RESUMEN
The effect of surface protein deposits on the oxygen permeability of polyhydroxyethylmethacrylate ( polyHEMA ) gel contact lenses was studied using: (1) previously worn lenses with protein deposits accumulated in vivo, and (2) new lenses with protein deposited in vitro. The oxygen permeability (Dk) of the protein-deposited in vivo lenses was determined before and after cleaning, and that of the new lenses before and after in vitro protein deposition. For both groups of lenses, the oxygen permeability did not change significantly after either cleaning (in vivo lenses) or protein deposition (in vitro lenses). It is concluded that surface protein deposits on polyHEMA lenses do not alter the oxygen permeability of the lenses.
Asunto(s)
Lentes de Contacto Hidrofílicos/normas , Polihidroxietil Metacrilato/normas , Ácidos Polimetacrílicos/normas , Humanos , Técnicas In Vitro , Oxígeno , Permeabilidad , ProteínasRESUMEN
The physiochemical properties of a hydrogel used as a scleral buckling implant for retinal detachment surgery are described. The new material was prepared by simultaneous polymerization and crosslinking of 2-hydroxyethyl acrylate with methyl acrylate and ethylene diacrylate, in the presence of an inert diluent, ethylene glycol. At equilibrium swelling, the hydrogen absorbed 17% water and had a durometer hardness (DH) of 15 (Shore Durometer A-2). A unique property of this material was its swelling hysteresis; when the gel swollen in 70% ethanol was placed in water, it retained a high level of hydration (75% water) and softness (DH 8), and most of its elasticity and strength as well. Then the swelling decreased very slowly so that the implant reached its ultimate size at equilibrium swelling in ca. 1 year. This property is especially useful in the scleral buckling procedure, in which a soft implant indents the sclera over the detached retina until reattachment is achieved. In addition to this advantage, this hydrogel is more elastic and stronger than available hydrogels of similar softness.
