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1.
PLoS One ; 19(10): e0311559, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-39392826

RESUMEN

OBJECTIVE: To establish experimental models of radical hysterectomy based on Querleu-Morrow classification, and clarify the quantitative evaluation of pelvic neural injuries and acute voiding changes postoperatively. METHODS: Female Sprague Dawley rats were randomized and received sham operation, type A, B1, C1 and C2 radical hysterectomies (as the injury gradually increased), respectively. The excised specimens were collected for hematoxylin and eosin staining and Pgp9.5 (pan-neuronal marker) immunohistochemistry to evaluate the facial and neural resection of paracervix. At 21 days after operation, 5 rats in each group were used for urine spot test, awake cystometry and leak point pressure test, and the other 5 ones were used for hematoxylin and eosin staining of bladder and pelvic neural plane, and Masson's trichrome staining of bladder. RESULTS: Paracervical Pgp9.5 immunohistochemistry revealed that the resected neural area in C2 group was significantly larger than that in type A, B1, and C1 groups. Compared with type A and B1 groups, the excised paracervical facial area was significant higher in type C1 and C2 groups. The occurrence of urinary retention was 0%, 10%, 40% and 100% in type A, B1, C1 and C2 groups, respectively, which was further confirmed by average residual volume. The incidence of neurogenic bladder and its severity gradually increased from type A to type C2 groups, consistent with the findings of leakage point pressure, bladder size, bladder weight, pathological changes and collagen deposition. Neuropathological evaluation revealed neural injuries involved the main components of pelvic neural plane. CONCLUSION: The novel rat models of radical hysterectomy based on Querleu-Morrow classification revealed the structural and functional changes of voiding after operation, which reflected the situation in humans.


Asunto(s)
Histerectomía , Ratas Sprague-Dawley , Vejiga Urinaria , Animales , Femenino , Histerectomía/efectos adversos , Ratas , Vejiga Urinaria/patología , Vejiga Urinaria/fisiopatología , Micción/fisiología , Pelvis/patología , Pelvis/inervación , Modelos Animales de Enfermedad , Vejiga Urinaria Neurogénica/etiología , Vejiga Urinaria Neurogénica/fisiopatología , Vejiga Urinaria Neurogénica/patología
2.
Nat Commun ; 15(1): 8972, 2024 Oct 17.
Artículo en Inglés | MEDLINE | ID: mdl-39419980

RESUMEN

Neurogenic bladder often occurs after pelvic ganglia injury. Its symptoms, like severe urinary retention and incontinence, have a significant impact on individuals' quality of life. Unfortunately, there are currently no effective treatments available for this type of injury. Here, we designed a fiber-enhanced tissue bandage for injured pelvic ganglia. Tight junctions formed in tissue bandages create a mini tissue structure that enhances resistance in an in vivo environment and delivers growth factors to support the healing of ganglia. Strength fibers are similar to clinical bandages and guarantee ease of handling. Furthermore, tissue bandages can be stored at low temperatures over 5 months without compromising cell viability, meeting the requirements for clinical products. A tissue bandage was applied to a male rat with a bilateral major pelvic ganglia crush injury. Compared to the severe neurogenic bladder symptoms observed in the injury and scaffold groups, tissue bandages significantly improved bladder function. We found that tissue bandage increases resistance to mechanical injury by boosting the expression of cytoskeletal proteins within the major pelvic ganglia. Overall, tissue bandages show promise as a practical therapeutic approach for ganglia repair, offering hope for developing more effective treatments for this thorny condition.


Asunto(s)
Vendajes , Vejiga Urinaria Neurogénica , Animales , Masculino , Ratas , Vejiga Urinaria Neurogénica/terapia , Vejiga Urinaria Neurogénica/etiología , Ratas Sprague-Dawley , Pelvis/inervación , Pelvis/lesiones , Ganglios/metabolismo , Vejiga Urinaria/inervación , Cicatrización de Heridas/fisiología
3.
J Trop Pediatr ; 70(6)2024 Oct 04.
Artículo en Inglés | MEDLINE | ID: mdl-39424291

RESUMEN

Musculoskeletal infection of pelvis can be confused with septic arthritis of the hip, irritable hip, sacroiliitis, and spondylodiscitis in the initial period. This study aimed to present the complete clinical picture of pelvic infective osteomyelitis (PIO) in children along with its natural course. Two researchers independently used PubMed and Scopus electronic databases for the literature review. This review includes all studies reporting PIO in the pediatric age group. The final inclusion of 11 eligible studies was done. A total of 277 patients were analyzed from the included studies with the majority of males (158/242, 65.2%). Hip and groin pain (147/195, 75.3%) and limp (155/249, 62.2%) were the common presenting symptoms. Increased systemic temperature (83/103, 80.5%) and localized tenderness at the hip joint area (90/121, 74.3%) were among the commonest signs. Magnetic resonance imaging was an investigation of choice for diagnosis (89/93, 95.6%). Blood culture showed growth in 47.6% (119/250) patients with Staphylococcus aureus (83/102, 81.3%) being the most common isolated organism. Treatment with sensitive antibiotics was the mainstay of management with surgery for debridement or biopsy being required in only 16.1% (23/142) of the patients. PIO in children is a rare condition mimicking several other disease processes affecting the neighboring tissues the diagnosis of which gets limited in low-resource settings. Further prospective clinical studies are the need of the hour to validate the guideline proposed. Explorative studies to define a clinical scoring system to differentiate septic arthritis of the hip from PIO may be considered.


