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Int Rev Neurobiol ; 177: 1-9, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-39029980

RESUMEN

Cannabidiol (CBD) is one of over 200 cannabinoids present in the Cannabis plant. Unlike the plant's primary cannabinoid, delta-9-tetrahydrocannabinol (THC), CBD does not produce psychotomimetic effects nor induce dependence. Initially considered an inactive cannabinoid, interest in its pharmacological properties and therapeutic potential has grown exponentially over the last 20 years. Currently employed as a medication for certain epileptic syndromes, numerous pre-clinical and clinical studies support its potential use in various other disorders. In this chapter, we provide a brief historical overview of how this compound evolved from an "inactive substance" to a multifunctional clinical agent. Additionally, we discuss the current challenges in researching its potential therapeutic effects.


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Cannabidiol , Cannabidiol/uso terapéutico , Cannabidiol/farmacología , Cannabidiol/historia , Humanos , Historia del Siglo XX , Historia del Siglo XXI , Animales , Anticonvulsivantes/historia , Anticonvulsivantes/uso terapéutico , Anticonvulsivantes/farmacología , Historia del Siglo XIX
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