Research on the Asymmetric Phenomenon of Voltage Polarity Based on Dielectric Wetting.

The present research investigated the voltage polarity asymmetry phenomenon based on dielectric wetting. In an ITO-hydrophobic layer-droplet setup, three reagents with different pH values (3.96, 7.0, and 10.18), two types of hydrophobic materials (AF1601 and 6%T6), and two different thicknesses (340 nm and 2.5 µm) of each material were systematically investigated. The results show that the thickness of the hydrophobic dielectric layer and the pH of the droplets had a significant impact on the droplet contact angle variation with the voltage. The contact angle on the thick hydrophobic dielectric layer followed the Lippmann-Young equation as the voltage changed. The angle of the thin hydrophobic dielectric layer was affected by its own properties and the type of droplet, which led to the occurrence of voltage polarity asymmetry of the electrowetting phenomenon. After further investigation of this phenomenon, it was found that it mainly accounted for the decrease in electric field strength at both ends of the droplet, which was caused by electrochemical reactions and changes in circuit resistance. The leakage current is an important indicator, and this phenomenon can be prevented by increasing the thickness of the hydrophobic dielectric layer.

Nonconductive Metal Oxide Gas Diffusion Layer for Mitigating Electrowetting during CO2 Electrolysis.

Gas diffusion electrodes (GDEs) are extensively used for high current density electrochemical CO2 electrolysis (ECO2R), enabled by significantly reducing mass transfer resistance of CO2 to the catalyst layer. Conventionally, these GDEs are based upon hydrophobic carbon-based gas-diffusion layers (GDLs) that facilitate the gas transport; however, these supports are prone to flood with electrolyte during electrolysis. This potential-induced flooding, known as electrowetting, is related to the inherent conductivity of carbon and limits the activity of ECO2R. To investigate the effect of electrical conductivity more carefully, a GDE is constructed based on a Cu mesh with a nonconductive microporous GDL applied to this substrate, the latter composed of a mixture of metal oxide and polytetrafluoroethylene. With alumina as the metal oxide, a stable operation is obtained at -200 mA cm-2 with 70% selectivity for ECO2R (with over half toward C2+ products) without flooding as observed by in situ microscopy. On the contrary, with a Vulcan carbon-based GDL, the initial activity is rapidly lost as severe flooding ensues. It is reasoned that electrowetting is averted by virtue of the nonconductive nature of alumina, providing a new perspective on alternative GDL compositions and their influence on ECO2R performance.

Trans-electrode pressure of gas-diffusion electrodes significantly influencing the electrochemical hydrogen peroxide production.

Hydrogen peroxide (H2O2) synthesis by electrochemical two-electron oxygen reduction has garnered increasing interest as a wide range of potential applications. Gas diffusion electrodes (GDEs) can effectively promote the H2O2 production efficiency by overcoming the oxygen mass transfer limitations but strongly influenced by the electrowetting process along the long-term operation. In this study, the effect of trans-electrode pressure (TEP) of GDE cathode on the electrowetting process was further elucidated. We controlled the TEP values of four types of GDEs: two Ni-based GDEs and two carbon cloth GDEs prepared by hot-pressing or brushing carbon black. SBA-15 was further used to regulate the microstructure of one Ni-based GDE. It was found that an optimal range of TEP occurred for all tested GDEs in terms of the max. concentration, the yield efficiency, the energy consumption, and the stability because TEP may change the triple-phase interface and influence the anti-electrowetting effect. The porosity of hot-pressed Ni GDE can maintain the TEP window and thus enhance the production of H2O2, likely via creating oxygen-containing functional groups and a bimodal pore structure on the electrode, revealed with several characterization techniques including SEM, CA, XPS, Raman spectra, CV and EIS. The porous Ni GDE presented an efficient and stable production of H2O2 for 10 cycles: yielding H2O2 at 4393.2-4602.2 mmol m-2 h-1 with current efficiencies of 94.2-98.7%. The best accumulated H2O2 concentration can reach up to 3.58 ωt% H2O2 at 10 h. The results provide an important reference for the industrial scaleup of electro-production of H2O2 with GDEs.

Orbital Electrowetting-on-Dielectric for Droplet Manipulation on Superhydrophobic Surfaces.