Asunto(s)
Antibacterianos , Imagen por Resonancia Magnética , Osteomielitis , Humanos , Osteomielitis/diagnóstico , Osteomielitis/microbiología , Niño , Masculino , Femenino , Antibacterianos/uso terapéutico , Preescolar , Adolescente , Artritis Infecciosa/diagnóstico , Artritis Infecciosa/microbiología , Pelvis , Infecciones Estafilocócicas/diagnóstico , Infecciones Estafilocócicas/tratamiento farmacológico , Staphylococcus aureus/aislamiento & purificación , Desbridamiento
4.
Sensors (Basel) ; 24(19)2024 Oct 09.
Artículo en Inglés | MEDLINE | ID: mdl-39409523

RESUMEN

A key best practice to prevent and treat pressure injuries (PIs) is to ensure at-risk individuals are repositioned regularly. Our team designed a non-contact position detection system that predicts an individual's position in bed using data from load cells under the bed legs. The system was originally designed to predict the individual's position as left-side lying, right-side lying, or supine. Our previous work suggested that a higher precision for detecting position (classifying more than three positions) may be needed to determine whether key bony prominences on the pelvis at high risk of PIs have been off-loaded. The objective of this study was to determine the impact of categorizing participant position with higher precision using the system prediction F1 score. Data from 18 participants was collected from four load cells placed under the bed legs and a pelvis-mounted inertial measurement unit while the participants assumed 21 positions. The data was used to train classifiers to predict the participants' transverse pelvic angle using three different position bin sizes (45°, ~30°, and 15°). A leave-one-participant-out cross validation approach was used to evaluate classifier performance for each bin size. Results indicated that our prediction F1 score dropped as the position category precision was increased.


Asunto(s)
Lechos , Úlcera por Presión , Humanos , Úlcera por Presión/prevención & control , Úlcera por Presión/diagnóstico , Masculino , Adulto , Femenino , Posicionamiento del Paciente/métodos , Postura/fisiología , Presión , Adulto Joven , Fenómenos Biomecánicos/fisiología , Pelvis/lesiones
5.
Sci Data ; 11(1): 1162, 2024 Oct 22.
Artículo en Inglés | MEDLINE | ID: mdl-39438488

RESUMEN

Radiographic landmark annotation determines patients' anatomical parameters and influences diagnoses. However, challenges arise from ambiguous region-based definitions, human error, and image quality variations, potentially compromising patient care. Additionally, AI landmark localization often presents its predictions in a probability-based heatmap format, which lacks a corresponding clinical standard for accuracy validation. This Data Descriptor presents a clinical benchmark dataset for pelvic tilt landmarks, gathered through a probabilistic approach to measure annotation accuracy within clinical environments. A retrospective analysis of 115 pelvic sagittal radiographs was conducted for annotating pelvic tilt parameters by five annotators, revealing landmark cloud sizes of 6.04 mm-17.90 mm at a 95% dataset threshold, corresponding to 9.51°-16.55° maximum angular disagreement in clinical settings. The outcome provides a quantified point cloud dataset for each landmark corresponding to different probabilities, which enables assessment of directional annotation distribution and parameter-wise impact, providing clinical benchmarks. The data is readily reusable for AI studies analyzing the same landmarks, and the method can be easily replicated for establishing clinical accuracy benchmarks of other landmarks.


Asunto(s)
Benchmarking , Pelvis , Humanos , Pelvis/diagnóstico por imagen , Radiografía , Inteligencia Artificial , Estudios Retrospectivos , Puntos Anatómicos de Referencia
6.
PLoS One ; 19(10): e0312480, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-39441879

RESUMEN

PURPOSE: The objective of the study was to initially validate the hypothesis about the relationship between the pelvic tilt angle in the saggital plane and the functional state of muscles stabilising the lumbo-pelvic-hip (LPH) complex expressed as a change in their stiffness in a tensiomyography examination. MATERIALS AND METHODS: Forty five women aged 19-30 years took part in an observational (cross-sectional) study. The examination involved measurements using the tensiomyography method (TMG). The stiffness of muscles stabilising the LPH complex expressed as a maximal muscle displacement (Dm variable) was assessed and the relationship between muscle stiffness and the value of the pelvic tilt (PT) in the sagittal plane was determined. RESULTS: The analysis showed significant differences in the values of medians of the muscle displacement (Dm) values in groups identified in terms of the value of pelvic tilt (Table 1) for Erector Spinae (ES) muscles (p = 0.0012), Gluteus Maximus (GM) muscles (p = 0.0004), Rectus Abdominis (RA) muscles (p = 0.0005), Obliquus abdominis externus (OAE) muscles (p = 0.0002*) and Rectus Femoris (RF) muscles (p = 0.0071). The results of the correlation analysis performed using the Spearman rho correlation coefficient between the value of pelvic tilt and muscle stiffness (Dm) show the following significant relations for ES muscles (p = 0<0.0001), GM muscles (p<0.0001), RA muscles (p<0.0001) and OAE muscles (p<0.0001). However, a clear direction of changes in stiffness in accordance with the description of relations defined as Lower Crossed Syndrome was not confirmed. CONCLUSIONS: A tensiomyographic examination did not show clear relations between the value of pelvic tilt and stiffness of muscles stabilising the lumbar-pelvic-hip complex. The mechanism of Lower Crossed Syndrome (LCS) may be not the only model explaining the relations between musculofascial structures of the hip-lumbar area. The implications of the LCS should not be the only basis for the therapy of disorders resulting from an incorrect position of the pelvis in the sagittal plane.


