The Use of Bio-Inks and the Era of Bioengineering and Tooth Regeneration

Abstract Objective: To review existing literature and provide an update on the current use of Bio-Inks and potential future use. Material and Methods: A MeSH keyword search was conducted to find out relevant articles for this short review. Results: Bio inks used in 3D printing grafting require various properties essential for the selection. Combining multiple methods and improved properties is essential for developing successful bio-inks for 3D grafting of functional tissues and tooth pulp regeneration from stem cells. To date, researchers have made many efforts to grow teeth based on stem cells and inculcate regeneration of teeth along with surrounding tissues like alveolar bones and periodontal ligaments. Conclusion: 3D printing with Bio-Inks requires strict adherence to safety protocols for successful outcomes, making it difficult to employ this routinely.

Aspectos éticos del uso de identificadores biométricos / Bioethical aspects of the use of biometric identifiers / Aspectos éticos do uso de identificadores biométricos

La biometría ha tenido una rápida expansión como tecnología, siendo cada vez más accesible para el público general, prestando utilidad a los gobiernos y a la sociedad en el manejo de la seguridad ciudadana. Se aplica para la verificación o la identificación de la identidad de un individuo y, desde un punto de vista puramente técnico, constituye un problema de reconocimiento de patrones. En Chile, el marco legal acerca del manejo de datos personales no incluye específicamente a la biometría. A la fecha, se encuentra en trámite un nuevo proyecto de ley que considera tanto los datos biométricos como los perfiles biológicos. En otros países, los informes de las últimas dos décadas, que analizan el uso de biometría, plantean como principal foco de preocupación, desde el punto de vista ético, el derecho a la privacidad de los individuos, entregándose orientaciones prácticas acerca de la aplicación apropiada de estas tecnologías. Finalmente, desde un breve análisis de la biopolítica, se contextualiza el papel que cumple la biometría y los requerimientos éticos básicos para su desarrollo en dicho marco.

Biometrics has had a rapid expansion as a technology, being increasingly accessible to the public, and lending utility to governments and society in the management of citizen security. It is applied either for verification or for identification of an individual's identity and technically constitutes a problem of pattern recognition. In Chile, the existing legal framework regarding the handling of personal data does not include specific biometrics in its regulation. A new bill that considers both biometric data and Biological profiles is in process. In addition, we revised the international reports of the last two decades that analyze the use of biometrics. The primary focus of concern of these documents, from the ethical point of view, is the right to privacy of individuals, giving practical guidance and discussion regarding the elements necessary for the application of these novel technologies in an appropriate ethically manner. Finally, we contextualize from a brief analysis of biopolitics the role of biometrics and the basic ethical requirements for its development in that framework.

A biometria teve uma rápida expansão como tecnologia, sendo cada vez mais acessível para o público geral, sendo de utilidade para os governos e à sociedade no manejo da segurança cidadã. Ela pode ser aplicada para a verificação ou estabelecimento da identidade de um indivíduo e, desde um ponto de vista puramente técnico, constitui um problema de reconhecimento de padrões. No Chile, o contexto legal acerca do manejo de dados pessoais não inclui especificamente a biometria. Atualmente, encontra-se tramitando um novo projeto de lei que considera tanto os dados biométricos como os perfis biológicos. Em outros países, os informes das últimas duas décadas que analisam o uso da biometria, propõem como principal foco de preocupação, do ponto de vista ético, o direito à privacidade dos indivíduos, entregando-se orientações práticas acerca da aplicação apropriada destas tecnologias. Finalmente, desde uma breve análise da bio-política, contextualiza-se o papel que cumpre a biometria e os requerimentos éticos básicos para seu desenvolvimento em tal contexto legal.

In the immediate wake of Hoffman's independent review: Psychologist and general public perceptions.

