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1.
Res Dev Disabil ; 145: 104658, 2024 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-38176290

RESUMEN

BACKGROUND: Developmental Coordination Disorder (DCD) is among the most under-recognized and under-supported disorders worldwide. AIMS: To present a preliminary national study that evaluated the unmet needs of children with DCD in the USA using the Impact for DCD survey. METHODS AND PROCEDURES: 232 parents of individuals aged 5-18 years provided responses from 36 items in five domains (diagnosis, activity/participation, education, therapy, and social/emotional health). OUTCOMES AND RESULTS: Most children (81.9%) had a formal diagnosis for movement difficulties, and 91.6% of parents reported that receiving a diagnosis was helpful, but most had not heard of the diagnosis before. The most common co-occurring diagnoses were childhood apraxia of speech and other speech-language disorders (24.6%), ADHD (23.1%), and anxiety (18.8%). Most parents reported that their children withdrew from or avoided movement-related activities (53%), and nearly all (94.8%) were concerned about the impact of motor difficulties on their children's social and emotional health. Only 37% of parents reported feeling that their child received sufficient therapy. CONCLUSIONS AND IMPLICATIONS: Generally, parents reported feeling frustrated with others' understanding and awareness of the condition and with therapy services. The results shown here provide timely data that can support efforts for increased awareness, improved diagnosis, and increased availability of services for DCD in the USA.


Asunto(s)
Apraxias , Trastornos de la Destreza Motora , Niño , Humanos , Estados Unidos/epidemiología , Trastornos de la Destreza Motora/diagnóstico , Trastornos de la Destreza Motora/epidemiología , Trastornos de la Destreza Motora/psicología , Apraxias/diagnóstico , Apraxias/epidemiología , Escolaridad , Movimiento , Encuestas y Cuestionarios
2.
J Clin Exp Neuropsychol ; 45(1): 84-103, 2023 02.
Artículo en Inglés | MEDLINE | ID: mdl-37039061

RESUMEN

INTRODUCTION: To investigate the role and influence of apraxia regarding dementia severity in Alzheimer's disease (AD). In addition, to examine whether apraxia or its association to dementia severity show distinct characteristics between typical and atypical variants of AD, that commonly include frontal, logopenic, posterior, and Down's syndrome variant. METHOD: The search conducted on 4 December 2020 in the Cinahl, Ovid Medline, PsycArticles, PsycInfo, Scopus and Web of Science databases yielded 251 non-duplicate records published since 2000. Ten records examining the association between Clinical Dementia Rating (CDR) scores and apraxia in AD were included in the review. RESULTS: Dementia severity was related to apraxia in AD, and the prevalence and severity of apraxia increased as dementia progressed. Constructional, ideomotor (imitation of meaningless gestures), orofacial, speech, gait, and total praxis, including constructional, ideomotor, and ideational praxis, tasks differentiated dementia severity in AD. In the atypical variants of AD apraxia occurred frequently but because of the small number of participants, no statistical analyses were available. CONCLUSIONS: The results highlight the need for extensive assessment of AD severity, and praxis assessment throughout the disease course. Apraxia affects the independent functioning and communication of the patient, tool use, and the ability to perform activities of daily living. Apraxia occurs frequently in AD and other neurodegenerative diseases, and apraxia assessment has shown to differentiate AD from other neurodegenerative diseases, particularly frontotemporal dementia. Thus, apraxia assessment serves in recognizing the atypical variants of AD as well.


Asunto(s)
Enfermedad de Alzheimer , Apraxias , Demencia Frontotemporal , Humanos , Enfermedad de Alzheimer/complicaciones , Actividades Cotidianas , Pruebas Neuropsicológicas , Apraxias/diagnóstico , Apraxias/epidemiología , Apraxias/etiología , Demencia Frontotemporal/complicaciones
3.
Psychiatr Danub ; 35(1): 47-55, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-37060592

RESUMEN

BACKGROUND: Almost 50% of patients with schizophrenia experience problems in their praxia performance, whereas executive function losses can be seen in patients with bipolar disorder. Although schizophrenia and bipolar disorder can be categorized as different disorders, in patient groups with similar symptom clusters, we aimed to determine whether there are common or disorder-specific praxia defects and to investigate the relationship between the sociodemographic and clinical features with apraxia. SUBJECTS AND METHODS: 52 Schizophrenia and 77 Bipolar Disorder Type I outpatients in remission for at least 6 months were included in our study. Test of Upper Limb Apraxia (TULIA) and Mayo Clinic Praxia Assessment Test (MCPAT) were used to evaluate praxia performance. RESULTS: Patients with Schizophrenia performed poorer on the TULIA and MCPAT than patients with Bipolar Disorder Type I. While impairment in personal and social functioning was higher in the apraxic schizophrenia group compared to the non-apraxic group, the mean age of disease onset was lower. Functioning in the Apraxic Bipolar Disorder Type I group was lower than in the group without apraxia; whereas the patient's age, duration of disease and number of hospitalizations were higher. CONCLUSIONS: Although apraxia, which have an important effect on the functioning and quality of life of the patient by causing impairment in daily activities, are seen at higher rates in patients with schizophrenia, might be also seen in patients with bipolar disorder type I. Decreasing diagnostic confusion and developing appropriate treatment strategies, evaluation of apraxia seems to be clinically important in terms of prognosis of diseases and functioning of patients.


