Nanoscale octopus guiding telomere entanglement: An innovative strategy for inducing apoptosis in cancer cells.

Telomere length plays a crucial role in cellular aging and the risk of diseases. Unlike normal cells, cancer cells can extend their own survival by maintaining telomere stability through telomere maintenance mechanism. Therefore, regulating the lengths of telomeres have emerged as a promising approach for anti-cancer treatment. In this study, we introduce a nanoscale octopus-like structure designed to induce physical entangling of telomere, thereby efficiently triggering telomere dysfunction. The nanoscale octopus, composed of eight-armed PEG (8-arm-PEG), are functionalized with cell penetrating peptide (TAT) to facilitate nuclear entry and are covalently bound to N-Methyl Mesoporphyrin IX (NMM) to target G-quadruplexes (G4s) present in telomeres. The multi-armed configuration of the nanoscale octopus enables targeted binding to multiple G4s, physically disrupting and entangling numerous telomeres, thereby triggering telomere dysfunction. Both in vitro and in vivo experiments indicate that the nanoscale octopus significantly inhibits cancer cell proliferation, induces apoptosis through telomere entanglement, and ultimately suppresses tumor growth. This research offers a novel perspective for the development of innovative anti-cancer interventions and provides potential therapeutic options for targeting telomeres.

Characterization and function of particulate organic matter: Evidence from lakes undergoing ecological restoration.

Particulate organic matter (POM) plays a crucial role in the organic composition of lakes; however, its characteristics remain poorly understood. This study aimed to characterize the structure and composition of POM in Lake Baiyangdian using many kinds of techniques and investigate the effects of different extracted forms of POM on water quality. The suspended particulate matter in the lake had complex compositions, with its components primarily derived from aquatic plants and their detritus. The organic matter content of the suspended particulate matter was relatively high (organic carbon content 27.29-145.94 g/kg) for the sum of three extractable states (water-extracted organic matter [WEOM], humic acid, and fulvic acid) and one stable bound state (humin). Spatial distribution analysis revealed that the POM content in the water increased from west to east, which was consistent with the water flow pattern influenced by the Baiyangdian water diversion project. Fluorescence spectroscopy analysis of the WEOM showed three prominent peaks with excitation/emission wavelengths similar to those of dissolved organic matter peaks. These peaks were potentially initial products of POM conversion into dissolved organic matter. Furthermore, the intensity of the WEOM fluorescence peak (total fluorescence peak intensity) was negatively correlated with the inorganic nitrogen concentration in water (p < 0.01), while the intensity of the HA fluorescence peak showed a positive correlation with the inorganic nitrogen concentration (p < 0.01). This suggested that exogenous organic matter inputs led to the diffusion of alkaline dissolved nitrogen from sediment into water, while degradation processes of aquatic plant debris contributed to the decrease in inorganic nitrogen concentrations in the water column. These findings enhance our understanding of POM characteristics in shallow lakes and the role of POM in shallow lake ecosystems.

Protonated carbon nitride for rapid photocatalytic sterilization via synergistic oxidative damage and physical destruction.

Photocatalytic disinfection is an eco-friendly strategy for countering bacterial pollution in aquatic environments. Numerous strategies have been devised to facilitate the generation of reactive oxygen species (ROS) within photocatalysts, ultimately leading to the eradication of bacteria. However, the significance of the physical morphology of photocatalysts in the context of sterilization is frequently obscured, and the progress in the development of physical-chemical synergistic sterilization photocatalysts has been relatively limited. Herein, graphitic carbon nitride (g-C3N4) is chemically protonated to expose more sharp edges. PL fluorescence and EIS results indicate that the protonation can accelerate photogenerated carrier separation and enhance ROS production. Meanwhile, the sharp edges on the protonated g-C3N4 facilitate the physical disruption of cell walls for further promoting oxidative damage. Protonated C3N4 demonstrated superior bactericidal performance than that of pristine g-C3N4, effectively eliminating Escherichia coli within 40 minutes under irradiation. This work highlights the significance of incorporating physical and chemical synergies in photocatalyst design to enhance the disinfection efficiency of photocatalysis.

