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1.
Am J Emerg Med ; 39: 252.e1-252.e2, 2021 01.
Artículo en Inglés | MEDLINE | ID: mdl-33008704

RESUMEN

We report a case of a 67-year-old Chinese man admitted to the emergency department for a persistent bleed on the tongue. Initial digital pressure and application of topical tranexamic acid did not stop the bleeding. An improvised clamp applied to the tongue was successful in achieving haemostasis. Using this method, there was no need for a clinical staff to be present for manual application of pressure. This frees up the staff for other clinical duties and matters.


Asunto(s)
Hemorragia/terapia , Técnicas Hemostáticas/instrumentación , Enfermedades de la Lengua/terapia , Lengua/lesiones , Anciano , Hemorragia/etiología , Humanos , Masculino , Enfermedades de la Lengua/etiología
3.
Bull Cancer ; 107(12S): S122-S129, 2020 Dec.
Artículo en Francés | MEDLINE | ID: mdl-32532421

RESUMEN

Stomatological complications of allogeneic hematopoietic stem cell transplantation (HSCT) are frequent and very uncomfortable for patients. The primary complication is the graft versus host disease reaction. Other side effects of the procedure include infections, taste disorders and carcinogenic risks. Various local treatments are used but remain imperfect. Within the framework of the 10th workshop of practice harmonization of the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC) held in Lille in September 2019, diagnostic approaches and treatments of tongue and oral complications following allogeneic HSCT were reviewed according to the analysis of published studies.


Asunto(s)
Trasplante de Células Madre Hematopoyéticas/efectos adversos , Enfermedades de la Boca/etiología , Enfermedad Aguda , Candidiasis Bucal/diagnóstico , Candidiasis Bucal/etiología , Candidiasis Bucal/terapia , Carcinoma de Células Escamosas/etiología , Enfermedad Crónica , Caries Dental/etiología , Caries Dental/prevención & control , Gota/etiología , Enfermedad Injerto contra Huésped/complicaciones , Humanos , Enfermedades de la Boca/diagnóstico , Enfermedades de la Boca/terapia , Neoplasias de la Boca/etiología , Enfermedades Periodontales/etiología , Sociedades Médicas , Enfermedades de la Lengua/diagnóstico , Enfermedades de la Lengua/etiología , Enfermedades de la Lengua/terapia , Acondicionamiento Pretrasplante/efectos adversos , Trasplante Homólogo/efectos adversos
4.
J Neurosurg ; 134(3): 1271-1275, 2020 Apr 24.
Artículo en Inglés | MEDLINE | ID: mdl-32330885

RESUMEN

Acute injury of the trigeminal nerve or its branches can result in posttraumatic trigeminal neuropathy (PTTN). Affected patients suffer from chronic debilitating symptoms long after they have recovered from the inciting trauma. Symptoms vary but usually consist of paresthesia, allodynia, dysesthesia, hyperalgesia, or a combination of these symptoms. PTTN of the trigeminal nerve can result from a variety of traumas, including iatrogenic injury from various dental and maxillofacial procedures. Treatments include medications, pulsed radiofrequency modulation, and microsurgical repair. Although trigeminal nerve stimulation has been reported for trigeminal neuropathy, V3 implantation is often avoided because of an elevated migration risk secondary to mandibular motion, and lingual nerve implantation has not been documented. Here, the authors report on a patient who suffered from refractory PTTN despite multiple alternative treatments. He elected to undergo novel placement of a lingual nerve stimulator for neuromodulation therapy. To the best of the authors' knowledge, this is the first documented case of lingual nerve stimulator implantation for lingual neuropathy, a technique for potentially reducing the risk of electrode migration.


