Asunto(s)
Panadizo Interdigital , Hipernatremia/veterinaria , Lythraceae/envenenamiento , Neoplasias/veterinaria , Infecciones por Pasteurella/veterinaria , Inhibidores de la Angiogénesis/uso terapéutico , Animales , Factores de Coagulación Sanguínea , Bovinos , Enfermedades de los Bovinos/etiología , Panadizo Interdigital/prevención & control , Panadizo Interdigital/terapia , Enfermedades de los Caballos , Caballos , Neoplasias/tratamiento farmacológico , Infecciones por Pasteurella/prevención & control , Pasteurella multocida/genética , Aves de Corral , Enfermedades de las Aves de Corral/prevención & control , Ovinos , Enfermedades de las Ovejas/prevención & control , Porcinos , Enfermedades de los Porcinos/prevención & controlRESUMEN
CASE REPORT: Ingestion of pomegranates was associated with the deaths of 9 of 35 young cattle; 8 were found dead without any prior clinical signs being noted and 1 animal was observed to be weak with pale-pink mucous membranes. Gross pathological changes included widespread subcutaneous and serosal haemorrhages and the liver showed an enhanced acinar or 'nutmeg-like' pattern. The significant histopathological lesion was severe, acute periacinar to midzonal hepatocellular necrosis. These findings were considered characteristic of a hepatotoxicosis; however, other than the possible involvement of pomegranates, no known hepatotoxins were detected in the pasture or water sources. CONCLUSION: Consumption of large quantities of whole pomegranates is capable of causing severe hepatic necrosis resulting in the death of cattle. At this stage it is unknown whether the toxic principle is within the pomegranates or produced by a microbe associated with the deteriorating fruit.