Yoga como terapia complementaria para el Adulto Mayor / Yoga as a complementary therapy for older adult

Introducción: El yoga es una actividad que trata de un ejercicio el cual contiene una intensidad baja a moderada, la cual no se centra exclusivamente en el entrenamiento físico, sino que también en el desarrollo de la mente y el espíritu de uno mismo. El yoga puede obtener un mayor impacto en el equilibrio y en la ganancia de fuerza de la parte superior del cuerpo, además, demuestra mejora en la aptitud cardiorrespiratoria y flexibilidad. Metodología: El enfoque de desarrollo fue de tipo cuantitativo en donde se realizó una revisión sistemática como metodología de búsqueda de información, relacionada al yoga como una terapia complementaria y los beneficios que éste aportaba al bienestar de las personas mayores. Resultados: En cada uno de los ensayos controlados aleatorizados que fueron recabados para fines de esta revisión sistemática. Se destaca la importancia y los beneficios del yoga en la movilidad, fuerza, flexibilidad y espiritualidad de los usuarios que practican esta terapia. Discusión: Los artículos analizados pertenecen a ensayos clínicos o estudios aleatorizados, los cuales permitieron responder de manera efectiva a nuestra pregunta de investigación, la cual consiste en reconocer si el yoga es efectivo para disminuir el riesgo de dependencia funcional y eliminar hábitos que no son saludables para las personas mayores, además de mejorar la calidad de vida actual. Gracias a ello se pudo evidenciar que esta terapia en adultos mayores genera cambios positivos respecto a estado y condición física, la ejecución de esta práctica mejora la calidad de vida en un 80% Conclusión: La yoga como terapia complementaria si entrega beneficios en la calidad de vida de la población adulta mayor, dado que, que hubo una mejora tanto en la movilidad, calidad de vida y autovalencia de los adultos mayores[AU]

Introduction: Yoga is an activity that deals with a low to moderate intensity exercise, which is not exclusively focused on physical training, but also on the development of the mind and spirit itself. Yoga may have a greater impact on balance and upper body strength gains, and have shown improvements in cardiorespiratory fitness and flexibility. Methodology:the development approach was of a quantitative type where a systematic review was carried out as a methodology for searching for information related to yoga as a complementary therapy and the benefits that it brought to the well-being of the elderly. Results:The importance and benefits of yoga on the mobility, strength, flexibility and spirituality of users who practice this therapy are highlighted in each of the randomized controlled trials that were collected for the purposes of this systematic review. Discussion: The articles analyzed belong to clinical trials or randomized studies, which allowed us to effectively answer our research question. The activity of yoga in older adults generates positive changes regarding state and physical condition, the execution of this practice improves the quality of life by 80% Conclusion: Yoga as a complementary therapy delivers benefits in the quality of life of the adult population elderly, it can be said that there was an improvement in mobility, quality of life and self-valence of the elderly[AU]

Introdução: O Yoga é uma atividade que trata de um exercício de intensidade baixa a moderada, que não se foca exclusivamente no treino físico, mas também no desenvolvimento da mente e do espí-rito. A ioga pode ter um impacto maior no equilíbrio e nos ganhos de força da parte superior do corpo e mostrou melhorias na apti-dão cardiorrespiratória e flexibilidade. Metodologia: a abordagem de desenvolvimento foi do tipo quantitativo onde foi realizada uma revisão sistemática como metodologia de busca de informações re-lacionadas ao yoga como terapia complementar e os benefícios que trouxe para o bem-estar dos idosos. Resultados: A importância e os benefícios do yoga na mobilidade, força, flexibilidade e espiri-tualidade dos usuários que praticam esta terapia são destacados em cada um dos ensaios clínicos randomizados que foram coletados para fins desta revisão sistemática. Discussão: Os artigos analisa-dos pertencem a ensaios clínicos ou estudos randomizados, o que nos permitiu responder de forma eficaz à nossa questão de inves-tigação. A atividade de yoga em idosos gera mudanças positivas quanto ao estado e condição física, a execução desta prática mel-hora a qualidade de vida em 80% Conclusão: o yoga como terapia complementar traz benefícios na qualidade de vida da população adulta idosa, pode-se dizer que houve melhora na mobilidade, qualidade de vida e autovalência dos idosos[AU]

Associations of sugar-sweetened beverage consumption and screen time with physical fitness index: a multicentre cross-sectional study among Chinese adolescents.

