RESUMO
INTRODUCTION: Isolated splenic metastases from a bronchial carcinoma, without other visceral metastatic involvement, are exceptionally uncommon. CASE REPORT: The authors report the finding of an isolated splenic metastasis 21 months after a left pneumonectomy for an undifferentiated large cell carcinoma, initially staged pT3N1M0. The splenic metastasis presented as a major deterioration in general health and sharp pains in the left hypochondrium. Splenectomy confirmed the metastatic nature of the splenic tumour and relieved the severe abdominal pains. Two years after the splenectomy and with out adjuvant treatment the patient remains in complete remission. CONCLUSION: Splenectomy for a metastasis from a bronchial carcinoma should avoid the later complications of this type of metastasis: severe abdominal pain, splenic rupture and compression of neighbouring vessels. If the bronchial carcinoma is controlled locally and the splenic metastasis is isolated, splenectomy offers, perhaps, a further chance of prolonged survival.
Assuntos
Carcinoma de Células Grandes/patologia , Neoplasias Pulmonares/patologia , Neoplasias Esplênicas/secundário , Idoso , Humanos , Masculino , Esplenectomia , Neoplasias Esplênicas/diagnóstico , Neoplasias Esplênicas/cirurgiaRESUMO
We report the observation of a sudden infant death in which autopsy revealed a focal pancreatic lesion called adenomatous hyperplasia. Histopathological and immunohistochemical characteristics of this lesion are detailed. Adenomatous hyperplasia and endocrine cell dysplasia are the two pancreatic lesions responsible for hyperinsulinemic hypoglycemia in infants, with a possible fatal evolution. An organic pancreatic lesion is exceptionally reported in observations of sudden infant death. These observations and ours point out the necessity of a meticulous post-mortem examination of the pancreas in sudden infant death.
Assuntos
Adenoma/patologia , Hiperinsulinismo/patologia , Neoplasias Pancreáticas/patologia , Morte Súbita do Lactente/patologia , Evolução Fatal , Feminino , Humanos , Hiperinsulinismo/complicações , Hiperplasia , Recém-Nascido , Morte Súbita do Lactente/etiologiaAssuntos
Meningioma/patologia , Couro Cabeludo/patologia , Neoplasias Cutâneas/patologia , Adulto , Humanos , MasculinoAssuntos
Doenças Mamárias/patologia , Malacoplasia/patologia , Idoso , Idoso de 80 Anos ou mais , Feminino , HumanosRESUMO
Primary malignant lymphoma of the bladder is infrequent and usually has a low malignancy, with a possibility of long-lasting remission. Our case is that of a 73-year-old woman who presented with a tumor of the bladder revealed by hematuria. She was treated with incomplete endoscopic resection, which showed that the lesion was a B cell lymphoma. After a complementary 60-Gy radiation therapy, remission was complete at 6 months. The histological and immunological study showed the lymphomatous proliferation infiltrating the chorion and the expression of the usual B-lymphocytic markers by the tumoral cells. Lymphoma of the bladder was described for the first time in 1885, and only a few small series of vesical lymphomas have been published since then. The prognosis is usually favorable owing to long-lasting remission. Complete surgical resection does not improve the results, and radiation therapy is the treatment of choice.
Assuntos
Linfoma de Células B/patologia , Neoplasias da Bexiga Urinária/patologia , Idoso , Terapia Combinada , Endoscopia/métodos , Feminino , Hematúria/etiologia , Humanos , Linfoma de Células B/complicações , Linfoma de Células B/radioterapia , Linfoma de Células B/cirurgia , Neoplasias da Bexiga Urinária/complicações , Neoplasias da Bexiga Urinária/radioterapia , Neoplasias da Bexiga Urinária/cirurgiaRESUMO
The authors report a case of epithelioid hemangioendothelioma of the azygos vein diagnosed during the investigation of a superior vena cava syndrome. Venography and thoracic CT and nuclear magnetic resonance scans showed an endovenous tumour with spinal and lymph node invasion. Cavographic-controlled biopsies allowed histological identification of the tumour. Palliative therapy consisted in tumour ablation and superior vena cava bypass. Epithelioid hemangioendothelioma is a rare vascular tumour characterised by the presence of epithelioid endothelial cells. It is slowly progressive and its potential malignancy justifies surgical excision whenever possible.
Assuntos
Veia Ázigos/patologia , Hemangioma , Síndrome da Veia Cava Superior/etiologia , Doenças Vasculares , Prótese Vascular , Células Epitelioides/patologia , Hemangioma/complicações , Hemangioma/diagnóstico , Hemangioma/patologia , Hemangioma/terapia , Humanos , Espectroscopia de Ressonância Magnética , Masculino , Flebografia , Síndrome da Veia Cava Superior/diagnóstico por imagem , Tomografia Computadorizada por Raios X , Doenças Vasculares/complicações , Doenças Vasculares/diagnóstico , Doenças Vasculares/terapia , Veia Cava SuperiorRESUMO
The authors report the case of a 62-year-old woman in whom, 18 months following the development of bilateral parotid hypertrophy followed by a dry syndrome, there was the onset of an angioimmunoblastic lymphadenopathy (AIL) which consisted of the association of a multiple lymphadenopathy with a characteristic histological appearance, although poor in plasmocytes, and a febrile syndrome, but in the absence of a complete syndrom from a laboratory standpoint. This fact, incombination with the richness of the nodes in epitheloid cells, is such that this case resembles the type II "dysimmune and pseudo-lymphomatous lymphadenopathies" (DPLL) of Delsol et al. Although the term AIL has never been used before in the title of previous publications of pseudo-lymphomas occuring during Sjögren's syndrome, it would seem possible, as has already been suggested by Diebold et al. (3) with regard to several cases, that certain of these pseudo-lymphomas are true AIL. The rapidly fatal course with visceral spread shown at autopsy and above all the presence of exclusively immunoblastic plaques in several mode areas led, on the basis of the criteria of Nathwani et al. (22), to acceptance of the coexistence of an immunoblastic sarcoma.
Assuntos
Linfadenopatia Imunoblástica/patologia , Idoso , Diagnóstico Diferencial , Feminino , Humanos , Linfadenopatia Imunoblástica/diagnóstico , Linfadenopatia Imunoblástica/imunologia , Imunoglobulinas/análise , Linfonodos/imunologia , Linfonodos/patologia , Síndrome de Sjogren/diagnósticoRESUMO
Brain lymphosarcoma may be divided into the circumscribed forms, surrounded by marked oedema with fibrin, and the diffuse or infiltrating forms. Cytology of the former is more uniformly lymphocytic, its clinical course is more rapidly fatal. Anatomically primary diffuse lymphosarcoma of the brain may be secondary to 'cured' systemic lymphoma.