Asunto(s)
Apraxias , Trastorno Bipolar , Esquizofrenia , Humanos , Esquizofrenia/diagnóstico , Esquizofrenia/epidemiología , Trastorno Bipolar/diagnóstico , Trastorno Bipolar/epidemiología , Calidad de Vida , Apraxias/diagnóstico , Apraxias/epidemiología , Pronóstico , Pruebas Neuropsicológicas
4.
J Speech Lang Hear Res ; 66(3): 791-803, 2023 03 07.
Artículo en Inglés | MEDLINE | ID: mdl-36795544

RESUMEN

PURPOSE: The purpose of this study was to investigate comorbidity prevalence and patterns in childhood apraxia of speech (CAS) and their relationship to severity. METHOD: In this retroactive cross-sectional study, medical records for 375 children with CAS (M age = 4;9 [years;months], SD = 2;9) were examined for comorbid conditions. The total number of comorbid conditions and the number of communication-related comorbidities were regressed on CAS severity as rated by speech-language pathologists during diagnosis. The relationship between CAS severity and the presence of four common comorbid conditions was also examined using ordinal or multinomial regressions. RESULTS: Overall, 83 children were classified with mild CAS; 35, with moderate CAS; and 257, with severe CAS. Only one child had no comorbidities. The average number of comorbid conditions was 8.4 (SD = 3.4), and the average number of communication-related comorbidities was 5.6 (SD = 2.2). Over 95% of children had comorbid expressive language impairment. Children with comorbid intellectual disability (78.1%), receptive language impairment (72.5%), and nonspeech apraxia (37.3%; including limb, nonspeech oromotor, and oculomotor apraxia) were significantly more likely to have severe CAS than children without these comorbidities. However, children with comorbid autism spectrum disorder (33.6%) were no more likely to have severe CAS than children without autism. CONCLUSIONS: Comorbidity appears to be the rule, rather than the exception, for children with CAS. Comorbid intellectual disability, receptive language impairment, and nonspeech apraxia confer additional risk for more severe forms of CAS. Findings are limited by being from a convenience sample of participants but inform future models of comorbidity. SUPPLEMENTAL MATERIAL: https://doi.org/10.23641/asha.22096622.


Asunto(s)
Apraxias , Trastorno del Espectro Autista , Discapacidad Intelectual , Trastornos del Desarrollo del Lenguaje , Niño , Humanos , Preescolar , Habla , Trastornos del Habla/epidemiología , Trastornos del Habla/diagnóstico , Estudios Retrospectivos , Estudios Transversales , Trastorno del Espectro Autista/epidemiología , Apraxias/epidemiología , Apraxias/diagnóstico , Comorbilidad , Trastornos del Desarrollo del Lenguaje/diagnóstico
5.
Cortex ; 151: 15-29, 2022 06.
Artículo en Inglés | MEDLINE | ID: mdl-35378419

RESUMEN

Apraxia of speech is a motor speech disorder that occurs after lesions to the left cerebral hemisphere, most often concomitant with aphasia. It requires specific approaches in the study of its physiological and neuroanatomical basis and special expertise in clinical care. Knowing its prevalence in patients with aphasia after stroke is therefore relevant for planning specific resources in clinical research and in health care provision. Systematic studies of the frequency of this condition are lacking. We examined the frequency of apraxia of speech in a representative sample of 156 patients with chronic post-stroke aphasia. Three experts classified the patients' speech by best-practice auditory-perceptual methods. Bayesian hierarchical models were fitted to obtain probability distributions for prevalence estimates. A prior distribution was calculated in two steps, including Bayesian models for published frequency data (step 1) and prevalence estimates from experienced clinicians (step 2). Separate models were fitted for different severity ranges. Overall, a prevalence rate of .44 [.30, .58] was obtained. When only moderate and severe cases were taken into account, the rate was .35 [.23, .49]. After a further restriction to only severe impairment, prevalence dropped to .22 [.12, .34]. Patients identified with apraxia of speech had suffered more severe strokes according to clinical criteria and had more severe aphasias. The presence of apraxia of speech was predicted by the articulation/prosody and syntax rating scales of the Aachen Aphasia Test. Lower prevalence estimates published earlier are probably biased by low sensitivity of assessment instruments for mild speech impairment.


