Asunto(s)
Poroma , Neoplasias de las Glándulas Sudoríparas , Humanos , Poroma/diagnóstico por imagen , Poroma/cirugía , Imagenología Tridimensional , Diagnóstico Diferencial , Neoplasias de las Glándulas Sudoríparas/diagnóstico por imagen , Neoplasias de las Glándulas Sudoríparas/cirugía , Microscopía ConfocalRESUMEN
Poroma is skin cancer that arises from the sweat gland cells. Its diagnosis could be difficult. Line-field optical coherence tomography (LC-OCT) is a novel imaging technique that has shown promise in the diagnosis and monitoring of various skin conditions. We report a case of poroma diagnosed by LC-OCT.
Asunto(s)
Poroma , Neoplasias Cutáneas , Neoplasias de las Glándulas Sudoríparas , Humanos , Poroma/diagnóstico por imagen , Neoplasias de las Glándulas Sudoríparas/diagnóstico por imagen , Tomografía de Coherencia Óptica , Glándulas SudoríparasRESUMEN
PURPOSE: The purpose of this study was to evaluate magnetic resonance (MR) imaging findings of poroma and porocarcinoma. METHODS: Six patients (3 male, 3 female; age range, 40-84 years; mean age, 61 years) with histologically confirmed skin appendage tumors with apocrine and eccrine differentiation (2 poromas and 4 porocarcinomas) were enrolled. All patients underwent preoperative MR imaging and the MR images were retrospectively reviewed. RESULTS: The configurations were classified as pedunculated solid in 5 lesions and subcutaneous cystic with mural nodules in 1. Well-demarcated deep tumor margins and smooth skin surfaces were observed in all 6 lesions, and peritumoral fat stranding was observed in 2. In all 5 pedunculated solid lesions, T2-hyperintense foci, T1 hyperintensity, and homogeneous solid components were observed within the lesions. CONCLUSIONS: Poroma and porocarcinoma usually exhibited pedunculated solid homogeneous lesion. Intratumoral T2-hyperintense foci and T1 hyperintensity were observed in pedunculated solid lesions.
Asunto(s)
Porocarcinoma Ecrino/diagnóstico por imagen , Poroma/diagnóstico por imagen , Neoplasias de las Glándulas Sudoríparas/diagnóstico por imagen , Adulto , Anciano , Anciano de 80 o más Años , Diagnóstico Diferencial , Porocarcinoma Ecrino/patología , Femenino , Humanos , Imagen por Resonancia Magnética , Masculino , Persona de Mediana Edad , Poroma/patología , Estudios Retrospectivos , Neoplasias de las Glándulas Sudoríparas/patologíaRESUMEN
Eccrine porocarcinoma (EPC) is a rare malignant skin tumor. The dermoscopy of invasive EPC reveals focal presence of whitish-pink, structureless areas surrounded by pinkish-white halos. In an eccrine poroma (EP), such areas present diffuse distribution in the "frog- eggs" pattern. We reported an EPC in situ that presents a transitional dermoscopy pattern between EP and invasive EPC. We found a diffuse distribution; whitish-pink, structureless areas surrounded by pinkish-white halos; a central exulceration and a polymorphic vascular pattern.
Asunto(s)
Porocarcinoma Ecrino/diagnóstico por imagen , Poroma/diagnóstico por imagen , Neoplasias de las Glándulas Sudoríparas/diagnóstico por imagen , Anciano , Biopsia , Dermoscopía/métodos , Diagnóstico Diferencial , Porocarcinoma Ecrino/patología , Femenino , Humanos , Pierna , Poroma/patología , Neoplasias de las Glándulas Sudoríparas/patologíaRESUMEN
Abstract Eccrine porocarcinoma (EPC) is a rare malignant skin tumor. The dermoscopy of invasive EPC reveals focal presence of whitish-pink, structureless areas surrounded by pinkish-white halos. In an eccrine poroma (EP), such areas present diffuse distribution in the "frog- eggs" pattern. We reported an EPC in situ that presents a transitional dermoscopy pattern between EP and invasive EPC. We found a diffuse distribution; whitish-pink, structureless areas surrounded by pinkish-white halos; a central exulceration and a polymorphic vascular pattern.