Electrowetting-on-dielectric (EWOD), recognized as the most successful electrical droplet actuation method, is essential in diverse applications, ranging from thermal management to microfluidics and water harvesting. Despite significant advances, it remains challenging to achieve repeatability, high speed, and simple circuitry in EWOD-based droplet manipulation on superhydrophobic surfaces. Moreover, its efficient operation typically requires electrode arrays and sophisticated circuit control. Here, a newly observed droplet manipulation phenomenon on superhydrophobic surfaces with orbital EWOD (OEW) is reported. Due to the asymmetric electrowetting force generated on the orbit, flexible and versatile droplet manipulation is facilitated with OEW. It is demonstrated that OEW droplet manipulation on superhydrophobic surfaces exhibits higher speed (up to 5 times faster), enhanced functionality (antigravity), and manipulation of diverse liquids (acid, base, salt, organic, e.g., methyl blue, artificial blood) without contamination, and good durability after 1000 tests. It is envisioned that this robust droplet manipulation strategy using OEW will provide a valuable platform for various processes involving droplets, spanning from microfluidic devices to controllable chemical reactions. The previously unreported droplet manipulation phenomenon and control strategy shown here can potentially upgrade EWOD-based microfluidics, antifogging, anti-icing, dust removal, and beyond.

Statistical Mechanics of Electrowetting.

We derive the ab initio equilibrium statistical mechanics of the gas-liquid-solid contact angle on planar periodic, monodisperse, textured surfaces subject to electrowetting. To that end, we extend an earlier theory that predicts the advance or recession of the contact line amount to distinct first-order phase transitions of the filling state in the ensemble of nearby surface cavities. Upon calculating the individual capacitance of a cavity subject to the influence of its near neighbors, we show how hysteresis, which is manifested by different advancing and receding contact angles, is affected by electrowetting. The analysis reveals nine distinct regimes characterizing contact angle behavior, three of which arise only when a voltage is applied to the conductive liquid drop. As the square voltage is progressively increased, the theory elucidates how the drop occasionally undergoes regime transitions triggering jumps in the contact angle, possibly changing its hysteresis, or saturating it at a value weakly dependent on further voltage growth. To illustrate these phenomena and validate the theory, we confront its predictions with four data sets. A benefit of the theory is that it forsakes trial and error when designing textured surfaces with specific contact angle behavior.

Multifunctional carbon nanotubes coated stainless steel mesh for electrowetting, hydrophobic, and dye absorption behavior.

Electrowetting behaviour for carbon nanotubes (CNT) grown on stainless steel mesh was investigated. The effect of temperature, time, and applied bias voltage on the contact angle of water droplets was studied. The impact of temperature variation on contact angle was also performed for the temperature ranging from 25 to 70 °C. A decrement of contact angle by 68% was observed for the mentioned range indicating a transition from a hydrophobic to hydrophilic nature. A similar trend was observed on the application of electric potential to the CNT-modified stainless-steel mesh ranging from 0 to 8 V with a transition of contact angle from 146 to 30 deg respectively. A comparative analysis for the contact angle variation with time for CNT-coated mesh and uncoated mesh was performed for 180 min. It is observed that uncoated mesh shows a reduction in contact angle to 0 deg with time while the CNT coated mesh shows surplus hydrophobicity with a 2 deg decrement in the extent of time. CNT-modified mesh successfully absorbs 95% of rhodamine B (RB) dye and detergent from water in 10 cycles.

Self-Powered Colorful Dynamic Electrowetting Display Systems Based on Triboelectricity.

Electrowetting displays (EWDs) based on microfluidics are highly sought after in the fields of electronic devices, smart homes, and information communication. However, the power supply of the EWD systems for visually engaging multi-color displays remains a big challenge. Herein, self-powered colorful dynamic display systems are developed by integrating the triboelectric nanogenerator (TENG) with the EWD device. The TENG is designed with a nanotube-patterned surface and can generate open-circuit voltages ranging from 30 to 295 V by controlling the contact area. The wetting property of the micro-droplet exhibits a response to the applied voltage, enabling the triboelectricity-triggered electrowetting-on-dielectric. Driven by the voltage of 160 V, the monochromatic EWD exhibits bright color switching from magenta to transparent with a pixel aperture ratio of 78%, and the recovery process can be rapidly completed. Furthermore, the self-powered colorful dynamic EWD system can be achieved. By selectively applying the voltage to the pixels in the three monochromatic layers that constitute the colorful EWD, the wetting properties of the fluids can be controlled, allowing for colorful dynamic display. This work contributes to the advancement of color display technology for portable and wearable electronic ink displays, indoor and outdoor sports equipment, and information communication.

Inkjet-Printed Dielectric Layer for the Enhancement of Electrowetting Display Devices.