Asunto(s)
Afasia , Apraxias , Accidente Cerebrovascular , Afasia/complicaciones , Afasia/etiología , Apraxias/epidemiología , Teorema de Bayes , Humanos , Prevalencia , Habla , Accidente Cerebrovascular/complicaciones , Accidente Cerebrovascular/epidemiología
6.
Am J Speech Lang Pathol ; 30(6): 2572-2588, 2021 11 04.
Artículo en Inglés | MEDLINE | ID: mdl-34609155

RESUMEN

Purpose Adolescent psychosocial outcomes of individuals with histories of childhood apraxia of speech (CAS) were compared to outcomes of individuals with histories of speech sound disorders (SSD) only and SSD with language impairment (LI). It was hypothesized that individuals with more severe and persistent disorders such as CAS would report poorer psychosocial outcomes. Method Groups were compared using analyses of variance on a psychosocial assessment battery that included measures of hyperactivity and inattention, anxiety, depression, internalizing and externalizing behaviors, thought problems, and social outcomes. Results Results revealed significant group differences on self-report of social problems and parent report of hyperactivity, thought problems, and social problems at adolescence. Compared to the SSD-only group, the CAS group had significantly higher parental ratings of hyperactivity and social problems in adolescence. The CAS and SSD + LI groups did not differ on psychosocial measures, possibly due to the high rate of comorbid LI in the CAS group. The CAS group also had more individuals who scored in the borderline/clinical range on self-report of social problems than the SSD-only group. The CAS group did not differ from the SSD + LI group in the number of participants scoring in the borderline/clinical range on measures. Conclusions Individuals with histories of CAS demonstrate increased rates of social problems and hyperactivity based on parent ratings compared to adolescents with histories of SSD only; however, most do not score within the clinical range. The persistence of speech sound errors combined with self-reported and parent-reported social difficulties suggests that speech-language pathologists should be sensitive to the social and emotional impact of CAS and make appropriate referrals to mental health professionals when warranted.


Asunto(s)
Apraxias , Trastornos del Lenguaje , Trastorno Fonológico , Adolescente , Apraxias/diagnóstico , Apraxias/epidemiología , Comorbilidad , Humanos , Trastornos del Lenguaje/diagnóstico , Trastornos del Lenguaje/epidemiología , Habla
7.
Int J Pediatr Otorhinolaryngol ; 145: 110742, 2021 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-33933988

RESUMEN

OBJECTIVE: to compare the Frequency Following Responses of children with childhood apraxia of speech with typical development children. METHOD: this is an observational cross-sectional analytical study approved by Human Research Ethics Committee. Thirty normal hearing children have participated in the study. THEY WERE DIVIDED INTO TWO GROUPS: 1) study group - composed by 15 children diagnosed with childhood apraxia of speech (between the chronological ages of 3 and 11 years, mean age of 5,7 years); and 2) control group: composed by 15 children with typical development, paired by age and gender with study group. Frequency Following Response were recorded using the/da/syllable presentation rate at 10.9 ms. RESULTS: there was a significant delay in latencies of waves V, A and C of children with apraxia of speech, suggesting difficulties in the ability to process sounds. CONCLUSION: The delay on Frequency Following Response's latencies (waves V, A and C) in children with apraxia of speech maybe related to atypical neural coding of speech sounds, suggesting that apraxia of speech must not be purely considered as a motor speech disorder.


Asunto(s)
Apraxias , Percepción del Habla , Apraxias/diagnóstico , Apraxias/epidemiología , Niño , Preescolar , Estudios Transversales , Potenciales Evocados Auditivos del Tronco Encefálico , Humanos , Fonética , Habla , Trastornos del Habla/diagnóstico , Trastornos del Habla/epidemiología
8.
J Geriatr Psychiatry Neurol ; 34(2): 150-155, 2021 03.
Artículo en Inglés | MEDLINE | ID: mdl-32292086

RESUMEN

Apraxia occurs frequently in patients with dementia. Buccofacial apraxia (BFA) characteristics have been less investigated than limb or speech apraxia. An association between BFA and oropharyngeal dysphagia (OD) in old patients with dementia has not yet been explored. We aimed to assess the prevalence of BFA in patients with dementia and evaluate the relationship between BFA, OD, and dementia. We have prospectively included 117 outpatients with dementia referred to a geriatric consultation. Oropharyngeal dysphagia was diagnosed using the volume viscosity swallowing test (V-VST). Buccofacial apraxia was evaluated by miming 7 meaningless gestures. A complementary geriatric assessment of 6-domains completed the evaluation. Buccofacial apraxia was present in 54 (48.6%) patients. Proxies reported OD more frequently in the group of patients with BFA compared to the group without (P = .04). Prevalence of OD assessed with the V-VST was similar between patients with and without apraxia (P = .9). Patients with BFA had a significant lower Mini-Mental State Examination suggesting a more severe cognitive decline (18.1 ± 4.5 vs 15.8 ± 5, P = .01), a lower activities of daily living relative to disabilities (5 ± 0.8 vs 4.3 ± 1.3, P = .001), and had a lower gait speed that indicated frailty (P = .03).In conclusion, our results indicate a relationship between BFA and severity of dementia, disability, and frailty with no significant association between BFA and OD.