Asunto(s)
Terapia por Estimulación Eléctrica/métodos , Nervio Lingual , Traumatismos del Nervio Trigémino/terapia , Resistencia a Medicamentos , Humanos , Traumatismos del Nervio Lingual/terapia , Masculino , Persona de Mediana Edad , Procedimientos Neuroquirúrgicos/métodos , Dolor/etiología , Manejo del Dolor , Enfermedades de la Lengua/etiología , Enfermedades de la Lengua/terapia , Resultado del Tratamiento , Enfermedades del Nervio Trigémino
5.
Probiotics Antimicrob Proteins ; 12(4): 1321-1329, 2020 12.
Artículo en Inglés | MEDLINE | ID: mdl-32227309

RESUMEN

This study was to evaluate the effect of Streptococcus salivarius K12 on tongue coating-associated halitosis. Twenty-eight subjects having tongue coating-associated halitosis were randomly divided into either a test or control group. For each of the 30 days, the test subjects sucked S. salivarius K12 tablet while the control subjects sucked placebo tablets. All the subjects did not take physical (tongue scraping) and chemical (antiseptic mouth-rinse) oral cavity pretreatment prior to use of the tablets. At baseline, and on the 1st, 7th, and 14th day after completing the course of tablets, the subjects were assessed for their organoleptic test (OLT) scores, volatile sulfur compound (VSC) levels, and tongue coating scores (TCS). During the course, all subjects kept their routine oral care habits without scraping their tongue coating. Plaque index, probing depth, and bleeding index were recorded at baseline and at the completion of the trial. On the 1st day following the end of tablet use, the OLT scores and VSC levels had significantly decreased in the test group when compared with the baseline values (P = 0.001 and P = 0.012). The TCS in the test group were also significantly decreased (P = 0.05). At days 7 and 14, the OLT scores in the test group were still significantly lower than the baseline levels (P = 0.006 and P = 0.039 respectively). However, there were no statistical differences with OLT, VSC, and TCS between the test group and the placebo group by analysis of multi-level regression model. The use of S. salivarius K12 did not have significant effect on halitosis with tongue coating cause when the tongue coating was not physically or chemically pre-treated, which implies removing tongue coating is required before Streptococcus salivarius K12 use.


Asunto(s)
Halitosis/terapia , Probióticos/uso terapéutico , Streptococcus salivarius/fisiología , Enfermedades de la Lengua/terapia , Administración Oral , Adulto , Método Doble Ciego , Femenino , Halitosis/fisiopatología , Humanos , Masculino , Compuestos de Azufre/análisis , Compuestos de Azufre/metabolismo , Comprimidos/administración & dosificación , Lengua/efectos de los fármacos , Enfermedades de la Lengua/fisiopatología
9.
Zhonghua Kou Qiang Yi Xue Za Zhi ; 54(5): 303-308, 2019 May 09.
Artículo en Chino | MEDLINE | ID: mdl-31091562

RESUMEN

Objective: To explore the clinical classification of microcystic lymphatic malformations of tongue and observe the treatment of microcystic lymphatic malformations of tongue by retrospective analysis, in order to provide reference for clinical practice. Methods: From October 2005 to October 2015, the complete data of 220 cases of microcystic lymphatic malformations of tongue (115 males and 105 females) received and treated in Provincial Special Department of Vascular Anomalies, Linyi Tumor Hospital was analyzed retrospectively. The age ranged from 8 months to 52 years old, with a median age of 16 years old. All patients were followed up for 3 years, and according to their clinical manifestations, they were divided into three types: localized type of 23 cases, diffuse type of 161 cases, and megaloglossia type of 36 cases. Injection with pingyangmycin merely was performed on 58 cases, whereas merely surgery on 20 cases, injection with pingyangmycin combined with high frequency electrocoagulation on 55 cases, and surgery combined with injection with pingyangmycin on 87 cases. The therapeutic effect was evaluated according to the grade 4 standard. The χ(2) test was used for statistical analysis of count data. Rank sum test was used for statistical analysis of ranked data. Results: The percentage of surgery merely of localized type was 87.0% (20/23), significantly higher than that of other types of lesions [0% (0/197)] (χ(2)=178.060, P<0.001). The percentage of injection with pingyangmycin of diffuse type was 100% (161/161), significantly higher than that of other types of lesions [66.1% (39/59)] (χ(2)=60.034, P<0.001). The percentage of surgery combined with injection with pingyangmycin of megaloglossia type was 100% (36/36), significantly higher than that of other types of lesions [27.7% (51/184)] (χ(2)=65.800, P<0.001). After follow-ups for 3 to13 years, there were 0 cases of gradeⅠ, 11 cases of grade Ⅱ, 50 cases of grade Ⅲ, and 159 cases of grade Ⅳ. There were statistically significant differences in clinical efficacy among different clinical types (H=158.668, P<0.001). The percentage of level Ⅳ efficacy of localized type, diffuse type and megaloglossia type were 100% (23/23), 82.6% (133/161) and 8.3% (3/36) respectively. Local mucosa ulcer appeared in 45 cases and was cured through oral care and expectant treatment. Fever occurred in 28 cases and returned to normal within 24 h after expectant treatment. The lingual frenum was shortened in 16 cases. There were 12 cases with mild tongue swelling, 6 cases with influence on eating but without influence on breathing, and recovered spontaneously one week later. Conclusions: The choice of different treatment methods of microcystic lymphatic malformations of tongue should be made according their clinical classification. The only surgical resection is recommended for localized protrude lesions. Injection with pingyangmycin in high tension combined with surgical resection or high frequency electrocoagulation is effective for diffuse lesions. Surgical resection combined with injection with pingyangmycin is suitable for the patients with megaloglossia type.


