RESUMEN
PURPOSE: Echinococcosis, also known as hydatidosis, is a zoonosis that is endemic in many countries worldwide. Liver hydatid cysts have a wide variety of clinical manifestations, among which obstructive jaundice is one of the rarer forms. The aims of the study were to analyze the preoperative management of these patients and to record the kind of surgical treatment performed and the short- and long-term postoperative results. METHODS: A retrospective two-center observational study of patients operated upon for liver hydatidosis with initial symptoms of obstructive jaundice. Preoperative characteristics, surgical data, and postoperative complications, including biliary fistula, were recorded. RESULTS: Of 353 patients operated upon for liver hydatidosis, 44 were included in the study. Thirty-five patients (79.6%) were defined as CE2 or CE3 in the World Health Organization (WHO) classification. Preoperative endoscopic retrograde cholangiopancreatography (ERCP) was performed in 25 patients (56.8%) and identified intrabiliary communication in 29. Radical surgery was carried out in 29 of the total sample (65.9%). Severe postoperative complications (Clavien-Dindo grade IIIA or higher) were recorded in 25% of patients. The factors associated with greater postoperative morbidity were age above 65 (HR 8.76 [95% CI 0.78-97.85]), cyst location (HR 4.77 [95% CI 0.93-24.42]), multiple cysts (HR 14.58 [95% CI 1.42-149.96]), and cyst size greater than 5 cm (HR 6.88 [95% CI 0.95-50]). CONCLUSION: The presentation as obstructive jaundice causes greater postoperative morbidity. The main postoperative complication in these cases, despite radical surgery, is biliary fistula. In our series, routine preoperative ERCP did not show any benefit.
Asunto(s)
Fístula Biliar , Equinococosis , Ictericia , Fístula Biliar/epidemiología , Fístula Biliar/etiología , Fístula Biliar/cirugía , Colangiopancreatografia Retrógrada Endoscópica , Humanos , Hígado , Complicaciones Posoperatorias/epidemiología , Complicaciones Posoperatorias/etiología , Estudios RetrospectivosRESUMEN
Biliary fistulation from a hepatic hydatid cyst is its most frequent complication. If unrecognised, this may cause difficulties during and after surgical intervention. Our study looked into its incidence and also the possible risk factors in a retrospective investigation of 60 patients (34 women) who had undergone surgery or percutaneous treatment. Demographics and anatomical characteristics, such as cyst type, location, number, diameter and laboratory findings were examined. A full 50% had biliary fistulation, with increased risk if the cyst diameter was ≥8.8 cm.
Asunto(s)
Fístula Biliar/epidemiología , Enfermedades de las Vías Biliares/epidemiología , Equinococosis Hepática/cirugía , Adulto , Femenino , Humanos , Incidencia , Masculino , Estudios Retrospectivos , Factores de RiesgoRESUMEN
BACKGROUND: Biliary fistula (BF) is a major surgical complication that can develop after pancreaticoduodenectomy (PD) whose risk factors remain unclear. Substantial atherosclerotic celiac axis stenosis (SACAS) has not been reported to be one of them. METHODS: Data from 507 patients undergoing PD between Jan 1, 2013 and Dec 31, 2015 were retrospectively collected. Clinical data from patients with SACAS were studied, and the independent risk factors for BF underwent multivariate logistic regression analysis, including SACAS. RESULTS: BF occurred in 22 (4.3%) patients, and the incidence of BF was significantly higher in patients with SACAS than in those without it (27.0% vs 2.6%, Pâ¯<â¯.001). In the univariate analysis, BF was significantly related to SACAS, older age, a higher ASA score, history of coronary disease, greater blood loss and RBC transfusion during surgery, smaller CBD diameter and higher POD 1 BUN level. The multivariate analysis showed that only SACAS (OR 8.91, 95% CI 2.36-33.69, Pâ¯=â¯.001), older age (OR 1.08, 95% CI 1.01-1.15, Pâ¯=â¯.028) and smaller preoperative CBD (OR 0.79, 95% CI 0.69-0.92, Pâ¯=â¯.002) were independent risk factors for postoperative BF. CONCLUSION: Older age and a smaller preoperative CBD diameter are independent risk factors for BF after PD, which is consistent with the literature. In addition, SACAS is a new independent risk factor for BF. For patients with SACAS, postoperative drainage should be carefully managed to precisely observe the potential for BF.