BACKGROUND: Past research has focused on the analysis of the association between sugar-sweetened beverages consumption and screen time, respectively, and an indicator of physical fitness in adolescents. However, no studies have analyzed the interaction between sugar-sweetened beverage consumption and screen time on physical fitness index. METHODS: Demographic information, lifestyle, sugar-sweetened beverage consumption and screen time were investigated and physical fitness indicators were tested in 8136 adolescents aged 13-18 years from six geographic regions of China using stage-stratified whole population sampling. The chi-square test and one-way ANOVA were used to compare the covariates. The Kruskal-Wallis test was used to compare physical fitness index between different sugar-sweetened beverage consumption and screen time groups. Generalized linear model ordered logistic regression analysis was used to analyze the interaction between sugar-sweetened beverage consumption and ST on physical fitness index. RESULTS: The differences in physical fitness index among different sugar-sweetened beverage consumers in child adolescents were all statistically significant in boys, girls, and in total (H-value of 72.415, 16.859, and 78.544, P < 0.001). The differences were also statistically significant when comparing the physical fitness index of Chinese adolescents of different screen time in boys, girls, and total (H-Value of 46.307, 21.552, and 65.287, P < 0.001). Overall, using sugar-sweetened beverage consumption ≤ 1time/week and screen time < 60 min/d as the reference group, after adjusting for relevant covariates, adolescents in the group with an sugar-sweetened beverage consumption of ≥ 5 time/week and screen time > 120 min/d (OR = 2.27, 95% CI:1.78, 2.89) had the the highest risk of reduced physical fitness index (P < 0.001 ). CONCLUSION: Associations of sugar-sweetened beverage consumption and screen time with physical fitness indices among Chinese adolescents. Both increased sugar-sweetened beverage consumption and prolonged ST further increased the risk of lower physical fitness index in adolescents.

Study protocol: process and outcome evaluation of the Walk with Ease program for fall prevention.

BACKGROUND: Falls are the leading cause of injury related morbidity and mortality in older adults. Primary and secondary prevention strategies that address modifiable risk factors are critically important to reduce the number of falls and fall related injuries. A number of evidence-based fall prevention programs are available, but few offer potential for broad dissemination and public health impact due to implementation barriers, such as a need for trained program leaders and clinicians. METHODS: The study will use a randomized controlled trial design to evaluate incorporating physical therapy exercises (primary prevention strategy) within an existing intervention called Walk with Ease. While Walk with Ease has an established evidence-base related to the management of arthritis pain and symptoms, the present study will determine the potential to also reduce falls and fall risk in community-dwelling older adults. The integrated process and outcome evaluation will determine the relative effectiveness of individually-prescribed exercises (compared to standardized exercises) as well as the potential of 'habit training' resources (relative to generic behavior prompts) to improve compliance with exercises in this population. DISCUSSION: The study, conducted through a local clinical-community partnership will advance both the science and practice of community-based fall prevention programming, while also informing implementation strategies needed to promote broader dissemination. TRIAL REGISTRATION: ClinicalTrials.gov, NCT05693025, Registered January 20, 2023, Updated March 1, 2023.

OPTIMAL Motor Teaching Strategies Employed in Physiotherapy for Children with Developmental Coordination Disorder: An Observational Study.