Electrowetting with a dielectric layer is commonly preferred in practical applications. However, its potential is often limited by factors like the properties of the dielectric layer and its breakdown, along with the complexity of the deposition method. Fortunately, advancements in 3D inkjet printing offer a more adaptable solution for making patterned functional layers. In this study, we used a negative photoresist (HN-1901) to create a new dielectric layer for an electrowetting display on a 3-inch ITO glass using a Dimatix DMP-2580 inkjet printer. The resulting devices performed better due to their enhanced resistance to dielectric breakdown. We meticulously investigated the physical properties of the photoresist material and printer settings to achieve optimal printing. We also controlled the uniformity of the dielectric layer by adjusting ink drop spacing. Compared to traditional electrowetting display devices, those with inkjet-printed dielectric layers showed significantly fewer defects like bubbles and electrode corrosion. They maintained an outstanding response time and breakdown resistance, operating at an open voltage of 20 V. Remarkably, these devices achieved faster response times of ton 22.3 ms and toff 14.2 ms, surpassing the performance of the standard device.

Transitional Electrodes in Electrowetting-Based Droplet Dispensing.

Digital microfluidic systems based on electrowetting-on-dielectric technology, particularly valuable in producing and manipulating microdroplets steadily and consistently, have experienced notable advancements in recent years. In this paper, experimental characterizations reveal that simply adding one transitional electrode between the reservoir and the splitting electrode improves the volumetric consistency and reproducibility for droplet dispensing. The volumetric coefficient variation of the consecutively dispensed droplets from a non-refilling reservoir decreases by 1% after the addition of one transitional electrode, with no extra external apparatus. This work provides a straightforward yet effective approach to the improvement of digital microfluidic systems and micro total analysis systems.

Switchable Optical Properties of Dyes and Nanoparticles in Electrowetting Devices.

The optical properties of light-absorbing materials in optical shutter devices are critical to the use of such platforms for optical applications. We demonstrate switchable optical properties of dyes and nanoparticles in liquid-based electrowetting-on-dielectric (EWOD) devices. Our work uses narrow-band-absorbing dyes and nanoparticles, which are appealing for spectral-filtering applications targeting specific wavelengths while maintaining device transparency at other wavelengths. Low-voltage actuation of boron dipyromethene (BODIPY) dyes and nanoparticles (Ag and CdSe) was demonstrated without degradation of the light-absorbing materials. Three BODIPY dyes were used, namely Abs 503 nm, 535 nm and 560 nm for dye 1 (BODIPY-core), 2 (I2BODIPY) and 3 (BODIPY-TMS), respectively. Reversible and low-voltage (≤20 V) switching of dye optical properties was observed as a function of device pixel dimensions (300 × 900, 200 × 600 and 150 × 450 µm). Low-voltage and reversible switching was also demonstrated for plasmonic and semiconductor nanoparticles, such as CdSe nanotetrapods (abs 508 nm), CdSe nanoplatelets (Abs 461 and 432 nm) and Ag nanoparticles (Abs 430 nm). Nanoparticle-based devices showed minimal hysteresis as well as faster relaxation times. The study presented can thus be extended to a variety of nanomaterials and dyes having the desired optical properties.

High-Performance Multi-Level Grayscale Conversion by Driving Waveform Optimization in Electrowetting Displays.

As a new type of reflective display, electrowetting display (EWD) has excellent dynamic display performance, which is based on polymer coatings. However, there are still some issues which can limit its performance, such as oil backflow and the hysteresis effect which reduces the stability and response speed of EWDs. Therefore, an effective driving waveform was proposed to overcome these drawbacks, which consisted of grayscale conversions between low gray levels and high gray levels. In the driving waveform, to stabilize the EWD at any initial grayscale (low gray levels/high gray levels), an exponential function waveform and an AC signal were used. Then, the grayscale conversion was performed by using an AC signal with a switching voltage to quickly achieve the target grayscale. Finally, another AC signal was used to stabilize the EWD at the target grayscale. A set of driving waveforms in grayscale ranging across four levels was designed using this method. According to the experimental results, oil backflow and the hysteresis effect could be effectively attenuated by the proposed driving waveforms. During conversion, the response speed of EWDs was boosted by at least 9.37% compared to traditional driving waveforms.

Electric-Field-Induced Selective Directed Transport of Diverse Droplets.