Asunto(s)
Quistes , Anomalías Linfáticas , Enfermedades de la Lengua , Adolescente , Bleomicina , Femenino , Humanos , Anomalías Linfáticas/diagnóstico , Anomalías Linfáticas/terapia , Masculino , Estudios Retrospectivos , Lengua , Enfermedades de la Lengua/diagnóstico , Enfermedades de la Lengua/terapia , Resultado del Tratamiento
11.
Int J Hematol ; 108(6): 615-621, 2018 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-30144000

RESUMEN

Graft-versus-host disease (GvHD) causes severe mucositis, impairs feeding and favors infection. The objective of this study was to identify the impact of GvHD in the oral cavity. We reviewed all consecutive patients who developed oral GvHD after HSCT. The study period was over 14 years. 53 patients were identified. M/F = 1.4; median age was 48.6 years; the median follow-up was for up to 3 years and 6 months. Conditioning regimens included several drugs (e.g., busulfan, cyclophosphamide and fludarabine). In 11 cases, radiotherapy (RT) was also used. Patients treated with RT were more likely to have tooth decay requiring fillings (p = 0.029), to need canal root interventions (p = 0.005) and to have tartar requiring oral hygiene interventions (p = 0.011). Patients with a lymphoma diagnosis were more likely to develop perioral scleroderma and chronic oral GvHD (cGvHD) (p = 0.045). Oral acute GvHD (aGvHD) was seen in 26 patients (49.1%). 21 (39.6%) patients developed cGvHD. GvHD of the tongue was seen in 21 (40%) patients. Oral mucositis was seen in only 5 patients (9.4%). Conditioning regimens with RT are more likely to induce oral aGvHD. The tongue is often affected by GvHD.


Asunto(s)
Enfermedad Injerto contra Huésped/diagnóstico , Enfermedad Injerto contra Huésped/etiología , Estomatitis/diagnóstico , Estomatitis/etiología , Enfermedades de la Lengua/diagnóstico , Enfermedades de la Lengua/etiología , Adulto , Anciano , Protocolos de Quimioterapia Combinada Antineoplásica/efectos adversos , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapéutico , Femenino , Enfermedad Injerto contra Huésped/prevención & control , Enfermedad Injerto contra Huésped/terapia , Trasplante de Células Madre Hematopoyéticas/efectos adversos , Humanos , Inmunosupresores/administración & dosificación , Inmunosupresores/uso terapéutico , Masculino , Persona de Mediana Edad , Higiene Bucal , Radioterapia/efectos adversos , Estudios Retrospectivos , Estomatitis/prevención & control , Estomatitis/terapia , Enfermedades de la Lengua/prevención & control , Enfermedades de la Lengua/terapia , Acondicionamiento Pretrasplante/efectos adversos , Trasplante Homólogo
12.
J Craniofac Surg ; 29(3): e243-e245, 2018 May.
Artículo en Inglés | MEDLINE | ID: mdl-29381642

RESUMEN

Tongue abscess is a serious clinical entity which scarcely affects the tongue. It should be treated urgently to prevent airway obstruction or dissemination of infection to a more deep or distant area of the body. This article presented the first clinical report of tongue abscess in Iraq which discussed its clinical presentation, diagnosis, and treatment with a review of literature.


