RESUMEN
Syphilis is an ancient sexually transmitted infection that plagues communities across the United States and the world. Cutaneous syphilis has a wide variety of manifestations and presentations, and is notoriously difficult to identify clinically as a result. In this report, we describe the case of a 30-year-old patient with condyloma lata on the umbilicus, an extremely rare site for the presentation of these lesions. With the recent surge in syphilis infections nationwide, including congenital infections, this case underscores the urgent necessity for heightened syphilis awareness and suspicion among clinicians.
Asunto(s)
Sífilis Cutánea , Ombligo , Adulto , Humanos , Antibacterianos/uso terapéutico , Sífilis Cutánea/diagnóstico , Sífilis Cutánea/tratamiento farmacológico , Sífilis Cutánea/microbiología , Sífilis Cutánea/patología , Resultado del Tratamiento , Treponema pallidum/aislamiento & purificación , Ombligo/microbiología , Ombligo/patologíaAsunto(s)
Sífilis , Humanos , Masculino , Sífilis/diagnóstico , Sífilis/tratamiento farmacológico , Sífilis/microbiología , Treponema pallidum/aislamiento & purificación , Antibacterianos/uso terapéutico , Resultado del Tratamiento , Adulto , Sífilis Cutánea/tratamiento farmacológico , Sífilis Cutánea/diagnóstico , Sífilis Cutánea/microbiología , Sífilis Cutánea/patología , Serodiagnóstico de la Sífilis , Biopsia , Piel/patología , Piel/microbiologíaRESUMEN
Cutaneous secondary syphilis presents with various manifestations, including condyloma lata (confluented moist papules). This article reports an unusual case of oral condyloma lata. A 56-year-old man presented with a 2-month history of foreign body sensation and sore throat. Physical examination revealed a hypertrophic, reddish-brown, flat-topped, moist plaque in the right amygdaloid fossa. This raised clinical suspicion of lymphoma. However, further enquiry revealed that the patient had extramarital sexual history with a female sex worker. Rapid plasma regain and Treponema pallidum particle agglutination tests were both positive. The patient's wife was diagnosed with early latent syphilis. Both the patient and his wife were treated with penicillin G benzathine, and the lesion in the male patient disappeared in 2 weeks. To the authors' knowledge, a single condyloma lata in the amygdaloid fossa mimicking lymphoma has not been reported previously. Awareness of the usual manifestations of syphilis can avoid unnecessary biopsy, and early diagnosis and treatment may prevent irreversible complications. Partner notification is very important to reduce the risk of transmission, and persistent or recurrent infection.
Asunto(s)
Condiloma Acuminado/etiología , Enfermedades de la Boca/etiología , Sífilis Cutánea/complicaciones , Sífilis/complicaciones , Femenino , Humanos , Masculino , Persona de Mediana Edad , Penicilina G Benzatina/uso terapéutico , Trabajadores Sexuales , Sífilis Cutánea/tratamiento farmacológicoRESUMEN
We describe a 17-year-old man who developed penile annular and scrotal eczematoid syphilids with penile chancre redux. Dermoscopy showed linear-irregular and hairpin vessels with white scales in annular lesions. Histopathology displayed psoriasiform hyperplasia with perivascular lymphoplasmacytic dermal infiltrate. Rapid plasma reagin and Treponema pallidumparticle agglutination assays were positive. The lesions disappeared after intramuscular benzathine penicillin.
Asunto(s)
Chancro/patología , Sífilis Cutánea/patología , Adolescente , Antibacterianos/uso terapéutico , Chancro/diagnóstico por imagen , Chancro/tratamiento farmacológico , Dermoscopía , Humanos , Masculino , Penicilina G Benzatina/uso terapéutico , Pene/diagnóstico por imagen , Pene/patología , Escroto/diagnóstico por imagen , Escroto/patología , Sífilis Cutánea/diagnóstico por imagen , Sífilis Cutánea/tratamiento farmacológico , Resultado del TratamientoAsunto(s)
Erupciones por Medicamentos , Exantema , Sífilis Cutánea , Sífilis , Erupciones por Medicamentos/diagnóstico , Erupciones por Medicamentos/etiología , Exantema/inducido químicamente , Exantema/diagnóstico , Humanos , Sífilis/diagnóstico , Sífilis/tratamiento farmacológico , Sífilis Cutánea/diagnóstico , Sífilis Cutánea/tratamiento farmacológicoRESUMEN
It is essential for health care providers to be familiared with the full spectrum of clinical presentations of syphilis. We present herein a case of syphilide psoriasiforme, an uncommon but well recognized clinical presentation of secondary syphilis. A 46-year-old HIV-infected female patient was referred to our attention with a presumptive diagnosis of palmoplantar psoriasis. On examination, there were exuberant pinkish-red papules and plaques covered with a thick silvery scale in the palms, flexor surfaces of the wrists, and the medial longitudinal arches of the feet. Serological and histopathological analyses uncovered the diagnosis of syphilis. Clinical remission was obtained after treatment. A detailed review of the literature on syphilide psoriasiforme, including descriptions from older syphilology textsis provided. The present case report emphasizes the need for clinicians to have a heightened awareness of the varied and unusual clinical phenotypes of syphilis.
Asunto(s)
Penicilina G Benzatina/administración & dosificación , Sífilis Cutánea/diagnóstico , Femenino , Humanos , Persona de Mediana Edad , Sífilis Cutánea/tratamiento farmacológico , Sífilis Cutánea/patologíaRESUMEN
INTRODUCTION: Untreated syphilis may lead to severe complications. This infection has recently re-emerged in developed countries with a high number of cases coinfected with human immunodeficiency virus. In these patients, the skin lesions of secondary syphilis can be very atypical. CASE PRESENTATION: We report the case of a 38-year-old Bulgarian homosexual man who was coinfected with human immunodeficiency virus and syphilis. His skin contained multiple extensive necrotic lesions with abundant purulent secretion that covered his face, lips, scalp, and torso. Initial clinical diagnoses included varicella pustulosa and staphylococcal dermatitis. Human immunodeficiency virus infection in our patient had been established 2 years earlier in prophylactic studies, but had not been treated. Due to lack of penicillin, he was successfully treated with ceftriaxone, and the skin lesions underwent complete reversal. He also began antiretroviral therapy, which resulted in a significant effect on his immune status. Three months after the onset of antiretroviral therapy, he also achieved optimal viral suppression. CONCLUSION: This case emphasizes the importance of considering cutaneous secondary syphilis in the differential diagnosis of any inflammatory cutaneous disorder in individuals infected with human immunodeficiency virus.