In 2015, the American Psychological Association (APA) commissioned an independent review (IR) to examine APA's potential involvement with "enhanced interrogation" procedures following the 9/11 terrorist attacks. The IR concluded that certain APA officials acted together with the Department of Defense to "align APA and curry favor with" the Department of Defense to allow the involvement of psychologists in such enhanced interrogations (Hoffman et al., 2015, p. 9). Discussion following the IR's release underscored differences in the views of psychologists regarding the IR's conclusions. Despite extensive discussion, there is only anecdotal evidence regarding the views of psychologists on many of the questions investigated in the IR. This study examined the opinions of psychologists and the public shortly after the IR's release regarding the roles of psychologists in national security interrogations and other non-treatment-focused contexts. This survey of psychologists (N = 1,146) engaged in treatment-focused and non-treatment-focused activities, and of the general public (N = 522), sheds light on the broader perceptions of the IR's conclusions, and is relevant in considering future directions for the profession. Results suggest that the public is more accepting of psychologists' involvement in national security settings, including involvement in many of the activities highlighted as problematic in the IR, than are psychologists. The perceptions of treatment-focused and non-treatment-focused psychologists regarding the appropriate roles of psychologists in national security settings did not differ significantly. These empirical data should help inform the ongoing discussion in this area. None of the authors is associated with an unequivocal position on the IR or the issues addressed as part of it. (PsycInfo Database Record (c) 2020 APA, all rights reserved).

User abnormal behavior recommendation via multilayer network.

With the growing popularity of online services such as online banking and online shopping, one of the essential research topics is how to build a privacy-preserving user abnormal behavior recommendation system. However, a machine-learning based system may present a dilemma. On one aspect, such system requires large volume of features to pre-train the model, but on another aspect, it is challenging to design usable features without looking to plaintext private data. In this paper, we propose an unorthodox approach involving graph analysis to resolve this dilemma and build a novel private-preserving recommendation system under a multilayer network framework. In experiments, we use a large, state-of-the-art dataset (containing more than 40,000 nodes and 43 million encrypted features) to evaluate the recommendation ability of our system on abnormal user behavior, yielding an overall precision rate of around 0.9, a recall rate of 1.0, and an F1-score of around 0.94. Also, we have also reported a linear time complexity for our system. Last, we deploy our system on the "Wenjuanxing" crowd-sourced system and "Amazon Mechanical Turk" for other users to evaluate in all aspects. The result shows that almost all feedbacks have achieved up to 85% satisfaction.

Awareness and Attitudes of Research Students Toward Dual-use Research of Concern in Pakistan: A Cross-sectional Questionnaire.

Dual-use research poses a significant challenge for scientists in the biomedical field and for global health security in general. As the scientific knowledge and materials required for the development of biological agents become progressively more accessible and inexpensive, there is an increased need to understand and improve the governance of scientific research. Prevention of the misuse of facilities, equipment, agents, and scientific knowledge requires high levels of awareness of the concept of dual-use research, starting with early-career scientists and graduate students. In this study, the attitudes and level of awareness of postgraduate students in Pakistan toward the issues surrounding dual-use research were assessed through a survey containing both quantitative and qualitative questions in 32 universities in 4 provinces, federal area, and Azad Jammu and Kashmir regions of Pakistan; 933 students responded. Most (58.2%) had never heard of dual-use research of concern (DURC), while 18.5% had heard the term but were unsure of its meaning. Irrespective of prior knowledge, a higher percentage of students (68.6%) felt an obligation to report research misuse. Considering the need for DURC training, 94.1% of the respondents agreed that the principal investigator should take the responsibility to train students on DURC at the start of a research project. When experimental results having dual-use potential, 69.1% indicated they would publish with limited protocol, with 43.5% indicating they would publish the limited protocol only if there was a way for scientists to access their data. The survey results revealed limited DURC awareness among researchers across Pakistan. However, the respondents, although not formally educated about DURC, were quite aware of its impact. The information gained in this survey will be valuable in addressing country-specific awareness and training needs.

Revenge versus rapport: Interrogation, terrorism, and torture.

