonance as indexed by mu suppression during action observation and trait empathy as measured by the well-established Interpersonal Reactivity Index (IRI). Our initial pre-registered analyses at central electrode locations indicate that sensorimotor resonance is unrelated to general trait empathy or its sub-facets, however, these effects could not be isolated from attention-related occipital alpha. An additional non-registered analysis using Independent Component Analysis (ICA) to look at the isolated central mu-component clarified the relationship. Results confirmed the lack of a relationship between the mu-component and the perspective taking, personal distress, or fantasy facets of the IRI, but suggest a possible association with empathic concern such that greater resonance is associated with greater empathic concern. These results question the previously assumed relationship between trait empathy and sensorimotor resonance and highlight the need to investigate experience sharing tendencies in the context of simulation-based resonance.

Autistic Traits and Prosocial Behaviour in the General Population: Test of the Mediating Effects of Trait Empathy and State Empathic Concern.

Although the core characteristics associated with autistic traits are impaired social interactions, there are few studies examining how autistic traits translate into prosocial behaviour in daily life. The current study explored the effect of autistic traits on prosocial behaviour and the mediating role of multimodal empathy (trait empathy and state empathic concern). The results showed that autistic traits reduced prosocial behaviour directly and indirectly through complex mediation by multimodal empathy. The findings revealed the internal mechanism of autistic traits impeding prosocial behaviour and expanded our understandings of social behaviour in autism spectrum conditions (ASCs) and autistic traits in the general population. Furthermore, the results have implications for social adaptability interventions for individuals with ASCs and high levels of autistic traits.

Effects of Acute Alcohol Intoxication on Empathic Neural Responses for Pain.

The questions whether and how empathy for pain can be modulated by acute alcohol intoxication in the non-dependent population remain unanswered. To address these questions, a double-blind, placebo-controlled, within-subject study design was adopted in this study, in which healthy social drinkers were asked to complete a pain-judgment task using pictures depicting others' body parts in painful or non-painful situations during fMRI scanning, either under the influence of alcohol intoxication or placebo conditions. Empathic neural activity for pain was reduced by alcohol intoxication only in the dorsal anterior cingulate cortex (dACC). More interestingly, we observed that empathic neural activity for pain in the right anterior insula (rAI) was significantly correlated with trait empathy only after alcohol intoxication, along with impaired functional connectivity between the rAI and the fronto-parietal attention network. Our results reveal that alcohol intoxication not only inhibits empathic neural responses for pain but also leads to trait empathy inflation, possibly via impaired top-down attentional control. These findings help to explain the neural mechanism underlying alcohol-related social problems.

Motor, affective and cognitive empathy in adolescence: Interrelations between facial electromyography and self-reported trait and state measures.

This study examined interrelations of trait and state empathy in an adolescent sample. Self-reported affective trait empathy and cognitive trait empathy were assessed during a home visit. During a test session at the university, motor empathy (facial electromyography), and self-reported affective and cognitive state empathy were assessed in response to empathy-inducing film clips portraying happiness and sadness. Adolescents who responded with stronger motor empathy consistently reported higher affective state empathy. Adolescents' motor empathy was also positively related to cognitive state empathy, either directly or indirectly via affective state empathy. Whereas trait empathy was consistently, but modestly, related to state empathy with sadness, for state empathy with happiness few trait-state associations were found. Together, the findings provide support for the notion that empathy is a multi-faceted phenomenon. Motor, affective and cognitive empathy seem to be related processes, each playing a different role in the ability to understand and share others' feelings.

Influence of trait empathy on the emotion evoked by sad music and on the preference for it.

Some people experience pleasant emotion when listening to sad music. Therefore, they can enjoy listening to it. In the current study, we aimed to investigate such apparently paradoxical emotional mechanisms and focused on the influence of individuals' trait empathy, which has been reported to associate with emotional responses to sad music and a preference for it. Eighty-four elementary school children (42 males and 42 females, mean age 11.9 years) listened to two kinds of sad music and rated their emotional state and liking toward them. In addition, trait empathy was assessed using the Interpersonal Reactivity Index scale, which comprises four sub-components: Empathic Concern, Personal Distress, Perspective Taking, and Fantasy (FS). We conducted a path analysis and tested our proposed model that hypothesized that trait empathy and its sub-components would affect the preference for sad music directly or indirectly, mediated by the emotional response to the sad music. Our findings indicated that FS, a sub-component of trait empathy, was directly associated with liking sad music. Additionally, perspective taking ability, another sub-component of trait empathy, was correlated with the emotional response to sad music. Furthermore, the experience of pleasant emotions contributed to liking sad music.

Emotional face recognition, empathic trait (BEES), and cortical contribution in response to positive and negative cues. The effect of rTMS on dorsal medial prefrontal cortex.

The present study investigated the relationship between three different measures related to the affective empathy: facial expression detection in response to different emotional patterns (positive vs. negative), personal response to empathic scale [Balanced Emotional Empathy Scale (BEES)], and dorsal medial prefrontal cortex (dMPFC) contribution to mediate the facial detection task. Nineteen subjects took part in the study and they were required to recognize facial expression of emotions, after having empathized with these emotional cues. Repeated Transcranial Magnetic Stimulation (rTMS) method was used in the present research in order to produce a temporary virtual disruption of dMPFC activity. dMPFC disruption induced a worse performance, especially in response to negative expressions (i.e. anger and fear). High-BEES subjects paid a higher cost after frontal brain perturbation: they showed to be unable to correctly detect facial expressions more than low-BEES. Moreover, a "negative valence effect" was observed only for high-BEES, and it was probably related with their higher impairment to recognize negative more than positive expressions. dMPFC was found to support emotional facial expression recognition in an empathic condition, with a specific increased responsiveness for negative-valenced faces. The contribution of this research was discussed to explain the mechanisms underlying affective empathy based on rTMS application.