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Pak J Pharm Sci ; 31(4(Special)): 1707-1712, 2018 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-30203767

RESUMO

Gatifloxacin is a fourth-generation antibiotic and its antibacterial activity is better. It can play an obvious antiseptic effect in gram-positive bacteria, mycobacterium, mycoplasma, anaerobes and chlamydia. This study analyzed the treatment of the foreign body of the cornea by gatifloxacin eye drops. The results showed that gatifloxacin has a high bacterial clearance rate, which can reach 96.1%. The clinical effect is accurate and the adverse reaction is less. Compared with the control drug levofloxacin, its efficacy and safety were not statistically significant. Moreover, MIC determination of bacteria isolated from the study showed that gatifloxacin had stronger antibacterial activity. At the same time, it can be seen that nursing intervention can effectively improve the satisfaction of the treatment, before the operation, the patient's eye abnormalities, the psychological status of the patient, and the suitability of drug allergy should be evaluated.


Assuntos
Corpos Estranhos no Olho/tratamento farmacológico , Gatifloxacina/uso terapêutico , Adolescente , Adulto , Antibacterianos/efeitos adversos , Antibacterianos/uso terapêutico , Corpos Estranhos no Olho/enfermagem , Gatifloxacina/efeitos adversos , Humanos , Levofloxacino/efeitos adversos , Levofloxacino/uso terapêutico , Testes de Sensibilidade Microbiana , Pessoa de Meia-Idade , Soluções Oftálmicas/efeitos adversos , Soluções Oftálmicas/uso terapêutico , Satisfação do Paciente , Adulto Jovem
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