Asunto(s)
Cardiomiopatía Restrictiva , Neoplasias Cardíacas , Hemangiosarcoma , Humanos , Hemangiosarcoma/patología , Hemangiosarcoma/complicaciones , Hemangiosarcoma/diagnóstico , Neoplasias Cardíacas/patología , Neoplasias Cardíacas/complicaciones , Neoplasias Cardíacas/diagnóstico por imagen , Cardiomiopatía Restrictiva/patología , Cardiomiopatía Restrictiva/etiología , Masculino , Persona de Mediana Edad , Femenino , Resultado FatalRESUMEN
Malignant melanoma (MM) is notorious for its high metastatic potential, with cardiac metastasis being particularly severe as it involves cardiac structures and can lead to significant cardiac functional issues. While there is no standardized treatment approach, early detection and intervention can improve prognosis.
Asunto(s)
Ecocardiografía , Neoplasias Cardíacas , Neoplasias Intestinales , Melanoma , Humanos , Melanoma/secundario , Neoplasias Cardíacas/secundario , Neoplasias Cardíacas/diagnóstico por imagen , Ecocardiografía/métodos , Neoplasias Intestinales/secundario , Neoplasias Intestinales/diagnóstico por imagen , Masculino , Intestino Delgado , Persona de Mediana EdadRESUMEN
Cardiac tumors are rare and encompass a variety of presentations. Clinica symptoms are usually nonspecific, but they can present as obstructive, embolic, or constitutional symptoms. Treatment options and prognosis vary highly depending on the subtype, tumor size, and location. Surgical resection is usually the first-line therapy, except for cardiac lymphomas, and provides favorable long-term prognosis in most benign tumors. Cardiac sarcomas, however, are usually diagnosed in advanced stages, and the treatment relies on a multimodal approach with chemotherapy and radiotherapy. Metastatic cardiac tumors are usually related to advanced disease and carry an overall poor prognosis.
Asunto(s)
Neoplasias Cardíacas , Sarcoma , Humanos , Neoplasias Cardíacas/terapia , Neoplasias Cardíacas/patología , Neoplasias Cardíacas/diagnóstico por imagen , Sarcoma/terapia , Sarcoma/patología , PronósticoRESUMEN
The objective of this study was to evaluate semi-quantitatively the diagnostic performance of PET/CT metabolic parameters in differentiating benign or malignant cardiac or pericardial masses. A total of forty-one patients with newly diagnosed cardiac/pericardial masses who underwent 18F-FDG PET/CT were recruited. PET/CT metabolic parameters including the maximum standardized uptake value (SUVmax), mean standardized uptake value (SUVmean), total lesion glycolysis (TLG), tumor metabolic volume (MTV), the maximum tumor-to-mediastinal background ratio (TMR) and the maximum tumor-to-liver background ratio (TLR) is measured or calculated to evaluate the benign or malignant nature of cardiac/pericardial masses. Compared with benign cardiac/pericardial lesions, cardiac/pericardial malignancies had higher SUVmax, SUVmean, TLG, MTV, TMR, and TLR. All these PET/CT metabolic parameters showed high diagnostic performance in semi-quantitative evaluation of benign or malignant cardiac or pericardial masses, and SUVmean and MTV had the highest diagnostic accuracy. Therefore, PET/CT metabolic parameters can semi-quantitatively evaluate the benign or malignant cardiac/pericardial masses.
Asunto(s)
Fluorodesoxiglucosa F18 , Neoplasias Cardíacas , Pericardio , Tomografía Computarizada por Tomografía de Emisión de Positrones , Humanos , Tomografía Computarizada por Tomografía de Emisión de Positrones/métodos , Masculino , Femenino , Persona de Mediana Edad , Estudios Retrospectivos , Neoplasias Cardíacas/diagnóstico por imagen , Neoplasias Cardíacas/metabolismo , Anciano , Pericardio/diagnóstico por imagen , Pericardio/metabolismo , Pericardio/patología , Adulto , Radiofármacos , Anciano de 80 o más AñosRESUMEN
ST-segment elevation on the electrocardiogram typically indicates acute myocardial infarction but can mimic ST-segment elevation myocardial infarction in various conditions. We present a case of a patient with an intramyocardial mass and anterior ST-segment elevation without significant myocardial biomarker elevation. Multimodality imaging was crucial in revealing cardiac metastasis as the attributable cause.