Asunto(s)
Arteriosclerosis/complicaciones , Fístula Biliar/etiología , Arteria Celíaca/patología , Pancreaticoduodenectomía/efectos adversos , Complicaciones Posoperatorias/etiología , Factores de Edad , Anciano , Arteriosclerosis/patología , Fístula Biliar/epidemiología , Fístula Biliar/cirugía , Constricción Patológica/complicaciones , Bases de Datos Factuales , Drenaje/efectos adversos , Femenino , Humanos , Incidencia , Modelos Logísticos , Masculino , Persona de Mediana Edad , Análisis Multivariante , Complicaciones Posoperatorias/epidemiología , Complicaciones Posoperatorias/cirugía , Periodo Posoperatorio , Periodo Preoperatorio , Estudios Retrospectivos , Factores de RiesgoRESUMEN
INTRODUCTION: Bilioenteric fistulas are the abnormal communication between the bile duct system and the gastrointestinal tract that occurs spontaneously and is a rare complication of an untreated gallstone in the majority of cases. These fistulas can cause diverse clinical consequences and in some cases be life-threatening to the patient. AIM: To identify the incidence of bilioenteric fistula in patients with gallstones, its clinical presentation, diagnosis through imaging study, surgical management, postoperative complications, and follow-up. MATERIALS AND METHODS: A retrospective study was conducted to search for bilioenteric fistula in patients that underwent cholecystectomy at our hospital center due to cholelithiasis, cholecystitis, or cholangitis, within a 3-year time frame. RESULTS: Four patients, 2 men and 2 women, were identified with cholecystoduodenal fistula. Their mean age was 81.5 years. Two of the patients presented with acute cholangitis and 2 presented with bowel obstruction due to gallstone ileus. All the patients underwent surgical treatment and the diagnostic and therapeutic management of each of them was analyzed. CONCLUSIONS: The incidence of cholecystoduodenal fistula was similar to that reported in the medical literature. It is a rare complication of gallstones and its diagnosis is difficult due to its nonspecific symptomatology. It should be contemplated in elderly patients that have a contracted gallbladder with numerous adhesions.
Asunto(s)
Fístula Biliar/cirugía , Colecistectomía , Colelitiasis/complicaciones , Fístula Intestinal/cirugía , Anciano , Anciano de 80 o más Años , Fístula Biliar/diagnóstico , Fístula Biliar/epidemiología , Fístula Biliar/etiología , Femenino , Estudios de Seguimiento , Humanos , Incidencia , Fístula Intestinal/diagnóstico , Fístula Intestinal/epidemiología , Fístula Intestinal/etiología , Masculino , Estudios Retrospectivos , Resultado del TratamientoRESUMEN
Biliary leakage (BL) is the most common cause of postoperative morbidity after conservative liver hydatid cyst surgery. The objective of this study was to determine incidence of BL and related risk factors in patients with solitary liver hydatid cyst who underwent conservative surgery. A total of 186 patients were included in this study. Age, gender, cyst recurrence, diameter, and localization, World Health Organization Informal Working Group on Echinococcosis (WHO-IWGE) classification, cavity management techniques, cyst content, and alkaline phosphatase (ALP) levels were evaluated with univariate and multivariate analyses. Of these patients 104 were female and 82 were male. The mean age was 43.5 ± 14.7 years. Postoperative BL was detected in 36 (19.4%) patients. Cyst diameter (P = 0.019), cyst localization (P = 0.007), WHO-IWGE classification (P = 0.017), and ALP level (P = 0.001) were the most significant risk factors for BL. Independent risk factors for BL were perihilar localization, large cyst diameter, high ALP level, and advanced age according to WHO-IWGE classification.
Asunto(s)
Fístula Biliar/etiología , Equinococosis Hepática/cirugía , Complicaciones Posoperatorias/etiología , Adulto , Factores de Edad , Fosfatasa Alcalina/sangre , Análisis de Varianza , Antihelmínticos/administración & dosificación , Fístula Biliar/epidemiología , Equinococosis Hepática/patología , Femenino , Humanos , Incidencia , Masculino , Persona de Mediana Edad , Recurrencia , Factores de RiesgoRESUMEN
BACKGROUND: Biliary fistula (BF) occurs in 3-8% of patients following pancreaticoduodenectomy (PD). It usually pursues a benign course, but rarely may represent a life-threatening event. STUDY DESIGN: Data from 1618 PDs were collected prospectively. BF was defined as the presence of bile stained fluid from drains by post-operative day 3 and confirmed by sinogram in the majority of cases. Three classifications were validated. RESULTS: BF occurred in 58 (3.6%) patients. In 22 cases was associated with pancreatic fistula (POPF). POPF, PPH, operative time and a smaller common bile duct (CBD) were significantly associated with BF. Only CBD diameter (HR 0.55, CI 95% 0.44-0.7, p < 0.01) was an independent predictor of BF. Patients with smaller CBDs developing concomitant BF and POPF carried the highest mortality rate (34.8%, n = 8/22). All the existing classifications resulted in discrete categories of BFs when considering hospital stay and total cost as dependent variables. CONCLUSIONS: Biliary fistula is rare, but it can be life threatening when associated with POPF. As the sole independent risk factor is the CBD diameter, surgical technique is crucial. Regardless of the existing classification systems, further studies must assess the additive burden of BF when a concomitant POPF is present.
