RESUMEN
Seagrass is an important marine habitat that provides benefits to society in the form of ecosystem services. Services include the provision of food via fisheries, the regulation of water quality and the ability to sequester and store carbon. In the UK, seagrass beds are in decline, increasing the risk of ecosystem service loss. Current efforts to protect, restore and create seagrass habitat, beyond spatial management measures, rely on grant funding and donations. Emerging carbon, biodiversity and wider ecosystem service markets offering potential revenue sources could facilitate the enhancement of seagrass habitat at scale. Participation in ecosystem service markets, requires that projects deliver on the ecosystem service benefits defined. As the benefits will have been paid for, there are risks associated with not delivering on ecosystem service benefits. It is important that the risk is clearly defined. In this study we further the marine natural capital and risk register approach and apply the method to a case study area to support the development of sustainable funding options for seagrass habitat enhancement in Plymouth Sound, UK. Habitat Suitability modelling is also used to map potential areas for seagrass habitat enhancement. We find that, in the Plymouth Sound area, the risk of loss of ecosystem services for subtidal seagrass habitats is, at present, high. This is primarily linked to the declining extent and condition of subtidal seagrass assets. Under current governance, all of Plymouth Sound's subtidal seagrass are within a Marine Protected Area, though this conservation designation does not guarantee that the seagrass bed is protected from damaging activity. Under current environmental conditions there is opportunity for widespread seagrass restoration and creation. Risk to seagrass beds and any future private funding could be reduced by governance actions that enable effective direct protection of the seagrass assets and mitigate harmful pressures (e.g., reduction of water pollution). Emerging financial 'products' from seagrass ecosystem services that can support restoration and creation, require a high degree of integrity. The natural capital asset and risk register framework can provide information to underpin product development. With the development of revenue streams from ecosystem services there is a need for more intentional governance and site-based monitoring of these habitats as natural capital assets. Further research is needed to define any social or economic outcomes. Synthesis and Application: By assessing the risk to the status of seagrass assets through this approach, it is possible to determine the complementary governance actions needed to underpin investment in seagrass habitat enhancement. The methods are transferable to other locations where data exists to define the asset status. These specific findings are relevant nationally where similar vectors of risk (pressures) are identified.
Asunto(s)
Conservación de los Recursos Naturales , Ecosistema , Conservación de los Recursos Naturales/economía , Reino Unido , BiodiversidadRESUMEN
This study aims to explore the meaning of participating in nature-based activities as seen from the perspective of people living with dementia. Being in a natural environment in contrast to a constructed environment has not previously been investigated, even though several studies have shown that nature-based activities may impact people's well-being, feelings of happiness, and a feeling of maintaining selfhood. A qualitative design was applied in this study, using walking-interviews to explore the meaning of participating in nature-based activities. Interviews have been conducted with 15 people with mild to moderate dementia in three municipalities. The analytical process using reflexive thematic analysis resulted in an overall theme that participation in nature-based activity nourishes the person by creating a feeling of having value as a person. Further, three subthemes were identified: Oasis for being, linking to the past, present, and future, and feeling capable. The findings of this study indicate that sensory stimulation when being in nature promotes embodied narratives and experiences, which contributes to the feeling of connecting to oneself, and to feeling valuable as a capable human being. This provides an important implication for practice that accessible nature-based activities may provide an overlooked opportunity to support self-identity for people living with dementia. However, it is time for a cultural and discursive shift in nature-based activities, where a delicate balance ensures that people living with dementia can derive inherent value from simply being in nature.
