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J Vet Med Sci ; 82(6): 779-783, 2020 Jun 24.
Artículo en Inglés | MEDLINE | ID: mdl-32378518

RESUMEN

A 3-years-old male golden retriever was presented for decreased activity (lethargy), anorexia, and titubation. Superficial lymph nodes were enlarged, and arrhythmia and tachycardia were auscultated. Fungal hyphae-like structures were detected in the biopsy samples from an enlarged lymph node and spleen. Nucleotide sequence of the internal transcribed spacer region of the fungi amplified by PCR was highly homologous to that of Inonotus pachyphloeus. The dog was treated with antifungal agents such as itraconazole, fluconazole, and voriconazole. Clinical signs resolved for 325 days but the dog died suddenly, possibly because of arrhythmia. Postmortem examination revealed the presence of a disseminated fungal infection. This report describes the case of canine systemic Inonotus sp. infection treated by an antifungal agent.


Asunto(s)
Enfermedades de los Perros/diagnóstico , Inonotus/aislamiento & purificación , Micosis/veterinaria , Animales , Antifúngicos/uso terapéutico , Arritmias Cardíacas/veterinaria , ADN de Hongos , ADN Espaciador Ribosómico , Enfermedades de los Perros/tratamiento farmacológico , Enfermedades de los Perros/microbiología , Perros , Inonotus/efectos de los fármacos , Inonotus/genética , Masculino , Micosis/diagnóstico , Micosis/tratamiento farmacológico , Micosis/microbiología , Reacción en Cadena de la Polimerasa , Taquicardia/veterinaria
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