Asunto(s)
Fístula Biliar/epidemiología , Pancreaticoduodenectomía/efectos adversos , Anciano , Fístula Biliar/diagnóstico , Fístula Biliar/mortalidad , Bases de Datos Factuales , Drenaje , Femenino , Hospitales de Alto Volumen , Humanos , Incidencia , Italia/epidemiología , Masculino , Persona de Mediana Edad , Pancreaticoduodenectomía/mortalidad , Estudios Prospectivos , Factores de Riesgo , Factores de Tiempo , Resultado del TratamientoRESUMEN
BACKGROUND: LPD has been cautiously regarded as feasible and safe for resection and reconstruction. However, anastomosis of the remnant pancreas is still thought to be a critical obstacle to the dissemination of LPD in general practice. This study presents a new technique of pancreaticojejunostomy for nondilated pancreatic duct and evaluates its safety and reliability. METHODS: From July 2014 to June 2015, a total of 52 patients underwent LPD with the new technique. A modified technique of duct-to-mucosa PJ was performed with transpancreatic interlocking mattress sutures, named the imbedding duct-to-mucosa PJ. Then the morbidity and mortality was calculated. RESULTS: This technique was applied in 52 patients after LPD all with nondilated pancreatic duct (1-3 mm). The mean operation time was 4.6 h (range, 3.5-8.3 h) and the median time for the anastomosis was 37 min (range, 24-53 min). Operative mortality was zero, and morbidity was 21.2 % (n = 11), including hemorrhage (n = 3, 5.8 %), biliary fistula (n = 1, 1.9 %), pulmonary infection (n = 1, 1.9 %), delayed gastric emptying (n = 2, 3.8 %), abdominal abscess caused by biliary fistula or PF formation (n = 2, 3.8 %), and POPF (n = 2, 3.8 %). Two patients developed a pancreatic fistula (one type A, one type B) classified according to the International Study Group on Pancreatic Fistula. CONCLUSIONS: The described technique is a simple and safe reconstruction procedure after LPD, especially for patients with nondilated pancreatic duct.
Asunto(s)
Adenocarcinoma/cirugía , Fístula Biliar/epidemiología , Neoplasias Duodenales/cirugía , Conductos Pancreáticos/cirugía , Fístula Pancreática/epidemiología , Neoplasias Pancreáticas/cirugía , Pancreaticoduodenectomía/métodos , Pancreatoyeyunostomía/métodos , Hemorragia Posoperatoria/epidemiología , Absceso Abdominal/epidemiología , Adulto , Anciano , Ampolla Hepatopancreática , Anastomosis Quirúrgica/métodos , Neoplasias de los Conductos Biliares/cirugía , Enfermedad de Crohn/cirugía , Cistoadenoma Mucinoso/cirugía , Femenino , Tumores del Estroma Gastrointestinal/cirugía , Gastroparesia/epidemiología , Humanos , Laparoscopía/métodos , Linfoma/cirugía , Masculino , Persona de Mediana Edad , Tempo Operativo , Páncreas/cirugía , Complicaciones Posoperatorias/epidemiología , Reproducibilidad de los Resultados , Técnicas de Sutura , SuturasRESUMEN
BACKGROUNDË Despite notable advances in surgical skills and technology, incidence of biliary fistula after hepatic resection remains an issue. Aim of this study was to assess the role of intraoperative perihepatic drain in diagnosis and treatment of this complication. METHODSË The study included 641 patients who underwent hepatic resection without hepaticojejunostomy between Jan-2003 and Jan-2016. Data were obtained from our single-institution perspective database. RESULTSË Biliary fistula occurred in 3.4% (22/641). Major hepatic resection (P<0.001), S4-involving resection (P=0.006), cholangiocarcinoma (P<0.001) and intraoperative blood losses >375 mL (P<0.001) were associated with biliary fistula. At multivariate analysis, among patients with effective intraoperative perihepatic drain ("D" group) (16/22) onset of biliary fistula (mean, 5.1 vs. 31.5 days, P=0.12) and healing time (mean, 26.5 vs. 82.3 days, P=0.033) were more favorable compared with biloma group (B). Moreover, conservative treatment was more effective in D group (75% of cases). B group developed increased morbidity in terms of jaundice (83.3% vs. 18.7%, P=0.005), abscess (66.7% vs. 6.2%, P=0.003) and a trend of prolonged hospital stay (mean, 25.7 vs. 19.2 days, P=0.51) and mortality (16.7% vs. 6.2%, P=0.449). Difference in biliary fistula severity rate according to ISGLS classification between the two groups was statistically significant (P=0.003). CONCLUSIONSË This study confirms that the wider is the resection the higher the risk for biliary fistula. A correct drainage of bile leakage is the crucial requisite for early healing, providing a milder postoperative course. In our experience, intraoperative perihepatic drain positioning plays a key-role, as well as postoperative patency monitoring.