AIMS: To describe the teaching strategies that physiotherapists currently employ in individual therapy sessions for children with DCD using the OPTIMAL theory for motor learning as a framework, focused on (1) autonomy (supporting autonomy vs. therapist-controlled), (2) expectancies (enhancing vs. lowering expectancies), and (3) attention (promoting an internal vs. an external focus of attention). METHODS: Eighteen physiotherapy sessions were videotaped and analyzed with Noldus The Observer XT using the OPTIMAL Strategies Observational Tool (OSOT). Relative duration (% of session time) and frequency were extracted for teaching strategies related to autonomy, expectancies, and attention. RESULTS: Physiotherapists mostly applied strategies to support autonomy and enhance expectancies in contrast to therapist-controlled strategies, and lowering expectancies. Strategies to promote either an internal or an external focus of attention were used to a similar extent. Furthermore, strategies were frequently combined; physiotherapists often employed more than one teaching strategy at a time. CONCLUSIONS: The insight into current physiotherapy teaching practice that this study provides can help inform research and application regarding effective motor teaching for children with DCD. Follow up studies are needed to further investigate how child and task characteristics influence teaching strategy employment and to examine physiotherapists' reasoning behind their choice of strategies.

Influence of sustainable waste granite, marble and nano-alumina additives on ordinary concretes: a physical, structural, and radiological study.

This study investigates the individual and combined effects of enhancing the radiation shielding properties of waste concrete using the optimal mix design of two waste material powders of different compositions. Marble (MD) and granite (GD) waste dust were individually utilized as partial replacements for cement at a replacement ratio of 6%. Furthermore, two additional mixes were prepared by incorporating 1% by cement weight of nano alumina (NA) to enhance the microstructure of the studied waste concrete. The MGA-concrete was analyzed using X-ray Fluorescence, Energy dispersive X-ray, X-ray diffraction analysis, transmission electron microscopy, and scanning electron microscope techniques. The radiation shielding assets of the examined Concrete samples, such as the linear attenuation coefficient (µ), half value layer (H1/2), tenth value layer (T1/10), and fast neutron removal cross-section were evaluated using the MCS5 Monte Carlo simulation algorithm and Phy-X software. The results showed that the linear attenuation for the GMN-concretes' order is CO < MD < GD < NA < MD + NA < GD + NA. The GD + Na concrete sample presents the best neutron performance. The studied GMN-concrete samples provide the best protection against γ-rays and fast neutrons. Lastly, the excellent performance of the mixes of waste Granite, Marble, and Nano-Alumina on ordinary would pave the way for their employment as radiation shielding in various nuclear and medical facilities.

Change of direction and linear speed relation to functional ability and joint mobility in Polish U19 volleyball and basketball 3 × 3 national teams.

The purpose of this study was to determine the extent of differences in the level of change in linear speed and velocity in the modified change of direction test (COD) and to determine the relationship between speed deficits resulting from changes of direction and functional performance between groups of Polish U19 Volleyball National Team and Polish Women's Basketball 3 × 3 National Team. A total of 23 athletes: 12 volleyball players (age: 18 ± 0 years; body height: 183 ± 7 cm; body weight: 70 ± 8 kg) and 11 basketball players (age: 26 ± 4 years; body height: 180 ± 6 cm; body weight: 73 ± 10 kg) participated in the study. Athletes were tested for the following measures: Functional Movement Screen test (FMS), dynamic balance test Y-Balance, joints range of motion measurements, maximal sprint test (14 m), modified COD test (14 m) and change of direction deficit (CODD). A value of p < 0.05 was considered statistically significant. There was no significant correlation between sprint and CODD results in basketball team. In volleyball team there was a positive and significant correlation between COD, sprint and CODD. There was a negative and significant correlation between Y-Balance scores and sprint test results in the basketball team. Basketball team had a positive significant correlation between hip rotations and COD results. There was a negative significant correlation between shoulder movements and COD and CODD results in volleyball team.

An analytical study on changes in university students' attitudes toward physical activity.