RESUMEN
BACKGROUND: Loneliness is common among older adults in institutional settings. It leads to adverse effects on health and wellbeing, for which nature contact with peers in turn may have positive impact. However, the effects of nature engagement among older adults have not been studied in randomised controlled trials (RCT). The "Friends in Nature" (FIN) group intervention RCT for lonely older adults in Helsinki assisted living facilities (ALFs) aims to explore the effects of peer-related nature experiences on loneliness and health-related quality of life (HRQoL). In this study we aim describe the participants' baseline characteristics of the RCT, feasibility of FIN intervention and intervention participants' feedback on the FIN. METHODS: Lonely participants were recruited from 22 ALFs in Helsinki area, Finland, and randomised into two groups: 1) nature-based social intervention once a week for nine weeks (n = 162) and 2) usual care (n = 157). Demographics, diagnoses and medication use were retrieved from medical records, and baseline cognition, functioning, HRQoL, loneliness and psychological wellbeing were assessed. Primary trial outcomes will be participants' loneliness (De Jong Giervald Loneliness Scale) and HRQoL (15D). RESULTS: The mean age of participants was 83 years, 73% were female and mean Minimental State Examination of 21 points. The participants were living with multiple co-morbidities and/or disabilities. The intervention and control groups were comparable at baseline. The adherence with intervention was moderate, with a mean attendance of 6.8 out of the nine sessions. Of the participants, 14% refused, fell ill or were deceased, and therefore, participated three sessions or less. General subjective alleviation of loneliness was achieved in 57% of the intervention participants. Of the respondents, 96% would have recommended a respective group intervention to other older adults. Intervention participants appreciated their nature excursions and experiences. CONCLUSIONS: We have successfully randomised 319 lonely residents in assisted living facilities into a trial about the effects of nature experiences in a group-format. The feedback from participants was favourable. The trial will provide important information about possibilities of alleviating loneliness with peer-related nature-based experiences in frail residents. TRIAL REGISTRATION: ClinicalTrials.gov, ID: NCT05507684. Registration 19/08/2022.
Asunto(s)
Instituciones de Vida Asistida , Soledad , Calidad de Vida , Humanos , Soledad/psicología , Femenino , Masculino , Finlandia/epidemiología , Anciano , Anciano de 80 o más Años , Calidad de Vida/psicología , Intervención Psicosocial/métodosRESUMEN
Building-Integrated Greenery systems, i.e., green roofs, walls, and facades, are Nature-based Solutions that make possible the renaturing of cities when there is no room for traditional greenery solutions. These green systems provide several ecosystem services at both the building and city level, such as urban heat island effect mitigation and noise reduction, support for biodiversity, runoff control, thermal and acoustic insulation, etc. However, once implemented in real cases, their impact is almost never evaluated. This fact limits the possibility of carrying out cost-benefit analyses that contribute to justifying their long-term maintenance, thus putting at risk their long-term sustainability and consequently the provision of benefits. Unlike existing approaches, the method presented here offers a comprehensive and practical tool that addresses the gap in BIG systems' impact evaluation, facilitating informed decision-making and promoting the long-term sustainability of BIG systems.â¢In its design, the current references at European and global level for building-integrated systems impact assessment has been considered.â¢It is easily replicable in any real project and enables the collaboration of involved stakeholders.â¢The method is unprecedented and allows a holistic assessment of the impact of BIG in real cases, in terms of ecosystem services provided.
RESUMEN
In wastewater treatment, two issues have recently received increased attention: nature-based solutions for addressing urban water stress through decentralized treatment and re-use; and emerging pollutants such as microplastics (MPs). At the interface of these, this study investigated living green walls for greywater treatment and their potential for MP removal. A large, pilot-scale green wall was irrigated with greywater (a mix of water collected from laundry, dishwasher, bathroom sinks, and synthetic greywater), and effluent from planted and unplanted sections was compared. MPs >50 µm were analyzed using µRaman spectroscopy and supplementary fluorescence microscopy imaging. The green wall proved efficient for the reduction of chemical oxygen demand (COD) (around 80%), removal of total suspended solids (TSS) (around 90%) and MPs, especially for MPs of the non-polar, hydrophobic polymer type polystyrene and MPs sized 100-500 µm. MP removal was improved in the planted (50-60%) compared to the unplanted section (20%), especially for the size fraction 100-500 µm. Physical filtration by the green wall growing media (a mix of perlite with a grain size of 1-5 mm, and coconut fiber), which was further enhanced by plant roots decreasing the effective pore size, can be considered the most important removal mechanism. Charge-mediated adsorption cannot be expected as MPs and growing media mix were both negatively charged at the prevailing water pH (7-8). Fluorescence imaging for MP analysis, using a merged UV/blue light fluorograph, overestimated MP concentrations in greywater (hundreds of MPs per sample were identified by fluorescence imaging versus tens of MPs by µRaman spectroscopy) and would benefit from further improvement before it can be reliably applied as a cheaper and faster alternative methodology for MP analysis.