Asunto(s)
Electrocardiografía , Neoplasias Cardíacas , Infarto del Miocardio con Elevación del ST , Humanos , Infarto del Miocardio con Elevación del ST/diagnóstico , Diagnóstico Diferencial , Neoplasias Cardíacas/secundario , Neoplasias Cardíacas/diagnóstico por imagen , Neoplasias Cardíacas/diagnóstico , Masculino , Persona de Mediana EdadAsunto(s)
Fibroelastoma Papilar Cardíaco , Humanos , Fibroelastoma Papilar Cardíaco/cirugía , Fibroelastoma Papilar Cardíaco/patología , Fibroelastoma Papilar Cardíaco/diagnóstico por imagen , Fibroelastoma Papilar Cardíaco/diagnóstico , Femenino , Neoplasias Cardíacas/diagnóstico por imagen , Neoplasias Cardíacas/cirugía , Neoplasias Cardíacas/patología , Masculino , Fibroma/cirugía , Fibroma/patología , AdultoRESUMEN
Cardiac myxoma is extremely rare in children. However, if not treated immediately, it may cause varying symptoms until sudden death. A-9-years old male Javanese child was brought to the emergency department of Prof. Soekandar General Hospital, Mojokerto with progressive dyspnoea since one month which got worse in the left decubitus position. There was no significant past medical history. Physical examination revealed hypotension, mitral stenosis, tricuspid regurgitation, and pulmonary congestion. Transthoracic echocardiography revealed a round pedunculated 3x3.3 cm mass in the Left Atrium that swingingly moved to the Left Ventricle during diastole. This was diagnosed provisionally as Myxoma with a differential of thrombus. After stabilization, he was referred to a tertiary hospital for emergency excision. Histopathology confirmed the myxoma. There were no symptoms and activity limitations during the 6 months follow-up. To the best of our knowledge, this is the first paediatric cardiac myxoma with Acute Heart Failure symptoms reported in Indonesia. Echocardiography is imperative for diagnosing myxoma. Appropriate and timely management results in an excellent outcome.
Asunto(s)
Ecocardiografía , Insuficiencia Cardíaca , Neoplasias Cardíacas , Mixoma , Humanos , Mixoma/complicaciones , Mixoma/cirugía , Mixoma/diagnóstico , Neoplasias Cardíacas/complicaciones , Neoplasias Cardíacas/cirugía , Neoplasias Cardíacas/diagnóstico , Neoplasias Cardíacas/diagnóstico por imagen , Masculino , Insuficiencia Cardíaca/etiología , Niño , Disnea/etiología , Atrios Cardíacos/diagnóstico por imagen , Atrios Cardíacos/patología , Enfermedad AgudaRESUMEN
We present the case of a 60-year-old male patient who was admitted to our hospital after experiencing a syncopal episode. First ECGs showed sinus rhythm with polymorphic premature ventricular complexes and later ventricular tachycardia with a left bundle branch block morphology were recorded. Imaging with TEE and MRI revealed a space-occupying lesion in the left ventricle, which was ultimately identified as a rare cardiac metastasis of renal cell carcinoma. Treatment was initiated with monoclonal antibodies resulting in lesion regression. This case highlights the importance of comprehensive diagnostic in patients with history of malignancy.
Asunto(s)
Carcinoma de Células Renales , Electrocardiografía , Neoplasias Cardíacas , Ventrículos Cardíacos , Neoplasias Renales , Taquicardia Ventricular , Humanos , Masculino , Persona de Mediana Edad , Neoplasias Cardíacas/secundario , Neoplasias Cardíacas/complicaciones , Neoplasias Cardíacas/diagnóstico por imagen , Taquicardia Ventricular/etiología , Taquicardia Ventricular/fisiopatología , Taquicardia Ventricular/diagnóstico , Neoplasias Renales/patología , Neoplasias Renales/diagnóstico por imagen , Ventrículos Cardíacos/diagnóstico por imagen , Carcinoma de Células Renales/secundario , Carcinoma de Células Renales/complicaciones , Carcinoma de Células Renales/diagnóstico por imagen , Imagen por Resonancia Magnética , Diagnóstico Diferencial , Ecocardiografía TransesofágicaRESUMEN
Transcatheter extraction of an intracardiac mass is a newer approach that may lead to nonsurgical treatment of complex cardiac masses. We present a case in which thrombectomy devices were combined to extract a right atrial mass, which highlights new frontiers in the treatment of complex transcatheter mass extraction. The combined use of two transcatheter thrombectomy devices (Kong and Godzilla) may provide a powerful addition to the existing armamentarium.
