[Activity of endogenous proteinases in glomerulonephritis in children]. / Aktivnost' éndogennykh proteinaz pri glomerulonefrite u detei.

Protease activities in serum and urine of 116 children with glomerulonephritis and 16 healthy children were tested using chromogenic peptide substrates Z-Dala_Leu-Arg-pNA and Glp-Ala-ALa-Leu-pNa. We found the dependence between activity of serine proteinases and clinical, morphological forms of primary glomerulonephritis and hypertension.

Clinical application of the polyunsaturated n-3 fatty acids usage in pediatric practice.

The investigation of the effectiveness of a diet supplemented with n-3 PUFA in children with glomerulonephritis was done. Patients receiving "Polyen" achieved better clinical remission, more rapid decrease of hypercholesterolemia, and hypercoagulation than the patients from the control group. We can recommend "Polyen" usage in the treatment of glomerulonephritis in children.

[Use of the fish oil "Polyen" in pediatric practice]. / Opyt primeneniia ryb'ego zhira "polien" v pediatricheskoi praktike.

The effects of supplementation of basic diets with 'Polyen' in daily doses of 2.5-4.0 g during 30-40 days together with antioxidants were studied in patients with kidney diseases (diet No7, n = 14), different allergies (hypoallergenic diet, n = 37) and in control children (n = 12). It was shown positive dynamics in fatty acid contents in plasma and red blood cell membranes, in humoral and cell immunity indicators and in improving of clinical symptoms of diseases. 'Polyen' is recommended for wide use in pediatric practice.