Asunto(s)
Pelvis , Humanos , Femenino , Adulto , Adulto Joven , Estudios Transversales , Pelvis/fisiología , Músculo Esquelético/fisiología , Cadera/fisiología , Miografía/métodos , Región Lumbosacra/fisiología
7.
World J Surg Oncol ; 22(1): 262, 2024 Sep 30.
Artículo en Inglés | MEDLINE | ID: mdl-39350212

RESUMEN

OBJECTIVE: This study sought to explore the efficiency of para-aortic and pelvic lymphadenectomy in the treatment of locally advanced cervical cancer (LACC) with pelvic lymph node (PLN) metastasis. METHODS: A total of 171 LACC patients with imaging-confirmed pelvic lymph node metastasis were included in this study. These patients were divided into two groups: the surgical staging group, comprising 58 patients who had received para-aortic and pelvic lymphadenectomy (surgical staging) along with concurrent chemoradiation therapy (CCRT), and the imaging staging group, comprising 113 patients who had received only CCRT. The two groups' progression-free survival (PFS), overall survival (OS) and treatment-related complications were compared. RESULTS: The surgical staging group started radiotherapy 10.2 days (range 9-12 days) later than the imaging staging group. The overall incidence of lymphatic cysts was 9.30%. In the surgical staging group, para-aortic lymph node metastasis was identified in 34.48% (20/58) of patients, while pathology-negative PLN was observed in 12.07% (7/58). Over a median follow-up period of 52 months, no significant differences in PFS and OS rates were found between the two groups (p > 0.05). Subgroup analysis of patients with lymph node diameters of ≥ 1.5 cm revealed a five-year PFS rate of 75.0% and an OS rate of 80.0% in the surgical staging group, compared to 41.5% and 50.1% in the imaging staging group, respectively, showing statistically significant differences (p = 0.022, HR:0.34 [0.13, 0.90] and p = 0.038, HR: 0.34 [0.12,0.94], respectively for PFS and OS). Additionally, in patients with two or more metastatic lymph nodes, the five-year PFS and OS rates were 69.2% and 73.1% in the surgical staging group, versus 41.0% and 48.4% in the imaging staging group, with these differences also being statistically significant (p = 0.025, HR: 0.41[0.19,0.93] and p = 0.046, HR: 0.42[0.18,0.98], respectively). CONCLUSION: Performing surgical staging before CCRT is safe and delivers accurate lymph node details crucial for tailoring radiotherapy. This approach merits further investigation, particularly in women with pelvic lymph nodes measuring 1.5 cm or more in diameter or patients with two or more imaging-positive PLNs.


Asunto(s)
Escisión del Ganglio Linfático , Ganglios Linfáticos , Metástasis Linfática , Pelvis , Neoplasias del Cuello Uterino , Humanos , Femenino , Neoplasias del Cuello Uterino/patología , Neoplasias del Cuello Uterino/cirugía , Neoplasias del Cuello Uterino/terapia , Neoplasias del Cuello Uterino/mortalidad , Escisión del Ganglio Linfático/métodos , Persona de Mediana Edad , Adulto , Estudios de Seguimiento , Tasa de Supervivencia , Ganglios Linfáticos/patología , Ganglios Linfáticos/cirugía , Pelvis/patología , Pelvis/cirugía , Pronóstico , Anciano , Estudios Retrospectivos , Quimioradioterapia/métodos , Estadificación de Neoplasias , Aorta/patología , Aorta/cirugía , Carcinoma de Células Escamosas/patología , Carcinoma de Células Escamosas/cirugía , Carcinoma de Células Escamosas/terapia , Carcinoma de Células Escamosas/mortalidad , Carcinoma de Células Escamosas/secundario
8.
J Orthop Trauma ; 38(11S): S29-S34, 2024 Nov 01.
Artículo en Inglés | MEDLINE | ID: mdl-39431812