Asunto(s)
Apraxias , Trastornos de Deglución , Demencia , Actividades Cotidianas , Anciano , Apraxias/diagnóstico , Apraxias/epidemiología , Trastornos de Deglución/diagnóstico , Trastornos de Deglución/epidemiología , Demencia/epidemiología , Humanos , Vida Independiente
9.
BMC Pediatr ; 20(1): 519, 2020 11 13.
Artículo en Inglés | MEDLINE | ID: mdl-33187500

RESUMEN

BACKGROUND: Childhood apraxia of speech (CAS) is a neurodevelopmental disorder with heterogeneous communication and other comorbid manifestations. While previous studies have characterized speech deficits associated with CAS, few studies have examined variability in reading and language and/or other developmental comorbidities. We sought to identify comorbid subgroups within CAS that could be clinically relevant as well as genetically distinctive. METHODS: In a group of 31 children with CAS and 8 controls, we performed hierarchical cluster analysis utilizing measures of articulation, vocabulary, and reading. We also conducted a chart review of the children with CAS to examine other clinical characteristics in these children and their association with subgroup membership. RESULTS: We identified 3 comorbid subgroups within CAS of varying severity. The high severity subgroup was characterized by poor reading and vocabulary, and the moderate severity subgroup by poor reading and non-word repetition but average vocabulary, compared to the mild severity subgroup. Subgroups were indistinguishable with respect to speech sound production, the hallmark of CAS, all demonstrating poor articulation. Children in the most severe subgroup were more likely to have early problems feeding (p = 0.036). CONCLUSIONS: Children with CAS may potentially be classified into comorbidity groups based on performance on vocabulary and reading measures, providing additional insight into the heterogeneity within CAS with implications for educational interventions.


Asunto(s)
Apraxias , Trastornos del Desarrollo del Lenguaje , Apraxias/diagnóstico , Apraxias/epidemiología , Niño , Humanos , Fonética , Habla , Trastornos del Habla/epidemiología
11.
Sleep ; 42(12)2019 12 24.
Artículo en Inglés | MEDLINE | ID: mdl-31581285

RESUMEN

STUDY OBJECTIVES: Early in life impairment of orofacial growth leads to sleep-disordered breathing (SDB). Normal lingual gnosis and praxis are part of this early development related to the normal sensorimotor development of the tongue and surrounding oral musculature. The aim of this retrospective study was to explore if lingual praxia is impaired in both SDB children and adults and if there is an association to craniofacial morphology. METHODS: The ability to perform simple tongue maneuvers was investigated in 100 prepubertal SDB children and 150 SDB adults (shown with polysomnography). All individuals had a clinical investigation by specialists to assess any orofacial growth impairment and the elements potentially behind this impairment. In a subgroup of individuals both able and unable to perform the maneuvers, we also performed a blind recognition of forms placed in the mouth. RESULTS: A subgroup of pediatric and adult SDB patients presented evidence not only of orofacial growth impairment, but also apraxia independent of age and severity of OSA. CONCLUSIONS: By 3 years of age, children should be able to perform requested tongue maneuvers and have oral form recognition. Abnormal gnosis-praxis was noted, independent of age in SDB children and adults, demonstrating that an abnormal functioning of the tongue in the oral cavity during early development can be detected. Both children and adults with SDB may present similar absences of normal oral development very early in life and a similar presentation of apraxia, suggesting that the distinction of SDB in children versus adults may not be relevant.


Asunto(s)
Apraxias/diagnóstico , Apraxias/fisiopatología , Polisomnografía/métodos , Apnea Obstructiva del Sueño/diagnóstico , Apnea Obstructiva del Sueño/fisiopatología , Lengua/fisiopatología , Adulto , Apraxias/epidemiología , Niño , Preescolar , Cognición/fisiología , Femenino , Humanos , Masculino , Persona de Mediana Edad , Estudios Retrospectivos , Apnea Obstructiva del Sueño/epidemiología , Lengua/crecimiento & desarrollo
12.
Clin Linguist Phon ; 33(8): 677-678, 2019.
Artículo en Inglés | MEDLINE | ID: mdl-31221008

RESUMEN

This introduction to a special issue of Clinical Linguistics & Phonetics includes an overview of the contents of each of the six articles. Each of the articles use the finalized version of the Speech Disorders Classification System (SDCS).