Asunto(s)
Humanos , Femenino , Anciano , Neoplasias de las Glándulas Sudoríparas/diagnóstico por imagen , Poroma/diagnóstico por imagen , Porocarcinoma Ecrino/diagnóstico por imagen , Neoplasias de las Glándulas Sudoríparas/patología , Biopsia , Dermoscopía/métodos , Diagnóstico Diferencial , Poroma/patología , Porocarcinoma Ecrino/patología , PiernaRESUMEN
Abstract: Poroid neoplasms are benign epithelial proliferations with eccrine sweat gland differentiation. They are a challenging diagnosis because of the clinical heterogeneity, being able to mimic several malignant neoplasms. They are classified into classic poroma, hidroacanthoma simplex, dermal duct tumor and poroid hidradenoma. Association of histological subtypes occurs in more than 25% of cases. We report a case of a combined poroid neoplasia of classical poroma and poroid hidradenoma, reviewing its dermatoscopic features.
Asunto(s)
Humanos , Femenino , Anciano , Neoplasias de las Glándulas Sudoríparas/patología , Neoplasias de las Glándulas Sudoríparas/diagnóstico por imagen , Poroma/patología , Poroma/diagnóstico por imagen , DermoscopíaRESUMEN
Poroid neoplasms are benign epithelial proliferations with eccrine sweat gland differentiation. They are a challenging diagnosis because of the clinical heterogeneity, being able to mimic several malignant neoplasms. They are classified into classic poroma, hidroacanthoma simplex, dermal duct tumor and poroid hidradenoma. Association of histological subtypes occurs in more than 25% of cases. We report a case of a combined poroid neoplasia of classical poroma and poroid hidradenoma, reviewing its dermatoscopic features.
Asunto(s)
Poroma/diagnóstico por imagen , Poroma/patología , Neoplasias de las Glándulas Sudoríparas/diagnóstico por imagen , Neoplasias de las Glándulas Sudoríparas/patología , Anciano , Dermoscopía , Femenino , HumanosRESUMEN
Cutaneous adnexal tumors include lesions with apocrine, eccrine, follicular, sebaceous, and mixed differentiation. Most are benign and sporadic, although malignant forms are occasionally observed and some cases develop in the setting of inherited syndromes. These tumors often cause immense diagnostic difficulty. Dermoscopy is a noninvasive technique that has greatly improved the diagnostic accuracy of different skin lesions, including these tumors. We provide a review of the literature on the dermoscopic structures and patterns associated with adnexal tumors. Most patterns associated with this kind of tumor are nonspecific and are observed in other nonadnexal tumors, especially in basal cell carcinomas.
Asunto(s)
Adenoma/diagnóstico por imagen , Carcinoma/diagnóstico por imagen , Dermoscopía , Enfermedades del Cabello/diagnóstico por imagen , Nevo Sebáceo de Jadassohn/diagnóstico por imagen , Neoplasias de las Glándulas Sebáceas/diagnóstico por imagen , Glándulas Sebáceas/patología , Neoplasias de las Glándulas Sudoríparas/diagnóstico por imagen , Acrospiroma/diagnóstico por imagen , Síndrome de Birt-Hogg-Dubé/diagnóstico por imagen , Carcinoma Adenoide Quístico/diagnóstico por imagen , Quiste Folicular/diagnóstico por imagen , Hidrocistoma/diagnóstico por imagen , Humanos , Hiperplasia/diagnóstico por imagen , Neoplasias Basocelulares/diagnóstico por imagen , Síndromes Neoplásicos Hereditarios/diagnóstico por imagen , Pilomatrixoma/diagnóstico por imagen , Poroma/diagnóstico por imagen , Neoplasias Cutáneas/diagnóstico por imagen , Siringoma/diagnóstico por imagen , Adenomas Tubulares de las Glándulas Sudoríparas/diagnóstico por imagenAsunto(s)
Enfermedad de Bowen/diagnóstico por imagen , Granuloma Piogénico/diagnóstico por imagen , Melanoma/diagnóstico por imagen , Poroma/diagnóstico por imagen , Neoplasias Cutáneas/diagnóstico por imagen , Anciano , Enfermedad de Bowen/cirugía , Dermoscopía , Diagnóstico Diferencial , Estudios de Seguimiento , Humanos , Masculino , Neoplasias Cutáneas/cirugía , Resultado del TratamientoRESUMEN
BACKGROUND: Poromas are benign cutaneous sweat gland tumours that are challenging to identify. The dermoscopic features of poromas are not well characterized. OBJECTIVE: To determine the clinical-dermoscopic features of poromas. METHODS: Cross-sectional, observational study of 113 poromas and 106 matched control lesions from 16 contributors and eight countries. Blinded reviewers evaluated the clinical and dermoscopic features present in each clinical and dermoscopic image. RESULTS: Poromas were most commonly non-pigmented (85.8%), papules (35.4%) and located on non-acral sites (65.5%). In multivariate analysis, dermoscopic features associated with poroma included white interlacing areas around vessels (OR: 7.9, 95% CI: 1.9-32.5, P = 0.004), yellow structureless areas (OR: 2.5, 95% CI: 1.1-6.0, P = 0.04), milky-red globules (OR: 3.9, 95% CI: 1.4-11.1, P = 0.01) and poorly visualized vessels (OR: 33.3, 95% CI: 1.9-586.5, P = 0.02). The presence of branched vessels with rounded endings was positively associated with poromas but did not reach statistical significance (OR: 2.4, 95% CI: 0.8-6.5, P = 0.10). The presence of any of these five features was associated with a sensitivity and specificity of 62.8% and 82.0%, respectively. CONCLUSION: We identified dermoscopic features that are specific to the diagnosis of poroma. Overall, however, the prevalence of these features was low. Significant clinical and dermoscopic variability is a hallmark of these uncommon tumours, which are most prevalent on non-acral sites.