Purpose: Positive attitudes toward physical activity have been consistently linked to health Behaviors. This study aims to validate the effectiveness of attitude change in the domain of exercise and identify the mechanisms through which this change occurs in the context of sports and promote exercise behavior. Methods: 103 university students (20.7 ± 1.97 years, 40 males, and 63 females) completed the implicit and explicit attitude tests. Based on their exercise levels assessed using the Physical Activity Rating Scale (PARS-3), participants were categorized into low and high exercise level groups. From this sample, 66 university students (19 males and 47 females) with low exercise levels completed a self-generated information task. Subsequently, physical activity was assessed through a skipping rope task. Results: The implementation of the self-generated information task resulted in notable alterations in implicit attitudes (ηi2 = 0.07) toward physical activity during subsequent Implicit Attitude Test (IAT) evaluations. Additionally, significant changes were observed in explicit attitudes (ηe2 = 0.12) toward physical activity among university students. Moreover, the use of self-generated information positively influenced immediate exercise behavior. Discussion: This study provides valuable insights into the impact of attitudes on behaviors among university students. It suggests that attitudes toward physical activity can be effectively changed through the use of self-generated information methodology, leading to an enhancement in immediate exercise behavior. Such attitude change has the potential to promote healthier behaviors and reduce the risk of diseases. These findings hold implications for interventions aimed at enhancing physical activity levels among university students.

Correspondence between the Simple Physical Activity Questionnaire (SIMPAQ) and accelerometer-based physical activity in inpatients treated for major depressive disorders in comparison to non-depressed controls.

Introduction: Major depressive disorders (MDD) are a leading health concern worldwide. While first line medication treatments may fall short of desired therapeutic outcomes, physical activity (PA) interventions appear to be a promising and cost-effective add-on to improve symptoms of depression. This study aimed to address challenges in the assessment of PA in inpatients treated for MDD by examining the correspondence of self-reported and accelerometer-based PA. Methods: In 178 inpatients treated for MDD (mean age: M = 41.11 years, SD = 12.84; 45.5% female) and 97 non-depressed controls (mean age: M = 35.24 years, SD = 13.40; 36.1% female), we assessed self-reported PA via the Simple Physical Activity Questionnaire (SIMPAQ) for one week, followed by a week where PA was monitored using an accelerometer device (Actigraph wGT3x-BT). Additionally, we examined correlations between PA levels assessed with the SIMPAQ and exercise determinants in both groups. Results: Descriptively, inpatients treated for MDD showed lower levels of light PA on accelerometer-based measures, whereas they self-reported increased levels of certain types of PA on the SIMPAQ. More importantly, there was only a small degree of correspondence between self-reported and actigraphy-based PA levels in both in patients (r = 0.15, p < 0.05) and controls (r = 0.03, ns). Only few significant correlations were found for self-reported PA (SIMPAQ subscores) and perceived fitness, whereas self-reported PA and estimated VO2max were unrelated. Furthermore, only weak (and mostly statistically non-significant) correlations were found between exercise determinants and SIMPAQ-based exercise behavior in both populations. Discussion: Our findings emphasize the intricate challenges in the assessment of PA, not only in inpatients treated for MDD, but also in non-depressed controls. Our findings also underline the necessity for a diversified data assessment. Further efforts are needed to refine and improve PA questionnaires for a more accurate data assessment in psychiatric patients and healthy controls.

How physical exercise with others and prioritizing positivity contribute to (work) wellbeing: a cross-sectional and diary multilevel study.

Introduction: This work is a dual study employing a cross-sectional approach and a diary method to investigate how physical exercise can become a habit. Guided by the Upward Spiral Theory of Lifestyle Change, we examined the role of prioritizing positivity and engaging in physical exercise with others as advantageous resources and their impact on the relational loop of physical exercise behavior, emotions, and engagement. Methods: The first study involved a sample of 553 participants, and the second study included 146 participants, all of whom were employed and regularly engaged in physical exercise. We utilized structural equation modeling and multilevel analysis for the respective studies. Results: The results of the first study indicate that individuals exercise more when they experience higher levels of engagement and positive emotions, particularly when exercising with others and prioritizing positivity. The findings of the second study reveal that prioritizing positivity acts as a precursor to positive emotions during physical exercise, which in turn reinforces the relational loop between emotions and exercise behavior. Discussion: Both studies conclude that individuals who prioritize positivity experience better psychological wellbeing and higher engagement in physical exercise.

