RESUMO
The purpose was to observe the changes in a rat pineal gland using stereological techniques during lactation and post-weaning periods. Thirty Wistar albino rats were studied during different post-natal periods using light microscopy. Pineal gland volume was estimated using the Cavalieri Method. Additionally, the total number of pinealocytes was estimated using the optical fractionator technique. Pineal gland volume displayed statistically significant changes between lactation and after weaning periods. A significant increase in pineal gland volume was observed from post-natal day 10 to post-natal day 90. The numerical density of pinealocytes became stabilized during lactation and decreased rapidly after weaning. However, the total number of pinealocytes continuously increased during post-natal life of all rats in the study. However, this increment was not statistically significant when comparing the lactation and after weaning periods. The increase in post-natal pineal gland volume may depend on increment of immunoreactive fibres, capsule thickness or new synaptic bodies.
Assuntos
Glândula Pineal/anatomia & histologia , Glândula Pineal/crescimento & desenvolvimento , Animais , Feminino , Lactação , Glândula Pineal/citologia , Ratos , Ratos Wistar , DesmameRESUMO
A single coronary ostium with no associated congenital cardiac disease is a rare congenital coronary-artery anomaly. However, a single right coronary artery has a much rarer incidence. We report here the antemortem diagnosis of a case with R-I subtype single coronary artery supplying the entire myocardium. A 36-year-old female with chest pain and dyspnea on exertion was admitted to the hospital, whose coronary angiography revealed a single, large coronary artery originating in the right aortic sinus. No observable change was detected in her electrocardiogram and her angiographic examination did not reveal any significant luminal narrowing although she experienced chest pain and dyspnea on exertion. R-I type of single coronary artery is an anomaly with a very rare incidence, which may cause myocardial ischemia and sudden death and whose recognition might be of use to physicians when diagnosing and treating this anomaly.
Assuntos
Anomalias dos Vasos Coronários/diagnóstico por imagem , Vasos Coronários/anatomia & histologia , Adulto , Dor no Peito/etiologia , Angiografia Coronária , Eletrocardiografia , Feminino , HumanosAssuntos
Anormalidades Múltiplas/diagnóstico , Átrios do Coração/anormalidades , Cardiopatias Congênitas/diagnóstico , Ventrículos do Coração/anormalidades , Anormalidades Múltiplas/terapia , Feminino , Cardiopatias Congênitas/terapia , Humanos , Pessoa de Meia-Idade , Marca-Passo Artificial , Síndrome , Resultado do TratamentoRESUMO
To assess the clinical significance of Körner's septum (KS) or petrosquamosal (PS) lamina in different chronic ear pathologies, a surgical and anatomic study was carried out, in which the significance of KS was assessed in various otologic diseases. Of 639 patients who underwent ear surgery between 1998 and 2001, 426 were included in the study. The diagnoses were chronic otitis media without cholesteatoma (COM), tympanosclerosis (TS), adhesive otitis media (AOM) and cholesteatoma (COL) in 160, 100, 70 and 96 patients respectively. The operative records of the patients were reviewed for the presence of KS. There was antral blockage by KS in all patients who also had Cog (the middle portion of the PS lamina). KS was mostly seen in cases of TS. The prevalence of KS was not significantly different when the result of the COM group was compared with that of the COL and AOM groups ( p>0.05). The prevalence of KS was significantly higher in patients with TS than in those with COM. Both antral and epitympanic blockages were more prevalent in cases of TS than in those of COM (chi(2) =3.9, p =0.04 and chi(2) =6.6, p =0.01 respectively). There is a significant association between the presence of KS and TS. Based on this finding, it is recommended that a mastoidectomy be performed in cases of severe tympanosclerosis in order to remove KS. How the removal of this anatomic impact will affect the natural course of the disease is still a question that needs further investigation.
Assuntos
Otopatias/patologia , Orelha Média/patologia , Adolescente , Adulto , Criança , Colesteatoma da Orelha Média/patologia , Doença Crônica , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Otite Média/patologia , Osso Petroso/patologia , Osso Temporal/patologiaRESUMO
The aim of this study was to determine dimensions of the normal menisci in 174 healthy subjects by using MRI. The menisci were divided into three zones (anterior horn, mid-body, posterior horn). The height and width of the both menisci were measured. For the medial meniscus; the height and width of the anterior horn were 5.32 mm and 7.78 mm, the height and width of the mid-body were 5.03 mm and 7.37 mm, and the height and width of the posterior horn were 5.53 mm and 11.71 mm, respectively. For the lateral meniscus, the height and width of the anterior horn were 4.33 mm and 8.88 mm, the height and width of the mid-body were 4.94 mm and 8.37 mm, and the height and width of the posterior horn were 5.36 mm and 9.70 mm, respectively. Three cases (1.7%) of discoid lateral meniscus were encountered. The results of this study should help to establish standard measurements, and to differentiate between normal and pathologic conditions of the menisci of the knee joint.