Asunto(s)
Dermoscopía , Poroma/diagnóstico por imagen , Neoplasias de las Glándulas Sudoríparas/diagnóstico por imagen , Adulto , Anciano , Estudios de Casos y Controles , Estudios Transversales , Femenino , Humanos , Masculino , Persona de Mediana Edad , Curva ROCAsunto(s)
Carcinoma Basocelular/diagnóstico por imagen , Poroma/diagnóstico por imagen , Neoplasias Cutáneas/diagnóstico por imagen , Neoplasias de las Glándulas Sudoríparas/diagnóstico por imagen , Anciano , Dermoscopía , Diagnóstico Diferencial , Femenino , Humanos , Masculino , Microscopía Confocal , Persona de Mediana EdadAsunto(s)
Dermoscopía , Poroma/diagnóstico por imagen , Humanos , Masculino , Persona de Mediana EdadRESUMEN
Eccrine porocarcinoma (EPC) is a rare malignant skin tumor presumably arising from the intraepidermal ductal portion of the sweat gland. EPC occasionally mimics eccrine poroma (EP), seborrhea keratosis (SK), basal cell carcinoma (BCC), pyogenic granuloma (PG) and amelanotic melanoma with its clinical appearance as a pink nodule. Dermoscopy is an invaluable technique in diagnosing skin tumors. However, few cases of EPC have been reported using dermoscopic images, and their details were not well examined. Here, we present three histopathologically proven cases of EPC and summarize their dermoscopic findings together with five previously reported cases. None of the eight cases showed dermoscopic evidence indicative of SK (comedo-like openings, milia-like cysts, fissures and ridges, and hairpin vessels with white halo), BCC (blue-gray ovoid nests, multiple blue-gray globules, wheel-like structures, shiny white areas, leaf-like areas and arborizing vessels) or PG (reddish homogeneous area with collarette and white rail lines). A milky red area, which was suggestive of amelanotic melanoma, was not detectable in any cases. Seven cases exhibited a polymorphous vascular pattern mainly consisting of hairpin, linear-irregular and dotted vessels. A combination of round-to-oval pink-white structureless areas and white-to-pink halo was observed in five of eight cases, with one case showing the white-to-pink halo alone. Our investigation revealed that the dermoscopic characteristic of EP was also observed in discrete areas of EPC lesions. Thus, it is possible that the histopathological architecture of EPC contains portions of benign EP-like components. Awareness of this dermoscopic aspect of EPC may be helpful when diagnosing pink nodules.
Asunto(s)
Porocarcinoma Ecrino/diagnóstico por imagen , Poroma/diagnóstico por imagen , Neoplasias de las Glándulas Sudoríparas/diagnóstico por imagen , Anciano , Dermoscopía , Diagnóstico Diferencial , Porocarcinoma Ecrino/irrigación sanguínea , Porocarcinoma Ecrino/patología , Humanos , Masculino , Melanoma Amelanótico/diagnóstico por imagen , Melanoma Amelanótico/patología , Poroma/patología , Neoplasias Cutáneas/diagnóstico por imagen , Neoplasias Cutáneas/patología , Neoplasias de las Glándulas Sudoríparas/irrigación sanguínea , Neoplasias de las Glándulas Sudoríparas/patologíaRESUMEN
In a 61-year-old man with known poroma of right lower abdomen, malignant transformation to porocarcinoma was suspected and confirmed by biopsy. PET/CT was requested for tumor staging, which revealed high FDG uptake in the known skin nodules located in the right side of abdominal and chest wall and identified further some adenopathy in the right axillary. All nodules and axillary lymph nodes were removed, and diagnosis of eccrine porocarcinoma was confirmed. The primary tumor and secondary lesions of porocarcinoma show a high glucose metabolism; thus, PET/CT could be useful for staging, follow-up, and detection of recurrence of patients with eccrine porocarcinoma.