The effects of mindfulness enhanced Tai Chi Chuan training on mental and physical health among beginners: a randomized controlled trial.

Introduction: Tai Chi Chuan (TCC) is a traditional Chinese mind-body exercise widely adopted in Chinese communities and colleges. However, the mindful essence of TCC is rarely emphasized during popularization. This makes it difficult for beginners to benefit from it. The present study aimed to examine the effects of a Mindfulness-enhanced Tai Chi Chuan (MTCC) intervention, which enhances mindfulness components embedded within TCC, on mental and physical health among beginners. Methods: A randomized controlled trial was conducted with 119 healthy college students new to Tai Chi Chuan training. Participants were assigned to either the MTCC group or the TCC group. Both interventions consisted of 10 weekly 90-min training sessions, with the MTCC group emphasizing and enhancing mindfulness components. Outcome measures included mindfulness, depression, anxiety, stress, and physical fitness, assessed at baseline and post-intervention. Results: The results showed that the MTCC group had significantly greater improvements than the TCC group in mindfulness, anxiety, stress, and health-and skill-related physical fitness. There were no significant differences between the two groups in depression. Conclusion: The findings suggest that compared to TCC, MTCC can effectively promote individuals' physical fitness and provide additional benefits to mental well-being. MTCC can be recommended as an accessible and beneficial intervention for beginners to improve mental health and strengthen their bodies. Clinical review registration: https://www.chictr.org.cn/, identifier ChiCTR2200058175.

Dissecting the causal relationship between moderate to vigorous physical activity levels and cognitive performance: a bidirectional two-sample Mendelian randomization study.

Introduction: Recent studies increasingly suggest that moderate-to-vigorous physical activity (MVPA) impacts cognitive risk. However, the bidirectional nature of this relationship warrants further exploration. To address this, we employed a Mendelian randomization (MR) approach, analyzing two distinct samples. Methods: These analyses utilized published genome-wide association study (GWAS) summary statistics for MVPA (n = 377,234) and cognitive performance (n = 257,841). Our primary method was the inverse variance weighted (IVW) model with random effects, aiming to deduce potential causal links. Additionally, we employed supplementary methods, including MR Egger regression, Weighted median, Weighted mode, and Simple mode. For sensitivity analysis, tools like the MR Egger test, Cochran's Q, MR PRESSO, and leave-one-out (LOO) were utilized. Results: Our findings indicate a decrease in cognitive risk with increased MVPA (Odds Ratio [OR] = 0.577, 95% Confidence Interval [CI]: 0.460-0.723, p = 1.930 × 10-6). Furthermore, enhanced cognitive levels corresponded to a reduced risk of inadequate MVPA (OR = 0.866, 95% CI: 0.839-0.895, p = 1.200 × 10-18). Discussion: In summary, our study demonstrates that MVPA lowers cognitive risk, while poor cognitive health may impede participation in MVPA. Overall, these findings provide valuable insights for developing personalized prevention and intervention strategies in health and sports sciences.

Association of Physical Fitness With the Work Ability of Aging Workers With Physically Demanding Jobs in a University Hospital in Thailand.

Background: A decrease in physical fitness with age can impact work ability. Exploring the role of physical fitness is important for identifying interventions to enhance work ability among aging workers. We sought to determine the association between physical fitness and physically demanding work ability in aging workers. Methods: We recruited workers aged 45-65 years from eight departments of a university hospital in Bangkok, Thailand. Work ability was assessed using the work ability index (WAI), and physical fitness components were evaluated through various tests. Associations between work ability and physical fitness were examined using a multivariable regression analysis. Results: The response rate was 46.4% (n = 216). The mean WAI score was 41.6. Participants with an overweight or obese body mass index (BMI) had 1.8 (95% CI -3.1, -0.4) points lower WAI scores than did those within a healthy BMI range. A handgrip strength test revealed that participants in the good/very good group had 2.5 (95% CI: 0.6, 4.3) higher WAI scores than did those in the very poor/poor group. For a single-leg stance test, participants in the above-average group had 2.1 (95% CI: 0.7, 3.5) points greater WAI scores than did those in the below-average group. No significant associations were found between work ability and 3-min step, chair stand, or sit-and-reach test scores. Conclusion: The overall work ability of the participants was good. Body composition, muscle strength, and balance were associated with work ability. Promoting physical fitness is a viable strategy for enhancing work ability among aging workers.