Assuntos
Imageamento por Ressonância Magnética/métodos , Meniscos Tibiais/anatomia & histologia , Adolescente , Adulto , Estudos de Coortes , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Probabilidade , Valores de Referência , Sensibilidade e EspecificidadeRESUMO
A coronary artery fistula is a direct communication between a coronary artery and one of the cardiac chambers or vessels around the heart. The present study was undertaken to define the incidence, clinical findings and angiographic characteristics of congenital coronary artery fistula in Turkish adults who underwent diagnostic cardiac angiography. A consecutive series of 11,350 coronary angiography, performed between January 2000 and December 2001, was retrospectively examined for the presence of coronary artery fistulas. The incidence of congenital coronary artery fistulas was 0.08%. All the patients had chest pain during exertion or at rest. All the fistulas were single and most arose from the proximal left anterior descending coronary artery and drained into the pulmonary artery. All the fistulas were small. Surgical treatment was not indicated. A congenital coronary artery fistula in adults is a distinct though rare entity, variable in its incidence and commonly associated with coronary artery obstructive disease. Diagnosis is mostly incidental during routine coronary angiography.
Assuntos
Cardiopatias Congênitas/diagnóstico por imagem , Fístula Vascular/diagnóstico por imagem , Adulto , Idoso , Idoso de 80 Anos ou mais , Dor no Peito/etiologia , Angiografia Coronária/métodos , Feminino , Cardiopatias Congênitas/epidemiologia , Humanos , Incidência , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Turquia/epidemiologia , Fístula Vascular/epidemiologiaRESUMO
Endoscopic endonasal surgery has been performed in children. Therefore, we need to know the precise anatomy and anatomic variations of the lateral nasal wall. This is important in order to achieve better surgical results and avoid complications. We also need to know the relationship between the anatomic variations and sinonasal disease. For the purpose of this study we assessed the anatomic variations of the lateral nasal wall and the association of these variations with chronic sinusitis in children. Forty-seven children with chronic sinus disease were included in the study. There were 25 female and 22 male patients with ages ranging from 2 to 16 years (mean 10.5+/-3.8 years). On coronal and axial computed tomographic (CT) scans, the anatomic variations of the lateral nasal wall and sinusitis were assessed. A pneumatized middle concha (MC) was the most common anatomic variation, followed by pneumatization of the superior concha (SC), Haller cell and agger nasi cell. Secondary MC, large ethmoidal bulla, maxillary sinus hypoplasia, Onodi cell, and uncinate process pneumatization were relatively rare. Maxillary sinusitis was the most common sinus infection, followed by ethmoidal, sphenoidal and frontal sinusitis in that order. There was no significant relationship between the sinusitis and anatomic variations except for some minor associations. In conclusion, anatomic variations in the lateral nasal wall are common in children. Local, systemic or environmental factors appear to be more important in pediatric sinusitis than the anatomic variations. Due to the absence of a definitive relationship between the anatomic variations and sinus disease, aggressive surgical interventions should be avoided while performing endonasal endoscopic surgery in the children.
Assuntos
Seios Paranasais/anatomia & histologia , Sinusite/diagnóstico por imagem , Adolescente , Criança , Pré-Escolar , Doença Crônica , Feminino , Humanos , Masculino , Seios Paranasais/diagnóstico por imagem , Sinusite/patologia , Sinusite/cirurgia , Tomografia Computadorizada por Raios X/métodosRESUMO
Our aim was to assess the anatomic localization, dimensions and incidence of the transverse and meniscofemoral ligaments, which can show anatomic variations or be mistaken for some pathologic conditions. In 100 healthy subjects (52 female, 48 male) whose ages ranged from 12 to 84 years, sagittal and coronal magnetic resonance images of the knee were obtained. There was at least one anterior or posterior meniscofemoral ligament in 82 cases. The anterior meniscofemoral ligament was present in 8 of the female and 4 of the male subjects. The posterior meniscofemoral ligament was found in 20 female and 22 male subjects. Both the anterior and posterior meniscofemoral ligaments were present in 15 female and 13 male subjects. The transverse ligament of knee was encountered in 19 female and 12 male subjects. In the females, average lengths of the anterior and posterior meniscofemoral ligaments were 9.87 +/- 4.79 mm and 25.60 +/- 5.50 mm, respectively. The corresponding values in the males were 11.11 +/- 2.57 mm and 28.80 +/- 5.49 mm, respectively. In the females, average width of the anterior and posterior meniscofemoral ligaments were 2.45 +/- 1.02 mm and 2.30 +/- 1.15 mm, respectively. The corresponding values in the males were 2.52 +/- 0.87 mm and 2.30 +/- 1.15 mm, respectively. On MRI assessment, in order to differentiate intra-articular lesions such as osteochondral and meniscal fragments or pseudotear of the lateral meniscus from the normal ligamentous anatomy of knee, the orientation and characteristic localization of the meniscofemoral ligaments should be taken into account. The French version of this article is available in the form of electronic supplementary material and can be obtained by using the Springer LINK server located at http://dx.doi.org/10.1007/s00276-002-0023-8.