Asunto(s)
Absceso , Enfermedades de la Lengua , Lengua/patología , Absceso/diagnóstico , Absceso/patología , Absceso/terapia , Biopsia con Aguja Fina , Femenino , Humanos , Irak , Persona de Mediana Edad , Enfermedades de la Lengua/diagnóstico , Enfermedades de la Lengua/patología , Enfermedades de la Lengua/terapia
13.
Swiss Dent J ; 127(10): 846-851, 2017 10 16.
Artículo en Inglés | MEDLINE | ID: mdl-29199412

RESUMEN

About every fourth individual suffers at leasttemporarily from oral malodor. The most frequentcause of it is the oral cavity, in particular thetongue coating. In professional halitosis clinics,findings and diagnoses are discussed with thepatients, and individual therapy concepts are designed. Currently, there are only few ev alua- tions of such clinics, which moreover are con- fined to a period of a few weeks or months. The aim of the present work was to evaluate the halitosis clinic of the University Center of Dental Medicine Basel o ver a period of eleven years. For the purpose of a recall, 638 patients w ere con- tacted, who had visited the halitosis clinic be- tween February 2003 and February 2014. Of these, 280 patients answ ered a special question- naire. The halitosis clinic was rated as helpf ul by 81.9% of the respondents. The majority (61.8%) only rarely or never suffered from bad breath anymore and still carried out the recommended tongue cleaning. Ninety-one patients who re- ported to suffer again from oral malodor, could be re-evaluated also clinically. The strictly cause- oriented therapy concept of the halitosis clinic of the Univ ersity Center of Dental Medicine Basel has proved successful over eleven years.


Asunto(s)
Instituciones de Atención Ambulatoria/normas , Halitosis/etiología , Halitosis/terapia , Facultades de Odontología , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Niño , Femenino , Humanos , Masculino , Persona de Mediana Edad , Higiene Bucal/normas , Satisfacción del Paciente , Garantía de la Calidad de Atención de Salud/normas , Encuestas y Cuestionarios , Suiza , Enfermedades de la Lengua/diagnóstico , Enfermedades de la Lengua/terapia , Adulto Joven
14.
Swiss Dent J ; 127(10): 846-851, 2017 10 16.
Artículo en Inglés | MEDLINE | ID: mdl-29199413

RESUMEN

About every fourth individual suffers at least temporarily from oral malodor. The most frequent cause of it is the oral cavity, in particular the tongue coating. In professional halitosis clinics, findings and diagnoses are discussed with the patients, and individual therapy concepts are designed. Currently, there are only few evaluations of such clinics, which moreover are confined to a period of a few weeks or months. The aim of the present work was to evaluate the halitosis clinic of the University Center of Dental Medicine Basel over a period of eleven years. For the purpose of a recall, 638 patients were contacted, who had visited the halitosis clinic between February 2003 and February 2014. Of these, 280 patients answered a special questionnaire. The halitosis clinic was rated as helpful by 81.9% of the respondents. The majority (61.8%) only rarely or never suffered from bad breath anymore and still carried out the recommended tongue cleaning. Ninety-one patients who reported to suffer again from oral malodor, could be re-evaluated also clinically. The strictly cause-oriented therapy concept of the halitosis clinic of the University Center of Dental Medicine Basel has proved successful over eleven years.


Asunto(s)
Halitosis , Enfermedades de la Lengua , Instituciones de Atención Ambulatoria , Halitosis/terapia , Humanos , Encuestas y Cuestionarios , Enfermedades de la Lengua/terapia
15.
Presse Med ; 46(9): 864-868, 2017 Sep.
Artículo en Francés | MEDLINE | ID: mdl-28687188

RESUMEN

Oral disorders were observed in children with congenital hypothyroidism, lately apparent because of difficulties of feeding, swallowing disorders, and macroglossia. Macroglossia was also a component of the severe acquired myxedema, particularly observed in hypothyroidism related to autoimmune atrophic thyroiditis beyond menopause. Lingual ectopy in children and adults could determine respiratory gene or swallowing difficulties, and were detectable by visual examination and the endobuccal touch. Expression of these events was completely minimized since the neonatal screening of congenital hypothyroidism, also by the common practice in adults of serum TSH determinations. Congenital and acquired hormonal deficits are now early detected and correct with suppletive doses of levothyroxine. Oral expression of hyperthyroidism is poor, even if thyrotoxicosis is sometimes revealed by increased thirst. Caution is required for dental care, mainly due to changes in the hemostatic functions. Finally, a genetic predisposition to the medullary thyroid cancer may be revealed by an oral and neuromatosis. Radioisotopic therapy of thyroid cancers is likely to alter the salivation.