Asunto(s)
Fístula Biliar/etiología , Drenaje/métodos , Hepatectomía , Cuidados Intraoperatorios/métodos , Complicaciones Posoperatorias/etiología , Anciano , Neoplasias de los Conductos Biliares/cirugía , Fístula Biliar/epidemiología , Fístula Biliar/prevención & control , Pérdida de Sangre Quirúrgica , Colangiocarcinoma/cirugía , Colangiopancreatografia Retrógrada Endoscópica , Tratamiento Conservador , Femenino , Humanos , Cuidados Intraoperatorios/instrumentación , Ictericia/epidemiología , Ictericia/etiología , Tiempo de Internación/estadística & datos numéricos , Absceso Hepático/epidemiología , Absceso Hepático/etiología , Hepatopatías/cirugía , Masculino , Persona de Mediana Edad , Complicaciones Posoperatorias/epidemiología , Complicaciones Posoperatorias/prevención & control , Complicaciones Posoperatorias/terapia , Estudios Prospectivos , RiesgoRESUMEN
BACKGROUND: The incidence of bile duct injuries (BDI) after cholecystectomy, which is a life-threatening condition that has several medical and legal implications, currently stands at about 0.6%. The aim of this study is to describe our experience as the first center to use a laparoscopic approach for BDI repair. METHODS: A prospective study between June 2012 and September 2014 was developed. Twenty-nine consecutive patients with BDI secondary to cholecystectomy were included. Demographics, comorbidities, presenting symptoms, details of index surgery, type of lesion, preoperative and postoperative diagnostic work-up, and therapeutic interventions were registered. Videos and details of laparoscopic hepaticojejunostomy (LHJ) were recorded. Injuries were staged using Strasberg classification. A side-to-side anastomosis with Roux-en-Y reconstruction was always used. In patients with E4 and some E3 injuries, a segment 4b or 5 section was done to build a wide anastomosis. In E4 injuries, a neo-confluence was performed. Complications, mortality, and long-term evolution were recorded. RESULTS: Twenty-nine patients with BDI were operated. Women represented 82.7% of the cases. The median age was 42 years (range 21-74). Injuries at or above the confluence occurred in 62%, and primary repair at our institution was performed at 93.1% of the cases. Eight neo-confluences were performed in all E4 injuries (27.5%). The median operative time was 240 min (range 120-585) and bleeding 200 mL (range 50-1100). Oral intake was started in the first 48 h. Bile leak occurred in 5 cases (17.2%). Two patients required re-intervention (6.8%). No mortality was recorded. The maximum follow-up was 36 months (range 2-36). One patient with E4 injury developed a hepaticojejunostomy (HJ) stenosis after 15 months. This was solved with endoscopic dilatation. CONCLUSIONS: The benefits of minimally invasive approaches in BDI seem to be feasible and safe, even when this is a complex and catastrophic scenario.
Asunto(s)
Conductos Biliares/lesiones , Fístula Biliar/epidemiología , Colecistectomía Laparoscópica/efectos adversos , Complicaciones Posoperatorias/epidemiología , Adulto , Anciano , Anastomosis en-Y de Roux , Conductos Biliares/cirugía , Fístula Biliar/etiología , Fístula Biliar/cirugía , Femenino , Humanos , Masculino , México/epidemiología , Persona de Mediana Edad , Complicaciones Posoperatorias/etiología , Complicaciones Posoperatorias/cirugía , Estudios Prospectivos , Reoperación , Estudios Retrospectivos , Factores de Riesgo , Resultado del Tratamiento , Adulto JovenRESUMEN
BACKGROUND: The International Study Group of Liver Surgery (ISGLS) defined posthepatectomy liver failure as pathological values for the international normalized ratio (INR) and bilirubin 5 days after liver resection. The occurrence of biliary leakage was defined as a drainage bilirubin to serum bilirubin ratio > 3 at day 3 or later after resection or interventional surgical revision due to biliary peritonitis. A confirmatory explorative analysis was carried out. PATIENTS AND METHODS: The study involved an evaluation of primary liver resection from the years 2009 and 2010. Primary endpoints were the incidence of posthepatectomy liver failure and biliary leakage in accordance with the ISGLS definition. Secondary endpoints were complications and 90-day mortality. Results are displayed as median values (minimum and maximum). RESULTS: A total of 214 liver resections were included from the years 2009 and 2010. Patients were an average of 61.5 years old (min. 18, max. 83 years). The incidence of liver failure was 7.4 % (16 out of 214) and fatal in 7 patients. In 31 % (65 out of 214) a biliary leakage occurred, 14 (23 %) patients developed a type B, 1 patient(5 %) a type C leakage and 50 leakages were clinically inapparent. The incidence of clinically relevant biliary leakages was 7 % (15 out of 214). The sensitivity of the definition was 100 % and the specificity 75 %. The incidence of Dindo-Calvien complications > 3b was 10.2 %, of sepsis 5.6 % and the 90-day mortality was 6.5 %. Multivariate analysis did not reveal independent predictive factors for biliary leakage or liver failure. CONCLUSION: The definition for posthepatectomy liver failure was found to be valid in this cohort. The incidence of postoperative biliary leakage is over-estimated with the current definition and delivers a large number of false positive results without clinical relevance.