RESUMEN

OBJECTIVES: To quantify the occupational radiation exposure with a 3-dimensional (3D) fluoroscopic machine during routine use in pelvic and acetabular surgery and to determine whether the additional radiation exposure encountered with the 3D fluoroscopic spin is within previously accepted limits. DESIGN: Prospective cohort study. SETTING: Level I trauma center. PATIENT SELECTION CRITERIA: All patients undergoing 3D fluoroscopy intraoperatively during pelvis (OTA/AO 61B,C) or acetabular (OTA/AO 62A-C) surgery between April 2021 and July 2021. OUTCOME MEASURES AND COMPARISONS: Radiation dose at standardized locations around the operating room during the spin portion of the 3D fluoroscopy. RESULTS: Seventy-six 3D spins were performed on 69 patients during the study period. The average emitted radiation dose from the machine for the routine fluoroscopy portion of the case was 74.5 mGy. The average displayed radiation dose in the air for the spin portion of the case was 39.9 mGy, an average of 53.6% less radiation than the routine fluoroscopy portion. For the spin portion, the average radiation exposure seen by the patient was 3.42 mGy (centered on the patient) and the average maximal exposure in the room was 0.062 mGy. Minimal radiation was detected outside the operating room doors. CONCLUSIONS: The radiation exposure encountered by operating room personnel with 3D fluoroscopy appears to be within safe occupational limits. The marginal increase in radiation exposure during pelvic and acetabular surgery should not discourage the use of 3D imaging intraoperatively. LEVEL OF EVIDENCE: Level IV, Case Series.


Asunto(s)
Acetábulo , Imagenología Tridimensional , Exposición Profesional , Exposición a la Radiación , Humanos , Fluoroscopía , Exposición Profesional/prevención & control , Acetábulo/cirugía , Acetábulo/diagnóstico por imagen , Estudios Prospectivos , Exposición a la Radiación/prevención & control , Masculino , Femenino , Persona de Mediana Edad , Adulto , Huesos Pélvicos/diagnóstico por imagen , Huesos Pélvicos/lesiones , Huesos Pélvicos/cirugía , Dosis de Radiación , Quirófanos , Procedimientos Ortopédicos , Pelvis/diagnóstico por imagen , Pelvis/cirugía
9.
J Int Med Res ; 52(10): 3000605241281678, 2024 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-39360384

RESUMEN

OBJECTIVES: An abscess is a localized collection of pus contained within a fibrous capsule. In this study, we aimed to determine the demographic pattern, common anatomical sites, risk factors, and the microbial profile of abscesses in different body sites among children. METHODS: We conducted a prospective study in our pediatric surgical department among children with abscesses in different body sites between January 2019 and December 2022. RESULTS: During the study period, 85 children were included. The participant age range was 0 to 14 years old, and 66% of participants were boys. The most common anatomical sites where abscesses formed were the pelvis (n = 29, 34%), abdomen (n = 22, 26%), neck (n = 14, 16%), and extremities (n = 12, 14%). Risk factors of abscesses in different body sites included cannulation, lymphadenitis, mastitis, perforated appendix, and perianal fistula. We observed that 74% of abscesses were of a polymicrobial nature. CONCLUSION: The most common anatomical sites for abscesses in children included the pelvis, abdomen, neck, and extremities. Most abscesses in these sites were polymicrobial in nature.


Asunto(s)
Absceso , Humanos , Niño , Masculino , Femenino , Estudios Prospectivos , Preescolar , Adolescente , Lactante , Absceso/microbiología , Absceso/patología , Factores de Riesgo , Recién Nacido , Pelvis/patología , Cuello/microbiología , Cuello/patología , Extremidades/patología
10.
Radiat Oncol ; 19(1): 132, 2024 Oct 01.
Artículo en Inglés | MEDLINE | ID: mdl-39354612

RESUMEN

PURPOSE: This study aimed to use propensity score matching (PSM) to explore the long-term outcomes and failure patterns in locally advanced rectal cancer (LARC) patients with positive versus negative lateral pelvic lymph node (LPLN). MATERIALS AND METHODS: Patients with LARC were retrospectively divided into LPLN-positive and LPLN-negative groups. Clinical characteristics were compared between the groups using the chi-square test. PSM was applied to balance these differences. Progression-free survival (PFS) and overall survival (OS), and local-regional recurrence (LRR) and distant metastasis (DM) rates were compared between the groups using the Kaplan-Meier method and log-rank tests. RESULTS: A total of 651 LARC patients were included, 160 (24.6%) of whom had positive LPLN and 491 (75.4%) had negative LPLN. Before PSM, the LPLN-positive group had higher rates of lower location (53.1% vs. 43.0%, P = 0.025), T4 stage (37.5% vs. 23.2%, P = 0.002), mesorectal fascia (MRF)-positive (53.9% vs. 35.4%, P < 0.001) and extramural venous invasion (EMVI)-positive (51.2% vs. 27.2%, P < 0.001) disease than the LPLN-negative group. After PSM, there were 114 patients for each group along with the balanced clinical factors, and both groups had comparable surgery, pathologic complete response (pCR), and ypN stage rates. The median follow-up was 45.9 months, 3-year OS (88.3% vs. 92.1%, P = 0.276) and LRR (5.7% vs. 2.8%, P = 0.172) rates were comparable between LPLN-positive and LPLN-negative groups. Meanwhile, despite no statistical difference, 3-year PFS (78.8% vs. 85.9%, P = 0.065) and DM (20.4% vs. 13.3%, P = 0.061) rates slightly differed between the groups. 45 patients were diagnosed with DM, 11 (39.3%) LPLN-positive and 3 (17.6%) LPLN-negative patients were diagnosed with oligometastases (P = 0.109). CONCLUSIONS: Our study indicates that for LPLN-positive patients, there is a tendency of worse PFS and DM than LPLN-negative patients, and for this group patients, large samples are needed to further confirm our conclusion.