Asunto(s)
Cateterismo Cardíaco , Neoplasias Cardíacas , Trombectomía , Humanos , Trombectomía/instrumentación , Resultado del Tratamiento , Neoplasias Cardíacas/cirugía , Neoplasias Cardíacas/diagnóstico por imagen , Cateterismo Cardíaco/instrumentación , Diseño de Equipo , Masculino , Femenino , Atrios Cardíacos/cirugía , Atrios Cardíacos/diagnóstico por imagen , Catéteres Cardíacos , Ecocardiografía TransesofágicaRESUMEN
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Asunto(s)
Neoplasias Cardíacas , Mixoma , Recurrencia Local de Neoplasia , Humanos , Neoplasias Cardíacas/diagnóstico por imagen , Neoplasias Cardíacas/cirugía , Mixoma/diagnóstico por imagen , Mixoma/cirugía , Recurrencia Local de Neoplasia/diagnóstico por imagen , Femenino , Masculino , Persona de Mediana Edad , Ecocardiografía/métodosRESUMEN
Primary cardiac angiosarcomas are extremely rare, highly aggressive tumours with rapid progression and high metastatic capability. More than 60% of tumours are detected after the onset of a metastatic disease. In the two cases presented, we demonstrate the role of muti-modality imaging in the diagnosis of the lesion and provide valuable input in prognosticating the disease burden. In both cases, the diagnosis was suspected initially by imaging, based on radiological observations, before the final histopathology confirmation was made. Positron emission tomography- (PET-CT) was a critical component of the diagnostic workup for the detection of disease extent and volume of total disease burden. Hence, PET-CT imaging should be performed in all aggressive appearing cardiac tumours. In view of misleading clinical presentation, we suggest that aggressive workup to be performed in suspected patients. Young patients presenting with vague symptoms and those with recurrent, unresolving, unexplained pericardial effusion deserves special consideration.
Asunto(s)
Neoplasias Cardíacas , Hemangiosarcoma , Imagen Multimodal , Tomografía Computarizada por Tomografía de Emisión de Positrones , Humanos , Neoplasias Cardíacas/diagnóstico por imagen , Hemangiosarcoma/diagnóstico por imagen , Hemangiosarcoma/patología , Tomografía Computarizada por Tomografía de Emisión de Positrones/métodos , Masculino , Femenino , Adulto , Fluorodesoxiglucosa F18 , Persona de Mediana Edad , EcocardiografíaRESUMEN
Intracardiac lymphomas are exceedingly rare accounting for only 1% of all primary cardiac tumours. Historically, due to their insidious development and non-specific clinical presentation, the diagnosis has been challenging with most cases being confirmed on post-mortem examination. Our case report details the experience of a previously fit and active woman in her 60s who presented with gradual onset exertional dyspnoea. Through a series of multimodal imaging tools (including echocardiogram, cardiac MRI, CT and positron emission tomography-CT) and biopsy, we confirmed the diagnosis of intracardiac diffuse large B-cell lymphoma. Our patient was managed with chemotherapy and went on to demonstrate excellent radiological response with near-complete resolution of the intracardiac mass. Subjectively, our patient reported significant improvement in exercise tolerance within weeks of commencing treatment.
Asunto(s)
Neoplasias Cardíacas , Linfoma de Células B Grandes Difuso , Humanos , Linfoma de Células B Grandes Difuso/diagnóstico , Linfoma de Células B Grandes Difuso/tratamiento farmacológico , Linfoma de Células B Grandes Difuso/diagnóstico por imagen , Linfoma de Células B Grandes Difuso/patología , Femenino , Neoplasias Cardíacas/diagnóstico por imagen , Neoplasias Cardíacas/tratamiento farmacológico , Persona de Mediana Edad , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapéutico , Ecocardiografía , Disnea/etiología , Imagen por Resonancia Magnética , Tomografía Computarizada por Rayos X , Ciclofosfamida/uso terapéutico , Tomografía Computarizada por Tomografía de Emisión de Positrones , Diagnóstico Diferencial , Doxorrubicina/uso terapéutico , BiopsiaRESUMEN
BACKGROUND: Cardiac myxomas are the most common type of primary cardiac tumors in adults, but they can have variable features that make them difficult to diagnose. We report two cases of atrial myxoma with calcification or ossification, which are rare pathological subgroups of myxoma. CASE PRESENTATION: A 47-year-old woman and a 35-year-old man presented to our hospital with different symptoms. Both patients had a history of chronic diseases. Transthoracic and transesophageal echocardiography revealed a mass in the left or right atrium, respectively, with strong echogenicity and echogenic shadows. The masses were suspected to be malignant tumors with calcification or ossification. Contrast transthoracic echocardiography(cTEE) showed low blood supply within the lesions. The patients underwent surgical resection of the atrial mass, and the pathology confirmed myxoma with partial ossification or massive calcification. CONCLUSION: We report two rare cases of atrial myxoma with calcification or ossification and analyze their ultrasonographic features. Transthoracic echocardiography and cTEE can provide valuable information for the diagnosis and management of such mass. However, distinguishing calcification and ossification in myxoma from calcification in malignant tumors is challenging. More studies are needed to understand the pathogenesis and imaging characteristics of these myxoma variants.