Asunto(s)
Fístula Biliar/epidemiología , Hepatectomía/métodos , Fallo Hepático/epidemiología , Complicaciones Posoperatorias/epidemiología , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Fístula Biliar/etiología , Fístula Biliar/mortalidad , Bilirrubina/sangre , Estudios Transversales , Femenino , Estudios de Seguimiento , Humanos , Incidencia , Relación Normalizada Internacional , Fallo Hepático/etiología , Fallo Hepático/mortalidad , Masculino , Persona de Mediana Edad , Complicaciones Posoperatorias/etiología , Complicaciones Posoperatorias/mortalidad , Análisis de Supervivencia , Adulto JovenRESUMEN
INTRODUCTION: Gallstone ileus is a mechanical bowel obstruction caused by a biliary calculus originating from a bilioenteric fistula. Because of the limited number of reported cases, the optimal surgical method of treatment has been the subject of ongoing debate. METHODS: A retrospective review of the Nationwide Inpatient Sample from 2004 to 2009 was performed for gallstone ileus cases treated surgically by enterotomy with stone extraction alone (ES), enterotomy and cholecystectomy with fistula closure (EF), bowel resection alone (BR), and bowel resection with fistula closure (BF). Patient demographics, hospital factors, comorbidities, and postoperative outcomes were reported. Multivariate analysis was performed comparing mortality, morbidity, length of stay, and total cost for the different procedure types. RESULTS: Of the estimated 3,452,536 cases of mechanical bowel obstruction from 2004 to 2009, 3268 (0.095%) were due to gallstone ileus-an incidence lower than previously reported. The majority of patients were elderly women (>70%). ES was the most commonly performed procedure (62% of patients) followed by EF (19% of cases). In 19%, a bowel resection was required. The most common complication was acute renal failure (30.44% of cases). In-hospital mortality was 6.67%. On multivariate analysis, EF and BR were independently associated with higher mortality than ES [(odds ratio [OR] = 2.86; confidence interval [CI]: 1.16-7.07) and (OR = 2.96; CI: 1.26-6.96) respectively]. BR was also associated with a higher complication rate, OR = 1.98 (CI: 1.13-3.46). CONCLUSIONS: Gallstone ileus is a rare surgical disease affecting mainly the elderly female population. Mortality rates appear to be lower than previously reported in the literature. Enterotomy with stone extraction alone appears to be associated with better outcomes than more invasive techniques.
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Fístula Biliar/complicaciones , Procedimientos Quirúrgicos del Sistema Digestivo/tendencias , Cálculos Biliares/complicaciones , Fístula Intestinal/complicaciones , Obstrucción Intestinal/cirugía , Intestino Delgado/cirugía , Anciano , Anciano de 80 o más Años , Fístula Biliar/epidemiología , Fístula Biliar/mortalidad , Fístula Biliar/cirugía , Colecistectomía/estadística & datos numéricos , Colecistectomía/tendencias , Bases de Datos Factuales , Procedimientos Quirúrgicos del Sistema Digestivo/métodos , Procedimientos Quirúrgicos del Sistema Digestivo/estadística & datos numéricos , Femenino , Cálculos Biliares/epidemiología , Cálculos Biliares/mortalidad , Cálculos Biliares/cirugía , Mortalidad Hospitalaria , Humanos , Incidencia , Fístula Intestinal/epidemiología , Fístula Intestinal/mortalidad , Fístula Intestinal/cirugía , Obstrucción Intestinal/epidemiología , Obstrucción Intestinal/etiología , Obstrucción Intestinal/mortalidad , Modelos Logísticos , Masculino , Análisis Multivariante , Complicaciones Posoperatorias/epidemiología , Estudios Retrospectivos , Resultado del Tratamiento , Estados Unidos/epidemiologíaRESUMEN
AIM: To determine the outcome of patients with biliary fistula (BF) after treatment for hydatid disease of the liver. METHODS: Between January 2000 and December 2010, out of 301 patients with a diagnosis of hydatid cyst of the liver, 282 patients who underwent treatment [either surgery or puncture, aspiration, injection and reaspiration (PAIR) procedure] were analysed. Patients were grouped according to the presence or absence of postoperative biliary fistula (PBF) (PBF vs no-PBF groups, respectively). Preoperative clinical, radiological and laboratory characteristics, operative characteristics including type of surgery, peroperative detection of BF, postoperative drain output, morbidity, mortality and length of hospital stays of patients were compared amongst groups. Multivariate analysis was performed to detect factors predictive of PBF. Receiver operative characteristics (ROC) curve analysis were used to determine ideal cutoff values for those variables found to be significant. A comparison was also made between patients whose fistula closed spontaneously (CS) and those with intervention in order to find predictive factors associated with spontaneous closure. RESULTS: Among 282 patients [median (range) age, 23 (16-78) years; 77.0% male]; 210 (74.5%) were treated with conservative surgery, 33 (11.7%) radical surgery and 39 (13.8%) underwent percutaneous drainage with PAIR procedure A PBF developed in 46 (16.3%) patients, all within 5 d after operation. The maximum cyst diameter and preoperative alkaline phosphatase levels (U/L) were significantly higher in the PBF group than in the no-PBF group [10.5 ± 3.7 U/L vs 8.4 ± 3.5 U/L (P < 0.001) and 40.0 ± 235.1 U/L vs 190.0 ± 167.3 U/L (P = 0.02), respectively]. Hospitalization time was also significantly longer in the PBF group than in the no-PBF group [37.4 ± 18.0 d vs 22.4 ± 17.9 d (P < 0.001)]. A preoperative high alanine aminotransferase level (> 40 U/L) and a peroperative attempt for fistula closure were significant predictors of PBF development (P = 0.02, 95%CI: -0.03-0.5 and P = 0.001, 95%CI: 0.1-0.4), respectively. Comparison of patients whose PBF CS or with biliary intervention (BI) revealed that the mean diameter of the cyst was not significantly different between CS and BI groups however maximum drain output was significantly higher in the BI group (81.6 ± 118.1 cm vs 423.9 ± 298.4 cm, P < 0.001). Time for fistula closure was significantly higher in the BI group (10.1 ± 3.7 d vs 30.7 ± 15.1 d, P < 0.001). The ROC curve analysis revealed cut-off values of a maximum bilious drainage < 102 mL and a waiting period of 5.5 postoperative days for spontaneous closure with the sensitivity and specificity values of (83.3%-91.1%, AUC: 0.90) and (97%-91%, AUC: 0.95), respectively. The multivariate analysis demonstrated a PBF drainage volume < 102 mL to be the only statistically significant predictor of spontaneous closure (P < 0.001, 95%CI: 0.5-1.0). CONCLUSION: Patients with PBF after hydatid surgery often have complicated postoperative course with serious morbidity. Patients who develop PBF with an output < 102 mL might be managed expectantly.