Asunto(s)
Apraxias/epidemiología , Trastornos del Desarrollo del Lenguaje , Trastornos del Neurodesarrollo/epidemiología , Trastornos del Habla/epidemiología , Apraxias/fisiopatología , Humanos , Masculino , Trastornos del Habla/clasificación , Trastorno Fonológico
13.
Clin Linguist Phon ; 33(8): 707-736, 2019.
Artículo en Inglés | MEDLINE | ID: mdl-31221012

RESUMEN

Estimates of the prevalence of speech and motor speech disorders in persons with complex neurodevelopmental disorders (CND) can inform research in the biobehavioural origins and treatment of CND. The goal of this research was to use measures and analytics in a diagnostic classification system to estimate the prevalence of speech and motor speech disorders in convenience samples of speakers with one of eight types of CND. Audio-recorded conversational speech samples from 346 participants with one of eight types of CND were obtained from a database of participants recruited for genetic and behavioural studies of speech sound disorders (i.e., excluding dysfluency) during the past three decades. Data reduction methods for the speech samples included narrow phonetic transcription, prosody-voice coding, and acoustic analyses. Standardized measures were used to cross-classify participants' speech and motor speech status. Compared to the 17.8% prevalence of four types of motor speech disorders reported in a study of 415 participants with idiopathic Speech Delay (SD), 47.7% of the present participants with CND met criteria for one of four motor speech disorders, including Speech Motor Delay (25.1%), Childhood Dysarthria (13.3%), Childhood Apraxia of Speech (4.3%), and concurrent Childhood Dysarthria and Childhood Apraxia of Speech (4.9%). Findings are interpreted to indicate a substantial prevalence of speech disorders, and notably, a substantial prevalence of motor speech disorders in persons with some types of CND. We suggest that diagnostic classification information from standardized motor speech assessment protocols can contribute to research in the pathobiologies of CND. Abbreviations: 16p: 16p11.2 deletion and duplication syndrome; 22q: 22q11.2 deletion syndrome; ASD: Autism Spectrum Disorder; CAS: Childhood Apraxia of Speech; CD: Childhood Dysarthria; CND: Complex Neurodevelopmental Disorder; DS: Down syndrome; FXS: Fragile X syndrome; GAL: Galactosemia; IID: Idiopathic Intellectual Disability; MSD: Motor Speech Disorder; No MSD: No Motor Speech Disorder; NSA: Normal(ized) Speech Acquisition; PEPPER: Programs to Examine Phonetic and Phonologic Evaluation Records; PSD: Persistent Speech Delay; PSE: Persistent Speech Errors; SD: Speech Delay; SDCS: Speech Disorders Classification System; SDCSS: Speech Disorders Classification System Summary; SE: Speech Errors; SMD: Speech Motor Delay; SSD: Speech Sound Disorders; TBI: Traumatic Brain Injury.


Asunto(s)
Apraxias/epidemiología , Trastornos del Desarrollo del Lenguaje/epidemiología , Trastornos del Neurodesarrollo/epidemiología , Trastornos del Habla/epidemiología , Trastorno Fonológico/epidemiología , Adolescente , Adulto , Niño , Femenino , Humanos , Masculino , Trastornos del Neurodesarrollo/fisiopatología , Habla/fisiología , Trastornos del Habla/clasificación
14.
Clin Linguist Phon ; 33(8): 679-706, 2019.
Artículo en Inglés | MEDLINE | ID: mdl-30987467