This review begins with the historical context of harsh interrogation methods that have been used repeatedly since the Second World War. This is despite the legal, ethical and moral sanctions against them and the lack of evidence for their efficacy. Revenge-motivated interrogations (Carlsmith & Sood, 2009) regularly occur in high conflict, high uncertainty situations and where there is dehumanization of the enemy. These methods are diametrically opposed to the humanization process required for adopting rapport-based methods-for which there is an increasing corpus of studies evidencing their efficacy. We review this emerging field of study and show how rapport-based methods rely on building alliances and involve a specific set of interpersonal skills on the part of the interrogator. We conclude with 2 key propositions: (a) for psychologists to firmly maintain the Hippocratic Oath of "first do no harm," irrespective of perceived threat and uncertainty, and (b) for wider recognition of the empirical evidence that rapport-based approaches work and revenge tactics do not. Proposition (a) is directly in line with fundamental ethical principles of practice for anyone in a caring profession. Proposition (b) is based on the requirement for psychology to protect and promote human welfare and to base conclusions on objective evidence. (PsycINFO Database Record

Use of pellet guns for crowd control in Kashmir: How lethal is "non-lethal"?

The use of pellet guns during the recent unrest in Kashmir as a method of crowd control has been questioned because of several deaths and numerous injuries. Across the world, these rubber pellets have been shown to inflict serious injuries, permanent disability, and death. The volatility of mob violence, inaccuracies in aim of the pellets, over-use of the pellet guns, and the perception of their harmlessness enhances the destructive potential of these so-called non-lethal weapons. There is also the larger ethical question whether any form of pain, however minimal, could be inflicted to control violent crowds.

Should a medical ethics journal discuss the actions of the security forces?

This refers to the comment "Use of pellet guns for crowd control in Kashmir: How lethal is 'non-lethal'?" by Siddarth David in the Indian Journal of Medical Ethics. My objection is not to the ethics of the use of pellet guns, but to the ethics of publishing such an article in a journal devoted to medical ethics.

A question of ethics, not nationalism: author's response.

The aim of the comment "Use of pellet guns for crowd control in Kashmir: How lethal is 'non-lethal'?" was neither to disparage the armed forces, nor recommend counterinsurgency strategies, nor support any particular community or group. It sought to raise discussions around the question pointed out by the responder himself, namely, "the ethical point of view" on the use of pellet guns in controlling violent mobs. The author also feels that the question is not so much about "favouring" the protestors or the security forces, but whether an instrument that causes significant fatalities and morbidities among bystanders should continue to be used as a method of crowd control.

Medical intelligence, security and global health: the foundations of a new health agenda.

Medical intelligence, security and global health are distinct fields that often overlap, especially as the drive towards a global health security agenda gathers pace. Here, we outline some of the ways in which this has happened in the recent past during the recent Ebola epidemic in West Africa and in the killing of Osama Bin laden by US intelligence services. We evaluate medical intelligence and the role it can play in global health security; we also attempt to define a framework that illustrates how medical intelligence can be incorporated into foreign policy action in order delineate the boundaries and scope of this growing field.

The Struggle Between Liberties and Authorities in the Information Age.

The "struggle between liberties and authorities", as described by Mill, refers to the tension between individual rights and the rules restricting them that are imposed by public authorities exerting their power over civil society. In this paper I argue that contemporary information societies are experiencing a new form of such a struggle, which now involves liberties and authorities in the cyber-sphere and, more specifically, refers to the tension between cyber-security measures and individual liberties. Ethicists, political philosophers and political scientists have long debated how to strike an ethically sound balance between security measures and individual rights. I argue that such a balance can only be reached once individual rights are clearly defined, and that such a definition cannot prescind from an analysis of individual well-being in the information age. Hence, I propose an analysis of individual well-being which rests on the capability approach, and I then identify a set of rights that individuals should claim for themselves. Finally, I consider a criterion for balancing the proposed set of individual rights with cyber-security measures in the information age.

Locked mental health wards: the answer to absconding?

A recent decision by the Queensland government to lock its 16 mental health inpatient facilities has met with condemnation by a number of professional bodies. This column canvasses some of the legal and ethical issues relating to locked wards and provides an overview of the literature on whether or not locking wards reduces absconding. It is argued that any benefits in preventing absconding through locking all mental health inpatient facilities is outweighed by the adverse effects locked wards have on those detained.