RESUMEN
Many believe that enhanced geothermal systems (EGS) can greatly increase the extraction of geothermal energy worldwide, helping to decarbonize heat and electricity production. Effective communication is key to realizing the potential of EGS, yet we currently know little about how the public perceives this emerging technology. This exploratory study contributes to the literature with a cross-national survey in the United States (n = 1003) and Switzerland (n = 1028), two countries with active EGS projects. Specifically, we explore how EGS support relates to beliefs about the deep underground and perceptions of EGS as tampering with nature. The results show that respondents tend to perceive the deep underground as part of nature, dangerous, and unpredictable. The majority are positive about using the deep underground as a resource, although there were variations regarding specific underground activities. In both countries, EGS support is greater for respondents who perceive the underground as something for human use, perceive more benefits than risks from EGS, and support their country's transition to renewable energy. In Switzerland, EGS support is positively related to trust in industry developers and negatively related to perceptions that EGS is tampering with nature. The results offer novel theoretical insights into perceptions of the deep underground in relation to energy development. From a practical standpoint, the results suggest that those seeking to develop EGS may want to consider how to familiarize individuals with current subsurface energy activities, including efforts to protect the underground from unwanted consequences of "tampering," alongside engaging in discussions about the risks and benefits of EGS.
RESUMEN
Human population growth constantly requires an increase in the production of food and products from the timber industry. To meet this demand, agriculture and planted forests are advancing over natural areas. In view of this, it is necessary to know the effects of land use for different purposes (grain production, pastures, planted forests, fruit production and among other uses) on the genetic diversity of populations of native species. This knowledge can assist in land use planning as well as in the development of conservation strategies for native species. In this study, we evaluated the effect of land use for agriculture (mainly for cereal production) and planted forests on the genetic diversity of Baccharis crispa Spreng., a herb native to South America. To achieve our goals, we compared population genetic data obtained with three molecular markers (microsatellites, inter-simple sequence repeat and isoenzymes) with data on land use for agriculture and planted forests from 15 different locations. Our results showed that regardless of the molecular marker used, the greater the use of land for agriculture and planted forests, the lower was the genetic diversity of B. crispa populations. Baccharis crispa is a semi-perennial species that needs at least one year to reach its reproductive period, which is prevented in agricultural areas due to the land being turned over or dissected with herbicides every 6 months. In the studied regions, the planted forests are of eucalypt and/or pine, which besides being species with a high production of allelopathic substances, produce strong shading and B. crispa is a species that inhabits open grassland that needs a high incidence of sunlight for development. The data obtained in our study can assist in the decision-making to use land in order to reconcile the production of supplies for humanity and for the conservation of nature.
RESUMEN
Aboveground and belowground attributes of terrestrial ecosystems interact to shape carbon (C) cycling. However, plants and soil organisms are usually studied separately, leading to a knowledge gap regarding their coordinated contributions to ecosystem C cycling. We explored whether integrated consideration of plant and nematode traits better explained soil organic C (SOC) dynamics than plant or nematode traits considered separately. Our study system was a space-for-time natural restoration chronosequence following agricultural abandonment in a subtropical region, with pioneer, early, mid and climax stages. We identified an integrated fast-slow trait spectrum encompassing plants and nematodes, demonstrating coordinated shifts from fast strategies in the pioneer stage to slow strategies in the climax stage, corresponding to enhanced SOC dynamics. Joint consideration of plant and nematode traits explained more variation in SOC than by either group alone. Structural equation modeling revealed that the integrated fast-slow trait spectrum influenced SOC through its regulation of microbial traits, including microbial C use efficiency and microbial biomass. Our findings confirm the pivotal role of plant-nematode trait coordination in modulating ecosystem C cycling and highlight the value of incorporating belowground traits into biogeochemical cycling under global change scenarios.
RESUMEN
The Human Footprint (HFP) and Habitat Quality (HQ) are critical factors influencing the species' distribution, yet their relation to biodiversity, particularly in mountainous regions, still remains inadequately understood. This study aims to identify the primary factor that affects the biodiversity by comparing the impact of the HFP and HQ on the species' richness of Cetartiodactyla in the Kunlun-Pamir Plateau and four protected areas: The Pamir Plateau Wetland Nature Reserve, Taxkorgan Wildlife Nature Reserve, Middle Kunlun Nature Reserve and Arjinshan Nature Reserve through multi-source satellite remote sensing product data. By integrating satellite data with the Integrated Valuation of Ecosystem Services and Trade-offs (InVEST)HQ model and utilizing residual and linear regression analysis, we found that: (1) The Wildness Area (WA) predominantly underwent a transition to a Highly Modified Area (HMA) and Intact Area (IA), with a notable 12.02% rise in stable regions, while 58.51% rather experienced a negligible decrease. (2) From 1985 to 2020, the Kunlun-Pamir Plateau has seen increases in the forestland, water, cropland and shrubland, alongside declines in bare land and grassland, denoting considerable land cover changes. (3) The HQ degradation was significant, with 79.81% of the area showing degradation compared to a 10.65% improvement, varying across the nature reserves. (4) The species richness of Cetartiodactyla was better explained by HQ than by HFP on the Kunlun-Pamir Plateau (52.99% vs. 47.01%), as well as in the Arjinshan Nature Reserve (81.57%) and Middle Kunlun Nature Reserve (56.41%). In contrast, HFP was more explanatory in the Pamir Plateau Wetland Nature Reserve (88.89%) and the Taxkorgan Wildlife Nature Reserve (54.55%). Prioritizing the restoration of degraded habitats areas of the Kunlun Pamir Plateau could enhance Cetartiodactyla species richness. These findings provide valuable insights for the biodiversity management and conservation strategies in the mountainous regions.