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Enfermedades de los Conductos Biliares/epidemiología , Enfermedades de los Conductos Biliares/terapia , Fístula Biliar/epidemiología , Fístula Biliar/terapia , Equinococosis Hepática/cirugía , Adolescente , Adulto , Anciano , Manejo de la Enfermedad , Femenino , Humanos , Incidencia , Tiempo de Internación , Masculino , Persona de Mediana Edad , Análisis Multivariante , Estudios Retrospectivos , Tasa de Supervivencia , Resultado del Tratamiento , Adulto JovenRESUMEN
UNLABELLED: Cholecystectomy is one of the most performed surgical interventions in general surgery. Laparoscopic cholecystectomy was associated with an increasing occurrence of biliary ducts lesions. The aim of this study is to draw the attention towards the permanent risk of these kind of complications, the curative difficulties and identifying the best therapeutic solution in order to obtain favorable results on long term. METHOD: There were retrospectively and prospectively analysed all the cases with diagnosis of iatrogenic biliary ducts lesion hospitalized and operated during 1987-2008 in the Surgical Clinic No 3 Cluj Napoca. RESULTS: The yearly distribution showed an increasing number of biliary lesions operated in the Surgical Clinic No 3 Cluj-Napoca. 81% of the iatrogenic lesions in our study occurred postlaparoscopic cholecystectomy, and 19% secondary to an open cholecystectomy. One hundred thirty-six patients had major biliary lesions (D, E classes according to Strasberg Soper) and 47 patients had minor lesions (A-C classes). The medium hospitalization range was 17 days. Eighty - three patients (45.3%) needed one, two or three surgical interventions before the complete cure of the lesions. The most frequent complication was plague suppuration (12.5%). The cardio-renal-pulmonary complications were present in 8.7% of the patients and the intra-abdominal abscess in 3.8% of the patients. The anastomotic fistula was present in 11% of the operated patients and 6% global mortality. CONCLUSIONS: The iatrogenic lesions of the biliary ducts are characterized by a complicated evolution, with series of interventions and progressive evolution to biliary stenosis. Delaying the final biliary treatment and the high number of interventions performed before patients were referred to hepato-biliary specialised centres lead to an increasing morbidity and hospitalization costs.
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Conductos Biliares/lesiones , Fístula Biliar/etiología , Fístula Biliar/cirugía , Colecistectomía Laparoscópica/efectos adversos , Adulto , Anciano , Anciano de 80 o más Años , Anastomosis Quirúrgica/efectos adversos , Conductos Biliares/cirugía , Fístula Biliar/diagnóstico , Fístula Biliar/epidemiología , Colecistectomía/efectos adversos , Colecistectomía Laparoscópica/métodos , Femenino , Humanos , Incidencia , Tiempo de Internación , Masculino , Persona de Mediana Edad , Estudios Prospectivos , Reoperación , Estudios Retrospectivos , Rumanía/epidemiología , Tasa de SupervivenciaRESUMEN
BACKGROUND: For tumors deeply located in segment VIII (S8), right hepatectomy (RH) often is thought to solve the issue of technical accessibility. Yet, the common existence of an associated underlying diseased liver raises the question of parenchymal-sparing resection. METHODS: From 2002 to 2011, 34 patients underwent isolated S8 resection, and their operative and postoperative characteristics were compared to 34 matched patients who underwent RH for lesions located in S8. RESULTS: Indications and preoperative characteristics were comparable between the two groups except for larger tumors in RH patients compared with S8 patients (48 vs. 40 mm; p = 0.001). Achieving S8 resection required significantly longer clamping time (45 vs. 37 min, p = 0.011), more additional biliostasis because of obvious biliary leak (65 vs. 18 %, p < 0.001), and subsequently increased application of sealant material (56 vs. 9 %, p < 0.001) compared with RH. The overall complication rate was similar between the two groups (59 vs. 62 %, p = 0.804), although a trend toward a higher rate of biliary fistula was observed in S8 patients (20 vs. 6 %, p = 0.07). Routine CT scan performed on postoperative day 7 found significantly more subphrenic collections in S8 patients compared with RH patients (53 vs. 9 %, p = 0.003). On pathological examination, surgical margin width was comparable between the two groups. CONCLUSIONS: Anatomical S8 resection remains a technically demanding procedure with an elevated risk of postoperative biliary fistula but allows achieving adequate carcinologic resection. Increasing consideration for parenchymal sparing resection should lead to favor this approach as a treatment of choice for small and medium-sized tumors located in this segment.
