RESUMO
The content of zinc, cobalt, and selenium in the intestinal wall of Leghorn chickens infected with Ascaridia galli was determined by nondestructive neutron-activation analysis. A comparison was made between the infected animals that were treated with Piperathrine and those that were given microelements or those that did not receive microelements. Age-dependent changes were found in the content of the microelements in the control groups. It is concluded that zinc, cobalt, and selenium are unevenly distributed in the intestinal tissues, with a dominating density of selenium occurring in the epithelial layer of the intestinal mucosa.
Assuntos
Antinematódeos/uso terapêutico , Ascaridia , Ascaridíase/tratamento farmacológico , Ascaridíase/metabolismo , Mucosa Intestinal/metabolismo , Piperazinas/uso terapêutico , Oligoelementos/metabolismo , Animais , Galinhas , Cobalto/metabolismo , Intestinos/efeitos dos fármacos , Análise de Ativação de Nêutrons , Selênio/metabolismo , Fatores de Tempo , Oligoelementos/análise , Zinco/metabolismoRESUMO
The content of nine microelements has been investigated in a parasite-host system by nondestructive neutron activation analysis. A mathematical model has been proposed for the development of Ascaridia galli in the "Leghorn" chicks intestines and for the microelement content dynamics under combined treatment with antiparasite agent and microelements. An analytical solution of the system of nonlinear differential equations has been obtained for the case of simple invasion. The model explains well the experimentally observed process of the change in the microelement content. The recovery constant has been introduced for the damaged by the helminthosis tissue and its value has been determined.