Asunto(s)
Quimioradioterapia , Ganglios Linfáticos , Metástasis Linfática , Puntaje de Propensión , Neoplasias del Recto , Humanos , Neoplasias del Recto/patología , Neoplasias del Recto/terapia , Neoplasias del Recto/mortalidad , Masculino , Femenino , Persona de Mediana Edad , Estudios Retrospectivos , Anciano , Ganglios Linfáticos/patología , Pelvis , Adulto , Recurrencia Local de Neoplasia/patología , Recurrencia Local de Neoplasia/terapia , Tasa de Supervivencia , Pronóstico
11.
Medicina (Kaunas) ; 60(10)2024 Oct 01.
Artículo en Inglés | MEDLINE | ID: mdl-39459396

RESUMEN

Background and Objectives: Stroke patients often experience changes in their pelvic tilt, trunk impairments and decreased gait and balance. While various therapeutic interventions have been attempted to improve these symptoms, there is a need for interventions that are easy to apply and reduce the physical labor of physical and occupational therapists. We aimed to investigate the immediate effects of two different methods of trunk elastic taping on the pelvic inclination, trunk impairment, balance, and gait in chronic stroke patients. Materials and Methods: We performed a single-blind randomized controlled trial involving 45 patients with chronic stroke. Participants were randomly assigned to one of three groups: forward rotation with posterior pelvic tilt taping (FRPPT, n = 14), backward rotation with posterior pelvic tilt taping (BRPPT, n = 14), or placebo taping (PT = 14). This study was conducted from December 2023 to January 2024. All the measurements were performed twice: before the intervention and immediately after the intervention. The pelvic inclination was assessed using the anterior pelvic tilt angle. The trunk impairment scale (TIS) was used to measure the trunk impairment. The balance and gait were evaluated using a force plate and walkway system. Results: The pelvic inclination was significantly different in the FRPPT and BRPPT groups compared to the PT group (p < 0.05, p < 0.001). The TIS and gait were significantly increased in the FRPPT group compared to the PT group (p < 0.05). The balance significantly improved in the FRPPT and BRPPT within groups (p < 0.05). Conclusions: Two different methods of posterior pelvic tilt taping improved the anterior pelvic tilt in chronic hemiplegic stroke patients compared with PT, and the FRPPT method also improved the trunk impairment and gait. Therefore, posterior pelvic tilt taping can be used as an intervention with immediate effect.


Asunto(s)
Marcha , Equilibrio Postural , Accidente Cerebrovascular , Humanos , Masculino , Femenino , Persona de Mediana Edad , Método Simple Ciego , Equilibrio Postural/fisiología , Accidente Cerebrovascular/fisiopatología , Accidente Cerebrovascular/complicaciones , Accidente Cerebrovascular/terapia , Marcha/fisiología , Anciano , Rehabilitación de Accidente Cerebrovascular/métodos , Rehabilitación de Accidente Cerebrovascular/instrumentación , Torso/fisiopatología , Pelvis/fisiopatología , Cinta Atlética , Adulto
13.
BMC Musculoskelet Disord ; 25(1): 845, 2024 Oct 24.
Artículo en Inglés | MEDLINE | ID: mdl-39448960

RESUMEN

PURPOSE: Total Hip Arthroplasty (THA) is the primary treatment for hip diseases today. Nevertheless, total hip arthroplasty has its challenges, and one of these challenges is the potential for incorrect execution of the preoperative planning process. Such errors can lead to complications such as loosening and instability of the prosthesis and leg length discrepancy. In this study, we used human phantoms to investigate the influence of pelvic and femoral factors on prosthesis size selection in the preoperative planning of total hip arthroplasty and to provide a reference standard for clinical imaging in preoperative planning of total hip arthroplasty. METHODS: In this experiment, we utilised a custom-made experimental device that enabled us to manipulate the movement of the pelvis and femur in various directions. The device also incorporated sensors to control the angle of movement. By obtaining X-rays from different positions and angles, we were able to determine the size of the prosthesis based on the 2D preoperative planning generated by the mediCAD software. RESULTS: When the pelvis was in a nonneutral position, the size of the acetabular cup varied within a range of three sizes. Similarly, when the femur was in a nonneutral position, the size of the femoral stem varied within a range of two sizes. The movement of the pelvis and femur in the coronal plane, relative to the neutral position, did not impact the selection of the prosthesis size. However, the motion of the pelvis and femur in the sagittal and transverse planes had a notable effect. CONCLUSION: The selection of the prosthesis size for preoperative planning can be significantly influenced by specific positions of the pelvis and femur. It is crucial for the radiographer to ensure that the pelvis and femur maintain a standard neutral position, particularly in the sagittal and transverse planes, during the image acquisition process.