Asunto(s)
Calcinosis , Atrios Cardíacos , Neoplasias Cardíacas , Mixoma , Osificación Heterotópica , Humanos , Mixoma/diagnóstico , Mixoma/cirugía , Mixoma/complicaciones , Neoplasias Cardíacas/diagnóstico , Neoplasias Cardíacas/cirugía , Neoplasias Cardíacas/complicaciones , Neoplasias Cardíacas/patología , Neoplasias Cardíacas/diagnóstico por imagen , Masculino , Persona de Mediana Edad , Calcinosis/diagnóstico por imagen , Calcinosis/diagnóstico , Calcinosis/cirugía , Atrios Cardíacos/patología , Atrios Cardíacos/diagnóstico por imagen , Femenino , Adulto , Osificación Heterotópica/diagnóstico , Osificación Heterotópica/complicaciones , Osificación Heterotópica/cirugía , Ecocardiografía , Ecocardiografía TransesofágicaRESUMEN
BACKGROUND Papillary fibroelastoma is the most common type of benign primary cardiac tumor and is usually asymptomatic. However, tumor fragments or surface thrombus can embolize and cause transient ischemic attacks, strokes, or myocardial infarction. This report describes a 76-year-old woman who presented with dysarthria and right-sided weakness due to a stroke associated with a left atrial papillary fibroelastoma. CASE REPORT A 76-year-old woman visited the Emergency Department because she had right-sided weakness and dysarthria from 12 h ago. Brain magnetic resonance image was done at the Emergency Department, showing multiple small embolic, acute infarction in left basal ganglia and fronto-temporo-parietal lobes. Transthoracic and transesophageal echocardiogram showed a hypermobile echogenic mass (0.8×1.5 cm) with villous surface on the orifice of left atrial appendage. Twenty-four-hour Holter monitoring was performed to evaluate the cause of cerebral infarction, and there was no paroxysmal atrial fibrillation. Thoracic computed tomography angiography also showed a sea anemone-shaped mass around the left atrial appendage. Cardiac tumor excision was done via a lower partial sternotomy. Histopathologic analysis showed multiple delicate fronds, and the avascular fibroelastic cores were lined by a single layer of CD31-positive endothelial cells. Histopathologic findings were consistent with papillary fibroelastoma. The patient was discharged without any other complications on day 30 of hospitalization. CONCLUSIONS This case highlights the importance of cardiac imaging in patients with acute stroke, including transthoracic and transesophageal echocardiography, which can show the typical imaging features of papillary fibroelastoma and other intracardiac sources of embolus.
Asunto(s)
Fibroelastoma Papilar Cardíaco , Accidente Cerebrovascular , Humanos , Femenino , Anciano , Accidente Cerebrovascular/etiología , Neoplasias Cardíacas/complicaciones , Neoplasias Cardíacas/diagnóstico por imagen , Neoplasias Cardíacas/cirugía , Atrios Cardíacos , Ecocardiografía TransesofágicaRESUMEN
BACKGROUND: Carney syndrome is an uncommon autosomal disorder closely linked to mutations in the PRKAR1A gene. Skin lesions are the most pronounced feature of Carney syndrome, affecting over 80% of individuals with this condition. This syndrome is characterized by a triad of myxomas, skin pigmentation, and endocrine hyperfunction, featuring multiple endocrine neoplasms with skin and cardiac involvement. Dilated cardiomyopathy, a primary cardiomyopathy, is defined as the dilation and impaired systolic function of the left or both ventricles. Its clinical presentation varies from being asymptomatic to heart failure or sudden cardiac death, making it a leading global cause of heart failure. Currently, Dilated cardiomyopathy has an estimated prevalence of 1/2500-1/250 individuals, predominantly affecting those aged 30-40 years, with a male-to-female ratio of 3:1. This case report describes a heart failure patient with cardiac myxoma caused by Carney syndrome combined with dilated cardiomyopathy. The patient was successfully treated for heart failure by heart transplantation. CASE PRESENTATION: Herein, we report a case of heart failure due to Carney syndrome that resulted in cardiac myxoma combined with dilated cardiomyopathy. A 35-year-old male was admitted to the hospital three years ago because of sudden chest tightness and shortness of breath. Echocardiography indicated myxoma, and a combination of genetic screening and physical examination confirmed Carney syndrome with cardiac myxoma. Following symptomatic management, he was discharged. Surgical interventions were not considered at the time. However, the patient's chest tightness and shortness of breath symptoms worsened, and he returned to the hospital. A New York Heart Association grade IV heart function was confirmed, and echocardiography indicated the presence of dilated cardiomyopathy accompanied by cardiac myxoma. Ultimately, the patient's heart failure was successfully treated with heart transplantation. CONCLUSIONS: Cardiac myxoma caused by Carney syndrome combined with heart failure caused by dilated cardiomyopathy can be resolved by heart transplantation.