[Thromboembolic disease: analysis of 239 cases]. / Enfermedad tromboembólica venosa: análisis de 239 casos.

AIM: To know the number of patients that are admitted in the hospital with TED or those who have developed it during their stay, analyzing how to manage this disease and make a basis for a prospective study of this disease. METHODS: It is a descriptive and retrospective study of TED diagnosed patients during their stay at the Hospital Clínico San Carlos of Madrid for a 6 month period. Data related with epidemiologic records, diagnosis, treatment and complications of patients with Deep-Vein Thrombosis (DVT), Pulmonary Thromboembolism (PTE) or both (DVT+PTE) are collected. RESULTS: From October 1st of 2003 to March 31st of 2004, 239 patients were diagnosed with TED (64 DVT, 125 PTE y 51 DVT + PTE) when they were discharged from our hospital, with an average age of 73.2 years (standard desviation 13.64). We classify as risky factors with significative statistical differences chemotherapy, acute myocardium infarction and obesity. It has not been found any relation between the treatment used and the development of hemorrhage. Patients with previous episodes of TED had more frequent hemorrhagies than those without such records. Hypokinesia in the right ventricle shown on the echocardiogram supposed a gloomy prognosis of the death for TED as well as the development of DVT + PTE. CONCLUSION: In more than a 50% of patients, TED was PTE and more than a 60% were women. It is important to obtain information about these patients because 2/3 of them are admitted to internal medicine. Chemotherapy, AIM and obesity were factors significatively associated to DVT, PTE and DVT + PTE. Hypokinesia in the right ventricle shown on the echocardiogram supposed a gloomy prognosis for TED as well as the development of DVT + PTE.

House dust mites and Der p I in Tenerife (Canary Islands, Spain): the relative importance of other non Dermatophagoides spp mites.

BACKGROUND: House dust mites constitute the major etiologic factor causing sensitization and asthma its geographical distribution map is quite well known, although it is not yet complete. Home environments world-wide show mites that mainly belong to the Piroglyphidae family, the D. pteronyssinus specie being the predominant one. However others have also been considered of interest. OBJECTIVE: The aim of this work was to study the species and to determine the levels of Der p I, Der f I and group II of allergens of Dermatophagoides. Present in houses from Tenerife, Canary Islands (Spain). METHODS: Dust samples were collected in 130 houses. RESULTS: D. pteronyssinus was found in 121 (95.3%) homes, being the predominant species in 113 (89%). In 69 (55%) homes, Dermatophagoides spp. were found together with other species from other generus. Mean values for Der p I were 13.7 +/- 13.88 (mean +/- SD), for Der f 1 1.05 +/- 1.83 and for the Group I of allergens 7 +/- 6.77. CONCLUSION: Although D. pteronyssinus is the predominant species in our area, there are others that may be off importance and should be taken into consideration in the diagnostic, home disallergenization and later treatment of patients.

[Vasculitis caused by hypersensitivity: an analysis of 60 patients]. / Vasculitis por hipersensibilidad: análisis de 60 pacientes.

Sixty cases of hypersensitivity vasculitis are revised analyzing their possible etiology, clinical course, analytical and histological alterations, evolution, and treatment. Thirty of these cases corresponded to Schönlein Henoch purpura (SH). The results of this subgroup (SH) are compared to other hypersensitivity vasculitis (HV).

[Disseminated intravascular coagulation in systemic lupus erythematosus]. / Coagulación intravascular diseminada en el lupus eritematoso sistémico.

A patient with systemic lupus erythematosus (SLE) who developed disseminated intravascular coagulation during the beginning of SLE is presented. No other cause responsible for the producing of DIC was found. After treatment with corticoids, and cyclophosphamide the DIC was rapidly settled. This case supports the need for a complete blood test in patients with SLE who show coagulation alterations.