Asunto(s)
Artroplastia de Reemplazo de Cadera , Fémur , Prótesis de Cadera , Diseño de Prótesis , Humanos , Artroplastia de Reemplazo de Cadera/instrumentación , Artroplastia de Reemplazo de Cadera/métodos , Fémur/cirugía , Fémur/diagnóstico por imagen , Pelvis/cirugía , Pelvis/diagnóstico por imagen , Cuidados Preoperatorios/métodos , Fantasmas de Imagen
14.
PLoS One ; 19(10): e0312082, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-39480782

RESUMEN

INTRODUCTION: Older women are at increased risk of spinal misalignment and its associated complications. This study investigated the influence of age, grip strength, and various sagittal spinal parameters on spinal alignment. The results indicate the need for comprehensive management strategies. METHODS: This cross-sectional study included 200 older women who underwent bone health evaluations at the orthopedic department of a hospital. The study participants underwent dual-energy X-ray absorptiometry, grip strength measurement, and full-length spine radiography. Clinical and radiographic parameters were analyzed through Pearson correlation and linear regression analyses. RESULTS: Significant correlations were identified between grip strength and spinal parameters such as C7 slope and global tilt, indicating that muscle strength affects spinal alignment. Advanced age was associated with changes in sagittal spinal parameters, indicating that changes occur in body compensation over time. Furthermore, pelvic parameters such as pelvic tilt and sacral slope were significantly correlated with spinal curvature, indicating their critical roles in maintaining spinal stability. CONCLUSIONS: This study revealed the critical roles of muscle strength and pelvic alignment in the management of spinal health in older women with low bone mass. Targeted interventions for increasing muscle strength, correcting posture, and achieving hormonal balance can notably improve spinal stability and reduce the risk of associated complications. Longitudinal studies should be conducted to validate and refine the intervention strategies and to extend the study findings.


Asunto(s)
Vértebras Cervicales , Humanos , Femenino , Estudios Transversales , Anciano , Taiwán , Vértebras Cervicales/diagnóstico por imagen , Vértebras Cervicales/fisiología , Fuerza de la Mano/fisiología , Fuerza Muscular/fisiología , Persona de Mediana Edad , Absorciometría de Fotón , Anciano de 80 o más Años , Pelvis/diagnóstico por imagen , Pelvis/fisiología
15.
Bone Joint J ; 106-B(11): 1206-1215, 2024 Nov 01.
Artículo en Inglés | MEDLINE | ID: mdl-39481438

RESUMEN

Understanding spinopelvic mechanics is important for the success of total hip arthroplasty (THA). Despite significant advancements in appreciating spinopelvic balance, numerous challenges remain. It is crucial to recognize the individual variability and postoperative changes in spinopelvic parameters and their consequential impact on prosthetic component positioning to mitigate the risk of dislocation and enhance postoperative outcomes. This review describes the integration of advanced diagnostic approaches, enhanced technology, implant considerations, and surgical planning, all tailored to the unique anatomy and biomechanics of each patient. It underscores the importance of accurately predicting postoperative spinopelvic mechanics, selecting suitable imaging techniques, establishing a consistent nomenclature for spinopelvic stiffness, and considering implant-specific strategies. Furthermore, it highlights the potential of artificial intelligence to personalize care.


Asunto(s)
Artroplastia de Reemplazo de Cadera , Humanos , Fenómenos Biomecánicos , Artroplastia de Reemplazo de Cadera/métodos , Columna Vertebral/diagnóstico por imagen , Prótesis de Cadera , Huesos Pélvicos/diagnóstico por imagen , Huesos Pélvicos/anatomía & histología , Pelvis/diagnóstico por imagen
16.
World J Urol ; 42(1): 605, 2024 Oct 30.
Artículo en Inglés | MEDLINE | ID: mdl-39476127

RESUMEN

OBJECTIVE: To evaluate the effectiveness of extended (e-PLND) and super-extended pelvic lymph node dissection (se-PLND) during robot-assisted radical prostatectomy (RARP) by examining lymph node (LN) yield, complications, LN metastasis, and biochemical recurrence (BCR) incidence. METHODS: Between January 2016 and January 2020, 354 consecutive patients with > 5% risk of lymph node involvement (LNI), as predicted by the Memorial Sloan Kettering Cancer Center nomogram, underwent RARP with (s)e-PLND at a high-volume center. The e-PLND involved removing fibrofatty lymphatic tissue around the obturator fossa, internal iliac region, and external iliac vessels. The se-PLND, performed at the discretion of the surgeons, also included lymph nodes from the pre-sacral and common iliac regions. Outcomes included histopathological findings by anatomical region; complications; and BCR incidence during follow-up. RESULTS: The median LNI risk was 18% (IQR 9-31%). A median of 22 LN (IQR 16-28) were removed, with se-PLND yielding a higher number: 25 (IQR 20-32) compared to e-PLND: 17 (IQR 13-24) (p < 0.001). pN1 disease was detected in 22% of patients overall, higher in se-PLND (29%) than e-PLND (14%) (p < 0.001). Of metastatic LNs, 14% were situated outside the e-PLND template. Operation time was longer for se-PLND, but perioperative complications were similar between both groups. After a median follow-up of 24 months (IQR 7-33), BCR incidence was comparable between the two groups. CONCLUSION: Compared to standard extended pelvic lymph node dissection (PLND), super extended PLND increases lymph node yield and removal of metastatic deposits but does not contribute to progression free survival at mid-term.