Physical Activity and the Health of a Nation: A National Challenge and Collective Response.

Historic recruitment and retention challenges confront the U.S. military. In an invited panel discussion at Lifestyle Medicine 2023, we argued that widespread physical inactivity is contributing to these challenges, and that Lifestyle Medicine approaches should be part of the solution. Our aim in this commentary is to recapture the most salient messages from that discussion. First, we summarize significant epidemiologic studies that describe the scope of the problem among future recruits, current service members, and Veterans. Then, in the optimistic spirit that characterizes both the armed forces and Lifestyle Medicine communities, we outline several potential solutions. By increasing physical activity during the school day, using wearable technology to monitor and prompt health behaviors, addressing the other pillars of Lifestyle Medicine (especially sleep, nutrition, and stress management), aligning efforts with current health frameworks in the Departments of Defense and Veterans Affairs, and recruiting Lifestyle Medicine professionals, we are convinced that we can improve the health of our nation and, in so doing, strengthen military readiness and national security.

The association of physical activity duration and intensity on emotional intelligence in 10-13 year-old Children.

Previous studies have shown that Physical Activity (PA) has a positive association with emotional health and intelligence in adolescents but none have focused on the relationship of PA duration and intensity on Emotional Intelligence (EI). The purpose of this study was to cross-sectionally assess the association of PA measures on overall EI and its domains in a cohort of 2 029 adolescents aged 10-13 years of age in the National Longitudinal Survey for Children and Youth (NLSCY) from Canada. Multivariable linear regression analysis of EI was adjusted for age, sex, annual household income, and health status. One-way analysis of variance (ANOVA) was used to relate PA duration measured in minutes, frequency, and intensity categories with continuous GEI scores and also the corresponding scores for domains of GEI. The mean GEI scores were (28.3 â€‹± â€‹6.6) for 0-30 â€‹minute (min) PA duration, (30.0 â€‹± â€‹6.5) for 30 to â€‹< â€‹60 â€‹min, (30.8 â€‹± â€‹6.7) for 60-120 â€‹min, and (30.1 â€‹± â€‹6.5) for ≥ 121 â€‹min. There was a statistically significant linear trend across PA duration categories, p â€‹= â€‹0.000 4. Post-hoc pairwise comparison revealed that compared to the referent category (< 30 â€‹min â€‹PA category) was statistically significantly lower GEI than each of the other two PA categories (30-59 â€‹min; and 60-120 â€‹min), both p-values < 0.01. Meeting World Health Organization (WHO) guidelines for duration and vigorous intensity were positively associated with the higher overall EI and its domains except for Stress Management.

Barriers and Facilitators Related to Undertaking Physical Activities in Colorectal Cancer Patients: A Scoping Review.

Background: Colorectal cancer (CRC) and its treatments cause significant acute, chronic, or latent adverse effects, leading to decreased physical function and quality of life. Robust evidence supports the positive effects of physical activity (PA) on various health outcomes in CRC patients. However, there is limited understanding regarding the factors that influence PA engagement, including facilitators, preferences, and barriers in this population. Purpose: This scoping review aims to document the breadth and depth of literature concerning the various aspects of PA participation among patients with CRC. We conducted a scoping review of PA among CRC patients. Methods: We searched several databases, including PubMed, Web of Science, Embase, and Cochrane, from their inception to 25 July 2023. Multiple reviewers were involved in all screening and data abstractions. The search yielded 834 individual citations after removing duplicates. After screening the titles and abstracts, 20 articles underwent full-text review, and 11 were included. Results: Our research findings indicate that among CRC patients, the most prevalent facilitators/preferences for PA are understanding its importance and perceiving its benefits, whereas treatment-related effects and lack of time are the most common barriers. Conclusion: CRC patients have unique facilitators and barriers concerning PA. Further research and clinical interventions are required to support and encourage this population to participate in and maintain regular PA.