Asunto(s)
Enfermedades de la Boca/diagnóstico , Enfermedades de la Tiroides/diagnóstico , Enfermedades Dentales/diagnóstico , Adulto , Niño , Coristoma/diagnóstico , Coristoma/genética , Coristoma/terapia , Terapia Combinada , Atención Odontológica , Humanos , Recién Nacido , Enfermedades de la Boca/etiología , Enfermedades de la Boca/terapia , Tamizaje Neonatal , Fenotipo , Enfermedades de la Tiroides/complicaciones , Enfermedades de la Tiroides/genética , Enfermedades de la Tiroides/terapia , Enfermedades de la Lengua/diagnóstico , Enfermedades de la Lengua/genética , Enfermedades de la Lengua/terapia , Enfermedades Dentales/etiología , Enfermedades Dentales/terapia
16.
Rehabil. integral (Impr.) ; 12(1): 8-12, jun. 2017. ilus
Artículo en Español | LILACS | ID: biblio-908003

RESUMEN

Male patient, 19 years old, diagnosed with severe mixed tetraparesis, predominantly spastic, secondary to severe perinatal asphyxia, West syndrome and intellectual disability, GMFCS V. october 2012 presents a 1 cm white-colored and painless ulcer on the ventral surface of the tongue, showing indurated borders, and no signs of palpable lymph nodes, compatible with Riga-Fede disease. the patient is referred to the commune hospital. August 2013 attends a dental control presenting the ulcer with similar conditions, awaiting treatment from the hospital. April 2014 he returns for a health control in the same conditions. this time a non invasive intervention is performed, covering the incisal edges of teeth 3.1 and 4.1 with composite resin. A two weeks later control shows a smaller ulceration. By June 2015 the ulcer has healed completely, and stayed healed until january 2016. the mother reports decreased tongue protrusion in frequency and intensity since January 2015. Conclusion: Sublingual traumatic ulcer can be healed by eliminating the cause of the trauma, using a non invasive technique.


Paciente de sexo masculino, 19 años de edad con diagnóstico de tetraparesia mixta severa de predominio espástico, secundaria a asfixia perinatal, síndrome de West y discapacidad intelectual, GMFCS V. En octubre de 2012 presenta úlcera en cara ventral de la lengua, de 1 cm de diámetro aproximadamente, de bordes indurados, fondo de color blanquecino e indolora, sin ganglios palpables, compatible con diagnóstico de enfermedad de Riga Fede. Se deriva en esa oportunidad al hospital de su comuna. En agosto de 2013 asiste nuevamente a control presentando la úlcera con similares condiciones, en espera de tratamiento en el hospital. En abril de 2014 vuelve a control en iguales condiciones. En esta oportunidad se realiza intervención no invasiva, recubriendo superficies incisales de dientes 3,1 y 4,1 con resina compuesta. En control a las dos semanas se observa la úlcera más pequeña. En junio de 2014 se observa ausencia de úlcera, situación que persiste hasta control de enero de 2016. La madre manifiesta que protrusión lingual ha disminuido en frecuencia e intensidad desde enero de 2015. Conclusión: La úlcera sublingual de origen traumático puede ser resuelta eliminando la causa del trauma, de forma no invasiva.


Asunto(s)
Masculino , Humanos , Adulto Joven , Parálisis Cerebral/complicaciones , Úlceras Bucales/terapia , Enfermedades de la Lengua/terapia , Úlceras Bucales/etiología , Enfermedades de la Lengua/etiología
17.
Pediatr Infect Dis J ; 36(7): 694-695, 2017 07.
Artículo en Inglés | MEDLINE | ID: mdl-28030529

RESUMEN

We report the case of a 14-month-old boy who developed a swelling of the tongue with fever, dyspnea during sleep and dysphagia. An anterior lingual abscess was identified by magnetic resonance imaging. He developed 4 recurrent lingual abscesses thereafter. Pediatricians should be aware of this problem because it can be a life-threatening condition.


