Integration- and separation-aware adversarial model for cerebrovascular segmentation from TOF-MRA.

PURPOSE: Cerebrovascular segmentation from time-of-flight magnetic resonance angiography (TOF-MRA) is important but challenging for the simulation and measurement of cerebrovascular diseases. Recently, deep learning has promoted the rapid development of cerebrovascular segmentation. However, model optimization relies on voxel or regional punishment and lacks global awareness and interpretation from the texture and edge. To overcome the limitations of the existing methods, we propose a new cerebrovascular segmentation method to obtain more refined structures. METHODS: In this paper, we propose a new adversarial model that achieves segmentation using segmentation model and filters the results using discriminator. Considering the sample imbalance in cerebrovascular imaging, we separated the TOF-MRA images and utilized high- and low-frequency images to enhance the texture and edge representation. The encoder weight sharing from the segmentation model not only saves the model parameters, but also strengthens the integration and separation correlation. Diversified discrimination enhances the robustness and regularization of the model. RESULTS: The adversarial model was tested using two cerebrovascular datasets. It scored 82.26% and 73.38%, respectively, ranking first on both datasets. The results show that our method not only outperforms the recent cerebrovascular segmentation model, but also surpasses the common adversarial models. CONCLUSION: Our adversarial model focuses on improving the extraction ability of the model on texture and edge, thereby achieving awareness of the global cerebrovascular topology. Therefore, we obtained an accurate and robust cerebrovascular segmentation. This framework has potential applications in many imaging fields, particularly in the application of sample imbalance. Our code is available at the website https://github.com/MontaEllis/ISA-model.

Pairwise attention-enhanced adversarial model for automatic bone segmentation in CT images.

Objective. Bone segmentation is a critical step in screw placement navigation. Although the deep learning methods have promoted the rapid development for bone segmentation, the local bone separation is still challenging due to irregular shapes and similar representational features.Approach. In this paper, we proposed the pairwise attention-enhanced adversarial model (Pair-SegAM) for automatic bone segmentation in computed tomography images, which includes the two parts of the segmentation model and discriminator. Considering that the distributions of the predictions from the segmentation model contains complicated semantics, we improve the discriminator to strengthen the awareness ability of the target region, improving the parsing of semantic information features. The Pair-SegAM has a pairwise structure, which uses two calculation mechanics to set up pairwise attention maps, then we utilize the semantic fusion to filter unstable regions. Therefore, the improved discriminator provides more refinement information to capture the bone outline, thus effectively enhancing the segmentation models for bone segmentation.Main results. To test the Pair-SegAM, we selected the two bone datasets for assessment. We evaluated our method against several bone segmentation models and latest adversarial models on the both datasets. The experimental results prove that our method not only exhibits superior bone segmentation performance, but also states effective generalization.Significance. Our method provides a more efficient segmentation of specific bones and has the potential to be extended to other semantic segmentation domains.

A deep adversarial model for segmentation-assisted COVID-19 diagnosis using CT images.

The outbreak of coronavirus disease 2019 (COVID-19) is spreading rapidly around the world, resulting in a global pandemic. Imaging techniques such as computed tomography (CT) play an essential role in the diagnosis and treatment of the disease since lung infection or pneumonia is a common complication. However, training a deep network to learn how to diagnose COVID-19 rapidly and accurately in CT images and segment the infected regions like a radiologist is challenging. Since the infectious area is difficult to distinguish manually annotation, the segmentation results are time-consuming. To tackle these problems, we propose an efficient method based on a deep adversarial network to segment the infection regions automatically. Then, the predicted segment results can assist the diagnostic network in identifying the COVID-19 samples from the CT images. On the other hand, a radiologist-like segmentation network provides detailed information of the infectious regions by separating areas of ground-glass, consolidation, and pleural effusion, respectively. Our method can accurately predict the COVID-19 infectious probability and provide lesion regions in CT images with limited training data. Additionally, we have established a public dataset for multitask learning. Extensive experiments on diagnosis and segmentation show superior performance over state-of-the-art methods.