Droplet directional transport is one of the central topics in microfluidics and lab-on-a-chip applications. Selective transport of diverse droplets, particularly in another liquid phase environment with controlled directions, is still challenging. In this work, we propose an electric-field gradient-driven droplet directional transport platform facilitated by a robust lubricant surface. On the platform, we clearly demonstrated a liquid-inherent critical frequency-dominated selective transport of diverse droplets and a driving mechanism transition from electrowetting to liquid dielectrophoresis. Enlightened by the Kelvin-Helmholtz theory, we first realize the directional droplet transport in another liquid phase whenever a permittivity difference exists. Co-transport of multiple droplets and various combinations of droplet types, as well as multifunctional droplet transport modes, are realized based on the presented powerful electric-field gradient-driven platform, overcoming the limitations of the surrounding environment, liquid conductivity, and intrinsic solid-liquid wetting property existing in traditional droplet transport strategies. This work may inspire new applications in liquid separation, multiphase microfluidic manipulation, chemical reagent selection, and so on.

Deformation of confined liquid interfaces by inhomogeneous electric fields and localized particle forces.

HYPOTHESIS: Oil-water interfaces that are created by confining a certain amount of oil in a square shaped pixel (∼200 x 200 µm2 with a height of ∼10 µm) topped by a layer of water, have a curvature that depends on the amount of oil that happens to be present in the confining area. Under the application of an electric field normal to the interface, the interface will deform due to inhomogeneities in the electric field. These inhomogeneities are expected to arise from the initial curvature of the meniscus, from fringe fields that emerge at the confining pixel walls and, if applicable, from interfacially adsorbed particles. MODELING AND EXPERIMENTS: We model the shape of the confined oil-water interface invoking capillarity and electrostatics. Furthermore, we measure the initial curvature by tracking the position of interfacially adsorbed particles depending on sample tilt. FINDINGS: We found that the pixels exhibited meniscus curvature radii ranging from 0.6-7 mm. The corresponding model based minimum oil film thicknesses range between 0.7 and 9 µm. Furthermore, the model shows that the initial meniscus curvature can increase up to 76 percent relative to the initial curvature by the electric field before the oil film becomes unstable. The pixel wall and particles are shown to have minimal impact on the interface deformation.

Simulation of Electrowetting-Induced Droplet Detachment: A Study of Droplet Oscillations on Solid Surfaces.

The electrowetting-induced detachment of droplets from solid surfaces is important for numerous applications in the fields of heat transfer and fluid mechanics. The forced oscillations of droplets on solid surfaces and their ability to detach are studied. In this study, the process is efficiently simulated by implementing a powerful methodology developed by our team. Our results agree with experiments showing that optimal detachment, in terms of actuation energy, is achieved when the application of voltage is synchronized with the spreading time of the droplet. Under these conditions, the droplet oscillates with a period close to that of a mirrored Rayleigh droplet. The relationship between the droplet's oscillation period and its physical properties is examined. During voltage-droplet synchronization, the droplet's ability to detach depends mostly on its contact angle, its viscosity, and the applied voltage. An energy analysis is also conducted, revealing how energy is supplied to the droplet by electrowetting-induced detachment.

Research on Hydrodynamic Characteristics of Electronic Paper Pixels Based on Electrowetting.

In this paper, we propose a driving waveform with a complex ramp pulse for an electrowetting display system. The relationship between the contact angle and viscosity of inks was calculated based on the fluid-motion characteristics of different viscosities. We obtained the suitable range of viscosity and voltage in the liquid-oil-solid three-phase contact display system. We carried out model simulation and driving waveform design. The result shows that the driving waveform improves the response speed and aperture ratio of electrowetting. The aperture ratio of electrowetting pixels is increased to 68.69%. This research is of great significance to optimizing the structure of fluid material and the design of driving waveforms in electrowetting displays.

Sub-5-Minute Ultrafast PCR using Digital Microfluidics.

The development of a rapid and reliable polymerase chain reaction (PCR) method for point-of-care (POC) diagnosis is crucial for the timely identification of pathogens. Microfluidics, which involves the manipulation of small volumes of fluidic samples, has been shown to be an ideal approach for POC analysis. Among the various microfluidic platforms available, digital microfluidics (DMF) offers high degree of configurability in manipulating µL/nL-scale liquid and achieving automation. However, the successful implementation of ultrafast PCR on DMF platforms presents challenges due to inherent system instability. In this study, we developed a robust and ultrafast PCR in 3.7-5 min with a detection sensitivity comparable to conventional PCR. Specifically, the implementation of the pincer heating scheme homogenises the temperature within a drop. The utilization of a µm-scale porous hydrophobic membrane suppresses the formation of bubbles under high temperatures. The design of a groove around the high-temperature zone effectively mitigates the temperature interference. The integration of a soluble sensor into the droplets provides an accurate and instant in-drop temperature sensing. We envision that the fast, robust, sensitive, and automatic DMF system will empower the POC testing for infectious diseases.

