RESUMEN
Abstract Acute pancreatitis is a rare condition in pregnancy, associated with a high mortality rate. Hypertriglyceridemia represents its second most common cause.We present the case of a 38-year-old woman in the 24th week of gestation with a history of hypertriglyceridemia and recurrent episodes of pancreatitis. She was admitted to our hospital with acute pancreatitis due to severe hypertriglyceridemia. She was stabilized and treated with fibrates. Despite her favorable clinical course, she developed a second episode of acute pancreatitis complicated by multi-organ dysfunction and pancreatic necrosis, requiring a necrosectomy. The pregnancy was ended by cesarean section, after which three plasmapheresis sessions were performed. She is currently asymptomatic with stable triglyceride levels. Acute pancreatitis due to hypertriglyceridemia represents a diagnostic and therapeutic challenge in pregnant women, associated with serious maternal and fetal complications. When primary hypertriglyceridemia is suspected, such as familial chylomicronemia syndrome, the most important objective is preventing the onset of pancreatitis.
Asunto(s)
Humanos , Femenino , Embarazo , Adulto , Complicaciones del Embarazo/diagnóstico , Diagnóstico Prenatal , Pancreatitis Aguda Necrotizante/diagnóstico , Hiperlipoproteinemia Tipo I/diagnóstico , Complicaciones del Embarazo/diagnóstico por imagen , APACHE , Pancreatitis Aguda Necrotizante/complicaciones , Pancreatitis Aguda Necrotizante/diagnóstico por imagen , Diagnóstico Diferencial , Hiperlipoproteinemia Tipo I/complicaciones , Hiperlipoproteinemia Tipo I/diagnóstico por imagenRESUMEN
Acute pancreatitis is a rare condition in pregnancy, associated with a high mortality rate. Hypertriglyceridemia represents its second most common cause. We present the case of a 38-year-old woman in the 24th week of gestation with a history of hypertriglyceridemia and recurrent episodes of pancreatitis. She was admitted to our hospital with acute pancreatitis due to severe hypertriglyceridemia. She was stabilized and treated with fibrates. Despite her favorable clinical course, she developed a second episode of acute pancreatitis complicated by multi-organ dysfunction and pancreatic necrosis, requiring a necrosectomy. The pregnancy was ended by cesarean section, after which three plasmapheresis sessions were performed. She is currently asymptomatic with stable triglyceride levels. Acute pancreatitis due to hypertriglyceridemia represents a diagnostic and therapeutic challenge in pregnant women, associated with serious maternal and fetal complications. When primary hypertriglyceridemia is suspected, such as familial chylomicronemia syndrome, the most important objective is preventing the onset of pancreatitis.
Asunto(s)
Hiperlipoproteinemia Tipo I/diagnóstico , Pancreatitis Aguda Necrotizante/diagnóstico , Complicaciones del Embarazo/diagnóstico , Diagnóstico Prenatal , APACHE , Adulto , Diagnóstico Diferencial , Femenino , Humanos , Hiperlipoproteinemia Tipo I/complicaciones , Hiperlipoproteinemia Tipo I/diagnóstico por imagen , Pancreatitis Aguda Necrotizante/complicaciones , Pancreatitis Aguda Necrotizante/diagnóstico por imagen , Embarazo , Complicaciones del Embarazo/diagnóstico por imagenAsunto(s)
Fluorodesoxiglucosa F18/farmacocinética , Corazón/diagnóstico por imagen , Hiperlipoproteinemia Tipo I/diagnóstico por imagen , Hiperlipoproteinemia Tipo I/metabolismo , Miocardio/metabolismo , Femenino , Humanos , Masculino , Persona de Mediana Edad , Cintigrafía , Radiofármacos/farmacocinética , Distribución Tisular , Adulto JovenRESUMEN
We present the imaging findings in an 8-week-old infant with LPL deficiency. Due to markedly increased lipoproteins in the serum, abnormal hypodensity and abnormal T1-weighted hyperintensity were identified in the dural venous sinuses and medullary veins.