1.
J Adv Pharm Technol Res
; 15(2): 130-134, 2024.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38903550
RESUMO
The aim of the currnet study to examine the effect of subclinical hypothyroidism (SCH) in diabetic patients on coagulation parameters. This retrospective case-control study involves 130 patients diagnosed with type 2 diabetes mellitus (T2DM), divided into 65 T2DM with newly diagnosed SCH and 65 euthyroid (EUT) T2DM patients without SCH. Fibrinogen (FIB) was significantly higher in SCH (508.2 ± 63.0 mg/dL) than EUT (428.1 ± 44.8 mg/dL). In the SCH patients, FIB correlated with several parameters, such as age (ß = 0.396), body mass index (ß = 0.578), glycated hemoglobin (ß = 0.281), and activated partial thromboplastin time (ß = 0.276). In conclusion SCH in DM patients appears to increase the magnitude of coagulopathy.