Assuntos
Articulação do Joelho/anatomia & histologia , Ligamentos Articulares/anatomia & histologia , Imageamento por Ressonância Magnética , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Criança , Feminino , Humanos , Masculino , Pessoa de Meia-IdadeRESUMO
More than one notch and/or foramen may be found in the supraorbital region due to branching of the supraorbital nerves and vessels. A total of 360 adult Anatolian-Ottoman skulls (212 male, 148 female) were examined for some characteristics of the notches and/or foramina in the supraorbital region. The distribution of the supraorbital traits: 335 (93%) in medial, 24 (6.7%) in both medial and lateral, only 1 (0.3%) in lateral position. Of 360 skulls, 197 (54.7%) had one notch on either side, 32 (8.9%) had one foramen on one side and one notch on the other side, 24 (6.7%) had one foramen and notch on one side and one notch on the other side, 19 (5.3%) had one foramen on either side and 88 (24.4%) had other combinations. The distances of the notches from the midline, and between of the foramina from the midline and the supraorbital margin were measured. Knowledge of the anatomy of the supraorbital region is important for the plastic and maxillofacial surgery.
Assuntos
Órbita/anatomia & histologia , Feminino , Humanos , MasculinoAssuntos
Traumatismos em Atletas/diagnóstico por imagem , Fraturas Ósseas/diagnóstico por imagem , Ossos Sesamoides/lesões , Polegar/lesões , Adolescente , Traumatismos em Atletas/terapia , Feminino , Fraturas Ósseas/terapia , Humanos , Radiografia , Ossos Sesamoides/diagnóstico por imagem , Polegar/diagnóstico por imagemRESUMO
A variation of the brachial plexus characterized by the absence of the musculocutaneous nerve on both sides was observed during the dissection of a 72 year-old female cadaver. The long thoracic nerve included only the fibers from C5 and C6 on the left side. The musculocutaneous nerve was absent and two branches from the lateral cord innervated the coracobrachialis muscle. The median nerve innervated the biceps brachii and brachialis muscles in the arm and also gave off the lateral antebrachial cutaneous nerve. Additionally, a communicating branch was found from the median nerve to the ulnar nerve in the forearm. The knowledge of the anatomical variations of the peripheral nerve system can help give explanation when encountering an incomprehensible clinical sign.
Assuntos
Plexo Braquial/anormalidades , Antebraço/inervação , Nervo Musculocutâneo/anormalidades , Idoso , Cadáver , Feminino , Humanos , Nervo Mediano/anatomia & histologia , Músculo Esquelético/inervação , Nervo Ulnar/anatomia & histologiaRESUMO
The purpose of this study was to discover the prevalence of maxillary sinus hypoplasia (MSH) and associated malformations. A total of 490 consecutive axial and coronal computerized tomographic (CT) scans of the paranasal sinuses were obtained from patients with chronic sinusitis. CT scans were assessed for the presence of MSH and associated anatomic variations. A new classification of MSH was made, and the diagnostic criteria listed. The frequency of anatomic variations coexisting with MSH was also estimated. MSH was encountered in 21 (4.2%) of the 490 patients. Unilateral types I, II and III MSH were seen in 7 (1.4%), 6 (1.2%) and 8 (1.6%) respectively. MSH was bilateral only in 3 (0.6%) patients, one of which was a bilateral type II. In the remaining two bilateral MSH cases, there was a type II MSH on one side and type III MSH on the other in each patient. Middle conchal pneumatization was the most common coexisting anatomic anomaly in MSH, followed by agger nasi cell, secondary middle concha, paradoxical middle concha and superior conchal pneumatization. A patient with MSH should be carefully evaluated prior to any sinus surgery in order to avoid surgical complications. With precise CT assessments, an MSH can be diagnosed and distinguished from other maxillary sinus anomalies. With the additional criterion of orbital enlargement, and the help of reproducible measurement techniques explained in this study, an objective diagnosis and classification can be made in further investigations of MSH.