Are physical activity and everyday mobility independently associated with quality of life at older age?

Background: Physical activity and everyday mobility are concepts that overlap but tend to be located in different disciplinary fields. We used the English Longitudinal Study of Ageing (ELSA) to: identify whether physical activity and everyday mobility are separate constructs at younger (60-69) and/or older (>=70) age bands, and for men and women; derive measures of the two constructs from variables in the ELSA; and assess whether they are independently associated with quality of life (QoL). Methods: We derived composite measures for physical activity and everyday mobility from ELSA variables. 'Physical Activity' combined items recording directly-measured activity for movement (walk-speed) and self-report measures of physical mobility difficulties and amount of vigorous, moderate and mild physical activity undertaken. 'Everyday Mobility' combined self-report responses about activities likely to involve leaving the house. QoL was measured using the 'CASP-19' scale. Using Wave 9 of ELSA (data collection in 2018-2020), we used a factor analysis to explore the constructs, and a regression analysis to examine associations with QoL. Results: The factor analysis confirmed that these were discrete constructs, which explained between them 36% of the variance. This was robust across age bands, and in factor analyses for men and women separately. The regression analysis identified that lower physical activity and everyday mobility are independently associated with lower QoL, when controlling for a range of contextual variables including age. Conclusions: Findings suggest that a social model of QoL at older age should focus on the broader mobility determinants of QoL as well as individual levels of physical activity.

Body composition, cardiovascular fitness and attention of school-aged male children practicing sports club activities: A cross-sectional.

BACKGROUND: The positive effects of physical activity on physical fitness, bone health, academic achievement, cognitive functions, mental health, and reduced obesity have been proven. This study aims to investigate the relationship between sports club activities, physical activity selected health-related fitness, and the d2 attention test. MATERIALS AND METHODS: A cross-sectional study was conducted in different sports clubs. A total of 78 male students aged 10-13 years participating in various branches of sports clubs were included in the study, 42 of whom were assigned to the sports group and 36 to the control group. Questionnaires were administered to assess sports club participation and attention levels, while physical health profiles were tested with body composition and Yo-Yo IR1C performance measures. Data were analyzed according to sports participation and the five most frequently reported sports. The means and standard deviation of each study value were calculated for the total subjects and by participating in sports activity using the IBM SPSS (version 23) analysis program. Data normality was checked and confirmed by the Skewness and Kurtosis Tests. RESULTS: The results showed that boys enrolled in a sports activity had lower body mass (-17.9%, P < 0.05 d = 0.72), body mass index (-13.4%, P < 0.05, d = 0.87), and body fat (%) (-54.1%, P < 0.05, d = 1.38) and higher VO2max 32.3% (P < 0.05, d = 3.67), than the non-active group. The boys active in sports clubs also had better results in the total number of items processed (11%, P < 0.05 d = 0.50) and in concentration performance (17.7%, P < 0.05 d = 0.56) than the non-active group. In correlation analyses, VO2max was negatively associated with body mass, body mass index, and body fat (P = 0.011; P = 0.001 and P = 0.00, respectively) and positively related to the total number of items processed and concentration performance (P = 0.003 and P = 0.015, respectively). In the Pearson Correlation analyses, body fat showed a lower negative correlation with TN (r = 0.33; P = 0.003) and CP (r = 0.28; P = 0.015). CONCLUSIONS: Boys participating in regular sports have lower body mass, BMI, and BF values. In addition, boys who participated in sports showed higher imaginary fitness and selective attention and concentration capacity results, as expected, for any sports part compared to their body peers. Another attempt from this study is that body mass and body fat percentage recovery are negatively associated with fitness. Considering the increasing prevalence of obesity in children and adolescents due to sedentary living, which has become a worldwide epidemic, it is recommended that pedagogical and public health strategies and policies be developed based on the physical fitness level of children.