Asunto(s)
Escisión del Ganglio Linfático , Recurrencia Local de Neoplasia , Complicaciones Posoperatorias , Prostatectomía , Neoplasias de la Próstata , Humanos , Masculino , Prostatectomía/métodos , Escisión del Ganglio Linfático/métodos , Neoplasias de la Próstata/cirugía , Neoplasias de la Próstata/patología , Persona de Mediana Edad , Recurrencia Local de Neoplasia/epidemiología , Anciano , Complicaciones Posoperatorias/epidemiología , Estudios Retrospectivos , Metástasis Linfática , Procedimientos Quirúrgicos Robotizados , Antígeno Prostático Específico/sangre , Pelvis
17.
Acta Oncol ; 63: 822-832, 2024 Oct 29.
Artículo en Inglés | MEDLINE | ID: mdl-39473177

RESUMEN

BACKGROUND AND PURPOSE: To review available data on toxicity during and/or after treatment of abdominal-pelvic lymph node oligometastases (A-P LN) with stereotactic body radiation therapy (SBRT) and to provide an overview of adverse events and its relation to dose or fractionation. MATERIAL AND METHODS: For this systematic review, we searched MEDLINE, Embase, Web of Science Core Collection, and CINAH for studies published between the database inception and October 3rd, 2023. Inclusion criteria were (1) patients with 1-5 A-P LN oligometastases, (2) treatment with SBRT to a median prescribed dose of ≥55 Gy BED10, and (3) description of acute and/or late toxicity. There were no language or date restrictions. RESULTS: A total of 35 studies, including 1,512 patients, were selected. Late grade 3 and 4 adverse events occurred in 0.6% and 0.1% of the patients treated for A-P LN oligometastases. All late adverse events grade ≥ 3 occurred after treatment of the tumor with a minimum BED10 of 72 Gy. Of the 11 patients with severe late toxicity, five patients were re-irradiated. Late grade 2 and 1 toxicity was reported in 3.4% and 8.3% of the patients. Acute toxicity grades 4, 3, 2, and 1 occurred in 0.1%, 0.2%, 4.4%, and 19.8% of the patients, respectively. INTERPRETATION: SBRT for A-P LN oligometastases show low toxicity rates. Nearly 50% of late adverse events ≥ grade 3 were associated with re-irradiation.


Asunto(s)
Metástasis Linfática , Pelvis , Radiocirugia , Humanos , Radiocirugia/efectos adversos , Radiocirugia/métodos , Pelvis/efectos de la radiación , Ganglios Linfáticos/patología , Ganglios Linfáticos/efectos de la radiación , Abdomen , Fraccionamiento de la Dosis de Radiación , Neoplasias Abdominales/secundario , Neoplasias Abdominales/radioterapia , Neoplasias Pélvicas/secundario , Neoplasias Pélvicas/radioterapia
18.
J Orthop Surg Res ; 19(1): 700, 2024 Oct 29.
Artículo en Inglés | MEDLINE | ID: mdl-39468623

RESUMEN

BACKGROUND: Medial tibial stress syndrome (MTSS) is a prevalent running-related injury that could impact athletic performance and quality of life. The purpose of the study was to investigate the effectiveness of functional hip abductor strength training on reducing contralateral pelvic drop angle (hip frontal plane projection angle), and dynamic knee valgus (knee frontal plane projection angle) in runners with medial tibial stress syndrome (MTSS). METHODS: Forty male and female recreational runners were diagnosed with MTSS for at least one month. The age ranged from 25 to 35 years old, and the body mass index (BMI) ranged between (18.5 and 25 kg/m2) participated in this study. This was a single-blind, randomized controlled trial. Participants were randomized into two groups: a control group (Group A, n = 20) received a selected physical therapy exercise program, and an experimental group (Group B, n = 20) received the same program plus functional hip abductor strength training. Dynamic knee valgus (frontal plane projection angle) and contralateral pelvic drop angle were measured using 2D video and analyzed by Kinovea software at baseline and after 8 weeks. Mixed-effect multifactor analysis of variance (MANOVA) was conducted to compare within and between groups effects on FPPA and pelvic drop angle. RESULTS: After 8 weeks, Group B exhibited a significantly decreased frontal plane projection and pelvic drop angles compared to Group A (p < 0.05). Group A also demonstrated a reduced pelvic drop angle, but to a lesser extent, and their frontal plane projection angle increased. CONCLUSIONS: This study demonstrates that 8 weeks of functional hip abductor strength training, combined with traditional physical therapy, effectively improves lower extremity kinematics in runners with MTSS by reducing dynamic knee valgus and contralateral pelvic drop. This targeted approach likely addresses underlying muscle weakness and movement dysfunction, offering hope for potentially reducing MTSS recurrence. TRIAL REGISTRATION: clinicaltrials.gov. NO: NCT05637476. Date: December 1, 2022.