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Fístula Biliar/etiología , Hepatectomía/efectos adversos , Hepatectomía/métodos , Neoplasias Hepáticas/cirugía , Adulto , Anciano , Fístula Biliar/epidemiología , Femenino , Humanos , Neoplasias Hepáticas/patología , Masculino , Persona de Mediana Edad , Estudios Retrospectivos , RiesgoRESUMEN
Bilio-bronchial fistula due to hydatid disease is a rare but severe condition. Three levels, abdominal, diaphragmatic and thoracic, may be involved, with high perioperative mortality. We report a case of bilio-bronchial fistula successfully managed by thoracotomy. Thoracotomy is the best approach for surgical treatment at all three levels.
Asunto(s)
Fístula Biliar/etiología , Enfermedades de las Vías Biliares/etiología , Fístula Bronquial/etiología , Equinococosis Hepática/complicaciones , Adulto , Fístula Biliar/epidemiología , Enfermedades de las Vías Biliares/epidemiología , Fístula Bronquial/epidemiología , Equinococosis Hepática/diagnóstico , Equinococosis Hepática/epidemiología , Equinococosis Pulmonar/complicaciones , Equinococosis Pulmonar/diagnóstico , Equinococosis Pulmonar/epidemiología , Humanos , MasculinoRESUMEN
OBJECTIVE: To report the case and surgical therapy of a patient with bilioptysis after vaginal delivery, caused by bronchobiliary fistula. Histologic analysis revealed endometrial glands embedded in the decidual stroma neighboring the liver and the lung. DESIGN: Case report. SETTING: University hospital. PATIENT(S): A 39-year-old patient, 7 days after vaginal delivery, without endometrial history. INTERVENTION(S): Synchronous liver and lung resection of a bronchobiliary fistula by laparotomy and a transdiaphragmatic approach. MAIN OUTCOME MEASURE(S): For complicated brochobiliary fistula caused by endometriosis, radical surgical treatment is mandatory. RESULT(S): Histopathologic analyses confirmed the presence of clusters of endometrial glands embedded in the decidual stroma that were neighboring the liver, and perifistulous lung tissue was shown to contain biliary pigment absorbed by macrophages and their derivatives. CONCLUSION(S): Hepatic and perihepatic endometriosis can cause a bronchobiliary fistula. Exacerbation of the symptoms can be triggered by high estrogen levels, physiologically dominating the last trimester. For such a rare case, surgery is mandatory.
Asunto(s)
Fístula Biliar/etiología , Enfermedades de las Vías Biliares/etiología , Fístula Bronquial/etiología , Endometriosis/complicaciones , Hepatopatías/complicaciones , Adulto , Fístula Biliar/diagnóstico , Fístula Biliar/epidemiología , Fístula Biliar/cirugía , Enfermedades de las Vías Biliares/diagnóstico , Enfermedades de las Vías Biliares/epidemiología , Enfermedades de las Vías Biliares/cirugía , Fístula Bronquial/diagnóstico , Fístula Bronquial/epidemiología , Fístula Bronquial/cirugía , Endometriosis/diagnóstico , Endometriosis/epidemiología , Endometriosis/cirugía , Femenino , Humanos , Incidencia , Hepatopatías/diagnóstico , Hepatopatías/epidemiología , Hepatopatías/cirugía , Periodo PospartoRESUMEN
CONTEXT: Tropical calcific pancreatitis is unique to developing countries with of unknown origin. OBJECTIVE: We evaluated the pattern of pancreaticobiliary ductal union in patients with tropical calcific pancreatitis. PATIENTS: Twenty-one patients with tropical calcific pancreatitis were compared to 174 control subjects with no pancreaticobiliary disease and 35 patients with alcohol-induced chronic pancreatitis. MAIN OUTCOME MEASURE: Two experienced people, blinded to the results, evaluated the pattern of pancreaticobiliary ductal union. Pancreaticobiliary ductal unions were classified as: separate ducts (no union), a short common-channel (length less than 6 mm), a long common-channel (length ranging 6-15 mm) and anomalous pancreaticobiliary ductal union (length greater than 15 mm). Anomalous union was defined as P-B type when the pancreatic duct appeared to join the bile duct and B-P type when the bile duct appeared to join the pancreatic duct. Any disparities between the two investigators were sorted out by mutual discussion. RESULTS: Pancreaticobiliary ductal union in tropical calcific pancreatitis patients as compared to those in the control group was as follows: separate ducts, 23.8% vs. 49.4% (P=0.036); a short common-channel, 4.8% vs. 28.7% (P=0.017); a long common channel, 33.3% vs. 18.4% (P=0.144) and anomalous pancreaticobiliary ductal union, 38.1% vs. 3.4% (P<0.001). The B-P pattern of anomalous pancreaticobiliary ductal union was more frequent in tropical calcific pancreatitis than in the control group but there was no statistical significance (P=0.103). The angle of the pancreaticobiliary ductal union in the tropical calcific pancreatitis group was 88.1 + or - 36.2 degrees as compared to 20.0 + or - 11.5 degrees in control group (P<0.001). Alcohol-induced chronic pancreatitis (No. 35) predominantly had either separate ducts (65.7%) or a short common channel (25.7%). CONCLUSION: We concluded that patients with tropical calcific pancreatitis in Kashmir had anomalous pancreaticobiliary ductal union, predominantly of B-P type with a wide angle of ductal union more frequently. This may be related to the etiology of tropical calcific pancreatitis in such regions.
