RESUMEN
Fourier ptychographic microscopy, as a computational imaging method, can reconstruct high-resolution images but suffers optical aberration, which affects its imaging quality. For this reason, this paper proposes a network model for simulating the forward imaging process in the Tensorflow framework using samples and coherent transfer functions as the input. The proposed model improves the introduced Wirtinger flow algorithm, retains the central idea, simplifies the calculation process, and optimizes the update through back propagation. In addition, Zernike polynomials are used to accurately estimate aberration. The simulation and experimental results show that this method can effectively improve the accuracy of aberration correction, maintain good correction performance under complex scenes, and reduce the influence of optical aberration on imaging quality.
RESUMEN
Empowered by pixel super-resolution (PSR) and phase retrieval techniques, lensless on-chip microscopy opens up new possibilities for high-throughput biomedical imaging. However, the current PSR phase retrieval approaches are time consuming in terms of both the measurement and reconstruction procedures. In this work, we present a novel computational framework for PSR phase retrieval to address these concerns. Specifically, a sparsity-promoting regularizer is introduced to enhance the well posedness of the nonconvex problem under limited measurements, and Nesterov's momentum is used to accelerate the iterations. The resulting algorithm, termed accelerated Wirtinger flow (AWF), achieves at least an order of magnitude faster rate of convergence and allows a twofold reduction in the measurement number while maintaining competitive reconstruction quality. Furthermore, we provide general guidance for step size selection based on theoretical analyses, facilitating simple implementation without the need for complicated parameter tuning. The proposed AWF algorithm is compatible with most of the existing lensless on-chip microscopes and could help achieve label-free rapid whole slide imaging of dynamic biological activities at subpixel resolution.
Asunto(s)
Algoritmos , Microscopía , Microscopía/métodosRESUMEN
Phaseless terahertz coded-aperture imaging (PL-TCAI) is a novel radar computational imaging method that utilizes the coded aperture and the incoherent detector array to achieve forward-looking and high-resolution imaging without relying on relative motion. In this paper, we propose a more reasonable and compact architecture for the PL-TCAI system and derive the imaging model of PL-TCAI based on the random frequency-hopping signal. Since most phase retrieval algorithms for PL-TCAI utilize only the intensity of echo signals to accurately reconstruct the target, excessive measurement samples are usually required. In order to reduce the number of measurement samples required for imaging, this paper proposes a sparse Wirtinger flow algorithm with optimal stepsize (SWFOS) by using the sparse prior of the target. The specific procedures of the SWFOS algorithm include the support recovery, initialization by truncated spectral method, iteration via gradient descent scheme, hard threshold operation, and stepsize optimization of iteration. Numerical simulations are performed, and the results show that the SWFOS algorithm not only has good performance for the PR problem, but can also sharply reduce the number of measurement samples required for imaging in the PL-TCAI system.