Asunto(s)
Absceso , Enfermedades de la Lengua , Lengua , Absceso/diagnóstico por imagen , Absceso/patología , Absceso/terapia , Humanos , Lactante , Imagen por Resonancia Magnética , Masculino , Recurrencia , Lengua/diagnóstico por imagen , Lengua/patología , Enfermedades de la Lengua/diagnóstico por imagen , Enfermedades de la Lengua/patología , Enfermedades de la Lengua/terapia
19.
Int J Pediatr Otorhinolaryngol ; 89: 13-6, 2016 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-27619021

RESUMEN

OBJECTIVES/HYPOTHESIS: To determine the epidemiology of incidental thyroglossal duct cysts (TGDC) discovered on imaging studies obtained in the head and neck area in children and to discuss subsequent management. METHODS: A retrospective chart review was performed at Texas Children's Hospital of all computed tomography (CT) and magnetic resonance (MR) imaging studies obtained in the head and neck region between July 2011 and July 2014. Images obtained for the purpose of evaluating a neck or lingual mass were excluded from the study, as were patients with previously known TGDCs. Data including age, sex, location of TGDC, size, presence of symptoms, referral to Otolaryngology, and intervention were recorded. RESULTS: A total of 60,663 CT and MR studies of the head, brain, sinus, neck, and C-spine during this time period were reviewed; of these 69 (0.1%) cases contained incidental discovery of probable TGDCs with more males (40) than females (29). Ages ranged from 3 days to 17 years old, with the mean age at 5 years. Locations varied, with majority at base of tongue (83%) followed by hyoid (13%) then infrahyoid straps (4%). Sizes ranged from 2 to 28 mm with average size at 8 mm. 11 of these patients were referred to an Otolaryngologist; 9 were asymptomatic and decision was made to observe, the other two subsequently underwent surgical excision secondary to mass effect and dysphagia with histologic confirmation of diagnosis. CONCLUSION: TGDCs commonly present as an anterior neck mass, however the majority of incidentally discovered TGDCs on imaging are located at the base of tongue. Management of these findings should include referral to an Otolaryngologist for further evaluation with the decision to intervene surgically based on development of clinical symptoms.


Asunto(s)
Hallazgos Incidentales , Quiste Tirogloso/epidemiología , Enfermedades de la Lengua/epidemiología , Adolescente , Niño , Preescolar , Trastornos de Deglución/etiología , Trastornos de Deglución/cirugía , Manejo de la Enfermedad , Femenino , Humanos , Hueso Hioides/diagnóstico por imagen , Lactante , Recién Nacido , Imagen por Resonancia Magnética , Masculino , Otolaringología , Prevalencia , Derivación y Consulta , Estudios Retrospectivos , Texas/epidemiología , Quiste Tirogloso/complicaciones , Quiste Tirogloso/diagnóstico por imagen , Quiste Tirogloso/terapia , Tomografía Computarizada por Rayos X , Enfermedades de la Lengua/complicaciones , Enfermedades de la Lengua/diagnóstico por imagen , Enfermedades de la Lengua/terapia
20.
Gen Dent ; 64(5): 25-9, 2016.
Artículo en Inglés | MEDLINE | ID: mdl-27599277

RESUMEN

Vascular anomalies such as hemangiomas or vascular malformations can produce negative esthetic effects in the maxillofacial region. These negative effects are the main complaints of patients. The clinical therapeutic efficacy of cryotherapy and sclerotherapy in the treatment of these lesions was evaluated in 10 patients who were clinically diagnosed with vascular lesions. Lesions were submitted to either cryotherapy or sclerotherapy, and follow-up showed that cryotherapy and sclerotherapy both were clinically effective in treating oral vascular lesions. Cryotherapy is an easy to perform method that requires only 1 session, but the high cost of the equipment is a limiting factor. Sclerotherapy is a noninvasive treatment widely accepted by patients, but more than 1 session is required.


Asunto(s)
Crioterapia/métodos , Enfermedades de la Boca/terapia , Escleroterapia/métodos , Malformaciones Vasculares/terapia , Adolescente , Adulto , Anciano , Femenino , Hemangioma/terapia , Humanos , Enfermedades de los Labios/terapia , Masculino , Persona de Mediana Edad , Neoplasias de la Boca/terapia , Enfermedades de la Lengua/terapia
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