RESUMO
OBJECTIVES: In patients with acute chest pain, we derived a cutpoint for ischaemia-modified albumin (IMA) and prospectively validated this cutpoint to predict 30-day major adverse cardiac events (MACEs). METHODS: We prospectively recruited a derivation cohort (18-month period) to establish a serum IMA cutpoint targeting 80% sensitivity. This was followed by a prospective validation cohort study of emergency department patients with acute chest pain at two university hospitals over a 3-month period. A MACE was defined as myocardial infarction, revascularisation or death at 30-day follow-up. RESULTS: In the derivation cohort of 151 patients, the IMA cutpoint that achieved 80% sensitivity for MACEs was 75 KU/litre. The sensitivity was prospectively validated in 171 patients consecutively enrolled, of whom 106 underwent multiple-biomarker analysis (19.8% MACE rate, 81% sensitivity of IMA). Furthermore, IMA by itself (81%, p<0.01) and in combination with initial highly sensitive cardiac troponin T (hsTnT) (90%, p<0.001) had significantly higher sensitivity than initial hsTnT (29%) for prediction of MACEs. CONCLUSIONS: We prospectively validated the sensitive IMA cutpoint of 75 KU/litre with 80% sensitivity for MACEs in patients with acute chest pain. Our data suggest that IMA alone and in combination with initial hsTnT are more sensitive than the initial hsTnT for MACEs.
Assuntos
Dor no Peito/etiologia , Isquemia Miocárdica/diagnóstico , Albumina Sérica/metabolismo , Adulto , Idoso , Biomarcadores/sangue , Dor no Peito/sangue , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Infarto do Miocárdio/diagnóstico , Revascularização Miocárdica , Valor Preditivo dos Testes , Prognóstico , Estudos Prospectivos , Fatores de Risco , Troponina T/sangue , Adulto JovemRESUMO
OBJECTIVES: Patient complaints to the emergency department (ED) have been well studied as indicators of quality. However, no study of complaints from healthcare providers (physicians, nurses and hospital administrators) has been published. Given their experience and expertise, healthcare providers are uniquely positioned to provide informed opinions about patient care. We present 1 year's results from a system initiated to capture healthcare providers' complaints, respond systematically, and integrate them into our quality program. METHODS: Complaints by healthcare providers to the ED for calendar year 2002 generated a "Care Concern" addressed by the involved emergency physician within 7 days. These were reviewed by two quality managers who assigned one of eight categories to the primary complaint and evaluated the need for formal peer review. RESULTS: Of 185 complaints, 53 (29%) were from healthcare providers. Of these, 31 (58%) related to medical care: 8 (15%) to diagnostic work-up, 9 (16%) to ED management, and 14 (26%) to consultations. Eleven (21%) related to miscommunication: 7 (13%) to disposition and 4 (8%) concerned infraction of hospital policy. Ten (19%) led to further formal review with two resulting in changes in ED policy. CONCLUSION: Healthcare workers' complaints highlight an aspect of customer care that is sometimes overlooked-that which we provide to other services. The complaints relate primarily to patient care issues, frequently raising concerns requiring intervention. This underused source of information presents a potential wealth of opportunity for quality improvement and customer service in the ED.
Assuntos
Atitude do Pessoal de Saúde , Medicina de Emergência/normas , Serviço Hospitalar de Emergência/normas , Auditoria Médica/métodos , Revisão dos Cuidados de Saúde por Pares , Indicadores de Qualidade em Assistência à Saúde , Gestão da Qualidade Total/métodos , Hospitais Universitários/normas , Humanos , Comunicação Interdisciplinar , Liderança , Política Organizacional , Admissão do Paciente/normas , Equipe de Assistência ao Paciente/normas , Alta do Paciente/normas , Transferência de Pacientes/normas , Guias de Prática Clínica como Assunto , Estados UnidosRESUMO
Painful conditions are a common cause for visits to emergency departments. Appropriate therapy often consists of sedating medications followed by a period of observation that is beneficial in assessing their effect. The cause of abdominal pain is frequently elusive, requiring prolonged testing and re-examination. Observation is particularly beneficial in assessing this condition, while certain other painful conditions are not suitable for emergency observation because of the need for prolonged treatment.
Assuntos
Analgésicos/uso terapêutico , Tratamento de Emergência/métodos , Observação/métodos , Dor Intratável/tratamento farmacológico , Dor Abdominal/tratamento farmacológico , Anemia Falciforme/tratamento farmacológico , Sedação Consciente/métodos , Serviço Hospitalar de Emergência/normas , Feminino , Humanos , Assistência de Longa Duração , Masculino , Dor Intratável/diagnóstico , Prognóstico , Índice de Gravidade de Doença , Fatores de Tempo , Estados UnidosRESUMO
An unacceptably high rate of medical error occurs in the emergency department (ED). Professional accountability requires that EDs be managed to systematically eliminate error. This requires advocacy and leadership at every level of the specialty and at each institution in order to be effective and sustainable. At the same time, the significant operational challenges that face the ED, such as excessive patient care requirements, should be recognized if error reduction efforts are to remain credible. Proper staffing levels, for example, are an important prerequisite if medical error is to be minimized. Even at times of low volume, however, medical error is probably common. Engineering human factors and operational procedures, promoting team coordination, and standardizing care processes can decrease error and are strongly promoted. Such efforts should be coupled to systematic analysis of errors that occur. Reliable reporting is likely only if the system is based within the specialty to help ensure proper analysis and decrease threat. Ultimate success will require dedicated effort, continued advocacy, and promotion of research.
Assuntos
Medicina de Emergência/normas , Serviço Hospitalar de Emergência/normas , Erros Médicos/prevenção & controle , Erros Médicos/estatística & dados numéricos , Gestão de Riscos/métodos , Atitude do Pessoal de Saúde , Serviço Hospitalar de Emergência/tendências , Humanos , Incidência , Equipe de Assistência ao Paciente/organização & administração , Competência Profissional , Medição de Risco , Responsabilidade Social , Estados Unidos/epidemiologiaRESUMO
Accurate measurement and interpretation of tuberculin skin tests is essential both to avoid unnecessary prophylactic treatment with potentially hepatotoxic drugs and to ensure the proper institution of therapy in tuberculin-positive individuals. Although two methods are currently used for reading tuberculin skin tests, palpation and ballpoint, the optimal technique has not been established. We compared measurements obtained by each method on 101 patients tested with intermediate tuberculin purified protein derivative. Fifty-eight of these patients were also tested using Mono-Vacc. Excellent interobserver agreement among the five raters was demonstrated for both the palpation and ballpoint techniques. There was no significant difference between the two methods for any reader using the normal 10-mm cutoff point for a positive intermediate tuberculin purified protein derivative test. For any individual observer the decision as to whether the test was positive or negative was unaffected by the method in at least 93% of readings. We conclude that readings by physicians using palpation and ballpoint methods are comparable for clinical decision making.