RESUMEN
Recognition of the health benefits of nature contact has increased. Simultaneously, growing numbers of people worldwide experience loneliness. There is a movement towards prescribing nature-based activities to improve/promote social connections, health, and quality of life. Yet, what constitutes a therapeutic nature dose is not well understood, due in part, to the lack of instruments that capture the characteristics of nature-based activities and measure 'nature dose.' We created a nature dose measurement tool to fill this gap by capturing various aspects of contact with nature and perceptions regarding park access, quality, naturalness, psychological distance to nature, and biodiversity. This tool will facilitate greater understanding of how natural areas, nature-based activities, and nature exposure reduce loneliness and promote health-related quality of life. Measuring nature dose with standardized tools and documenting benefits will generate the evidence base needed to design, implement and evaluate nature-based social interventions for improving health and quality of life.â¢This tool captures the nature dose to reduce loneliness and promote quality of life.â¢Constructs range from park quality and access, to mood, to biodiversity perceptions.â¢The standardized nature dose tool will help design nature-based social interventions.
RESUMEN
The growing environmental risks induced by interacting climate and human-induced pressures threaten the survival and growth of marine coastal ecosystems (MCEs) and the ecosystem services they provide. Nature-based solutions (NBS), consisting of ecosystem-based approaches, have emerged as vital tools for climate adaptation and mitigation facing biodiversity loss and societal challenges. Identifying suitable environmental conditions for implementing Blue-NBS in marine coastal areas is a key priority to drive robust and cost-effective nature-based adaptation pathways. This study developed a suitability model for Blue-NBS, with a specific focus on Posidonia oceanica meadows in the Mediterranean Sea under a baseline scenario. GIS-based Multiple Criteria Decision Analysis (MCDA) was applied for data integration and prioritization of different environmental variables in geomorphological (e.g., depth), water quality (WQ) (e.g., salinity), and climatic (e.g., thermal stress) sub-groups. Suitability classes and scores for each variable were determined using statistical distributions, ensuring a data-driven approach to defining environmental suitability. Variables' weights were derived from the Analytic Hierarchy Process (AHP) based on expert judgment and then combined with scores to generate suitability maps for managing Blue-NBS on seagrasses. Depth was found to be the most dominant environmental variable, with shallow areas (e.g., Northern Adriatic, Gulf of Gabés) showing higher suitability. The southern part of the Mediterranean (e.g., Egypt) reported relatively low scores for both climate and WQ, while the Northern Adriatic had the lowest WQ scores. This study represents the first attempt to evaluate Blue-NBS suitability for seagrass meadows at the eco-regional scale with geomorphologic, WQ, and climatic variables, providing decision support for the selection and allocation of Blue-NBS in different environmental settings. The resulting environmental suitability maps represent a basis for the integration of socio-economic and governance-related indicators into a more complex, multi-tier approach to support NBS mainstreaming.
RESUMEN
Microplastics pose detrimental effects on the environment, aquatic products, and human health. This comprehensive analysis highlights the repercussions of microplastic contamination within aquaculture. Microplastics in aquaculture are primarily from land-based plastic waste, tourism-related disposal, shipping activities, fisheries/aquaculture, and atmospheric deposition. In aquaculture environments, microplastics have the potential to discharge harmful additives, attract pollutants, degrade the aquaculture setting, and induce toxicological effects. These particles pose ecological risks and can impact human health. Assessing the destiny of microplastics in aquaculture ecosystems is crucial to determining the role of aquaculture in contributing to microplastic contamination within the watershed. It particularly emphasizes the ecological consequences for aquaculture species and the subsequent health threats for humans. The review strongly supports strict regulations to control and limit microplastic presence within aquaculture ecosystems. Clear regulations are essential for reducing microplastics in aquaculture, thereby ensuring food safety. A novel nature-based solution is proposed using methods like microplastic biofilters, biodegradation, and wetlands. These innovations can be conducted in aquatic ecosystems to serve as microplastic biofilters, effectively eliminating waterborne microplastics. In the future, however, it is crucial to develop additional emergency treatment measures to avoid the potential negative impacts of microplastics on both aquaculture and human health.