RESUMEN

The goal of this research was to obtain initial estimates of the prevalence of each of four types of motor speech disorders in children with idiopathic Speech Delay (SD) and to use findings to estimate the population-based prevalence of each disorder. Analyses were completed on audio-recorded conversational speech samples from 415 children recruited for research in idiopathic SD in six USA cities during the past three decades. The speech and motor speech status of each participant was cross-classified using standardized measures in the finalized version of the Speech Disorders Classification System described in the Supplement. Population-based prevalence estimates for the four motor speech disorders were calculated from epidemiological studies of SD conducted in Australia, England, and the USA. A total of 82.2% of the 415 participants with SD met criteria for No Motor Speech Disorder at assessment, 12% met criteria for Speech Motor Delay, 3.4% met criteria for Childhood Dysarthria, 2.4% met criteria for Childhood Apraxia of Speech, and 0% met criteria for concurrent Childhood Dysarthria and Childhood Apraxia of Speech. The estimated population-based prevalence of each of the first three motor speech disorders at 4 to 8 years of age were Speech Motor Delay: 4 children per 1,000; Childhood Dysarthria: 1 child per 1,000; and Childhood Apraxia of Speech: 1 child per 1,000. The latter finding cross-validates a prior prevalence estimate for Childhood Apraxia of Speech of 1-2 children per 1,000. Findings are interpreted to indicate a substantial prevalence of motor speech disorders in children with idiopathic SD. Abbreviations: CAS, childhood apraxia of speech; CD, childhood dysarthria; CND, complex neurodevelopmental disorders; DI, dysarthria index; DSI, dysarthria subtype indices; MSD, motor speech disorder; No MSD, no motor speech disorder; NSA, normal(ized) speech acquisition; PEPPER, programs to examine phonetic and phonologic evaluation records; PM, pause marker; PMI, pause marker index; PSD, persistent speech delay; PSE, persistent speech errors; SD, speech delay; SDCS, speech disorders classification system; SDCSS, speech disorders classification system summary; SE, speech errors; SMD, speech motor delay.


Asunto(s)
Apraxias/epidemiología , Trastornos del Desarrollo del Lenguaje/epidemiología , Trastornos del Habla/epidemiología , Niño , Preescolar , Femenino , Humanos , Masculino , Trastornos del Habla/clasificación , Estados Unidos/epidemiología
15.
Continuum (Minneap Minn) ; 25(1): 101-127, 2019 02.
Artículo en Inglés | MEDLINE | ID: mdl-30707189

RESUMEN

PURPOSE OF REVIEW: This article reviews two of the primary progressive aphasias (PPAs), disorders characterized by the early and predominant impairment of language, and primary progressive apraxia of speech, a degenerative motor speech disorder that is closely related to PPA. An outline of the history and controversy surrounding how these disorders are classified is provided before the article focuses on each disorder's clinical and imaging features. RECENT FINDINGS: Over the past decade, the classification of degenerative speech and language disorders has been refined. Clinical, imaging, and pathologic evidence suggests that primary progressive apraxia of speech is a distinct degenerative disorder. Furthermore, multiple lines of evidence have highlighted issues with nonfluent/agrammatic variant PPA, which complicates the diagnosis, prognosis, and study of this disorder. Semantic variant PPA, while not without controversy, remains one of the most well-defined disorders, with good clinicopathologic correlation. SUMMARY: Accurate classification and diagnosis of these degenerative speech and language disorders is crucial in clinical practice and ongoing research efforts. For nonfluent/agrammatic variant PPA, the authors suggest emphasizing agrammatism as the core inclusion criterion and taking care not to include patients with isolated or predominant apraxia of speech. Isolated apraxia of speech can be the manifestation of a degenerative disease and, based on the different prognosis, should be recognized as distinct from PPA. Finally, it is important to recognize that some patients with semantic dementia, despite sharing the same pathologic associations, may not meet criteria for PPA.


Asunto(s)
Afasia Progresiva Primaria/fisiopatología , Apraxias/fisiopatología , Habla/fisiología , Anciano , Afasia Progresiva Primaria/diagnóstico , Afasia Progresiva Primaria/epidemiología , Afasia Progresiva Primaria/genética , Apraxias/diagnóstico , Apraxias/epidemiología , Apraxias/genética , Encéfalo/diagnóstico por imagen , Femenino , Fluorodesoxiglucosa F18/farmacocinética , Demencia Frontotemporal/etiología , Humanos , Imagen por Resonancia Magnética , Examen Neurológico , Pruebas Neuropsicológicas , Tomografía de Emisión de Positrones
16.
Pediatr Neurol ; 92: 55-59, 2019 03.
Artículo en Inglés | MEDLINE | ID: mdl-30594525

RESUMEN

BACKGROUND: The association between left hemisphere stroke and acute speech and language impairment is well documented in adults. However, little is known about this association in childhood arterial ischemic stroke. Here we examined potential predictors of acute speech (dysarthria and apraxia) and language impairments after childhood arterial ischemic stroke, including site of lesion. METHODS: Children with radiologically confirmed acute arterial ischemic stroke, admitted to a tertiary pediatric hospital from 2004 to 2012, were identified from an institutional registry. We examined the prevalence of dysarthria, apraxia, and language impairment within two weeks of the stroke. Associations with age at stroke event, lesion side (left, right, or bilateral), and arterial territory affected (anterior, posterior, or both) were assessed using logistic regression. RESULTS: Sixty-two children with mean age eight years (range three to 17 years) were identified. Strokes were located in the left (32%), right (44%), or both hemispheres (24%). Dysarthria (74%) and language impairment (50%) were frequent. Verbal dyspraxia was less common (11%). There was little evidence that variables of interest, including site of lesion, were significantly associated with increased odds of dysarthria or language impairment (all P > 0.49). CONCLUSIONS: Regardless of age, children are at high risk of communication disorders after stroke. Unlike adults, left hemisphere stroke was not associated with either speech or language impairment in our cohort, suggesting there may be bihemispheric contribution to language function. Future studies are needed to examine whether the predictors examined here determine long-term outcomes.