Assuntos
Seio Maxilar/anormalidades , Adolescente , Adulto , Idoso , Criança , Feminino , Humanos , Masculino , Seio Maxilar/diagnóstico por imagem , Seio Maxilar/cirurgia , Pessoa de Meia-Idade , Prevalência , Tomografia Computadorizada por Raios XRESUMO
Fracture of the thumb sesamoid bones is rare. We report here a fracture of the ulnar sesamoid in a 25-year-old man caused by a fall on his outstretched hand. He complained of pain and loss of thumb motion. Physical examination revealed tenderness, swelling, and a hematoma over the first metacarpal joint of the right thumb. Radiographs showed a fracture of the ulnar sesamoid which should not be confused with normal variants that occasionally arise from ossifications centers that fail to unite.
Assuntos
Articulação Metacarpofalângica/lesões , Ossos Sesamoides/lesões , Polegar/lesões , Fraturas da Ulna , Acidentes por Quedas , Adulto , Humanos , Masculino , Articulação Metacarpofalângica/diagnóstico por imagem , Radiografia , Ossos Sesamoides/diagnóstico por imagem , Polegar/diagnóstico por imagemRESUMO
In this study a total of 175 coronal CT scans of the nasal cavity and paranasal sinuses have been investigated. The uncinate bulla was detected in 21 (11 male and 10 female) cases of 175 patients. Out of 21, 17 were bilateral while 4 were unilateral. The incidence of the uncinate bulla was found as 12%.
Assuntos
Osso Etmoide/anormalidades , Seios Paranasais/anormalidades , Adolescente , Adulto , Osso Etmoide/diagnóstico por imagem , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Cavidade Nasal/diagnóstico por imagem , Seios Paranasais/diagnóstico por imagem , Sinusite/etiologia , Tomografia Computadorizada por Raios XRESUMO
In this study a total of 305 adult fibulae were examined to determine the number and location of the nutrient foramina in the shafts of bones. Of 305 fibulae, 281 had one foramen, 12 had two and the remaining 12 had no foramen. The foramina were seen primarily on the posterior surface (48.36%) and in the middle third (98.00%) of the bone. The mean foraminal index of the fibula was found to be 48.14 +/- 0.46.
Assuntos
Fíbula/anatomia & histologia , Fíbula/irrigação sanguínea , Adulto , HumanosRESUMO
The effects of a 30 d period of undernutrition, followed in some animals by nutritional rehabilitation, on neuronal connectivity in adult rat cerebellum were investigated using the disector method. There was no significant difference between well fed (719 +/- 74, mean +/- S.E.) and undernourished (709 +/- 53) synapse-to-neuron ratios in 134-d-old rat cerebellar cortex, nor was there a significant difference in synapse-to-neuron ratios between control animals (941 +/- 71) and previously undernourished rats (813 +/- 42) at 175 d of age. However, the age-related changes were significant (P < 0.05) in the controls, but not in the experimental group. It may be that the period of undernutrition caused subtle changes in the rehabilitating group which reduced the capacity for growth seen in well fed, matched control animals.
Assuntos
Córtex Cerebelar/patologia , Vias Neurais/patologia , Distúrbios Nutricionais/patologia , Animais , Masculino , Neurônios/patologia , Ratos , Ratos Wistar , Sinapses/ultraestruturaRESUMO
In this study a total of 269 adult lower limb long bones were examined to determine the number and location of the nutrient foramina in the shafts of bones. The mean of foraminal index was 48.82 for femur, 33.17 for tibia, and 47.82 for fibula. The number of foramina noted were: two on the linea aspera in the middle third of the femur, one on the posterior surface of the upper third of the tibia, and one on the posterior surface of the middle third of the fibula.
Assuntos
Fêmur/irrigação sanguínea , Fíbula/irrigação sanguínea , Tíbia/irrigação sanguínea , Artérias , Cadáver , HumanosRESUMO
In this study a total of 175 coronal CT scans of the nasal cavity and paranasal sinuses have been investigated. A secondary middle concha was detected bilaterally in 12 (6.8%) out of 175 patients. In all cases, the ethmoidal infundibulum was placed anteroinferior to the lateral origin of the secondary middle concha. This structure did not obstruct the osteo-meatal complex in any of the 12 cases.