RESUMEN
The growing frequency of authorized generics has important implications for the welfare of prescription drug consumers. Authorized generic entry could affect the timing of generic entry, brand-name and generic prices, and generic penetration. We reviewed 1999-2003 data and found that generic entry in the absence of short-run exclusivity restrictions benefits consumers through lower short-run prices. We suggest that these benefits likely also result from authorized generics. We posit that long-run prices and shares are likely essentially unaffected by authorized generics and that potential costs to consumers from any delayed generic entry are likely small.
Asunto(s)
Comportamiento del Consumidor/estadística & datos numéricos , Medicamentos Genéricos/economía , Honorarios Farmacéuticos/estadística & datos numéricos , Ciprofloxacina/economía , Aprobación de Drogas/métodos , Aprobación de Drogas/estadística & datos numéricos , Combinación de Medicamentos , Etinilestradiol/economía , Humanos , Comercialización de los Servicios de Salud/métodos , Comercialización de los Servicios de Salud/estadística & datos numéricos , Norgestrel/análogos & derivados , Norgestrel/economía , Paroxetina/economía , Estados UnidosRESUMEN
BACKGROUND: Emergency contraception (EC) can potentially reduce unwanted pregnancies and abortions. However, these agents are underused due to lack of awareness and barriers to utilization. While earlier economic evaluations have indicated that use of EC is potentially cost-effective, recent evidence of a lower risk of pregnancy following unprotected intercourse than previously reported suggest prior studies may have over-estimated cost savings. OBJECTIVES: To model cost savings and pregnancy-related outcomes associated with the policy change authorizing pharmacist provision of EC in British Columbia, and to estimate the costs of initiatives to further women's awareness and utilization of EC that would result. METHODS: Three decision analytic models were developed evaluating current EC utilization (physician-only), EC utilization following pharmacist provision and potential expanded EC awareness and utilization following a public awareness initiative. Models were developed from the Ministry of Health perspective for 2001 using cost and event data from the Ministry supplemented by data from the literature. RESULTS: Current EC utilization saved the Ministry $2.20 million (95% CR: $0.15 million, $4.90 million) in medical costs the first year, and incremental savings from pharmacist provision was $0.64 million (95% CR: $0.24 million, $1.28 million). A public awareness initiative costing less than $2.57 million (95% CR: $0.22 million, $5.75 million) annually is potentially cost saving. CONCLUSIONS: Pharmacist provision of EC was cost saving to the Ministry, even when the estimated risk of pregnancy in the population is less than assumed in previous studies. Increasing EC availability directly from pharmacists and increasing EC awareness have the potential to reduce health care costs.
Asunto(s)
Anticonceptivos Poscoito/economía , Anticonceptivos Poscoito/provisión & distribución , Técnicas de Apoyo para la Decisión , Utilización de Medicamentos/economía , Evaluación de Resultado en la Atención de Salud , Servicios Farmacéuticos/economía , Pautas de la Práctica en Medicina/economía , Colombia Británica , Ahorro de Costo/estadística & datos numéricos , Árboles de Decisión , Utilización de Medicamentos/estadística & datos numéricos , Etinilestradiol/economía , Etinilestradiol/provisión & distribución , Femenino , Educación en Salud/economía , Conocimientos, Actitudes y Práctica en Salud , Accesibilidad a los Servicios de Salud/economía , Humanos , Levonorgestrel/economía , Levonorgestrel/provisión & distribución , Norgestrel/economía , Norgestrel/provisión & distribución , Servicios Farmacéuticos/estadística & datos numéricos , Pautas de la Práctica en Medicina/estadística & datos numéricos , Embarazo , Embarazo no DeseadoRESUMEN
BACKGROUND: Emergency contraception, which prevents pregnancy after unprotected sexual intercourse, has the potential to reduce significantly the incidence of unintended pregnancy and the consequent need for abortion and to reduce medical care costs. AIM: To determine the savings generated by use of Postinor-2, the levonorgestrel regimen of emergency hormonal contraception, in Australia. METHODS: We modelled the cost savings when women obtain Postinor-2 directly from a pharmacist where cost savings are measured as the cost of pregnancies averted by use of Postinor-2 per dollar spent on Postinor-2. RESULTS: Each dollar spent on a single treatment with Postinor-2 saves A$2.27-A$3.81 in direct medical care expenditures on unintended pregnancy depending on assumptions about savings from costs avoided by preventing mistimed births. Postinor-2 is cost-saving even under the least favourable assumption that mistimed births when prevented today occur 2 years later. Results are robust even to large changes in model input parameters. CONCLUSION: Emergency contraception is cost saving. More extensive use of emergency contraception could save considerable medical and social costs by reducing unintended pregnancies, which are expensive.