Asunto(s)
Apraxias/fisiopatología , Isquemia Encefálica/fisiopatología , Lateralidad Funcional/fisiología , Enfermedades Arteriales Intracraneales/fisiopatología , Trastornos del Lenguaje/fisiopatología , Accidente Cerebrovascular/fisiopatología , Adolescente , Apraxias/epidemiología , Apraxias/etiología , Isquemia Encefálica/complicaciones , Isquemia Encefálica/epidemiología , Niño , Preescolar , Disartria/epidemiología , Disartria/etiología , Disartria/fisiopatología , Femenino , Humanos , Enfermedades Arteriales Intracraneales/complicaciones , Enfermedades Arteriales Intracraneales/epidemiología , Trastornos del Lenguaje/epidemiología , Trastornos del Lenguaje/etiología , Masculino , Riesgo , Accidente Cerebrovascular/complicaciones , Accidente Cerebrovascular/epidemiología
17.
Ugeskr Laeger ; 180(12)2018 Mar 19.
Artículo en Danés | MEDLINE | ID: mdl-29559079

RESUMEN

Childhood apraxia of speech and oral dyspraxia are subtypes of dyspraxia: a neurological motor disorder with absence of neuromuscular deficits. The core impairment is in planning and/or programming spatiotemporal parameters of movement sequences, which results in errors in speech sound production and prosody, or in oral motor movements and gestures. Correct diagnostics and focus on differential diagnoses and co-morbidity are crucial, as treatment differs from other types of speech- and oral motor disorders. Early and specialized intervention is recommended.


Asunto(s)
Apraxias , Adolescente , Apraxias/diagnóstico , Apraxias/epidemiología , Apraxias/terapia , Niño , Preescolar , Diagnóstico Diferencial , Humanos
18.
J Neonatal Perinatal Med ; 10(3): 257-266, 2017.
Artículo en Inglés | MEDLINE | ID: mdl-28854519

RESUMEN

OBJECTIVE: To study the quality of life at school age of very preterm infants presenting isolated punctate periventricular white matter lesions (IPWL) on late-preterm or term magnetic resonance imaging (MRI). METHODS: In 1996-2000, 16 of the 131 very preterm neonates explored by MRI were found to have IPWL. At the age of 9-14, 12 children from the IPWL group were compared with 54 children born preterm but with a normal MRI (no lesion). Quality of life (Health Status Classification System Pre School questionnaire), school performance, and motor outcome were investigated. RESULTS: Overall quality of life did not differ between the groups (classified as perfect in 2/12 of the IPWL vs 20/54 in the no-lesion). The sub-items mobility and dexterity differed significantly between the two groups, with impairment in the IPWL group (p < 0.001 and p < 0.05). This group also displayed higher levels of motor impairment: they began walking later [20(4) vs. 15(3) months), p < 0.01], had higher frequencies of cerebral palsy (6/12 vs. 2/54, p < 0.05), and dyspraxia (4/12 vs. 0/54, p < 0.001). The rate of grade retention did not differ between the groups (3/12 in the IPWL group vs. 17/54 in the no-lesions group) but, as expected, was higher than that of the French general population (17.4%) during the study period. CONCLUSION: This long-term follow-up study detected no increase in the risk of subsequent cognitive impairment in very preterm infants with IPWL, but suggests that these children may have a significantly higher risk of dyspraxia, and motor impairment.


Asunto(s)
Apraxias/epidemiología , Parálisis Cerebral/epidemiología , Leucoencefalopatías/diagnóstico por imagen , Calidad de Vida , Sustancia Blanca/diagnóstico por imagen , Adolescente , Encéfalo/diagnóstico por imagen , Niño , Femenino , Estudios de Seguimiento , Humanos , Recien Nacido Extremadamente Prematuro , Recién Nacido , Recien Nacido Prematuro , Imagen por Resonancia Magnética , Masculino
19.
Rev Neurol (Paris) ; 173(7-8): 430-439, 2017.
Artículo en Inglés | MEDLINE | ID: mdl-28844701

RESUMEN

Gestural apraxia was first described in 1905 by Hugo Karl Liepmann. While his description is still used, the actual terms are often confusing. The cognitive approach using models proposes thinking of the condition in terms of production and conceptual knowledge. The underlying cognitive processes are still being debated, as are also the optimal ways to assess them. Several neuroimaging studies have revealed the involvement of a left-lateralized frontoparietal network, with preferential activation of the superior parietal lobe, intraparietal sulcus and inferior parietal cortex. The presence of apraxia after a stroke is prevalent, and the incidence is sufficient to propose rehabilitation.