RESUMEN
Climate change impacts comprise a particular challenge for authorities when reconciling the implications of land use planning decisions. Whilst Strategic Environmental Assessment (SEA) is typically applied to the development of urban land use plans, the selection of mitigation and adaptation strategies for climate change impacts can have knock-on effects on nature. However, Nature-based Solutions (NbSs) could provide an innovative means of addressing climate change mitigation and adaptation without these knock-on effects. The main aim of this research is therefore to propose a conceptual framework for embedding NbSs into the main stages of the SEA process to potentially enhance climate change mitigation and adaptation in urban land use planning. This is achieved through a systematic literature review of academic and grey literature sources, with subsequent content analysis. This study demonstrates the value of matching these manifold NbS approaches to climate change impacts potentially addressed in SEA process stages and suggests how this might be achieved in practice focusing on urban land use plans.
RESUMEN
Climate change can exacerbate pest population growth, posing significant threats to ecosystem functions and services, social development, and food security. Risk assessment is a valuable tool for effective pest management that identifies potential pest expansion and ecosystem dispersal patterns. We applied a habitat suitability model coupled with priority protection planning software to determine key monitoring areas (KMA) for tree insect pest risks under climate change and used forest ecoregions and nature reserves to assess the ecological risk of insect pest invasion. Finally, we collated the prevention and control measures for reducing future pest invasions. The KMA for tree insect pests in our current and future climate is mainly concentrated in eastern and southern China. However, with climate change, the KMA gradually expands from southeastern to northeastern China. In the current and future climate scenarios, ecoregions requiring high monitoring levels were restricted to the eastern and southern coastal areas of China, and nature reserves requiring the highest monitoring levels were mainly distributed in southeastern China. Tree insect pest invasion assessment using ecoregions and nature reserves identified that future climates increase the risk of pest invasions in forest ecoregions and nature reserves, especially in northeastern China. The increased risk and severity of tree insect pest invasions require implementing monitoring and preventative measures in these areas. We effectively assessed the pest invasion risks using forest ecoregions and nature reserves under climate change. Our assessments suggest that monitoring and early prevention should focus on southeastern and northeastern China.
RESUMEN
BACKGROUND: Mental health disease constitutes 25% of the total burden of disease in Denmark. In the last few years, an increasing tendency for seeking the ocean has arisen, and winter bathing is one of the outdoor activities with a large rise in popularity. OBJECTIVES: The purpose of this study was to explore if and how regular winter bathing in blue spaces can affect people's mental health. METHODS: This study employed a qualitative design using fieldwork with semi-structured interviews with four members from three different winter bathing clubs. The empirical data were thematically analyzed followed by theoretical analysis. RESULTS: The results revealed five themes: Social Connectedness; Blue Nature as a Free Space; The Motivation Behind Winter Bathing; It is More Than an Ice-Cold Shock; and Finding Mental Peace in Winter Bathing. The results suggest that winter bathing in blue spaces contributed to improved mental health for the informants. CONCLUSIONS: In conclusion, regular winter bathing enhanced the participants' mental health. A relatively short time in the ice-cold water provided mental peace which transferred to the rest of daily life in general, which emphasizes the mental health-promoting potential of winter bathing. Positive emotions were cultivated through exposure to blue spaces, including inner calm and a sense of safety. Winter bathing also served as a space for social connectedness and community building, facilitated by the club environment in which meaningful social interactions occurred.
RESUMEN
Based on bee foraging behaviour, the Bees Algorithm (BA) is an optimisation metaheuristic algorithm which has found many applications in both the continuous and combinatorial domains. The original version of the Bees Algorithm has six user-selected parameters: the number of scout bees, the number of high-performing bees, the number of top-performing or "elite" bees, the number of forager bees following the elite bees, the number of forager bees recruited by the other high-performing bees, and the neighbourhood size. These parameters must be chosen with due care, as their values can impact the algorithm's performance, particularly when the problem is complex. However, determining the optimum values for those parameters can be time-consuming for users who are not familiar with the algorithm. This paper presents BA1, a Bees Algorithm with just one parameter. BA1 eliminates the need to specify the numbers of high-performing and elite bees and other associated parameters. Instead, it uses incremental k-means clustering to divide the scout bees into groups. By reducing the required number of parameters, BA1 simplifies the tuning process and increases efficiency. BA1 has been evaluated on 23 benchmark functions in the continuous domain, followed by 12 problems from the TSPLIB in the combinatorial domain. The results show good performance against popular nature-inspired optimisation algorithms on the problems tested.