Asunto(s)
Síndrome de Estrés Medial de la Tibia , Carrera , Humanos , Masculino , Adulto , Carrera/fisiología , Femenino , Método Simple Ciego , Síndrome de Estrés Medial de la Tibia/terapia , Síndrome de Estrés Medial de la Tibia/etiología , Entrenamiento de Fuerza/métodos , Articulación de la Rodilla/fisiopatología , Terapia por Ejercicio/métodos , Pelvis/fisiopatología , Cadera , Resultado del Tratamiento
19.
Medicine (Baltimore) ; 103(43): e39684, 2024 Oct 25.
Artículo en Inglés | MEDLINE | ID: mdl-39470549

RESUMEN

This study aims to analyze the safety, feasibility, and short-term oncology outcomes of selective laparoscope lateral lymph node dissection (LLND) with total mesorectal excision surgery. Between December 2019 and May 2023, LLND with total mesorectal excision surgery was performed in 47 selected patients with advanced rectal cancer. Surgical complications and 2-year oncology survival outcomes were analyzed in the study. All 47 procedures were technically successful without converting conversion to open surgery. The mean operation time was 200.6 minutes (135-321 minutes), and the mean estimated blood loss was 92.9 mL (range 10-2000 mL). The most common postoperative complications were anastomotic (8.5%, n = 4), ileus (6.4%, n = 3), and chyle leakage (4.3%, n = 2). Lateral pelvic lymph node metastases were found in 19 (40.4%) patients. When divided into lateral pelvic lymph node positive and negative groups, there was no significant impact on overall survival (94.4% vs 100%, Log-rank P = .596) and local recurrence-free survival (LFRS) (76.7% vs 89.6%, Log-rank P = .210), except disease-free survival (DFS) (58.3% vs 90.2%, Log-rank P = .005). Subgroup analysis showed similar short-term survival outcomes between the pN+ group and the internal iliac metastasis group (Log-rank P of overall survival, LFRS, and DFS were all ˃.05). LRFS and DFS in the obturator or external iliac metastasis group were worse than those in the internal iliac metastasis group when the follow-up time was extended (Log-rank P of LFRS and DFS were .05 and .063). Selective laparoscopy LLND for rectal cancer is safety and feasibility, and its complications are manageable. Oncology survival outcomes for lateral pelvic lymph node metastases limited to the internal iliac are similar to the pN+ stage; therefore, it should be treated positively.


Asunto(s)
Laparoscopía , Escisión del Ganglio Linfático , Complicaciones Posoperatorias , Neoplasias del Recto , Humanos , Neoplasias del Recto/cirugía , Neoplasias del Recto/patología , Neoplasias del Recto/mortalidad , Escisión del Ganglio Linfático/métodos , Escisión del Ganglio Linfático/efectos adversos , Masculino , Femenino , Laparoscopía/métodos , Laparoscopía/efectos adversos , Persona de Mediana Edad , Estudios Retrospectivos , Anciano , Adulto , Complicaciones Posoperatorias/epidemiología , Metástasis Linfática , Tempo Operativo , Estudios de Factibilidad , Resultado del Tratamiento , Supervivencia sin Enfermedad , Pelvis
20.
J Robot Surg ; 18(1): 386, 2024 Oct 29.
Artículo en Inglés | MEDLINE | ID: mdl-39470929

RESUMEN

As the global surgical robotic ecosystem diversifies, multi-platform surgery is becoming increasingly common. The natural question is whether these robots differ in performance and cost. We address this question and report the first systematic review comparing platforms. A systematic search identified clinical studies comparing at least two platforms. Of 287 studies, 31 were included, with 5 RCTs and 26 cohort studies, including 3624 patients. All studies compared da Vinci with Hintori, Hugo, KangDuo, Micro-Hand, Revo-I, Senhance, and Versius robots. Comparisons were across specialties: urology (18 studies; upper and lower tract), general surgery (11 studies; inguinal and ventral hernia, cholecystectomy, colorectal, pancreatic, oesophagectomy, distal gastrectomy), gynaecology (3 studies; hysterectomy, sacrocolpopexy). There were no differences in conversion rate, estimated blood loss, complication rate, pathological parameters, oncological outcomes (6 months), and functional outcomes (12 months). Results were mixed on operative time and its components. Length of stay was largely similar. Surgeon task load was similar (2 studies). Operative cost was 45-60% lower on the newer platforms (3 studies). Operative, clinical, oncological, and functional outcomes were similar for da Vinci and the newer robots across a range of abdominopelvic procedures, with a signal of lower cost on newer types. Studies were heterogeneous. Data on non-technical skills, other human factors, and comparative learning curves was scant. The majority of evidence was low quality and retrospective. However, accumulating evidence on safety, efficacy, and non-inferiority of the newer platforms has implications for robotic training programmes and procurement.


Asunto(s)
Abdomen , Pelvis , Procedimientos Quirúrgicos Robotizados , Procedimientos Quirúrgicos Robotizados/métodos , Procedimientos Quirúrgicos Robotizados/economía , Procedimientos Quirúrgicos Robotizados/estadística & datos numéricos , Humanos , Abdomen/cirugía , Pelvis/cirugía , Resultado del Tratamiento , Femenino , Tempo Operativo , Tiempo de Internación/estadística & datos numéricos
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