Asunto(s)
Apraxias , Apraxias/diagnóstico , Apraxias/epidemiología , Apraxias/etiología , Apraxias/terapia , Encéfalo/patología , Encéfalo/fisiopatología , Historia del Siglo XX , Historia del Siglo XXI , Humanos , Neuroimagen , Pruebas Neuropsicológicas , Desempeño Psicomotor , Accidente Cerebrovascular/complicaciones , Accidente Cerebrovascular/epidemiología , Accidente Cerebrovascular/terapia
20.
Rev Salud Publica (Bogota) ; 19(3): 297-303, 2017.
Artículo en Español | MEDLINE | ID: mdl-30183932

RESUMEN

OBJECTIVE: To establish the prevalence of the psychomotor profile in children aged four to eight years attending the schools of the North Historical Center of Barranquilla, Colombia. METHOD: A cross-sectional descriptive study was conducted in 755 students from public and private schools aged between 4 and 8 years. The motor profile was measured by Da Fonseca Psychomotor Battery. RESULTS: An increased risk for apraxic-dyspraxic performance of the global praxis subfactor was observed in schoolchildren aged four to five years [OR 4.8; 95 % CI; 3.3-7.1] who study in public schools [OR 4.4; 95 % CI; 2.7-7.3], in those classified in the socioeconomic in strata 1, 2 and 3 [OR 2.4; 95 % CI; 1.5-3.9], and in those with an increased weight [OR 2; 95 % CI; 1.2-3.3]. The highest risk for apraxic-dyspraxic performance correlated to public school students [OR 1.9; 95% CI; 1.3-2.8] aged between four and five [OR 3.7; 95 % CI; 2.7-5.3]. The apraxic-dyspraxic performance in the structuring of the temporal space subfactor was higher in girls [OR 1.6; 95 % CI; 1.1- 2.2], in schoolchildren aged four to five [OR 4.8; 95 % CI; 3.3-7.1], in students of public schools [OR 1.9; 95 % CI; 2.7- 5.3], and in children classified in the socioeconomic strata 1, 2 and 3 [OR 1.6; 95 % CI; 1.1-2.7]. CONCLUSIONS: Determinants such as studying in public schools, nutritional status, gender and socioeconomic stratum are related to motor performance in students.


OBJETIVO: Establecer la prevalência del perfil psicomotriz en niños de cuatro a ocho años de edad de los colegios de la localidad Norte Centro Histórico de la ciudad de Barranquilla. MÉTODO: Estudio descriptivo de corte transversal realizado en 755 estudiantes de cuatro a ocho años de edad de colegios oficiales y privados. El perfil motriz se midió mediante la Batería Psicomotora (BPM) de Da Fonseca. RESULTADOS: Existe mayor riesgo para un desempeño apráxico-dispráxico del subfactor praxia global para los escolares de cuatro a cinco años [OR 4,8; IC 95 %; 3,3-7,1] que estudian en colegios oficiales [OR 4,4; IC 95 %; 2,7-7,3]; los que viven en estrato 1, 2 y 3 [OR 2,4; IC 95 %; 1,5-3,9] y quienes tienen un peso aumentado [OR 2; IC 95 %; 1,2-3,3]. El mayor riesgo para un desempeño apráxico-dispráxico en praxia fina fue los participantes de cuatro a cinco años de edad [OR 3,7; IC 95 %; 2,7-5,3], para los estudiantes de colegios oficiales [OR 1,9; IC 95 %; 1,3-2,]. Un desempeño apráxico-dispráxico en el subfactor estructuración espacio temporal es mayor en las niñas [OR 1,6; IC 95 %; 1,12,2], para los escolares de cuatro a cinco [OR 4,8; IC 95 %; 3,3-7,1]; en los que estudian en el sector oficial [OR 1,9; IC 95 %; 2,7-5,3]; para los que residen en estratos socioeconómicos 1, 2 y 3 [OR 1,6; IC 95 %; 1,1-2,7]. CONCLUSIONES: Los determinantes como estudiar en colegios del sector oficial, estado nutricional, género y estrato socioeconómico están relacionados con el desempeño motor de los estudiantes.


Asunto(s)
Apraxias/epidemiología , Desempeño Psicomotor , Apraxias/diagnóstico , Apraxias/etiología , Niño , Preescolar , Colombia/epidemiología , Estudios Transversales , Femenino , Humanos , Masculino , Estado Nutricional , Prevalencia , Factores de Riesgo , Factores Sexuales , Factores Socioeconómicos
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