Development of Cyclic Tetrasiloxane Polymer as a High-Performance Dielectric and Hydrophobic Layer for Electrowetting Displays.

Cyclic tetrasiloxane polymer (CTP) has recently garnered interest as a hydrophobic material with unique properties. This study aims to enhance the dielectric constant of CTP films by introducing excess Si-H groups and to explore the impact of synthesis and processing conditions on the resulting properties. The film demonstrates high hydrophobicity, with contact angles of 107° in air and 165° in n-decane, along with a notable dielectric constant of 5.1°. Furthermore, the CTP film displays reversible electrowetting behavior with low contact angle hysteresis (2°) and possesses good transparency (∼99%) and thermal stability. As such, the CTP film has significant potential as a material for the electric wetting of hydrophobic dielectric layers and may serve as a promising alternative in electrowetting applications.

Digital Microfluidic Multiplex RT-qPCR for SARS-CoV-2 Detection and Variants Discrimination.

Continuous mutations have occurred in the genome of the SARS-CoV-2 virus since the onset of the COVID-19 pandemic. The increased transmissibility of the mutated viruses has not only imposed medical burdens but also prolonged the duration of the pandemic. A point-of-care (POC) platform that provides multitarget detection will help to track and reduce disease transmissions. Here we detected and discriminated three genotypes of SARS-CoV-2, including the wildtype and two variants of concern (VOCs), the Delta variant and Omicron variant, through reverse transcription quantitative polymerase chain reaction (RT-qPCR) on a digital microfluidics (DMF)-based cartridge. Upon evaluating with the RNA samples of Omicron variant, the DMF RT-qPCR presented a sensitivity of 10 copies/µL and an amplification efficiency of 96.1%, capable for clinical diagnosis. When spiking with SARS-CoV-2 RNA (wildtype, Delta variant, or Omicron variant) and 18S rDNA, the clinical analog samples demonstrated accurate detection and discrimination of different SARS-CoV-2 strains in 49 min.

Electrowetting-driven liquid lens for ultrasound: Enabling controllable focal length and flexible beam steering.

Focused ultrasound is an increasingly popular non-invasive treatment modality. Still, its fixed focal point requires an array ultrasound transducer or scanning system to cover different therapeutic scenarios. To address this limitation, we developed an electrically-controlled liquid lens that enables dynamic beam focusing and steering of the incident plane ultrasound beam. The lens was carefully optimized for low-energy attenuation and low-voltage driving. We evaluated the performance of the lens using a homemade 5.5-MHz planar transducer with a 7.5-mm aperture. Our results demonstrate that the planar ultrasound beam can be adjusted to a focused beam with a focal length from 27 mm to 32 mm within 1 s by increasing the electric input (0-60 V) to the lens. Additionally, the beam angle of the ultrasound is tunable from -5 to 5° by adjusting the charge distribution on the lens. Our design enables real-time, fast-response, on-demand changing of focal length and beam angle for a single-element planar transducer. Our study presents a promising technology for altering the ultrasound beam of a planar single-element transducer for different ultrasound applications. The development of this electrically-controlled liquid lens has the potential to enhance the efficacy of focused ultrasound treatment and improve patient outcomes.

Stability Study of Multi-Level Grayscales Based on Driving Waveforms for Electrowetting Displays.

Electrowetting Display (EWD) is a new reflective display with an outstanding performance of color video playback. However, some problems still exist and affect its performance. For instance, oil backflow, oil splitting, and charge trapping phenomena may occur during the driving process of EWDs, which would decrease its stability of multi-level grayscales. Therefore, an efficient driving waveform was proposed to solve these disadvantages. It consisted of a driving stage and a stabilizing stage. First, an exponential function waveform was used in the driving stage for driving the EWDs quickly. Then, an alternating current (AC) pulse signal waveform was used in the stabilizing stage to release the trapped positive charges of the insulating layer to improve display stability. A set of four level grayscale driving waveforms were designed by using the proposed method, and it was used in comparative experiments. The experiments showed that the proposed driving waveform could mitigate oil backflow and splitting effects. Compared to a traditional driving waveform, the luminance stability was increased by 8.9%, 5.9%, 10.9%, and 11.6% for the four level grayscales after 12 s, respectively.