RESUMEN
BACKGROUND/OBJECTIVES: This study aimed to investigate the acute effects of a single session of a VR exergame (Beat Saber) and a VR nature video (Ireland 4K) on attentional performance, using the Flanker and Attentional Blink (AB) tasks. The objective was to assess whether these VR interventions could enhance attentional control, as measured by improvements in response times and accuracy. METHODS: A total of 39 psychology students, aged 19-25, were randomly assigned to one of three groups: VR exergame, VR nature video, or control. Participants completed the Flanker and AB tasks before and after the intervention. A repeated measures design was employed to analyze changes in response times and accuracy across pre- and post-test sessions. RESULTS: The study revealed significant improvements in response times and accuracy across all groups in the post-test measures, indicating a strong training effect. In the AB task, shorter stimulus onset asynchrony (SOA) led to decreased accuracy and slower response times, emphasizing the difficulty in processing closely spaced targets. The interaction between Type and Group in response times for target stimuli suggested that the intervention types differentially influenced processing speed in specific conditions. CONCLUSIONS: The findings suggest that while brief VR interventions did not produce significant differences between groups, the training effect observed highlights the influence of task-specific factors such as SOA and target presence. Further research is needed to explore whether longer or repeated VR sessions, as well as the optimization of task-specific parameters, might lead to more pronounced cognitive benefits.
RESUMEN
There is a common misconception that aquatic macrophytes face significant challenges in wetland-based sewage treatment systems. This study aims to correct this perception by focusing on the crucial morphophysiological adaptations of aquatic macrophytes that enable them to thrive in wetland-based sewage treatment systems, particularly under environmental stress. These adaptations are vital for improving the efficiency and resilience of wastewater treatment processes, offering sustainable solutions in the face of variable environmental conditions and complex contaminant mixtures. The review emphasizes the role of macrophytes as natural engineers, capable of enhancing pollutant removal and system stability through their unique structural and functional traits. By understanding these adaptations, the review aims to guide the optimization of wetland design and management, ultimately contributing to more sustainable and effective wastewater treatment practices. The findings underscore the importance of species selection and the integration of nature-based solutions in environmental management, advocating for policies that support the use of macrophytes in modern wastewater management.
RESUMEN
Background: Based on the examination of specimens of Amolopsminutus Orlov & Ho, 2007 and A.ottorum Pham, Sung, Pham, Le, Zieger & Nguyen, 2019, we found that there is no significant morphological difference between them. Phylogenetic analysis also showed that A.minutus and A.ottorum belong to the same taxon. In addition, we discovered the distribution of A.minutus in China. New information: In this study, we provide the first molecular data of Amolopsminutus and regard A.ottorum as a junior synonym of A.minutus. In addition, we report the first record of A.minutus from China, based on nine specimens collected from Guanyinshan Provincial Nature Reserve in southern Yunnan Province and present an updated diagnosis of this species, based on literature data and newly-collected specimens.
RESUMEN
Skin cancer, a prevalent malignancy worldwide, poses significant health concerns owing to its increasing incidence. Autophagy, a natural cellular process, is a pivotal event in skin cancer and has advantageous and detrimental effects. This duality has prompted extensive investigations into medical interventions targeting autophagy modulation for their substantial therapeutic potential. This systematic review aimed to investigate the relationship between skin cancer and autophagy and the contribution and mechanism of autophagy modulators in skin cancer. We outlined the effectiveness and safety of targeting autophagy as a promising therapeutic strategy for the treatment of skin cancer. This comprehensive review identified a diverse array of autophagy modulators with promising potential for the treatment of skin cancer. Each of these compounds demonstrates efficacy through distinct physiological mechanisms that have been elucidated in detail. Interestingly, findings from a literature search indicated that none of the natural, synthetic, or semisynthetic compounds exhibited notable adverse effects in either human or animal models. Consequently, this review offers novel mechanistic and therapeutic perspectives on the targeted modulation of autophagy in skin cancer.