Asunto(s)
Fístula Biliar/epidemiología , Fístula Pancreática/epidemiología , Pancreatitis/epidemiología , Adolescente , Adulto , Conductos Biliares/anomalías , Fístula Biliar/complicaciones , Fístula Biliar/diagnóstico por imagen , Calcinosis/complicaciones , Calcinosis/diagnóstico por imagen , Calcinosis/epidemiología , Estudios de Casos y Controles , Colangiopancreatografia Retrógrada Endoscópica , Femenino , Humanos , India/epidemiología , Masculino , Persona de Mediana Edad , Fístula Pancreática/complicaciones , Fístula Pancreática/diagnóstico por imagen , Pancreatitis/complicaciones , Pancreatitis/diagnóstico por imagen , Adulto JovenAsunto(s)
Enfermedades de los Conductos Biliares/etiología , Enfermedades de los Conductos Biliares/cirugía , Procedimientos Quirúrgicos del Sistema Biliar/métodos , Endoscopía del Sistema Digestivo/métodos , Adulto , Anciano , Anciano de 80 o más Años , Enfermedades de los Conductos Biliares/epidemiología , Enfermedades de los Conductos Biliares/patología , Fístula Biliar/epidemiología , Fístula Biliar/etiología , Fístula Biliar/patología , Fístula Biliar/cirugía , Constricción Patológica/epidemiología , Constricción Patológica/etiología , Constricción Patológica/patología , Constricción Patológica/cirugía , Humanos , Persona de Mediana Edad , Complicaciones Posoperatorias/epidemiología , Complicaciones Posoperatorias/etiología , Estudios Retrospectivos , Resultado del Tratamiento , Adulto JovenRESUMEN
BACKGROUND: Cholecystocolonic fistula (CCF) is the second most common cholecystoenteric fistula and is often discovered intraoperatively, resulting in a challenging situation for the surgeon, who is forced to switch to a complex procedure, often in old, unfit patients. Management of this uncommon but possible finding is still ill defined. METHODS: An extensive review of 160 articles published from 1950 to 2006 concerning 231 cases of CCF was performed. RESULTS: CCF is mostly an affliction of women in their sixth to seventh decades and is rarely diagnosed preoperatively. Chronic diarrhea is the key symptom in nonemergency patients, but, in one-fourth of cases, CCF presents with an acute onset, mostly biliary ileus. In one-fourth of patients, a second hepatobiliary abnormality is present, including gallbladder cancer in 2% of cases. In uncomplicated cases, diverting colostomy is not performed anymore, and laparoscopy treatment has been described in specialized centers. Symptomatic treatment of concomitant biliary ileus (without treating CCF) is a feasible option. Resolution of colonic biliary ileus by interventional endoscopy is reported. CONCLUSION: CCF should be considered in differential diagnosis of diarrhea, especially in old, female patients. A possible second hepatobiliary abnormality should be always investigated. Extemporaneous frozen section should be performed if gallbladder cancer is suspected. Depending on clinical presentation, different treatments for CCF are indicated, ranging from minimally invasive procedures to extensive resection.
Asunto(s)
Fístula Biliar/complicaciones , Enfermedades del Colon/complicaciones , Fístula Intestinal/complicaciones , Fístula Biliar/diagnóstico , Fístula Biliar/epidemiología , Fístula Biliar/cirugía , Enfermedades del Colon/diagnóstico , Enfermedades del Colon/epidemiología , Enfermedades del Colon/cirugía , Humanos , Fístula Intestinal/diagnóstico , Fístula Intestinal/epidemiología , Fístula Intestinal/cirugíaRESUMEN
The methods of diagnosis and operative treatment of internal (in 19 patients) and external (in 18) biliary fistulas, which appeared due to destructive and complicated forms of cholecystitis were analyzed.